| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qi-Fa Ye, Yi-Chuan Zhang, Xiao-Qing Peng, Zhi Long, Ying-Zi Ming, Le-Ye H. Silencing Notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through Bcl-2 and Bax. Oncology letters. vol 3. issue 4. 2021-10-21. PMID:22741011. |
silencing notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through bcl-2 and bax. |
2021-10-21 |
2023-08-12 |
Not clear |
| Xianli Wei, Lunbin Zhou, Liangyong Hu, Yaoxiong Huan. Tanshinone IIA arrests cell cycle and induces apoptosis in 786-O human renal cell carcinoma cells. Oncology letters. vol 3. issue 5. 2021-10-21. PMID:22783408. |
these results suggest that the activation of p53 and the upregulation of its target genes, including p21 and bax, may be involved in the mitochondrial apoptosis induced by tan iia in 786-o cells. |
2021-10-21 |
2023-08-12 |
human |
| Zhe Ji, Qingjiu Tang, Ruixia Hao, Jinsong Zhang, Yingjie Pa. Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3. Oncology letters. vol 2. issue 3. 2021-10-21. PMID:22866120. |
conversely, glai up-regulates the expression of the apoptosis enhancer bax gene and p53 protein. |
2021-10-21 |
2023-08-12 |
human |
| Jun Li, Haifeng Wang, Zhen Ma, Wenxing Fan, Yanfeng Li, Bingbing Han, Zhijia Zhang, Jiansong Wan. TAT-Apoptin induces apoptosis in the human bladder cancer EJ cell line and regulates Bax, Bcl-2, caspase-3 and survivin expression. Experimental and therapeutic medicine. vol 3. issue 6. 2021-10-21. PMID:22970013. |
tat-apoptin induces apoptosis in the human bladder cancer ej cell line and regulates bax, bcl-2, caspase-3 and survivin expression. |
2021-10-21 |
2023-08-12 |
human |
| Zhengguang Li, Jun Wu, Changping Wu, Jingting Jiang, Xiao Zheng, Bin Xu, Min L. Deguelin, a natural rotenoid, inhibits mouse myeloma cell growth in vitro via induction of apoptosis. Oncology letters. vol 4. issue 4. 2021-10-21. PMID:23226790. |
deguelin-induced apoptosis was characterized by the upregulation of bax, downregulation of bcl-2 and activation of caspase-3. |
2021-10-21 |
2023-08-12 |
mouse |
| Jing-Jing Li, Qi-Hua Gu, Min Li, Hua-Ping Yang, Li-Ming Cao, Cheng-Ping H. Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo. Oncology letters. vol 5. issue 1. 2021-10-21. PMID:23255902. |
role of ku70 and bax in epigallocatechin-3-gallate-induced apoptosis of a549 cells in vivo. |
2021-10-21 |
2023-08-12 |
mouse |
| Jing-Jing Li, Qi-Hua Gu, Min Li, Hua-Ping Yang, Li-Ming Cao, Cheng-Ping H. Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo. Oncology letters. vol 5. issue 1. 2021-10-21. PMID:23255902. |
this is the first study demonstrating that the induction of apoptosis by egcg may be caused by the downregulation of ku70 and that egcg disrupts the interaction between ku70 and bax in lung cancer. |
2021-10-21 |
2023-08-12 |
mouse |
| Se-Mi Oh, Jinhee Kim, Jun Lee, Jin-Mu Yi, Dal-Seok Oh, Ok-Sun Bang, No Soo Ki. Anticancer potential of an ethanol extract of Asiasari radix against HCT-116 human colon cancer cells in vitro. Oncology letters. vol 5. issue 1. 2021-10-21. PMID:23255939. |
eear-induced apoptosis was observed in parallel with activation of caspases and an increased ratio of bax (pro-apoptotic)/bcl2 (anti-apoptotic). |
2021-10-21 |
2023-08-12 |
human |
| Guo-Jun Xu, Tian-Yi Gan, Bao-Peng Tang, Zu-Heng Chen, Ailiman Mahemuti, Tao Jiang, Jian-Guo Song, Xia Guo, Yao-Dong Li, Hai-Jun Miao, Xian-Hui Zhou, Yu Zhang, Jin-Xin L. Accelerated fibrosis and apoptosis with ageing and in atrial fibrillation: Adaptive responses with maladaptive consequences. Experimental and therapeutic medicine. vol 5. issue 3. 2021-10-21. PMID:23403858. |
the aim of this study was to investigate whether abnormal expression of matrix metalloproteinase (mmp)-9/tissue inhibitors of mmps (timp)-1 and b cell lymphoma 2 (bcl-2)/bcl-2-associated x protein (bax) are correlated with the characteristic accelerated fibrosis and apoptosis during ageing and in atrial fibrillation (af). |
2021-10-21 |
2023-08-12 |
Not clear |
| Jun Pu Wang, Wan Ming Hu, Kuan Song Wang, Jun Yu, Bai Hua Luo, Chang Wu, Zhi Hong Chen, Geng Qiu Luo, Yu Wu Liu, Qin Lai Liu, Yan Xiao, Hai Yan Zhou, Xiao Jing Yang, Hai Ying Jiang, Jing He Li, Ji Fang We. Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance. Oncology letters. vol 5. issue 2. 2021-10-21. PMID:23420470. |
erk1/2 and akt phosphorylation and the expression of indicators of proliferation, growth and apoptosis (bcl-2 and bax, cyclin d1, egfr and ki-67), angiogenesis (vegf and cd34), invasion and metastasis (mmp-9, mmp-2, timp-2 and e-cadherin) were also detected by ihc. |
