| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sumiti Kalia, M P Bansa. Diethyl maleate-induced oxidative stress leads to testicular germ cell apoptosis involving Bax and Bcl-2. Journal of biochemical and molecular toxicology. vol 22. issue 6. 2009-04-08. PMID:19110998. |
diethyl maleate-induced oxidative stress leads to testicular germ cell apoptosis involving bax and bcl-2. |
2009-04-08 |
2023-08-12 |
mouse |
| Yan Cheng, Feng Qiu, Yuan-Chao Ye, Zhao-Ming Guo, Shin-Ichi Tashiro, Satoshi Onodera, Takashi Ikejim. Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cells. The FEBS journal. vol 276. issue 5. 2009-04-08. PMID:19187231. |
we showed that reactive oxygen species triggered apoptosis by bax translocation, cytochrome c release and extracellular signal-regulated kinase activation. |
2009-04-08 |
2023-08-12 |
Not clear |
| Sanchita P Ghosh, Michael W Perkins, Kevin Hieber, Shilpa Kulkarni, Tzu-Cheg Kao, E Premkumar Reddy, M V Ramana Reddy, Manoj Maniar, Thomas Seed, K Sree Kuma. Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms. Radiation research. vol 171. issue 2. 2009-04-07. PMID:19267542. |
western blot analyses indicated that the radiation protection provided by ex-rad resulted in reduced levels of pro-apoptosis proteins such as p53 as well as its downstream regulators p21, bax, c-abl and p73, indicating that ex-rad could rescue cells from ionizing radiation-induced p53-dependent apoptosis. |
2009-04-07 |
2023-08-12 |
mouse |
| Marco Coassin, Alessandro Lambiase, Valentina Sposato, Alessandra Micera, Stefano Bonini, Luigi Alo. Retinal p75 and bax overexpression is associated with retinal ganglion cells apoptosis in a rat model of glaucoma. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. vol 246. issue 12. 2009-04-03. PMID:18751719. |
retinal p75 and bax overexpression is associated with retinal ganglion cells apoptosis in a rat model of glaucoma. |
2009-04-03 |
2023-08-12 |
rat |
| E Szegezdi, K Reed Herbert, E T Kavanagh, A Samali, A M Gorma. Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim. Journal of cellular and molecular medicine. vol 12. issue 6A. 2009-04-02. PMID:18266951. |
ngf pre-treatment inhibited translocation of bax to the mitochondria, loss of mitochondrial transmembrane potential, cytochrome c release, activation of caspases (-3, -7 and -9) and apoptosis induction by tg. |
2009-04-02 |
2023-08-12 |
Not clear |
| E Szegezdi, K Reed Herbert, E T Kavanagh, A Samali, A M Gorma. Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim. Journal of cellular and molecular medicine. vol 12. issue 6A. 2009-04-02. PMID:18266951. |
these data indicate that ngf-mediated protection against er stress-induced apoptosis occurs at the level of the mitochondria by regulating induction and activation of bim and mitochondrial translocation of bax. |
2009-04-02 |
2023-08-12 |
Not clear |
| Tiziana Genovese, Emanuela Esposito, Emanuela Mazzon, Rosanna Di Paola, Rocco Caminiti, Placido Bramanti, Alessandro Cappelani, Salvatore Cuzzocre. Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice. Journal of neurochemistry. vol 108. issue 6. 2009-04-02. PMID:19183262. |
il-10 wild-type mice developed severe spinal cord damage characterized by oedema, tissue damage and apoptosis (measured by annexin-v, terminal deoxynucleotidyltransferase-mediated utp end labeling staining, bax, bcl-2, and fas-l expression). |
2009-04-02 |
2023-08-12 |
mouse |
| Ghazaleh Aram, James J Potter, Xiaopu Liu, Lan Wang, Michael S Torbenson, Esteban Meze. Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration. Hepatology (Baltimore, Md.). vol 49. issue 3. 2009-04-01. PMID:19072832. |
by contrast, more hepatocyte apoptosis was found after ccl(4) in the wt than in the gp91(phox(-/-) ) mice, which was associated with changes in components of the mitochondrial pathway of apoptosis, namely, an increase in the pro-apoptotic bax protein in the wt, but not in the gp91(phox(-/-) ) mice and also a lower cytosolic cytochrome c in the gp91(phox(-/-) ) mice. |
2009-04-01 |
2023-08-12 |
mouse |
| Aitor Etxebarria, Oihana Terrones, Hirohito Yamaguchi, Ane Landajuela, Olatz Landeta, Bruno Antonsson, Hong-Gang Wang, Gorka Basañe. Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangements. The Journal of biological chemistry. vol 284. issue 7. 2009-03-31. PMID:19074440. |
here, we demonstrate that the stimulatory effect of bif-1 on bax-driven momp and on bax conformational activation observed in intact cells during apoptosis can be recapitulated in a simplified system consisting of purified proteins and mom-like liposomes. |
2009-03-31 |
2023-08-12 |
Not clear |
| Dita Královcová, Marcela Pejchalová, Emil Rudolf, Miroslav Cervink. Quantitative analysis of expression level of BCL2 and BAX genes in Hep-2 and HL-60 cells after treatment with etoposide. Acta medica (Hradec Kralove). vol 51. issue 3. 2009-03-31. PMID:19271688. |
