| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nittiya Chowchaikong, Sirinun Nilwarangkoon, Surat Laphookhieo, Chantra Tanunyutthawongse, Ramida Watanapokasi. p38 inhibitor inhibits the apoptosis of cowanin-treated human colorectal adenocarcinoma cells. International journal of oncology. vol 52. issue 6. 2018-10-09. PMID:29620273. |
the expression levels of bcl2 apoptosis regulator (bcl‑2) family, mapk and akt serine/threonine kinase 1 (akt) pathway proteins following cowanin treatment were determined by western blot analysis. |
2018-10-09 |
2023-08-13 |
human |
| Xiaoming Zhong, Peng Li, Juan Li, Ruili He, Guanchang Cheng, Yanming L. Downregulation of microRNA‑34a inhibits oxidized low‑density lipoprotein‑induced apoptosis and oxidative stress in human umbilical vein endothelial cells. International journal of molecular medicine. vol 42. issue 2. 2018-10-09. PMID:29750293. |
cell viability, apoptosis and protein expression was determined by a cell counting kit‑8 assay, flow cytometry and western blot analysis, respectively. |
2018-10-09 |
2023-08-13 |
human |
| Ahmad Fadhlurrahman Ahmad Hidayat, Chim Kei Chan, Jamaludin Mohamad, Habsah Abdul Kadi. Dioscorea bulbifera induced apoptosis through inhibition of ERK 1/2 and activation of JNK signaling pathways in HCT116 human colorectal carcinoma cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 104. 2018-10-05. PMID:29860114. |
the lowest ic50 of the extract and fractions on selected cancer cells were selected for further apoptosis assay and western blot analysis. |
2018-10-05 |
2023-08-13 |
human |
| Ying Xin, Haiyan Zhang, Zhaotong Jia, Xiaoqian Ding, Yong Sun, Qiang Wang, Tao X. Resveratrol improves uric acid-induced pancreatic β-cells injury and dysfunction through regulation of miR-126. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 102. 2018-10-02. PMID:29710530. |
then, cell viability, apoptosis, apoptosis-associated factors, inos expression and insulin secretion were examined by cck-8, flow cytometry, western blot, qrt-pcr and glucose-stimulated insulin secretion (gsis), respectively. |
2018-10-02 |
2023-08-13 |
mouse |
| Jiaxiu Yin, Xinxin Li, Zaili Zhang, Xiaohua Luo, Li Wang, Lin Li. SPAG6 silencing induces apoptosis in the myelodysplastic syndrome cell line SKM‑1 via the PTEN/PI3K/AKT signaling pathway in vitro and in vivo. International journal of oncology. vol 53. issue 1. 2018-10-02. PMID:29749435. |
additionally, skm‑1 cells transduced with spag6 short hairpin rna (shrna) lentivirus were treated with the phosphatidylionositol 3-kinase (pi3k) inhibitor ly294002 or pan caspase inhibitor z‑vad‑fmk and the apoptosis rates were measured by flow cytometry, and the expressions of associated proteins were examined by western blot analysis. |
2018-10-02 |
2023-08-13 |
mouse |
| Guoqing Duan, Su Hou, Jianjun Ji, Bin Den. The study of sclareol in inhibiting proliferation of osteosarcoma cells by apoptotic induction and loss of mitochondrial membrane potential. Cancer biomarkers : section A of Disease markers. vol 22. issue 1. 2018-10-01. PMID:29562495. |
mg63 cells were then divided into control and drug treated group, for measuring apoptosis and mitochondrial membrane potential by flow cytometry, and the expression of cytochrome c, bax and bcl-2 by western blot. |
2018-10-01 |
2023-08-13 |
Not clear |
| Chenchen Li, Xia Zhao, Yang Yang, Siwen Liu, Yun Liu, Xiaoyou L. Interleukin-22 (IL-22) Regulates Apoptosis of Paclitaxel-Resistant Non-Small Cell Lung Cancer Cells Through C-Jun N-Terminal Kinase Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-09-28. PMID:29723165. |
