| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hualei Dai, Xinjin Zhang, Zhigang Yang, Jianmei Li, Jialin Zhen. Effects of Baicalin on Blood Pressure and Left Ventricular Remodeling in Rats with Renovascular Hypertension. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-26. PMID:28622281. |
the myocardial apoptosis was detected using the terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling method, and the expression of c/ebp homologous protein and caspase-3 was monitored by western blot. |
2018-03-26 |
2023-08-13 |
rat |
| Qin Zhang, Xin-Wei Dong, Jia-Ying Xia, Ke-Ying Xu, Zhe-Rong X. Obestatin Plays Beneficial Role in Cardiomyocyte Injury Induced by Ischemia-Reperfusion In Vivo and In Vitro. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-22. PMID:28472020. |
finally, we assessed cells apoptosis using flow cytometry and detected the concentrations of caspase-3, bax, and bcl-2 using western blot analysis. |
2018-03-22 |
2023-08-13 |
rat |
| Jianhua Li, Caiyan Bai, Junxia Guo, Wanqian Liang, Jingning Lon. NDUFA4L2 protects against ischaemia/reperfusion-induced cardiomyocyte apoptosis and mitochondrial dysfunction by inhibiting complex I. Clinical and experimental pharmacology & physiology. vol 44. issue 7. 2018-03-21. PMID:28429857. |
the apoptosis of h9c2 cells was evaluated by flow cytometry and the expression of bax and bcl-2 was detected by western blot. |
2018-03-21 |
2023-08-13 |
Not clear |
| Yun Luo, Shan Lu, Xi Dong, Lijia Xu, Guibo Sun, Xiaobo Su. Dihydromyricetin protects human umbilical vein endothelial cells from injury through ERK and Akt mediated Nrf2/HO-1 signaling pathway. Apoptosis : an international journal on programmed cell death. vol 22. issue 8. 2018-03-21. PMID:28612103. |
then, the anti-oxidative enzymes were tested by commercial kits and intracellular reactive oxygen species (ros) was measured by flow cytometry, cell apoptosis was determined by annexin-v/pi assay and apoptosis-related proteins were detected by western blot. |
2018-03-21 |
2023-08-13 |
human |
| Shu Nu Chang-Lee, Hsi-Hsien Hsu, Marthandam Asokan Shibu, Tsung-Jung Ho, Chih-Hao Tsai, Ming-Cheng Chen, Chuan-Chou Tu, Vijaya Padma Viswanadha, Wei- Wen Kuo, Chih-Yang Huan. E Pathology oncology research : POR. vol 23. issue 3. 2018-03-20. PMID:27757837. |
further the cells were transfected with pcmv-erβ and the consequences of erβ-overexpression on the pparα induced changes such as enhanced cell-proliferation and suppressed apoptosis were determined using western blot analysis and tunel assay. |
2018-03-20 |
2023-08-13 |
Not clear |
| Junnan Guo, Jinzhong Xu, Junshi Zhang, Lei A. Alteration of mice cerebral cortex development after prenatal exposure to cypermethrin and deltamethrin. Toxicology letters. vol 287. 2018-03-19. PMID:29407790. |
moreover, cypermethrin/deltamethrin-induced apoptosis of nerve cell was significantly higher in treated groups than that in control group by using flow cytometry, western blot and tunel. |
2018-03-19 |
2023-08-13 |
mouse |
| Xian Chen, Ying Liao, Dan Long, Ting Yu, Fang Shen, Xuechi Li. The Cdc2/Cdk1 inhibitor, purvalanol A, enhances the cytotoxic effects of taxol through Op18/stathmin in non-small cell lung cancer cells in vitro. International journal of molecular medicine. vol 40. issue 1. 2018-03-16. PMID:28534969. |
