| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lixue Zou, Jun Liu, Hougen L. Influence of protein kinase RIPK4 expression on the apoptosis and proliferation of chondrocytes in osteoarthritis. Molecular medicine reports. vol 17. issue 2. 2018-08-20. PMID:29257245. |
chondrocytes proliferation was detected by mtt assay, cell apoptosis was indicated using flow cytometry and wnt/β‑catenin signaling pathway related‑proteins were investigated using western blot analysis. |
2018-08-20 |
2023-08-13 |
Not clear |
| Jiamin Kong, Li Wang, Lu Ren, Yujing Yan, Yisen Cheng, Zhiying Huang, Feihai She. Triptolide induces mitochondria-mediated apoptosis of Burkitt's lymphoma cell via deacetylation of GSK-3β by increased SIRT3 expression. Toxicology and applied pharmacology. vol 342. 2018-08-20. PMID:29407771. |
moreover, we examined the mitochondrial membrane potential by jc-1 method and measured apoptosis related protein using western blot assay. |
2018-08-20 |
2023-08-13 |
mouse |
| Shui-ping Qiu, Hong-li Li, Hai-lian Shi, Hui Wu, Fei Huang, Bei-bei Zhang, Xiao-jun Wu, Zheng-tao Wan. [Notoginsenoside Ft1 down-regulates HIF-1α, inhibits cell proliferation, decreases migration and promotes apoptosis in breast cancer cells]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 51. issue 7. 2018-08-20. PMID:29897190. |
the effect of ft1 on expression of apoptosis related proteins, hif-1α, pi3k/akt/mtor/p70s6 k and mapk pathways was examined with western blot. |
2018-08-20 |
2023-08-13 |
Not clear |
| Ke Wang, Yuekun Zh. Dexmedetomidine protects against oxygen-glucose deprivation/reoxygenation injury-induced apoptosis via the p38 MAPK/ERK signalling pathway. The Journal of international medical research. vol 46. issue 2. 2018-08-17. PMID:29210287. |
cell proliferation, cell cycle, apoptosis, and the levels of proteins related to p38 mapk/erk signalling and apoptosis were evaluated using cell counting kit-8, flow cytometry, tdt-utp nick end labelling and western blot analysis, respectively. |
2018-08-17 |
2023-08-13 |
mouse |
| Ce Ji, Ying Zhao, You-Wei Kou, Hua Shao, Lin Guo, Chen-Hui Bao, Ben-Chun Jiang, Xin-Ying Chen, Jing-Wei Dai, Yu-Xin Tong, Ren Yang, Wei Sun, Qiang Wan. Cathepsin F Knockdown Induces Proliferation and Inhibits Apoptosis in Gastric Cancer Cells. Oncology research. vol 26. issue 1. 2018-08-15. PMID:28474574. |
nine degs in cancer-related pathways and three downstream genes in the apoptosis pathway were validated by western blot, which was mainly in agreement with the microarray data. |
2018-08-15 |
2023-08-13 |
Not clear |
| Hongwei Tang, Jiakai Zhang, Shengli Cao, Bing Yan, Hongbo Fang, Huapeng Zhang, Wenzhi Guo, Shuijun Zhan. Inhibition of Endoplasmic Reticulum Stress Alleviates Lung Injury Induced by Brain Death. Inflammation. vol 40. issue 5. 2018-08-15. PMID:28752363. |
the results of western blot and immunohistochemistry showed that apoptosis was observed in the lung tissues of bd rats. |
2018-08-15 |
2023-08-13 |
rat |
| Runchen Miao, Xinsen Xu, Zhixin Wang, Sushun Liu, Kai Qu, Wei Chen, Chang Li. Synergistic effect of nutlin-3 combined with aspirin in hepatocellular carcinoma HepG2 cells through activation of Bcl-2/Bax signaling pathway. Molecular medicine reports. vol 17. issue 3. 2018-08-14. PMID:29286113. |
apoptosis markers, including b‑cell lymphoma 2 (bcl‑2), bcl‑2‑associated x protein (bax), caspase‑3, caspase‑8 and caspase‑9 were estimated by western blot analysis at various time points. |
