| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Wen Li, Xiao-Hua Wang, Qin Nin, Xiao-Ping Lu. [Excessive copper induces hepatocyte apoptosis and affects Bax and Bcl-2 expression in rat liver]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 10. issue 1. 2008-06-05. PMID:18289470. |
[excessive copper induces hepatocyte apoptosis and affects bax and bcl-2 expression in rat liver]. |
2008-06-05 |
2023-08-12 |
rat |
| Yu-Wen Li, Xiao-Hua Wang, Qin Nin, Xiao-Ping Lu. [Excessive copper induces hepatocyte apoptosis and affects Bax and Bcl-2 expression in rat liver]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 10. issue 1. 2008-06-05. PMID:18289470. |
to establish a hepatolenticular degeneration rat model with excessive copper, and investigate the effects of excessive copper deposits in the liver on hepatocyte apoptosis and bax and bcl-2 expression. |
2008-06-05 |
2023-08-12 |
rat |
| Vitaliy Kaminskyy, Oleksandr Kulachkovskyy, Rostyslav Stoik. A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids. Toxicology letters. vol 177. issue 3. 2008-06-05. PMID:18325696. |
during apoptosis induction by sanguinarine and chelerythrine, reactive oxygen species (ros) was rapidly generated and deltapsi(mt) dissipated, while bax, bcl-2 and bcl-x((l/s)) proteins' content in the mitochondrial fraction did not change significantly. |
2008-06-05 |
2023-08-12 |
human |
| W Zhang, M Konopleva, V R Ruvolo, T McQueen, R L Evans, W G Bornmann, J McCubrey, J Cortes, M Andreef. Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway. Leukemia. vol 22. issue 4. 2008-06-04. PMID:18200035. |
mechanistically, treatment with sorafenib resulted in upregulation of proapoptotic bim, accompanied by an increase in bad, bax and bak protein levels and decreased mcl-1, x-linked inhibitor of apoptosis and surviving levels, which mainly led to the activation of the intrinsic apoptotic pathway. |
2008-06-04 |
2023-08-12 |
Not clear |
| Na Li, Lin Zheng, Peihui Lin, David Danielpour, Zui Pan, Jianjie M. Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells. Journal of cellular physiology. vol 216. issue 1. 2008-06-04. PMID:18247359. |
this study investigates the functional interaction between bax and soce in the apoptosis signaling cascade in prostate cancer. |
2008-06-04 |
2023-08-12 |
Not clear |
| Na Li, Lin Zheng, Peihui Lin, David Danielpour, Zui Pan, Jianjie M. Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells. Journal of cellular physiology. vol 216. issue 1. 2008-06-04. PMID:18247359. |
our previous findings show that nrp-154, an androgen-independent prostate cancer cell line, could sustain overexpression of exogenous bax without undergoing apoptosis. |
2008-06-04 |
2023-08-12 |
Not clear |
| Na Li, Lin Zheng, Peihui Lin, David Danielpour, Zui Pan, Jianjie M. Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells. Journal of cellular physiology. vol 216. issue 1. 2008-06-04. PMID:18247359. |
while reduced soce may represent an adaptive mechanism for cell survival, increased levels of bax in the latent state enhances the sensitivity of nrp-154 cells to tgf-beta and thapsigargin-induced apoptosis. |
2008-06-04 |
2023-08-12 |
Not clear |
| Na Li, Lin Zheng, Peihui Lin, David Danielpour, Zui Pan, Jianjie M. Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells. Journal of cellular physiology. vol 216. issue 1. 2008-06-04. PMID:18247359. |
our results demonstrate a functional interaction between bax and soce in apoptosis of prostate cancer, and support the concept that improving this interaction has therapeutic implications for prostate cancer. |
2008-06-04 |
2023-08-12 |
Not clear |
| Lin Yang, Yongyu Mei, Qifeng Xie, Xiaoyan Han, Fucheng Zhang, Lin Gu, Yufeng Zhang, Youming Chen, Gang Li, Zhiliang Ga. Acidification induces Bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis. Cellular & molecular biology letters. vol 13. issue 1. 2008-06-03. PMID:17965970. |
acidification induces bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis. |
2008-06-03 |
2023-08-12 |
Not clear |
| Lin Yang, Yongyu Mei, Qifeng Xie, Xiaoyan Han, Fucheng Zhang, Lin Gu, Yufeng Zhang, Youming Chen, Gang Li, Zhiliang Ga. Acidification induces Bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis. Cellular & molecular biology letters. vol 13. issue 1. 2008-06-03. PMID:17965970. |
it has been suggested that bax translocation to the mitochondria is related to apoptosis, and that cytosol acidification contributes to apoptosis events. |
2008-06-03 |
2023-08-12 |
Not clear |
| Lin Yang, Yongyu Mei, Qifeng Xie, Xiaoyan Han, Fucheng Zhang, Lin Gu, Yufeng Zhang, Youming Chen, Gang Li, Zhiliang Ga. Acidification induces Bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis. Cellular & molecular biology letters. vol 13. issue 1. 2008-06-03. PMID:17965970. |
we investigated the effect of acidification on bax translocation and on ultraviolet (uv) light-induced apoptosis. |
