| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hai-Ming Chen, Zheng-Quan Lai, Hui-Jun Liao, Jian-Hui Xie, Yan-Fang Xian, Yun-Long Chen, Siu-Po Ip, Zhi-Xiu Lin, Zi-Ren S. Synergistic antitumor effect of brusatol combined with cisplatin on colorectal cancer cells. International journal of molecular medicine. vol 41. issue 3. 2018-08-03. PMID:29328398. |
cell apoptosis were determined by flow cytometry and western blot analysis. |
2018-08-03 |
2023-08-13 |
Not clear |
| Yong Chai, Juhua Xiao, Shouhua Zhang, Yunyan Du, Zhipeng Luo, Xin Zhou, Kai Huan. High-mobility group protein B1 silencing promotes susceptibility of retinoblastoma cells to chemotherapeutic drugs through downregulating nuclear factor-κB. International journal of molecular medicine. vol 41. issue 3. 2018-08-03. PMID:29328447. |
moreover, following sirna hmgb1, sirna nc and ammonium pdtc treatment, the apoptosis of rb cells with vcr incubation was evaluated by hoechst staining, and the expression of cleaved caspase-3, cleaved poly(adp-ribose) polymerase (parp), beclin 1 and p62 were determined with western blot analysis. |
2018-08-03 |
2023-08-13 |
Not clear |
| Jiao Wang, Qiang Liu, Linnan Yang, Xiaofei Xia, Rongrong Zhu, Shengguang Chen, Mei Wang, Liming Cheng, Xianzheng Wu, Shilong Wan. Curcumin-Loaded TPGS/F127/P123 Mixed Polymeric Micelles for Cervical Cancer Therapy: Formulation, Characterization, and Journal of biomedical nanotechnology. vol 13. issue 12. 2018-07-30. PMID:29490752. |
in addition, western blot assays demonstrated that cur@npt100 were more potent than free cur at activating the mitochondria-mediated apoptosis pathway. |
2018-07-30 |
2023-08-13 |
Not clear |
| Yeli Li, Yiqi Li, Fuguo Shi, Lina Wang, Lisheng Li, Danli Yan. Osthole attenuates right ventricular remodeling via decreased myocardial apoptosis and inflammation in monocrotaline-induced rats. European journal of pharmacology. vol 818. 2018-07-27. PMID:29146527. |
to further investigate the roles of apoptosis and inflammation in the effects of ost on mct-induced rv remodeling, apoptosis-related factors and inflammatory-associated factors were examined by western blot. |
2018-07-27 |
2023-08-13 |
rat |
| Shuomin Wang, Kangsheng G. Insulin-like growth factor 1 inhibits autophagy of human colorectal carcinoma drug-resistant cells via the protein kinase B/mammalian target of rapamycin signaling pathway. Molecular medicine reports. vol 17. issue 2. 2018-07-27. PMID:29257307. |
the viability and apoptosis of hct-8 colon cancer cells were analyzed, and expression levels of relevant genes and proteins were investigated using reverse transcription-quantitative polymerase chain reaction and western blot analysis, respectively. |
2018-07-27 |
2023-08-13 |
human |
| Xiaoxu Li, Ruiyu Ding, Zewen Han, Zeyun Ma, Yixiang Wan. Targeting of cell cycle and let-7a/STAT3 pathway by niclosamide inhibits proliferation, migration and invasion in oral squamous cell carcinoma cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-26. PMID:29031202. |
in this study, we, for the first time, investigated the underlying mechanisms from cell cycle arrest and let-7a/stat3 axis through cck-8, cell cycle, apoptosis, wound healing, transwell invasion, generation of stable cell line, real-time pcr, and western blot assays using two oscc cell lines wsu-hn6 and tca83. |
2018-07-26 |
2023-08-13 |
Not clear |
| Jin Jiang, Zuguo Yuan, Yiqing Sun, Yuan Bu, Wenfeng Li, Zhenghua Fe. Ginsenoside Rg3 enhances the anti-proliferative activity of erlotinib in pancreatic cancer cell lines by downregulation of EGFR/PI3K/Akt signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-26. PMID:29035827. |