the aim of the present research was to investigate the expression of the apoptosis related genes bcl2 and bax in hep-2 and hl60 cells. |
2009-03-31 |
2023-08-12 |
Not clear |
| Bo Liu, Yan Cheng, He-Jiao Bian, Jin-Ku Ba. Molecular mechanisms of Polygonatum cyrtonema lectin-induced apoptosis and autophagy in cancer cells. Autophagy. vol 5. issue 2. 2009-03-30. PMID:19139634. |
the mechanism of apoptosis following treatment with pcl involved regulation of bax, bcl-x(l) and bcl-2 proteins, which then caused collapse of the mitochondrial membrane potential, leading to cytochrome c release and caspase activation. |
2009-03-30 |
2023-08-12 |
human |
| Chun Yu Niu, Zi Gang Zhao, Rui Hua Chen, Ji Cheng Li, Jing Zhang, Yan Kai Liu, Yu Ping Zhan. [Effects of shock lymph inducing the mesentery micro-lymphatic endothelial cells apoptosis of rats]. Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology. vol 40. issue 4. 2009-03-27. PMID:17966460. |
the expressions of relative genes of apoptosis such as fas, fasl, bcl-2 and bax of mmlecs were detected by rt-pcr. |
2009-03-27 |
2023-08-12 |
rat |
| Dong Xiao, Yan Zeng, Eun-Ryeong Hahm, Young-Ae Kim, Suresh Ramalingam, Shivendra V Sing. Diallyl trisulfide selectively causes Bax- and Bak-mediated apoptosis in human lung cancer cells. Environmental and molecular mutagenesis. vol 50. issue 3. 2009-03-27. PMID:18800351. |
the dats-induced apoptosis correlated with induction of pro-apoptotic proteins bax, bak and bid, and a decrease in the expression of anti-apoptotic proteins bcl-2 and bcl-xl in lung cancer cells but not in beas-2b. |
2009-03-27 |
2023-08-12 |
human |
| Dong Xiao, Yan Zeng, Eun-Ryeong Hahm, Young-Ae Kim, Suresh Ramalingam, Shivendra V Sing. Diallyl trisulfide selectively causes Bax- and Bak-mediated apoptosis in human lung cancer cells. Environmental and molecular mutagenesis. vol 50. issue 3. 2009-03-27. PMID:18800351. |
in conclusion, the present study indicates that bax and bak proteins are critical targets of dats-induced apoptosis in human lung cancer cells. |
2009-03-27 |
2023-08-12 |
human |
| Xin-Jiang Wu, Ying Hu, Evelyn Lamy, Volker Mersch-Sunderman. Apoptosis induction in human lung adenocarcinoma cells by oil-soluble allyl sulfides: triggers, pathways, and modulators. Environmental and molecular mutagenesis. vol 50. issue 3. 2009-03-27. PMID:19197990. |
in our test series, up-regulation of extracellular signal-regulated protein kinase (erk) was dispensable for apoptosis induction; das, dads, or dats did not modify expression of mapk p38, bax, and bcl-xl. |
2009-03-27 |
2023-08-12 |
human |
| Marta Lloret, Pedro Carlos Lara, Elisa Bordón, Fausto Fontes, Agustin Rey, Beatriz Pinar, Orlando Falcó. Major vault protein may affect nonhomologous end-joining repair and apoptosis through Ku70/80 and bax downregulation in cervical carcinoma tumors. International journal of radiation oncology, biology, physics. vol 73. issue 4. 2009-03-25. PMID:19251084. |
major vault protein may affect nonhomologous end-joining repair and apoptosis through ku70/80 and bax downregulation in cervical carcinoma tumors. |
2009-03-25 |
2023-08-12 |
Not clear |
| Young-Pil Yun, Joo Yong Lee, Eun-Kyung Ahn, Kweon Haeng Lee, Hyoung Kyu Yoon, Young Li. Diesel exhaust particles induce apoptosis via p53 and Mdm2 in J774A.1 macrophage cell line. Toxicology in vitro : an international journal published in association with BIBRA. vol 23. issue 1. 2009-03-24. PMID:18940243. |
taken together, the findings of the present study suggest that dep trigger apoptosis in j774a.1 macrophage cells via the activation of p53, followed by bax. |
2009-03-24 |
2023-08-12 |
Not clear |
| Ning Wang, Li-Jian Tang, Guo-Qi Zhu, Dai-Yin Peng, Lei Wang, Fa-Neng Sun, Qing-Lin L. Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cells. Journal of Asian natural products research. vol 10. issue 11-12. 2009-03-24. PMID:19031258. |
apoptosis induced by baicalin involving up-regulation of p53 and bax in mcf-7 cells. |
2009-03-24 |
2023-08-12 |
human |
| Ning Wang, Li-Jian Tang, Guo-Qi Zhu, Dai-Yin Peng, Lei Wang, Fa-Neng Sun, Qing-Lin L. Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cells. Journal of Asian natural products research. vol 10. issue 11-12. 2009-03-24. PMID:19031258. |
in the present study, we examined the potential roles of p53, bax, and bcl-2 in baicalin-triggered apoptosis in mcf-7 cells, a cell line derived from human breast cancer. |
2009-03-24 |
2023-08-12 |
human |
| Ning Wang, Li-Jian Tang, Guo-Qi Zhu, Dai-Yin Peng, Lei Wang, Fa-Neng Sun, Qing-Lin L. Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cells. Journal of Asian natural products research. vol 10. issue 11-12. 2009-03-24. PMID:19031258. |
collectively, the data demonstrated that baicalin-induced apoptotic cell death in the breast cancer cells involves the up-regulation of proapoptotic p53 and bax, implying potential crucial roles of bax and p53 in the baicalin-induced apoptosis. |
2009-03-24 |
2023-08-12 |
human |