2018-08-14 |
2023-08-13 |
mouse |
| Z Q Fu, Q Zhou, S Zhu, W Li. Anti-tumor mechanism of IL-21 used alone and in combination with 5-fluorouracil in vitro on human gastric cancer cells. Journal of biological regulators and homeostatic agents. vol 32. issue 3. 2018-08-14. PMID:29921390. |
tunel assay was used to detect the effect of each group on the apoptosis of the gastric cancer cells, and western blot was used to detect the expression of caspase-3, caspase-8, bcl-2, and c-myc, which are the proteins related to apoptosis, after the drug effect in each group. |
2018-08-14 |
2023-08-13 |
human |
| Z Q Fu, Q Zhou, S Zhu, W Li. Anti-tumor mechanism of IL-21 used alone and in combination with 5-fluorouracil in vitro on human gastric cancer cells. Journal of biological regulators and homeostatic agents. vol 32. issue 3. 2018-08-14. PMID:29921390. |
the percentage of cell apoptosis increased, and the western blot showed that the expression of caspase-3, caspase-8, and c-myc, respectively, in the semi-combination group, the 5-fluorouracil group, and the combination group increased successively and that the successive increasing of c-myc was the most significant. |
2018-08-14 |
2023-08-13 |
human |
| Wen-Wei Zou, Su-Ping X. Galangin inhibits the cell progression and induces cell apoptosis through activating PTEN and Caspase-3 pathways in retinoblastoma. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-13. PMID:29136761. |
furthermore, flow cytometry, hoechst 33258 staining and western blot assays indicated that galangin could induce apoptosis through promoting caspase-3 pathway, which was, at least partly, dependent on pten expression. |
2018-08-13 |
2023-08-13 |
human |
| Dongkai Zhao, Zhiyu Jiang, Zhihui Wang, Jinliang Ga. Retinoid interferon-induced mortality19 (GRIM19) inhibits proliferation and invasion in rheumatoid arthritis fibroblast-like synoviocytes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 98. 2018-08-13. PMID:29306209. |
the expression of grim19 in synovial tissues and ra-fls was detected by real-time quantitative rt-pcr(qrt-pcr).the effects of grim19 on proliferation, migration, invasion, apoptosis, and inflammatory cytokines levels in ra-fls were determined using cck8, wound healing, transwell invasion, and flow cytometry assays, and enzyme-linked immunosorbent assay (elisa), respectively.grim19 and its related protein expression levels were determined by western blot. |
2018-08-13 |
2023-08-13 |
Not clear |
| Ou-Gen Liu, Xiao-Yan Xiong, Chun-Ming Li, Xian-Sheng Zhou, Si-Si L. Role of Xeroderma Pigmentosum Group D in Cell Cycle and Apoptosis in Cutaneous Squamous Cell Carcinoma A431 Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-08-13. PMID:29362353. |
material and methods to explore the role of xpd in a431 cells, we overexpressed xpd in a431 cells and performed mtt assay, flow cytometry, and western blot analysis to examine cell proliferation, cell apoptosis, and genes expression. |
2018-08-13 |
2023-08-13 |
Not clear |
| Gui-Wei Liu, Yan-Hua Liu, Guo-Sheng Jiang, Wei-Dan Re. The reversal effect of Ginsenoside Rh2 on drug resistance in human colorectal carcinoma cells and its mechanism. Human cell. vol 31. issue 3. 2018-08-10. PMID:29582366. |
after treating with ginsenoside rh2, the cell cycle distribution and cellular apoptosis were analyzed by flow cytometry, cell migration was determined by transwell migration assay, the expression of drug-resistance genes and proteins were evaluated using quantitative real-time polymerase chain reaction (qrt-pcr) and western blot, respectively. |
