| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanling Zhang, Guang Da Yang, Qian Ya Chen, Jinlong Zeng, Yang Ca. Microrna-342 inhibits hepatocellular carcinoma cell proliferation and promotes apoptosis through the FOXP1/MYCBP Signaling Axis. Toxicology research. vol 13. issue 6. 2024-12-19. PMID:39698396. |
foxp1 could promote the proliferation of hepatocellular carcinoma cells, positively regulate the expression of c-caspase-3, bax, negatively regulate bcl-2 and inhibit apoptosis. |
2024-12-19 |
2024-12-21 |
human |
| Abdolreza Ahmadi, Fatemehsadat Hosseini, Mehdi Rostami, Mohammad Soukhtanlo. Anticancer effects of alpha-lipoic acid, a potent organosulfur compound by modulating matrix metalloproteinases and apoptotic markers in osteosarcoma MG-63 cells. The Journal of steroid biochemistry and molecular biology. 2024-12-18. PMID:39694075. |
the results demonstrated that ala significantly inhibited cell migration, induced cell cycle arrest, and promoted apoptosis by upregulating p53 and bax expression while downregulating bcl-2 levels. |
2024-12-18 |
2024-12-21 |
Not clear |
| Shuai Lu, Feiya Suo, Wenfeng Yu, Guofeng W. The therapeutic effect of different cumin essential oil fractions against gastric ulcer in rats. Journal of food science. 2024-12-17. PMID:39690115. |
the e3 fraction was selected to explore the relevant mechanism, and the results showed that e3 fraction significantly prevented the cleaved caspase-3 and bax protein levels that were ethanol-induced and resisted apoptosis induced by ethanol injury. |
2024-12-17 |
2024-12-21 |
rat |
| Haotian Wang, Lusheng Wang, Jun Xiao, Yajuan Cong, Shikun Zong, Yixuan Zhang, Jiannan Liu, Meilin Zh. Revealing the Anticancer Mechanism of Cephaibol A, a Peptaibol Isolated from Biological & pharmaceutical bulletin. vol 47. issue 12. 2024-12-15. PMID:39675961. |
mitochondrial membrane potential (ΔΨm) assay suggested that cephaibol a induced apoptosis by affecting bcl-2, bax and cytochrome c levels, thus decreasing ΔΨm and activating the caspase cascade reaction. |
2024-12-15 |
2024-12-21 |
mouse |
| Chunli Ma, Yixiao Li, Baoling Liu, Junjie Deng, Xue Gao, Huixin Zhang, Bingqiang Zhang, Qihui Zhou, Xiaoting Peng, Han Zhan. Exosomes derived from adipose mesenchymal stem cells promote corneal injury repair and inhibit the formation of scars by anti-apoptosis. Colloids and surfaces. B, Biointerfaces. vol 247. 2024-12-15. PMID:39675062. |
this effect was attributed to their ability to inhibit apoptosis of corneal stroma cells by upregulating bax and downregulating bcl2, reducing the bax/bcl2 protein expression ratio from 1 to 0.45. |
2024-12-15 |
2024-12-21 |
Not clear |
| Chunxue Jiang, Renshuai Liu, Yong Chang, Shiji Zhang, Xue Li, Zhongcheng Zhao, Mengyao Quan, Quande Wang, Hengxing Zhou, Xuben Hou, Hao Fan. Design and synthesis of novel benzoic acid derivatives as striatal-enriched protein tyrosine phosphatase (STEP) inhibitors with neuroprotective properties. European journal of medicinal chemistry. vol 283. 2024-12-10. PMID:39657460. |
compound 14b inhibited cell apoptosis by upregulating bcl-2 expression and downregulating bax and c-caspase3 expression. |
2024-12-10 |
2024-12-13 |
Not clear |
| Luyu Tang, Yongqiang Duan, Bingjie Xie, Hongyan Liu, Liqiang Zhong, Minghua Wang, Ju Liu, Chaofan Su, Xiaohui Chen, Shiyong Zhan. Effects of salinity stress on the growth performance, histological characteristics, and expression of genes related to apoptosis and immunity in channel catfish (Ictalurus punctatus). Journal of fish biology. 2024-12-09. PMID:39648824. |