2021-10-21 |
2023-08-12 |
Not clear |
| Xin Zhao, Qiang Wang, Yu Qian, Liang Pan. Cassia tora L. (Jue-ming-zi) has anticancer activity in TCA8113 cells in vitro and exerts anti-metastatic effects in vivo. Oncology letters. vol 5. issue 3. 2021-10-21. PMID:23426077. |
cassia tora l. significantly induced apoptosis in cancer cells (p<0.05) by upregulating bax, caspase-3 and caspase-9, and by downregulating bcl-2. |
2021-10-21 |
2023-08-12 |
mouse |
| Teruyoshi Saito, Tamura Dai, Ryuji Asan. The hyaluronan synthesis inhibitor 4-methylumbelliferone exhibits antitumor effects against mesenchymal-like canine mammary tumor cells. Oncology letters. vol 5. issue 3. 2021-10-21. PMID:23426189. |
our experiments showed that 4-mu-induced apoptosis in cf41.mg cells involved induction of the pro-apoptotic gene bax. |
2021-10-21 |
2023-08-12 |
Not clear |
| Yali Song, Gong Zhang, Xiulan Zhu, Zhanjun Pang, Fuqi Xing, Song Qua. Overexpression of the hydatidiform mole-related gene F10 inhibits apoptosis in A549 cells through downregulation of BCL2-associated X protein and caspase-3. Oncology letters. vol 4. issue 3. 2021-10-21. PMID:23741243. |
the results of this study indicate that f10 overexpression inhibits apoptosis in a549 cells through the downregulation of the pro-apoptotic genes bax and caspase-3. |
2021-10-21 |
2023-08-12 |
human |
| Bo Yi, Dan Liu, Ming He, Qiyun Li, Tiande Liu, Jianghua Sha. Role of the ROS/AMPK signaling pathway in tetramethylpyrazine-induced apoptosis in gastric cancer cells. Oncology letters. vol 6. issue 2. 2021-10-21. PMID:24137375. |
furthermore, tmpz-induced apoptosis resulted in the sequential events beginning with the translocation of bax, the collapse of mitochondrial membrane potential (ΔΨm), the release of cytochrome |
2021-10-21 |
2023-08-12 |
Not clear |
| Yong-Tae Ahn, Ik Jae Shin, Jong-Myoung Kim, Youn Sook Kim, Chu Lee, Seong-A Ju, Won G A. Counteracting the activation of pAkt by inhibition of MEK/Erk inhibition reduces actin disruption-mediated apoptosis in PTEN-null PC3M prostate cancer cell lines. Oncology letters. vol 6. issue 5. 2021-10-21. PMID:24179529. |
induction of bax, with little effect on bcl-2 expression, indicated that actin disruption causes apoptosis through activation of bax signaling in pc3m cells. |
2021-10-21 |
2023-08-12 |
Not clear |
| F L Jiang, S Leo, X G Wang, H Li, L Y Gong, Y Kuang, X F X. Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats. Experimental and therapeutic medicine. vol 6. issue 6. 2021-10-21. PMID:24255684. |
evaluation of bcl-2, bax and p53 expression levels for apoptosis analysis was performed using western blotting. |
2021-10-21 |
2023-08-12 |
rat |
| F L Jiang, S Leo, X G Wang, H Li, L Y Gong, Y Kuang, X F X. Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats. Experimental and therapeutic medicine. vol 6. issue 6. 2021-10-21. PMID:24255684. |
it was observed that the sbp, lvmi, cardiomyocyte size and diameter, cvf, pcva and cardiomyocyte apoptosis index (bax and p53 expression) were increased significantly in group s18 compared with group s8. |
2021-10-21 |
2023-08-12 |
rat |
| F L Jiang, S Leo, X G Wang, H Li, L Y Gong, Y Kuang, X F X. Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats. Experimental and therapeutic medicine. vol 6. issue 6. 2021-10-21. PMID:24255684. |
tsn may inhibit the development of lvh and decrease the level of apoptosis in shrs, possibly via the upregulation of bcl-2 and the downregulation of bax and p53 expression. |
2021-10-21 |
2023-08-12 |
rat |
| Min Wu, Yongchang Chen, Lu Jiang, Yueying Li, Ting Lan, Ying Wang, Hai Qia. Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells. Oncology letters. vol 6. issue 6. 2021-10-21. PMID:24273605. |
egf treatment also reduced the apoptosis of the ags cells and increased the expression of the anti-apoptotic protein, bcl-2, but had no effect on the expression of the pro-apoptotic protein, bax, and did not alter the levels of caspase 9 and dff. |
2021-10-21 |
2023-08-12 |
human |
| Lihong Pi, Xiaoming Li, Qi Song, Yupeng Shen, Xiuying Lu, Bin D. Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia. Oncology letters. vol 7. issue 3. 2021-10-21. PMID:24527073. |
furthermore, knockdown of grp78 resulted in a significant increase in chop and bax expression levels and a decrease in bcl-2 expression levels with simultaneous increase in the levels of apoptosis under severely hypoxic conditions. |
2021-10-21 |
2023-08-12 |
human |