cell proliferation and colony formation assay, annexin v/pi apoptosis analysis, western blot analysis, immunohistochemistry and in vivo study were carried out. |
2018-07-26 |
2023-08-13 |
human |
| Zi-Zhou Yao, Ai-Xin Hu, Xiang-Sheng Li. DUSP19 regulates IL-1β-induced apoptosis and MMPs expression in rat chondrocytes through JAK2/STAT3 signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-26. PMID:29174854. |
the expression of dusp19, apoptosis markers, jak2/stat3 and phosphorylation of jak2/stat3 was measured by real-time pcr and/or western blot assay. |
2018-07-26 |
2023-08-13 |
rat |
| Jun Hua, Nuo Yin, Beibei Yang, Ji Zhang, Jianhua Ding, Yi Fan, Gang H. Ginkgolide B and bilobalide ameliorate neural cell apoptosis in α-synuclein aggregates. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-25. PMID:29054095. |
here we showed that aggregated recombinant human α-syn, but not α-syn monomers, triggered cell injury in cultured human neuroblastoma cell line sh-sy5y in an apoptosis way by using flow cytometry and western blot assay. |
2018-07-25 |
2023-08-13 |
human |
| Guo Liu, Wenhao Zhan. Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 51. issue 8. 2018-07-25. PMID:29898032. |
cell viability was measured using trypan blue exclusion method and cell apoptosis using flow cytometry and western blot. |
2018-07-25 |
2023-08-13 |
human |
| Yinghua Lv, Pengfei Zhang, Jiayin Guo, Zhendong Zhu, Xueliang Li, Dazhong Xu, Wenxian Zen. Melatonin protects mouse spermatogonial stem cells against hexavalent chromium-induced apoptosis and epigenetic histone modification. Toxicology and applied pharmacology. vol 340. 2018-07-24. PMID:29289671. |
we determined the effect of melatonin, one of the most powerful endogenous free radical scavengers and wide-spectrum antioxidants, in protecting sscs from cr(vi)-induced apoptosis and global histone modification by western blot analysis. |
2018-07-24 |
2023-08-13 |
mouse |
| Bijay Kumar Poudel, Biki Gupta, Thiruganesh Ramasamy, Raj Kumar Thapa, Shiva Pathak, Kyung Taek Oh, Jee-Heon Jeong, Han-Gon Choi, Chul Soon Yong, Jong Oh Ki. PEGylated thermosensitive lipid-coated hollow gold nanoshells for effective combinational chemo-photothermal therapy of pancreatic cancer. Colloids and surfaces. B, Biointerfaces. vol 160. 2018-07-23. PMID:28917152. |
physicochemical characterizations and biological studies of gns-l/gb were performed, with the latter using cytotoxicity assays, cellular uptake and apoptosis assays, live/dead assays, and western blot analysis of pancreatic cancer cell lines (mia paca-2 and panc-1). |
2018-07-23 |
2023-08-13 |
Not clear |
| Ying-Chuan Chen, Guan-Yu Zhu, Xiu Wang, Lin Shi, Ting-Ting Du, De-Feng Liu, Yu-Ye Liu, Yin Jiang, Xin Zhang, Jian-Guo Zhan. Anterior thalamic nuclei deep brain stimulation reduces disruption of the blood-brain barrier, albumin extravasation, inflammation and apoptosis in kainic acid-induced epileptic rats. Neurological research. vol 39. issue 12. 2018-07-23. PMID:28918702. |
then, samples were prepared for quantitative real-time pcr (qpcr), western blot, immunofluorescence (if) staining, and transmission electron microscopy to evaluate the disruption of the bbb, albumin extravasation, inflammation, and apoptosis. |
2018-07-23 |
2023-08-13 |
rat |
| Tianyu Zhai, Zhenyu Hei, Qiang Ma, Haibin Liang, Yi Xu, Yichi Zhang, Longyang Jin, Chao Han, Jiandong Wan. Shikonin induces apoptosis and G0/G1 phase arrest of gallbladder cancer cells via the JNK signaling pathway. Oncology reports. vol 38. issue 6. 2018-07-20. PMID:29039581. |