quantitative polymerase chain reaction (qpcr) analysis of the expression patterns of genes related to apoptosis and immunity showed that the expression levels of caspase 3, caspase 8, inf-i, il-1β, and bax genes in the liver and intestinal tissues were higher in the experimental groups than in the control group, while the expression of bcl-2 decreased with increasing salinity in liver tissue but increased in intestinal tissue. |
2024-12-09 |
2024-12-11 |
Not clear |
| Moyan Wang, Xin Chen, Shuangyang Li, Lingxue Wang, Hongmei Tang, Yuting Pu, Dechou Zhang, Bangjiang Fang, Xue Ba. A crosstalk between autophagy and apoptosis in intracerebral hemorrhage. Frontiers in cellular neuroscience. vol 18. 2024-12-09. PMID:39650799. |
this review aims to examine the crosstalk between autophagy and apoptosis in ich by focusing on the interaction and balance of beclin 1, bax, and bcl-2. |
2024-12-09 |
2024-12-12 |
human |
| C Shi, L Zhang, W Fan, G Zho. Borneol hinders the proliferation and induces apoptosis through the suppression of reactive oxygen species-mediated JAK1 and STAT-3 signaling in human prostate cancer cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 5. 2024-12-09. PMID:39652904. |
bnl treatment enhanced apoptosis rates by observed overexpression of bcl-2-associated x protein (bax), caspase-3 and down regulation b-cell leukemia/lymphoma 2 (bcl-2) (p<0.05) expression in pc-3 cells. |
2024-12-09 |
2024-12-12 |
human |
| Yuejia Li, Yuanjing Li, Xuan Liu, Jiajie Bi, Junsheng Liu, Wen Li, Huanhuan Li, Shusong Wang, Jing M. Zinc Attenuates Bisphenol A-Induced Reproductive Toxicity in Male Mice by Inhibiting Ferroptosis and Apoptosis Through Improving Zinc Homeostasis. Biological trace element research. 2024-12-08. PMID:39645636. |
bpa down-regulated anti-apoptotic protein bcl-2, up-regulated pro-apoptotic markers bax, caspase-9, caspase-8 and caspase-3, and induced apoptosis. |
2024-12-08 |
2024-12-10 |
mouse |
| Sameh A Abdelnour, Wael A Khalil, Mahmoud A E Hassan, Ibrahim T El-Ratel, Mostafa A El-Harairy, Sherif M Dessouki, Kandil A A Atti. Protective effect of epidermal growth factor on cryopreservation of dromedary camel epididymal spermatozoa: Evidence from in vitro and in silico studies. Animal reproduction science. vol 272. 2024-12-07. PMID:39644764. |
the docking analysis indicated that egf exhibited higher binding affinity with apoptosis sperm markers, including caspase-3 and bcl-2-associated x (bax) proteins, with binding energies of -502.0 and -621.0 kcal/mol, respectively. |
2024-12-07 |
2024-12-10 |
Not clear |
| Tasneem M Salah, Mostafa A Rabie, Nesrine S El Saye. Renoprotective Effect of Berberine in Cisplatin-Induced Acute Kidney Injury: Role of Klotho and the AMPK/mTOR/ULK1/Beclin-1 Pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-12-07. PMID:39645019. |
additionally, berb reduced apoptosis by increasing bcl-2 and decreasing bax. |
2024-12-07 |
2024-12-10 |
Not clear |
| Teng Yang, Hui Fang, Dongmei Lin, Shangpeng Yang, Hongjian Luo, Lianfu Wang, Baoxue Yan. Ganoderma Lucidum polysaccharide peptide (GL-PP2): A potential therapeutic agent against sepsis-induced organ injury by modulating Nrf2/NF-κB pathways. International journal of biological macromolecules. vol 285. 2024-12-07. PMID:39643194. |