in this study, the cdk1 inhibitor, purvalanol a was applied to explore the relevance of cdc2 signaling and taxol sensitivity through analyses, such as cellular proliferation and apoptosis assays, elisa, western blot analysis and immunoprecipitation. |
2018-03-16 |
2023-08-13 |
Not clear |
| Hong-Xing Dang, Jing Li, Chengjun Liu, Yueqiang Fu, Fang Zhou, Lei Tang, Long Li, Feng X. CGRP attenuates hyperoxia-induced oxidative stress-related injury to alveolar epithelial type II cells via the activation of the Sonic hedgehog pathway. International journal of molecular medicine. vol 40. issue 1. 2018-03-16. PMID:28560441. |
the apoptosis of aecii cells was assayed by flow cytometry, and the mrna and protein expression levels of shh and ptc1 in the aecii cells were detected by reverse transcription-quantitative polymerase chain reaction (rt-qpcr), western blot analysis and immunofluorescence, respectively. |
2018-03-16 |
2023-08-13 |
rat |
| Fu-Qing Zhang, Wei Lu, Wen-Xiao Yuan, Xin L. Regulation of c-Jun N-Terminal Protein Kinase (JNK) Pathway in Apoptosis of Endothelial Outgrowth Cells Induced by Asymmetric Dimethylarginine. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-13. PMID:28546532. |
after jnk specific inhibitor (sp600125) was added, eocs apoptosis protein expressions were measured by western blot analysis. |
2018-03-13 |
2023-08-13 |
Not clear |
| Lin-Jun Wang, Zi-Heng Wu, Xiang-Tao Zheng, Jian-Yun Long, Yang-Min Dong, Xin Fan. Zinc Finger E-Box Binding Protein 2 (ZEB2) Suppress Apoptosis of Vascular Endothelial Cells Induced by High Glucose Through Mitogen-Activated Protein Kinases (MAPK) Pathway Activation. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-13. PMID:28551696. |
results the apoptosis of huvecs detected by flow cytometry and western blot revealed that zeb2 overexpression distinctly suppressed the apoptosis of huvecs induced by high glucose. |
2018-03-13 |
2023-08-13 |
human |
| Md Mostafizur Rahman, Rachael A Uson-Lopez, Md Tajuddin Sikder, Gongxun Tan, Toshiyuki Hosokawa, Takeshi Saito, Masaaki Kurasak. Ameliorative effects of selenium on arsenic-induced cytotoxicity in PC12 cells via modulating autophagy/apoptosis. Chemosphere. vol 196. 2018-03-12. PMID:29324385. |
furthermore, western blot analyses revealed that simultaneous exposure of both metals significantly inhibited autophagy which further suppressed apoptosis through positively regulation of key proteins; p-mtor, p-akt, p-foxo1a, p62, and expression of ubiquitin, bax, bcl2, nfкb, and caspases 3 and 9, although those are negatively regulated by arsenic. |
2018-03-12 |
2023-08-13 |
human |
| Judith Olejnik, Emily V Nelso. Analyzing Apoptosis Induction and Evasion in Ebola Virus-Infected Cells. Methods in molecular biology (Clifton, N.J.). vol 1628. 2018-03-09. PMID:28573624. |
in this chapter, we describe a western blot assay for the successful detection of apoptosis in ebola virus (ebov)-infected cells. |
2018-03-09 |
2023-08-13 |
Not clear |
| Judith Olejnik, Emily V Nelso. Analyzing Apoptosis Induction and Evasion in Ebola Virus-Infected Cells. Methods in molecular biology (Clifton, N.J.). vol 1628. 2018-03-09. PMID:28573624. |
the protocol includes all steps from cell culture, infection of cells, generation of lysates, and analysis using western blot to detect caspase cleavage as marker of apoptosis. |
2018-03-09 |
2023-08-13 |
Not clear |
