| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carolina D Garciarena, Claudia I Caldiz, Enrique L Portiansky, Gladys E Chiappe de Cingolani, Irene L Enni. Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart. Journal of applied physiology (Bethesda, Md. : 1985). vol 106. issue 4. 2009-05-29. PMID:19179646. |
apoptosis was assessed by tunel staining, the expression of bcl-2, bax, and activation of caspase-3 and parp-1 by immunoblot. |
2009-05-29 |
2023-08-12 |
rat |
| C Grandela, M F Pera, S M Grimmond, G Kolle, E J Wolvetan. p53 is required for etoposide-induced apoptosis of human embryonic stem cells. Stem cell research. vol 1. issue 2. 2009-05-27. PMID:19383392. |
etoposide treatment results in a rapid and extensive induction of apoptosis and leads to a further increase in p53 and puma expression as well as bax processing. |
2009-05-27 |
2023-08-12 |
human |
| C Grandela, M F Pera, S M Grimmond, G Kolle, E J Wolvetan. p53 is required for etoposide-induced apoptosis of human embryonic stem cells. Stem cell research. vol 1. issue 2. 2009-05-27. PMID:19383392. |
hesc stably transduced with p53 shrna display 80% reduction of endogenous p53 and exhibit an 80% reduction in etoposide-induced apoptosis accompanied by constitutive downregulation of bax and an attenuated upregulation of puma. |
2009-05-27 |
2023-08-12 |
human |
| Guo-Hua Zheng, Hui-Qing L. [Effects of garlic oil combined with resveratrol on inducting of apoptosis and expression of Fas, bcl-2 and bax in human gastric cancer cell line]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 42. issue 1. 2009-05-26. PMID:18512326. |
[effects of garlic oil combined with resveratrol on inducting of apoptosis and expression of fas, bcl-2 and bax in human gastric cancer cell line]. |
2009-05-26 |
2023-08-12 |
human |
| Guo-Hua Zheng, Hui-Qing L. [Effects of garlic oil combined with resveratrol on inducting of apoptosis and expression of Fas, bcl-2 and bax in human gastric cancer cell line]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 42. issue 1. 2009-05-26. PMID:18512326. |
to explore the effects of garlic oil combined with resveratrol on the apoptosis and expression of fas, bcl-2 and bax in human gastric cancer cell line mgc-803. |
2009-05-26 |
2023-08-12 |
human |
| Alessandra Fontanini, Carmela Foti, Harish Potu, Enrico Crivellato, Roberta Maestro, Paolo Bernardi, Francesca Demarchi, Claudio Brancolin. The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB. The Journal of biological chemistry. vol 284. issue 13. 2009-05-26. PMID:19139105. |
we have discovered that (i) both inhibitors induce apoptosis in a bax and bak-dependent manner, (ii) both inhibitors elicit autophagy in wt and dko cells, and (iii) only g5 can kill apoptosis-resistant dko cells by activating a necrotic response. |
2009-05-26 |
2023-08-12 |
mouse |
| Yeon-Ji Jeong, Mi-Kyeong Kim, Hye-Jin Song, Eun-Ju Kang, Sun-A Ock, B Mohana Kumar, S Balasubramanian, Gyu-Jin Rh. Effect of alpha-tocopherol supplementation during boar semen cryopreservation on sperm characteristics and expression of apoptosis related genes. Cryobiology. vol 58. issue 2. 2009-05-26. PMID:19141297. |
the present study evaluated the influence of alpha-tocopherol supplementation at various concentrations in the boar semen extender during cryopreservation on post-thawed sperm motility characteristics (total sperm motility, mot; local motility, lcm; curvilinear velocity, vcl; straight linear velocity, vsl; and average path velocity, vap), sperm qualities (viability, acrosomal integrity and apoptosis), expression of stress protein (hsp70), and the expression of pro-apoptotic (bax and bak) and anti-apoptotic (bcl-2l and bcl-xl) genes. |
2009-05-26 |
2023-08-12 |
Not clear |
| A M Jabbour, J E Heraud, C P Daunt, T Kaufmann, J Sandow, L A O'Reilly, B A Callus, A Lopez, A Strasser, D L Vaux, P G Eker. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation. vol 16. issue 4. 2009-05-22. PMID:19079139. |
puma indirectly activates bax to cause apoptosis in the absence of bid or bim. |
2009-05-22 |
2023-08-12 |
Not clear |
| A M Jabbour, J E Heraud, C P Daunt, T Kaufmann, J Sandow, L A O'Reilly, B A Callus, A Lopez, A Strasser, D L Vaux, P G Eker. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation. vol 16. issue 4. 2009-05-22. PMID:19079139. |
pro-apoptotic bcl-2 family members bax and bak are essential for apoptosis triggered by interleukin-3 (il-3) withdrawal in myeloid cells. |
2009-05-22 |
2023-08-12 |
Not clear |
| A M Jabbour, J E Heraud, C P Daunt, T Kaufmann, J Sandow, L A O'Reilly, B A Callus, A Lopez, A Strasser, D L Vaux, P G Eker. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation. vol 16. issue 4. 2009-05-22. PMID:19079139. |
puma expression resulted in activation of bax, but puma killing was not dependent on bax or bak alone as puma readily induced apoptosis in cells lacking either of these proteins, but could not kill cells deficient for both. |
2009-05-22 |
2023-08-12 |
Not clear |
| A R Stankiewicz, A M Livingstone, N Mohseni, D D Mosse. Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70. Cell death and differentiation. vol 16. issue 4. 2009-05-22. PMID:19148187. |