additionally, it reduces apoptosis by regulating bax, cleaved caspase-3, and bcl-2 expression. |
2024-12-07 |
2024-12-10 |
mouse |
| Timothy Su, Xiangzhu Zhu, Yong Li, Chang Yu, Xinqing Deng, Eugene Shubin, Lifang Hou, Jing Zhao, Lei Fan, Heping Zhang, Harvey J Murff, Reid M Ness, Martha J Shrubsole, Qi Da. Roles of Necroptosis, Apoptosis, and Inflammation in Colorectal Carcinogenesis: A Longitudinal Human Study. Cancer prevention research (Philadelphia, Pa.). 2024-12-05. PMID:39637028. |
we conducted quantitative analysis of biomarkers for necroptosis (transient receptor potential melastatin 7 (trpm7) and phosphorylated mixed lineage kinase-like protein (pmlkl)), inflammation (cyclooxygenase-2, cox-2), apoptosis (bax and tunel), and cell proliferation (ki67). |
2024-12-05 |
2024-12-08 |
human |
| Yanji Zhu, Guiling Xie, Fangyan Qi, ShenWei Tang, Wenlong Xu. CD73 alleviates podocytes injury in adriamycin-induced nephrotic syndrome. Tissue & cell. vol 93. 2024-12-05. PMID:39637490. |
cytokines (il-1β, il-18), apoptosis and apoposis-related protein (bax, caspase-3, desmin) levels were measured using elisa assay, flow cytometry and western blot, respectively. |
2024-12-05 |
2024-12-08 |
mouse |
| Yanji Zhu, Guiling Xie, Fangyan Qi, ShenWei Tang, Wenlong Xu. CD73 alleviates podocytes injury in adriamycin-induced nephrotic syndrome. Tissue & cell. vol 93. 2024-12-05. PMID:39637490. |
cd73, the cytokines of il-1β and il-18, apoptosis rate and the expression of bax, caspase-3 and desmin were significantly increased in adr group compared with the control group. |
2024-12-05 |
2024-12-08 |
mouse |
| Yanji Zhu, Guiling Xie, Fangyan Qi, ShenWei Tang, Wenlong Xu. CD73 alleviates podocytes injury in adriamycin-induced nephrotic syndrome. Tissue & cell. vol 93. 2024-12-05. PMID:39637490. |
however, in comparsion with the adr group, the cytokines of il-1β and il-18, apoptosis rate and the expression of bax, caspase-3 and desmin protein were remarkably lowered in the adr+cd73 shrna group. |
2024-12-05 |
2024-12-08 |
mouse |
| Shengliang Cao, Yanlan Li, Lele Chen, Xiaojing Lei, Xiujuan Feng, Yubao L. HSP60 inhibits DF-1 apoptosis through its mitochondrial signal peptide. Poultry science. vol 104. issue 1. 2024-12-05. PMID:39637657. |
the results showed that compared with the control df-1 cells, hsp60 knockdout cells indicated significantly increased apoptosis rates, decreased bax expression, and enhanced caspase 3 expression. |
2024-12-05 |
2024-12-08 |
Not clear |
| Shengliang Cao, Yanlan Li, Lele Chen, Xiaojing Lei, Xiujuan Feng, Yubao L. HSP60 inhibits DF-1 apoptosis through its mitochondrial signal peptide. Poultry science. vol 104. issue 1. 2024-12-05. PMID:39637657. |
this suggests that the hsp60 knockout induces apoptosis by up-regulating caspase 3 and down-regulating bax expression. |
2024-12-05 |
2024-12-08 |
Not clear |
| Shengliang Cao, Yanlan Li, Lele Chen, Xiaojing Lei, Xiujuan Feng, Yubao L. HSP60 inhibits DF-1 apoptosis through its mitochondrial signal peptide. Poultry science. vol 104. issue 1. 2024-12-05. PMID:39637657. |
in addition, the transfection of hsp60 mutant protein (tb) into df-1-hsp60-ko cells and induction with bardoxolone methyi significantly increased the apoptosis rates and reduced cell viability compared to the wild-type hsp60 group, inducing differential changes in genes such as bax, bak, and bcl-2. |
2024-12-05 |
2024-12-08 |
Not clear |