western blot assay showed that shikonin induced mitochondrial-dependent apoptosis via the jnk signaling pathway. |
2018-07-20 |
2023-08-13 |
mouse |
| Guanhua Qian, Li Wang, Xueling Zheng, Tinghe Y. Deactivation of cisplatin-resistant human lung/ovary cancer cells with pyropheophorbide-α methyl ester-photodynamic therapy. Cancer biology & therapy. vol 18. issue 12. 2018-07-20. PMID:29059002. |
western blot revealed an increase of caspase 3 and bax, and a decrease of bcl-2, demonstrating the occurrence of apoptosis. |
2018-07-20 |
2023-08-13 |
human |
| Juedan Li, Lin Zhao, Xiaomeng Zhao, Peng Wang, Yan Liu, Jianping Rua. Foxo1 Attenuates NaF-Induced Apoptosis of LS8 Cells through the JNK and Mitochondrial Pathways. Biological trace element research. vol 181. issue 1. 2018-07-18. PMID:28429284. |
the expression levels of foxo1, c-jun n-terminal kinase (jnk), and some well-known regulators of the mitochondrial pathway of apoptosis (cytoplasmic cytochrome c, cleaved caspase-9, cleaved caspase-3, bcl-2, and bax) were detected by quantitative real-time pcr, western blot, and immunofluorescence assay. |
2018-07-18 |
2023-08-13 |
Not clear |
| Zhenkai Lou, Xingguo Li, Xueling Zhao, Kaili Du, Xing Li, Bing Wan. Resveratrol attenuates hydrogen peroxide‑induced apoptosis, reactive oxygen species generation, and PSGL‑1 and VWF activation in human umbilical vein endothelial cells, potentially via MAPK signalling pathways. Molecular medicine reports. vol 17. issue 2. 2018-07-18. PMID:29207192. |
huvecs were pretreated with resveratrol for 2 h and incubated with hydrogen peroxide (h2o2) for 24 h prior to the evaluation of cell viability, ros generation, apoptosis and thrombosis‑associated marker expression by performing mtt assays, 2',7'‑dichlorofluorescin diacetate reagent, flow cytometry, and reverse transcription‑quantitative polymerase chain reaction (rt‑qpcr) and western blot analysis, respectively. |
2018-07-18 |
2023-08-13 |
human |
| Qi Xie, Ye Xu, Weinan Gao, Yong Zhang, Jing Su, Yanan Liu, Yuting Guo, Minghan Dou, Kebang Hu, Liankun Su. TAT‑fused IP3R‑derived peptide enhances cisplatin sensitivity of ovarian cancer cells by increasing ER Ca2+ release. International journal of molecular medicine. vol 41. issue 2. 2018-07-17. PMID:29207009. |
we also detected cell apoptosis using western blot analysis and flow cytometry. |
2018-07-17 |
2023-08-13 |
Not clear |
| Ping Chen, Yang Yuan, Tianying Zhang, Bo Xu, Qing Gao, Tianjun Gua. Pentosan polysulfate ameliorates apoptosis and inflammation by suppressing activation of the p38 MAPK pathway in high glucose‑treated HK‑2 cells. International journal of molecular medicine. vol 41. issue 2. 2018-07-17. PMID:29207166. |
incubation of hk‑2 cells with hg activated the p38 mapk pathway and, subsequently, as confirmed by western blot analysis and flow cytometry, increased cell apoptosis, which was blocked by pps. |
2018-07-17 |
2023-08-13 |
mouse |
| Hailian Wang, Wei Ge, Wen Jiang, Dong Li, Xiuli J. SRPK1‑siRNA suppresses K562 cell growth and induces apoptosis via the PARP‑caspase3 pathway. Molecular medicine reports. vol 17. issue 1. 2018-07-12. PMID:29138847. |
the roles of caspase‑3, poly (adp‑ribose) polymerase (parp), p53 and b-cell lymphoma (bcl)‑2/bcl‑2 associated x, apoptosis regulator (bax) proteins in the apoptosis of human k562 cells were further examined through western blot analysis. |
2018-07-12 |
2023-08-13 |
human |