2018-08-10 |
2023-08-13 |
human |
| Jing Xu, Yaping Huai, Nan Meng, Yanhong Dong, Zhijuan Liu, Qianqian Qi, Ming Hu, Mingyue Fan, Wei Jin, Peiyuan L. L-3-n-Butylphthalide Activates Akt/mTOR Signaling, Inhibits Neuronal Apoptosis and Autophagy and Improves Cognitive Impairment in Mice with Repeated Cerebral Ischemia-Reperfusion Injury. Neurochemical research. vol 42. issue 10. 2018-08-07. PMID:28620824. |
the expressions of proteins associated with signaling, apoptosis and autophagy were assessed by quantitative pcr and western blot. |
2018-08-07 |
2023-08-13 |
mouse |
| Mingxia Lu, Zhenghua Fei, Ganlu Zhan. Synergistic anticancer activity of 20(S)-Ginsenoside Rg3 and Sorafenib in hepatocellular carcinoma by modulating PTEN/Akt signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-07. PMID:29156516. |
cell viability, clonogenic assay, apoptosis assay, western blot analysis, xenograft treatment and immunohistochemistry were carried out. |
2018-08-07 |
2023-08-13 |
human |
| Zhong-Hua Wang, Xin-Yong Sun, Chun-Lei Li, Yan-Ming Sun, Jia Li, Lan-Feng Wang, Zhu-Qin L. miRNA-21 Expression in the Serum of Elderly Patients with Acute Myocardial Infarction. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-08-06. PMID:29197221. |
apoptosis of human cardiac myocytes (hcm) was analyzed using fluorescence-activated cell sorting (facs), and protein expression of caspase-3 was detected using western blot. |
2018-08-06 |
2023-08-13 |
human |
| Qian Zhao, Jiawei Guan, Yuanhua Qin, Peng Ren, Zhiwei Zhang, Jian Lv, Shijie Sun, Cuili Zhang, Weifeng Ma. Curcumin sensitizes lymphoma cells to DNA damage agents through regulating Rad51-dependent homologous recombination. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-03. PMID:29080451. |
flow cytometry analysis showed curcumin promoted apoptosis and western blot analysis confirmed curcumin activated caspase3-dependent apoptosis. |
2018-08-03 |
2023-08-13 |
Not clear |
| Qiang Liu, Hui Yang, Shengnan Xu, Xuemei Su. Downregulation of p300 alleviates LPS-induced inflammatory injuries through regulation of RhoA/ROCK/NF-κB pathways in A549 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-03. PMID:29091886. |
mtt, flow cytometry, qrt-pcr and western blot assays were used to assess the effect of p300 on a549 cells viability, apoptosis and inflammatory cytokines expressions. |
2018-08-03 |
2023-08-13 |
Not clear |
| Yuling Tian, Xiao Liang, Yue W. The alternation of autophagy/apoptosis in CD4+CD25+Foxp3+ Tregs on the developmental stages of atherosclerosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-03. PMID:29136784. |
the expression levels of autophagy and apoptosis signaling related regulators were determined by flow cytomery, rt-qpcr, and western blot assays in the cd4+cd25+foxp3+ tregs isolated from apoe-/- and wt. |
2018-08-03 |
2023-08-13 |
mouse |
| Lei Jin, Yujia Cao, Tong Zhang, Peng Wang, Daofei Ji, Xuejiao Liu, Hengliang Shi, Lei Hua, Rutong Yu, Shangfeng Ga. Effects of ERK1/2 S-nitrosylation on ERK1/2 phosphorylation and cell survival in glioma cells. International journal of molecular medicine. vol 41. issue 3. 2018-08-03. PMID:29286066. |
caspase-3 western blot analysis and flow cytometry were employed to assess cell apoptosis. |
2018-08-03 |
2023-08-13 |
human |