heat directly affects bax activity in vitro; however, antiapoptotic bcl-2 family proteins, such as bcl-xl, can suppress this activation, suggesting that a second heat-sensitive step must be breached before apoptosis ensues in cells exposed to hyperthermia. |
2009-05-22 |
2023-08-12 |
Not clear |
| Tiziana Genovese, Marta Menegazzi, Emanuela Mazzon, Concetta Crisafulli, Rosanna Di Paola, Martina Dal Bosco, Zhenzhen Zou, Hisanori Suzuki, Salvatore Cuzzocre. Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice. Shock (Augusta, Ga.). vol 31. issue 4. 2009-05-20. PMID:18665052. |
spinal cord injury in mice resulted in severe trauma characterized by edema, tissue damage, and apoptosis (measured by terminal deoxynucleotidyltransferase-mediated dutp-biotin end labeling staining, bax, and bcl-2 expression). |
2009-05-20 |
2023-08-12 |
mouse |
| Tiziana Genovese, Marta Menegazzi, Emanuela Mazzon, Concetta Crisafulli, Rosanna Di Paola, Martina Dal Bosco, Zhenzhen Zou, Hisanori Suzuki, Salvatore Cuzzocre. Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice. Shock (Augusta, Ga.). vol 31. issue 4. 2009-05-20. PMID:18665052. |
in contrast, the degree of (1) spinal cord inflammation and tissue injury (histological score), (2) nitrotyrosine and poly(adenosine diphosphate [adp] ribose) formation, (3) inos expression, (4) nuclear factor-kappab activation, and (5) apoptosis (terminal deoxynucleotidyltransferase-mediated dutp-biotin end labeling, bax, and bcl-2) was markedly reduced in spinal cord tissue obtained from mice treated with glycyrrhizin extract (10 mg/kg, i.p., 30 min before and 1 and 6 h after sci). |
2009-05-20 |
2023-08-12 |
mouse |
| Kee Hwan Yoo, Hyung Eun Yim, Gi Young Jang, In Sun Bae, Byung Min Choi, Young Sook Hong, Joo Won Le. Endothelin A receptor blockade influences apoptosis and cellular proliferation in the developing rat kidney. Journal of Korean medical science. vol 24. issue 1. 2009-05-20. PMID:19270827. |
in conclusion, inhibition of endogenous endothelins impairs renal growth, in which decreased cellular proliferation, increased apoptosis and decreased expressions of renal bcl-x(l) and bax are possibly implicated. |
2009-05-20 |
2023-08-12 |
rat |
| Chien-Chih Chiu, Kuei-Li Lin, Ching-Ming Chien, Long-Sen Chang, Shinne-Ren Li. Effects of cardiotoxin III on NF-kappaB function, proliferation, and apoptosis in human breast MCF-7 cancer cells. Oncology research. vol 17. issue 7. 2009-05-20. PMID:19408576. |
ctx iii-induced apoptosis in human breast mcf-7 cancer cells was confirmed by sub-g1 formation, phosphatidylserine (ps) externalization, and poly (adp-ribose) polymerase (parp) cleavage with an ic50 of 2 microg/ml at 48 h. effects of ctx iii on proliferation and apoptosis correlated with upregulation of bax, and downregulation of bcl-xl, bcl-2, and xiap, with no appreciable alteration on the protein levels of bid, bim, and survivin. |
2009-05-20 |
2023-08-12 |
human |
| P V Ravindra, Ashok K Tiwari, Barkha Ratta, Uttara Chaturvedi, Sudesh Kumar Palia, R S Chauha. Newcastle disease virus-induced cytopathic effect in infected cells is caused by apoptosis. Virus research. vol 141. issue 1. 2009-05-19. PMID:19152817. |
based on these results, it was concluded that cpe in ndv-infected cells was caused by to the induction of apoptosis with the involvement of p53 and the bax, dependent apoptotic pathways. |
2009-05-19 |
2023-08-12 |
Not clear |
| Sujit K Bhutia, Sanjaya K Mallick, Swatilekha Maiti, Tapas K Mait. Inhibitory effect of Abrus abrin-derived peptide fraction against Dalton's lymphoma ascites model. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 16. issue 4. 2009-05-18. PMID:18706794. |
further, the western blotting showed that apoptosis was mediated by the reduction in the ratio of bcl-2 and bax protein expression, and activation of caspase-3 through the release of cytochrome c in dl cells. |
2009-05-18 |
2023-08-12 |
mouse |
| Anthony Leta. Puma strikes Bax. The Journal of cell biology. vol 185. issue 2. 2009-05-15. PMID:19380876. |
the commitment to programmed cell death via apoptosis is largely made upon activation of the proapoptotic mitochondrial proteins bax or bak. |
2009-05-15 |
2023-08-12 |
Not clear |
| Anthony Leta. Puma strikes Bax. The Journal of cell biology. vol 185. issue 2. 2009-05-15. PMID:19380876. |
185:279-290) provide evidence that the p53 up-regulated modulator of apoptosis (puma) protein can directly activate bax. |
2009-05-15 |
2023-08-12 |
Not clear |
| Tristan Gallenne, Fabien Gautier, Lisa Oliver, Eric Hervouet, Belinda Noël, John A Hickman, Olivier Geneste, Pierre-François Cartron, François M Vallette, Stephen Manon, Philippe Jui. Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members. The Journal of cell biology. vol 185. issue 2. 2009-05-15. PMID:19380879. |
it is still unclear whether the bh3-only protein puma (p53 up-regulated modulator of apoptosis) can prime cells to death and render antiapoptotic bh3-binding bcl-2 homologues necessary for survival through its ability to directly interact with proapoptotic bax and activate it. |
2009-05-15 |
2023-08-12 |
human |