2008-06-03 |
2023-08-12 |
Not clear |
| Lin Yang, Yongyu Mei, Qifeng Xie, Xiaoyan Han, Fucheng Zhang, Lin Gu, Yufeng Zhang, Youming Chen, Gang Li, Zhiliang Ga. Acidification induces Bax translocation to the mitochondria and promotes ultraviolet light-induced apoptosis. Cellular & molecular biology letters. vol 13. issue 1. 2008-06-03. PMID:17965970. |
our results indicated that acidification induces bax translocation from the cytosol to the mitochondria, and promotes uv light-mediated apoptosis. |
2008-06-03 |
2023-08-12 |
Not clear |
| N Hajji, K Wallenborg, P Vlachos, U Nyman, O Hermanson, B Josep. Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. Oncogene. vol 27. issue 22. 2008-06-03. PMID:18071312. |
co-treatment, but not single treatment, with vp16 and tsa induced apoptosis in a caspase-dependent manner accompanied by a crucial decrease in bcl-xl expression allowing bax activation and subsequent initiation of the apoptosis inducing factor (aif)-dependent death pathway. |
2008-06-03 |
2023-08-12 |
Not clear |
| Uma Sinha-Datta, John M Taylor, Megan Brown, Christophe Nico. Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt. Apoptosis : an international journal on programmed cell death. vol 13. issue 1. 2008-06-02. PMID:17952603. |
treatment with celecoxib was associated with activation of bax, decreased expression of mcl-1, loss of the mitochondrial membrane potential and caspase-9-dependent apoptosis. |
2008-06-02 |
2023-08-12 |
human |
| Christian Cahlin, Christina Lönnroth, Annette Arvidsson, Svante Nordgren, Kent Lundhol. Growth associated proteins in tumor cells and stroma related to disease progression of colon cancer accounting for tumor tissue PGE2 content. International journal of oncology. vol 32. issue 4. 2008-06-02. PMID:18360718. |
connections among specific proteins (bax, bcl-2, bfgf, cox-1, cox-2, e-cad, p15, p53, pcna, tgfbeta3, tunel, vwf) in control of cell proliferation, apoptosis, cell adhesion, tumor vascularity and pge2 content were evaluated in colon cancer as related to disease progression and survival. |
2008-06-02 |
2023-08-12 |
Not clear |
| Jesús M Golbano, Pilar Lóppez-Aparicio, María N Recio, Miguel A Pérez-Albarsan. Finasteride induces apoptosis via Bcl-2, Bcl-xL, Bax and caspase-3 proteins in LNCaP human prostate cancer cell line. International journal of oncology. vol 32. issue 4. 2008-06-02. PMID:18360719. |
finasteride induces apoptosis via bcl-2, bcl-xl, bax and caspase-3 proteins in lncap human prostate cancer cell line. |
2008-06-02 |
2023-08-12 |
human |
| Francisco Carvallo-Chaigneau, Cristina Trejo-Solís, Celedonio Gómez-Ruiz, Ernesto Rodríguez-Aguilera, Lucía Macías-Rosales, Edith Cortés-Barberena, Carlos Cedillo-Peláez, Isabel Gracia-Mora, Lena Ruiz-Azuara, Vicente Madrid-Marina, Fernando Constantino-Casa. Casiopeina III-ia induces apoptosis in HCT-15 cells in vitro through caspase-dependent mechanisms and has antitumor effect in vivo. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 21. issue 1. 2008-05-30. PMID:17390215. |
apoptosis was related to bax increasing levels, suggesting a caspase-dependent mechanism of death, as verified by nucleosomal fragmentation of dna. |
2008-05-30 |
2023-08-12 |
mouse |
| S Heitz, V Gautheron, Y Lutz, J-L Rodeau, H S Zanjani, I Sugihara, G Bombarde, F Richard, J-P Fuchs, M W Vogel, J Mariani, Y Baill. BCL-2 counteracts Doppel-induced apoptosis of prion-protein-deficient Purkinje cells in the Ngsk Prnp(0/0) mouse. Developmental neurobiology. vol 68. issue 3. 2008-05-30. PMID:18085563. |
the pro-apoptotic factor bax has recently been shown to contribute to purkinje cell (pc) apoptosis induced by the neurotoxic prion-like protein doppel (dpl) in the prion-protein-deficient ngsk prnp(0/0) (np(0/0)) mouse. |
2008-05-30 |
2023-08-12 |
mouse |
| Marc Germain, Jocelyn Milburn, Vincent Duroni. MCL-1 inhibits BAX in the absence of MCL-1/BAX Interaction. The Journal of biological chemistry. vol 283. issue 10. 2008-05-30. PMID:18089567. |
the pro-apoptotic bcl-2 homologues bax and bak are activated following the induction of apoptosis and induce cytochrome c release from mitochondria. |
2008-05-30 |
2023-08-12 |
Not clear |
| Dayong Zhai, Chaofang Jin, Ziwei Huang, Arnold C Satterthwait, John C Ree. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. The Journal of biological chemistry. vol 283. issue 15. 2008-05-28. PMID:18178565. |
in this report, we compared the ability of the six human anti-apoptotic bcl-2 family members to suppress apoptosis induced by overexpression of bax or bak, correlating findings with protein interactions measured by three different methods: co-immunoprecipitation, glutathione s-transferase pulldown, and fluorescence polarization assays employing synthetic bh3 peptides from bax and bak. |
2008-05-28 |
2023-08-12 |
human |