| Junzhou Wu, Kaiyan Chen, Fanrong Zhang, Jiaoyue Jin, Nan Zhang, Dan Li, Lisha Ying, Wei Chen, Herbert Yu, Weimin Mao, Dan S. Overcoming Linsitinib intrinsic resistance through inhibition of nuclear factor-κB signaling in esophageal squamous cell carcinoma. Cancer medicine. vol 6. issue 6. 2018-03-08. PMID:28440057. |
after linsitinib treatment, the expressions of downstream signaling molecules and apoptosis pathways were measured by western blot. |
2018-03-08 |
2023-08-13 |
human |
| X J Ni, Z Q Xu, H Jin, S L Zheng, Y Cai, J J Wan. Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 51. issue 2. 2018-03-08. PMID:29267498. |
thereafter, cck-8 assay, flow cytometry, western blot, migration assay, reactive oxygen species (ros) assay, and elisa were carried out to respectively assess cell viability, apoptosis, migration, ros activity, and the release of inflammatory cytokines. |
2018-03-08 |
2023-08-13 |
human |
| Fei Zhao, Yong-Feng Wang, Lei Song, Jia-Xin Jin, Ya-Qing Zhang, Hong-Yun Gan, Ke-Hu Yan. Synergistic Apoptotic Effect of D-Fraction From Grifola frondosa and Vitamin C on Hepatocellular Carcinoma SMMC-7721 Cells. Integrative cancer therapies. vol 16. issue 2. 2018-03-06. PMID:27151580. |
western blot analysis revealed that the upregulation of bax, downregulation of bcl-2, activation of poly-(adp-ribose)-polymerase (parp), and the release of cytochrome c were observed in cells treated with the combination of dfp/vc, which showed that the mechanism of anticancer activity in the smmc-7721 hepatocarcinoma cells involved induction of apoptosis. |
2018-03-06 |
2023-08-13 |
human |
| Tarik Ghadban, Judith L Dibbern, Matthias Reeh, Jameel T Miro, Tung Y Tsui, Ulrich Wellner, Jakob R Izbicki, Cenap Güngör, Yogesh K Vashis. HSP90 is a promising target in gemcitabine and 5-fluorouracil resistant pancreatic cancer. Apoptosis : an international journal on programmed cell death. vol 22. issue 3. 2018-03-06. PMID:27878398. |
alterations in signaling pathway effectors and apoptosis upon hsp90 inhibition were determined by western blot analysis and annexin v/pi staining. |
2018-03-06 |
2023-08-13 |
Not clear |
| Jing Sun, Xin Zhang, Yang Sun, Zhi-Shu Tang, Dong-Yan Gu. Effects of Hylomecon vernalis ethanol extracts on cell cycle and apoptosis of colon cancer cells. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28393197. |
expression levels of apoptosis and cell cycle‑related proteins were assessed by western blot. |
2018-03-05 |
2023-08-13 |
human |
| Ting Xia, Ying-Nan Wang, Chuan-Xin Zhou, Li-Mei Wu, Yong Liu, Qian-Hong Zeng, Xiang-Long Zhang, Jia-Hui Yao, Min Wang, Jian-Pei Fan. Ginsenoside Rh2 and Rg3 inhibit cell proliferation and induce apoptosis by increasing mitochondrial reactive oxygen species in human leukemia Jurkat cells. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28440403. |
finally, the expression levels of numerous mitochondrial‑associated apoptosis proteins were assessed by western blot analysis. |
2018-03-05 |
2023-08-13 |
human |
| Yao Shi, Hong Jiang, Xiaobo Yan. PPARδ activation protects H9c2 cardiomyoblasts from LPS‑induced apoptosis through the heme oxygenase‑1‑mediated suppression of NF‑κB activation. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28440451. |
the protein level of heme oxygenase‑1 (ho‑1), cleaved caspase‑3 (cc3), apoptosis regulator bcl‑2 (bcl‑2), apoptosis regulator bax (bax) and nuclear factor‑κb (nf‑κb) p65 was measured by western blot analysis. |
2018-03-05 |
2023-08-13 |
rat |