| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bingshe Han, Yun Ren, Liying Guan, Wei Wei, Fangyuan Hua, Yang Yang, Tao Yang, Tingming Cao, Hua Dong, Huazhen Pan, Caimin X. Sodium selenite induces apoptosis in acute promyelocytic leukemia-derived NB4 cells through mitochondria-dependent pathway. Oncology research. vol 17. issue 8. 2009-07-15. PMID:19544974. |
our findings here demonstrate that sodium selenite can induce apoptosis in nb4 cells through a mechanism involving ros, activation of proapoptotic proteins bad and bax, deltapsim disruption, release of cytochrome c, and consequent initiation of caspase cascade. |
2009-07-15 |
2023-08-12 |
Not clear |
| Maura Farinacci, Monica Colitti, Bruno Stefano. Modulation of ovine neutrophil function and apoptosis by standardized extracts of Echinacea angustifolia, Butea frondosa and Curcuma longa. Veterinary immunology and immunopathology. vol 128. issue 4. 2009-07-14. PMID:19128841. |
spontaneous apoptosis strongly increased in ovine neutrophils cultured for 22h (t22), accompanied by an upregulation of il8 and a decreased bcl2a1:bax ratio. |
2009-07-14 |
2023-08-12 |
Not clear |
| S K Chaube, Anima Tripathi, Sabana Khatun, S K Mishra, P V Prasad, T G Shrivasta. Extracellular calcium protects against verapamil-induced metaphase-II arrest and initiation of apoptosis in aged rat eggs. Cell biology international. vol 33. issue 3. 2009-07-13. PMID:19385030. |
extracellular ca(2+) (1.80 mm) reduced intracellular h2o2 level, bax protein expression, caspase-3 activity, dna fragmentation and protected against 50 microm, but not higher concentrations of > or =100 microm in verapamil-induced egg apoptosis. |
2009-07-13 |
2023-08-12 |
rat |
| Yong-xing Tan, Di-fen Wang, Xue-mei Li, Xing-min Li. [Effects of nerve growth factor pretreatment on apoptosis of neurons and expression of Bcl-2, Bax protein in brain tissue following cerebral ischemia/reperfusion injury in gerbils]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. vol 19. issue 6. 2009-07-09. PMID:17577445. |
[effects of nerve growth factor pretreatment on apoptosis of neurons and expression of bcl-2, bax protein in brain tissue following cerebral ischemia/reperfusion injury in gerbils]. |
2009-07-09 |
2023-08-12 |
Not clear |
| Yong-xing Tan, Di-fen Wang, Xue-mei Li, Xing-min Li. [Effects of nerve growth factor pretreatment on apoptosis of neurons and expression of Bcl-2, Bax protein in brain tissue following cerebral ischemia/reperfusion injury in gerbils]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. vol 19. issue 6. 2009-07-09. PMID:17577445. |
to study the effect of nerve growth factor (ngf) pretreatment on apoptosis of neurons and the expression of bcl-2 and bax protein in cerebral cortex and hippocampus ca1 zone following global cerebral ischemia/reperfusion (i/r) injury in gerbils and to explore the mechanism of protection and the best time window of ngf pretreatment. |
2009-07-09 |
2023-08-12 |
Not clear |
| Eun Jeong Choi, Gun-Hee Ki. Hepatoprotective effects of daidzein against 7,12-dimetylbenz[a]anthracene-induced oxidative stress in mice. International journal of molecular medicine. vol 23. issue 5. 2009-07-09. PMID:19360325. |
further, in the dmba-treated mice, apoptosis was induced by a decrease in bcl-2 and an increase in bax. |
2009-07-09 |
2023-08-12 |
mouse |
| Kensuke Kojima, Masaya Shimanuki, Masato Shikami, Michael Andreeff, Hideki Nakakum. Cyclin-dependent kinase 1 inhibitor RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis in AML. Cancer science. vol 100. issue 6. 2009-07-08. PMID:19385969. |
cyclin-dependent kinase 1 inhibitor ro-3306 enhances p53-mediated bax activation and mitochondrial apoptosis in aml. |
2009-07-08 |
2023-08-12 |
Not clear |
| Asima Bhattacharyya, Ranajoy Chattopadhyay, Brent R Burnette, Janet V Cross, Sankar Mitra, Peter B Ernst, Kishor K Bhakat, Sheila E Crow. Acetylation of apurinic/apyrimidinic endonuclease-1 regulates Helicobacter pylori-mediated gastric epithelial cell apoptosis. Gastroenterology. vol 136. issue 7. 2009-07-08. PMID:19505426. |
p53-mediated apoptosis involves p53 activation, bax transcription, and cytochrome c release from mitochondria. |
2009-07-08 |
2023-08-12 |
human |
| X Zhan. Simultaneous exposure to dietary acrylamide and corn oil developed carcinogenesis through cell proliferation and inhibition of apoptosis by regulating p53-mediated mitochondria-dependent signaling pathway. Toxicology and industrial health. vol 25. issue 2. 2009-07-07. PMID:19458132. |
colonic apoptosis and cell proliferation, expression of wild type (wt) p53, bcl-2, bax and caspase-3, were detected at 48 week post acr-exposure. |
2009-07-07 |
2023-08-12 |
rat |
| Qing Lü, Xu-Lin Xu, Zhi He, Xian-Ju Huang, Lian-Jun Guo, Hong-Xing Wan. Guattegaumerine protects primary cultured cortical neurons against oxidative stress injury induced by hydrogen peroxide concomitant with serum deprivation. Cellular and molecular neurobiology. vol 29. issue 3. 2009-07-06. PMID:19015976. |