cell apoptosis was analyzed by flow cytometry, and the c-jun n-terminal kinase (jnk) signal pathway was determined using western blot analysis. |
2018-09-28 |
2023-08-13 |
Not clear |
| Zhixian Fang, Wenyu Chen, Zuguo Yuan, Xinge Liu, Hao Jian. LncRNA-MALAT1 contributes to the cisplatin-resistance of lung cancer by upregulating MRP1 and MDR1 via STAT3 activation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 101. 2018-09-24. PMID:29505924. |
cell viability, colony formation assay, apoptosis analysis, western blot analysis, immunohistochemistry, and animal study were carried out. |
2018-09-24 |
2023-08-13 |
human |
| Qiang Feng, Tao Tian, Junfeng Liu, Li Zhang, Jiangang Qi, Xiaojuan Li. Deregulation of microRNA‑31a‑5p is involved in the development of primary hypertension by suppressing apoptosis of pulmonary artery smooth muscle cells via targeting TP53. International journal of molecular medicine. vol 42. issue 1. 2018-09-24. PMID:29620173. |
the results of the rt‑qpcr and western blot analyses showed that mir‑31a‑5p negatively regulated the expression of tp53, and transfection with the hsa‑mir‑31a‑5p mimic significantly promoted cell growth and inhibited cell apoptosis, whereas transfection with the anti‑hsa‑mir‑31a‑5p mimic significantly suppressed cell growth and induced cell apoptosis. |
2018-09-24 |
2023-08-13 |
rat |
| Quan Cao, Junxia Zhang, Ling Gao, Yijie Zhang, Mingyan Dai, Mingwei Ba. Dickkopf‑3 upregulation mediates the cardioprotective effects of curcumin on chronic heart failure. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568962. |
the effects of curcumin on dickkopf‑related protein 3 (dkk‑3), p38 mitogen‑activated protein kinase (p38), c‑jun n‑terminal kinase (jnk) and apoptosis signal‑regulating kinase 1 (ask1) were assessed by immunohistochemical staining and western blot analysis. |
2018-09-21 |
2023-08-13 |
Not clear |
| Yu Chen, Haifeng Zhuang, Xuerui Chen, Zheqi Shi, Xu Wan. Spermidine‑induced growth inhibition and apoptosis via autophagic activation in cervical cancer. Oncology reports. vol 39. issue 6. 2018-09-21. PMID:29693131. |
secondly, flow cytometry incorporating annexin v‑fitc/pi‑staining revealed that spermidine promoted the apoptosis of hela cells, and western blot analysis revealed that spermidine activated autophagy. |
2018-09-21 |
2023-08-13 |
Not clear |
| Linyu Zhou, Chunyan Bao, Xiao Hu, Yongqing Dai, Zhijun Ba. [LRIG1 promotes the apoptosis of pituitary tumor cells induced by cisplatin]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 34. issue 1. 2018-09-20. PMID:29595451. |
the cells of the two groups were induced by 20 g/ml ddp, and 48 hours later, the cell apoptosis was detected by flow cytometry; the proliferation capacity was tested by plate cloning experiment; and the relative expressions of apoptosis-related proteins bax, caspase-3 and bcl2 in the cells were examined by western blot analysis. |
2018-09-20 |
2023-08-13 |
human |
| Xiaoli Li, Jian Liu, Li Qian, Honggang Ke, Chan Yao, Wei Tian, Yifei Liu, Jianguo Zhan. Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy. Molecular and cellular biochemistry. vol 445. issue 1-2. 2018-09-17. PMID:29327288. |
cell viability, cell cycle, cell apoptosis, cell migration, and invasion were analyzed by mtt, flow cytometry, western blot analysis, wound healing assay, and transwell chamber assay. |
2018-09-17 |
2023-08-13 |
human |
| Tonghuai Li, Yan Chen, Jingjing Zhang, Shaoxiao Li. LncRNA TUG1 promotes cells proliferation and inhibits cells apoptosis through regulating AURKA in epithelial ovarian cancer cells. Medicine. vol 97. issue 36. 2018-09-17. PMID:30200102. |
