| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Veronika Fedirko, Roberd M Bostick, W Dana Flanders, Qi Long, Aasma Shaukat, Robin E Rutherford, Carrie R Daniel, Vaunita Cohen, Chiranjeev Das. Effects of vitamin D and calcium supplementation on markers of apoptosis in normal colon mucosa: a randomized, double-blind, placebo-controlled clinical trial. Cancer prevention research (Philadelphia, Pa.). vol 2. issue 3. 2009-08-14. PMID:19258546. |
overall expression and colorectal crypt distributions of bcl-2 (an apoptosis inhibitor) and bax (an apoptosis promoter) in biopsies of normal-appearing rectal mucosa were detected by automated immunohistochemistry and quantified by image analysis. |
2009-08-14 |
2023-08-12 |
human |
| Moran Rathaus, Batya Lerrer, Haim Y Cohe. DeubiKuitylation: a novel DUB enzymatic activity for the DNA repair protein, Ku70. Cell cycle (Georgetown, Tex.). vol 8. issue 12. 2009-08-14. PMID:19448404. |
the ku70 protein was shown to be involved in multiple cellular pathways including dna repair, telomere maintenance, v(d)j recombination and bax mediated apoptosis. |
2009-08-14 |
2023-08-12 |
Not clear |
| Narasaiah Kolliputi, Aaron B Waxma. IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation. American journal of physiology. Lung cellular and molecular physiology. vol 297. issue 1. 2009-08-11. PMID:19376889. |
in contrast, specific jnk or p38 kinase inhibitors or treatment with il-6 inhibited bax mitochondrial translocation and apoptosis of huvec. |
2009-08-11 |
2023-08-12 |
mouse |
| Qi Ho. [Effect of Bax translocation on TNFalpha induced apoptosis of human breast cancer MCF7 cells stably expressed hGFP-Bax]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 42. issue 12. 2009-08-10. PMID:18338637. |
[effect of bax translocation on tnfalpha induced apoptosis of human breast cancer mcf7 cells stably expressed hgfp-bax]. |
2009-08-10 |
2023-08-12 |
human |
| Qi Ho. [Effect of Bax translocation on TNFalpha induced apoptosis of human breast cancer MCF7 cells stably expressed hGFP-Bax]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 42. issue 12. 2009-08-10. PMID:18338637. |
the results showed that bax translocation from cytosol into mitochondria was associated with apoptosis induced by tnfalpha in hgfp-bax-tagged mcf7 stable cell line. |
2009-08-10 |
2023-08-12 |
human |
| Qi Ho. [Effect of staurosporine induced apoptosis of MCF7/GFP-Bax stable cell line on Bax translocation from cytosol into mitochondria]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 43. issue 4. 2009-08-10. PMID:18664199. |
[effect of staurosporine induced apoptosis of mcf7/gfp-bax stable cell line on bax translocation from cytosol into mitochondria]. |
2009-08-10 |
2023-08-12 |
Not clear |
| N G Forge. Control of cell number in the sexually dimorphic brain and spinal cord. Journal of neuroendocrinology. vol 21. issue 4. 2009-08-10. PMID:19207822. |
bax is a pro-death gene of the bcl-2 family that is singularly important for apoptosis in neural development. |
2009-08-10 |
2023-08-12 |
mouse |
| Tsung-Lang Chiu, Chin-Cheng S. Curcumin inhibits proliferation and migration by increasing the Bax to Bcl-2 ratio and decreasing NF-kappaBp65 expression in breast cancer MDA-MB-231 cells. International journal of molecular medicine. vol 23. issue 4. 2009-08-07. PMID:19288022. |
our results show that one molecular mechanism of curcumin inhibits the proliferation of mda-mb-231 cells either through up-regulating p21 expression and then inducing apoptosis, or through up-regulating the bax to bcl-2 ratio and then inducing apoptosis. |
2009-08-07 |
2023-08-12 |
human |
| Yasam Dogu, José Día. Mathematical model of a network of interaction between p53 and Bcl-2 during genotoxic-induced apoptosis. Biophysical chemistry. vol 143. issue 1-2. 2009-08-07. PMID:19395147. |
with this information we construct the phase portrait associated with puma induced apoptosis and we found that once the genotoxic injury is produced, bax levels continuously increase. |
2009-08-07 |
2023-08-12 |
Not clear |
| Yasam Dogu, José Día. Mathematical model of a network of interaction between p53 and Bcl-2 during genotoxic-induced apoptosis. Biophysical chemistry. vol 143. issue 1-2. 2009-08-07. PMID:19395147. |
in this work we propose that a possible mechanism for the control of apoptosis is the bax level in the cytoplasm, i.e., bax is continuously released into the cytoplasm, even in absence of puma, according to the kinetic properties of the set of chemical interactions in which the bcl2/bax complex takes part. |
2009-08-07 |
2023-08-12 |
Not clear |
| S Bouali, A-S Chrétien, C Ramacci, M Rouyer, S Marchal, T Galenne, P Juin, P Becuwe, J-L Merli. P53 and PTEN expression contribute to the inhibition of EGFR downstream signaling pathway by cetuximab. Cancer gene therapy. vol 16. issue 6. 2009-08-05. PMID:19165235. |