results of flow cytometry and immunohistochemistry showed that pre-addition of guattegaumerine interrupted the apoptosis of the neurons, reversed the up regulation of the pro-apoptotic gene (bax) and the down regulation of the anti-apoptotic gene (bcl-2). |
2009-07-06 |
2023-08-12 |
rat |
| Man Jiang, Cong-Yi Wang, Shuang Huang, Tianxin Yang, Zheng Don. Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway. American journal of physiology. Renal physiology. vol 296. issue 5. 2009-07-02. PMID:19279129. |
we show that cisplatin could induce bax activation, cytochrome c release, and apoptosis in primary cultures of p53-deficient renal tubular cells, albeit at a level that was lower than in the wild-type cells. |
2009-07-02 |
2023-08-12 |
mouse |
| Man Jiang, Cong-Yi Wang, Shuang Huang, Tianxin Yang, Zheng Don. Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway. American journal of physiology. Renal physiology. vol 296. issue 5. 2009-07-02. PMID:19279129. |
bax and bak, two key molecules in the mitochondrial pathway of apoptosis, were interdependently activated by cisplatin, with bax translocation to and bax/bak oligomerization in mitochondria, leading to cytochrome c release. |
2009-07-02 |
2023-08-12 |
mouse |
| Martina Klee, Kathrin Pallauf, Sonia Alcalá, Aarne Fleischer, Felipe X Pimentel-Muiño. Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak. The EMBO journal. vol 28. issue 12. 2009-07-02. PMID:19339988. |
although it is generally accepted that mitochondrial expression of bak or bax suffices for apoptosis initiated by bh3-only homologues, it is currently unclear whether their reticular counterparts may have a similar potential. |
2009-07-02 |
2023-08-12 |
Not clear |
| Xianwang Wang, Da Xing, Lei Liu, Wei R Che. BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis. FEBS letters. vol 583. issue 12. 2009-07-02. PMID:19427863. |
biml directly neutralizes bcl-xl to promote bax activation during uv-induced apoptosis. |
2009-07-02 |
2023-08-12 |
Not clear |
| Xianwang Wang, Da Xing, Lei Liu, Wei R Che. BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis. FEBS letters. vol 583. issue 12. 2009-07-02. PMID:19427863. |
previous studies indicated that biml was involved in uv-induced apoptosis, but it remains unclear whether bim activates bax by directly engaging it or by releasing it from pro-survival relatives such as bcl-xl. |
2009-07-02 |
2023-08-12 |
Not clear |
| Xianwang Wang, Da Xing, Lei Liu, Wei R Che. BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis. FEBS letters. vol 583. issue 12. 2009-07-02. PMID:19427863. |
thus, our findings provide strong evidence in living cells for the first time that biml initiates apoptosis by abrogating bcl-xl and promoting bax activation under uv irradiation. |
2009-07-02 |
2023-08-12 |
Not clear |
| S Rasul, R Balasubramanian, A Filipović, M J Slade, E Yagüe, R C Coombe. Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells. British journal of cancer. vol 100. issue 12. 2009-07-02. PMID:19513078. |
flow cytometric and western blot analyses indicated that gsi1 induces a g2/m arrest leading to apoptosis, through downregulation of bcl-2, bax and bcl-xl. |
2009-07-02 |
2023-08-12 |
Not clear |
| T Boonmars, T Srisawangwong, P Srirach, B Kaewsamut, S Pinlaor, P Sithithawor. Apoptosis-related gene expressions in hamsters re-infected with Opisthorchis viverrini and re-treated with praziquantel. Parasitology research. vol 102. issue 1. 2009-07-01. PMID:17851691. |
apoptosis gene bcl-2 associated protein x [bax], caspase 9, p53 and protein kinase b [pkb]) was detected by real-time reverse transcription-polymerase chain reaction. |
2009-07-01 |
2023-08-12 |
Not clear |
| Petra Obexer, Judith Hagenbuchner, Thomas Unterkircher, Nora Sachsenmaier, Christoph Seifarth, Günther Böck, Verena Porto, Kathrin Geiger, Michael Ausserlechne. Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis. Molecular biology of the cell. vol 20. issue 7. 2009-07-01. PMID:19211844. |
transgenic survivin exerted a significant antiapoptotic effect and prevented the accumulation of bim and bax at mitochondria, the loss of mitochondrial membrane potential as well as the release of cytochrome c during fkhrl1-induced apoptosis. |
2009-07-01 |
2023-08-12 |
human |
| Sun Mi Kim, So Yong Lee, Dong Yeon Yuk, Dong Cheul Moon, Sang Sook Choi, Youngsoo Kim, Sang Bae Han, Ki-Wan Oh, Jin Tae Hon. Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel. Archives of pharmacal research. vol 32. issue 5. 2009-06-29. PMID:19471891. |
nf-kappab target gene expression of apoptotic cell death proteins (bax, caspase-3, caspase-9) was significantly enhanced, but the expression of anti-apoptotic genes and cell proliferation marker genes (bcl-2, inhibitor of apoptosis protein (iap-1) and x chromosome iap (xiap), cox-2, c-fos, c-jun and cyclin d1) was significantly inhibited by the combined treatment compared to rg3 or docetaxel alone. |
2009-06-29 |
2023-08-12 |
Not clear |