cell counting kit-8 (ckk-8), annexin v-fitc (av)-propidium iodide (pi) (av-pi), quantitative polymerase chain reaction (qpcr), and western blot assays were performed to detect cells proliferation, apoptosis, rna expression, and protein expression respectively.cells proliferation was increased in lncrna tug1 mimic group and decreased in lncrna tug1 inhibitor group than normal control (nc) groups. |
2018-09-17 |
2023-08-13 |
Not clear |
| Yanfang Zhang, Chenang Lyu, Yu Liu, Yanpeng Lv, Tammy T Chang, Boris Rubinsk. Molecular and histological study on the effects of non-thermal irreversible electroporation on the liver. Biochemical and biophysical research communications. vol 500. issue 3. 2018-09-14. PMID:29678581. |
western blot was used to examine pro and cleaved caspase-3 (marker for apoptosis), pro and cleaved caspase-1 and gasdermin d (markers for pyroptosis), and rip3 and mlkl (markers for necroptosis). |
2018-09-14 |
2023-08-13 |
rat |
| Pei-Yi Chen, Hsin-Jung Tien, Shih-Fen Chen, Chi-Ting Horng, Huei-Lin Tang, Hui-Ling Jung, Ming-Jiuan Wu, Jui-Hung Ye. Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein. International journal of molecular sciences. vol 19. issue 4. 2018-09-11. PMID:29649138. |
flow cytometric analysis and western blot data demonstrated that luteolin induced a stronger apoptosis on undifferentiated myeloid leukemia cells with higher pttg1 protein levels than on 12-myristate 13-acetate (pma)- or all-trans-retinoic acid (atra)-differentiated cells with lower pttg1 expression. |
2018-09-11 |
2023-08-13 |
human |
| Yan Zhang, Hui Li, Xiudong Yang, Gang Jin, Yang Zhan. Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides. International journal of biological macromolecules. vol 112. 2018-09-10. PMID:29428385. |
terminal deoxynucleotidyl transferase-mediated dutp biotin nick-end labeling (tunel), immunohistochemistry, and western blot analysis showed that the tunel apoptosis cell rate, bax, cytochrome c, caspase-3, caspase-9, and apoptosis-inducing factor expression levels were obviously decreased, and the bcl-2 expression levels were obviously increased in the hippocampi of rats treated with fvp and ginsenosides. |
2018-09-10 |
2023-08-13 |
rat |
| Bin Yang, Ping Yan, Guang-Zhao Yang, Hui-Li Cao, Fei Wang, Bao L. Triptolide reduces ischemia/reperfusion injury in rats and H9C2 cells via inhibition of NF‑κB, ROS and the ERK1/2 pathway. International journal of molecular medicine. vol 41. issue 6. 2018-09-10. PMID:29512681. |
furthermore, the expression levels of proteins associated with apoptosis, peroxide and inflammation were measured using western blot analysis. |
2018-09-10 |
2023-08-13 |
rat |
| Qi Ren, Shaojun Zhao, Changjie Ren, Zhen M. Astragalus polysaccharide alleviates LPS-induced inflammation injury by regulating miR-127 in H9c2 cardiomyoblasts. International journal of immunopathology and pharmacology. vol 32. 2018-09-07. PMID:29451405. |
then, the effect of aps on cell viability and apoptosis induced by lps was determined by cck-8, flow cytometry, and western blot. |
2018-09-07 |
2023-08-13 |
Not clear |
| Jianjian Zhuang, Juxin Yin, Chaojian Xu, Ying Mu, Shaowu L. 20(S)-Ginsenoside Rh2 Induce the Apoptosis and Autophagy in U937 and K562 Cells. Nutrients. vol 10. issue 3. 2018-09-07. PMID:29518056. |
fluorescence microscopy, cck-8, quantitative realtime pcr, western blot, transmission electron microscopy (tem), and flow cytometric analysis were used to detect the occurrence of cell proliferation inhibition, apoptosis, and autophagy. |
2018-09-07 |
2023-08-13 |
Not clear |