apoptosis induction was evaluated from bax expression, caspase-3 activation and dna fragmentation analyses. |
2009-08-05 |
2023-08-12 |
Not clear |
| Weidong Han, Jiansheng Xie, Ling Li, Zhen Liu, Xun H. Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis. Apoptosis : an international journal on programmed cell death. vol 14. issue 5. 2009-08-05. PMID:19288276. |
here, we show that shikonin-induced necroptosis can be reverted to apoptosis in the presence of necrostatin-1 (nec-1), a specific necroptosis inhibitor and that the death mode switch is at least partially due to the conversion from mitochondrial inner membrane permeability to mitochondrial outer membrane permeability, which is associated with bax translocation. |
2009-08-05 |
2023-08-12 |
Not clear |
| M Bhattacharjee, S Acharya, A Ghosh, P Sarkar, S Chatterjee, P Kumar, S Chaudhur. Bax and Bid act in synergy to bring about T11TS-mediated glioma apoptosis via the release of mitochondrial cytochrome c and subsequent caspase activation. International immunology. vol 20. issue 12. 2009-07-30. PMID:18931364. |
bax and bid act in synergy to bring about t11ts-mediated glioma apoptosis via the release of mitochondrial cytochrome c and subsequent caspase activation. |
2009-07-30 |
2023-08-12 |
Not clear |
| Reut Kornasio, Ingo Riederer, Gillian Butler-Browne, Vincent Mouly, Zehava Uni, Orna Halev. Beta-hydroxy-beta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. Biochimica et biophysica acta. vol 1793. issue 5. 2009-07-30. PMID:19211028. |
its inhibition of serum-starvation- or staurosporine-induced apoptosis was reflected by less apoptotic cells, reduced bax expression and increased levels of bcl-2 and bcl-x. |
2009-07-30 |
2023-08-12 |
human |
| J Hurst-Kennedy, B D Boyan, Z Schwart. Lysophosphatidic acid signaling promotes proliferation, differentiation, and cell survival in rat growth plate chondrocytes. Biochimica et biophysica acta. vol 1793. issue 5. 2009-07-30. PMID:19233232. |
furthermore, apoptosis induced by either inorganic phosphate or chelerythrine was attenuated by lpa, based on dna fragmentation, tunel staining, caspase-3 activity, and bcl-2:bax protein ratio. |
2009-07-30 |
2023-08-12 |
rat |
| Limin Cai, Xiaomei Li, Shuyun Zheng, Yanhua Wang, Yandong Wang, Haiyan Li, Jing Yang, Jianfang Su. Inhibitor of growth 4 is involved in melanomagenesis and induces growth suppression and apoptosis in melanoma cell line M14. Melanoma research. vol 19. issue 1. 2009-07-30. PMID:19430401. |
overexpression of ing4 could induce growth suppression and apoptosis enhancement in m14 cells, and also induce the upregulation of p27, bax and cyt-c, and the downregulation of cyclind1, skp2, bcl-2, and caspase-3. |
2009-07-30 |
2023-08-12 |
human |
| Young Sook Lee, Hea-Jin Yoon, Jung-Hwa Oh, Han-Jin Park, Eun-Hee Lee, Chang-Woo Song, Seokjoo Yoo. 1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway. Toxicology letters. vol 189. issue 2. 2009-07-30. PMID:19477251. |
1,3-dnb treatment decreased total transcript and protein levels of the apoptosis inhibitory protein bcl-2, and increased expression levels of the pro-apoptotic protein bax. |
2009-07-30 |
2023-08-12 |
mouse |
| Tomasz Urasiński, Elzbieta Urasińska, Jerzy Grabarek, Janusz Fydryk, Wenancjusz Domagał. Good early treatment response in childhood acute lymphoblastic leukemia is associated with Bax nuclear accumulation and PARP cleavage. Medical science monitor : international medical journal of experimental and clinical research. vol 15. issue 6. 2009-07-30. PMID:19478700. |
bax activation and intracellular redistribution as well as its prognostic significance during steroid-induced apoptosis of leukemic cells in childhood acute lymphoblastic leukemia (all) remain a matter of controversy. |
2009-07-30 |
2023-08-12 |
Not clear |
| Yu-Ying Li, Zheng Zhang, Zhuan-Hua Wang, Hong-Wei Wang, Li Zhang, Lei Zh. rBTI induces apoptosis in human solid tumor cell lines by loss in mitochondrial transmembrane potential and caspase activation. Toxicology letters. vol 189. issue 2. 2009-07-30. PMID:19481592. |
rbti-induced apoptosis was shown to involve bax and bak up-regulation, bcl-2 and bcl-xl down-regulation, release of cytochrome c from the mitochondria to the cytosol, activation of caspase-3 and -9 and disruption of the mitochondrial transmembrane potential (deltapsi(m)). |
2009-07-30 |
2023-08-12 |
human |
| Li-li Zhou, Li-na Yang, Li Wan. [The expression of apoptosis related genes Bcl-2 and Bax protein in dysfunctional uterine bleeding]. Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology. vol 22. issue 6. 2009-07-29. PMID:19544644. |
[the expression of apoptosis related genes bcl-2 and bax protein in dysfunctional uterine bleeding]. |
2009-07-29 |
2023-08-12 |
Not clear |