| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peng Wang, Andy Lo, J Bryce Young, Jin H Song, Raymond Lai, Norman M Kneteman, Chunhai Hao, Liang L. Targeted quantitative mass spectrometric identification of differentially expressed proteins between Bax-expressing and deficient colorectal carcinoma cells. Journal of proteome research. vol 8. issue 7. 2009-09-23. PMID:19425606. |
these results indicate the functional diversity of bax and provide new research directions to study the biology of bax-regulated apoptosis. |
2009-09-23 |
2023-08-12 |
Not clear |
| Stanislaw Sulkowski, Andrzej Wincewicz, Mariola Sulkowska, Mariusz Kod. Transforming growth factor-beta1 and regulators of apoptosis. Annals of the New York Academy of Sciences. vol 1171. 2009-09-23. PMID:19723045. |
we aimed at a comparison between cancer expressions of apoptosis regulators, such as p53, bcl-2-associated x protein (bax), and b-cell leukemia/lymphoma extra-long protein (bcl-xl), with tgf-beta1 in malignant and adjacent inflammatory cells in immunohistochemical evaluations of 108 colorectal cancers. |
2009-09-23 |
2023-08-12 |
Not clear |
| Hellinida Thomadaki, Konstantinos V Floros, Andreas Scorila. Molecular response of HL-60 cells to mitotic inhibitors vincristine and taxol visualized with apoptosis-related gene expressions, including the new member BCL2L12. Annals of the New York Academy of Sciences. vol 1171. 2009-09-23. PMID:19723066. |
for further insights into the mechanisms and molecular targets implicated and modified as a result of apoptosis induced by these two mitosis-arresting drugs, we studied the possible alterations, at the mrna level, of various apoptosis-related genes (bcl2, bax, bcl2l12, caspase-3, fas) after leukemia cell (hl-60) treatment with these drugs. |
2009-09-23 |
2023-08-12 |
human |
| Tzu-Ching Kuo, Jai-Sing Yang, Meng-Wei Lin, Shu-Chun Hsu, Jen-Jyh Lin, Hui-Ju Lin, Te-Chun Hsia, Ching-Lung Liao, Mei-Due Yang, Ming-Jen Fan, W G Wood, Jing-Gung Chun. Emodin has cytotoxic and protective effects in rat C6 glioma cells: roles of Mdr1a and nuclear factor kappaB in cell survival. The Journal of pharmacology and experimental therapeutics. vol 330. issue 3. 2009-09-21. PMID:19549930. |
emodin-induced apoptosis was reduced by inhibition of the expression and activation of apoptosis-associated proteins including p53, bax, bcl-2, fas, and caspase-3. |
2009-09-21 |
2023-08-12 |
rat |
| G Chinnadurai, S Vijayalingam, R Rashm. BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes. Oncogene. vol 27 Suppl 1. 2009-09-21. PMID:19641504. |
bik-mediated apoptosis is mediated by selective activation of bax. |
2009-09-21 |
2023-08-12 |
human |
| N N Dania. BAD: undertaker by night, candyman by day. Oncogene. vol 27 Suppl 1. 2009-09-21. PMID:19641507. |
the apoptotic response initiated by the activation of bh3-only proteins ultimately culminates in allosteric activation of pro-apoptotic bax and bak, the gateway proteins to the mitochondrial pathway of apoptosis. |
2009-09-21 |
2023-08-12 |
Not clear |
| N N Dania. BAD: undertaker by night, candyman by day. Oncogene. vol 27 Suppl 1. 2009-09-21. PMID:19641507. |
from activation of bh3-only proteins to oligomerization of bax and bak and mitochondrial outer membrane permeabilization, an intricate network of interactions between the pro- and anti-apoptotic members of the bcl-2 family orchestrates the decision to undergo apoptosis. |
2009-09-21 |
2023-08-12 |
Not clear |
| K S Yee, S Wilkinson, J James, K M Ryan, K H Vousde. PUMA- and Bax-induced autophagy contributes to apoptosis. Cell death and differentiation. vol 16. issue 8. 2009-09-18. PMID:19300452. |
the p53-inducible bh3-only protein puma is a key mediator of p53-dependent apoptosis, and puma has been shown to function by activating bax and mitochondrial outer membrane permeabilization. |
2009-09-18 |
2023-08-12 |
Not clear |
| D Cvejic, S Selemetjev, S Savin, I Paunovic, S Tati. Changes in the balance between proliferation and apoptosis during the progression of malignancy in thyroid tumours. European journal of histochemistry : EJH. vol 53. issue 2. 2009-09-18. PMID:19683979. |
the apoptosis related molecules (bcl-2, bax) and proliferation related marker (pcna) were analysed immunohistochemically in 120 archival cases comprising pmc (n=34), ptc (n=52) and atc (n=34). |
2009-09-18 |
2023-08-12 |
Not clear |
| D Cvejic, S Selemetjev, S Savin, I Paunovic, S Tati. Changes in the balance between proliferation and apoptosis during the progression of malignancy in thyroid tumours. European journal of histochemistry : EJH. vol 53. issue 2. 2009-09-18. PMID:19683979. |
differences were found in the expression of apoptotic molecules (bcl-2 and bax), their ratio (bcl-2 /bax) and in the rate of apoptotic cell death and proliferative activity between pmc, ptc and atc, indicating that disturbances in the balance between apoptosis and proliferation, in favour of the latter, occur gradually during the progression of malignancy in thyroid tumours. |
2009-09-18 |
2023-08-12 |
Not clear |
| J Wang, X F Wang, L G Zhang, S Y Xie, Z L Li, Y J Li, H H Li, F Jia. Involvement of the mitochondrial pathway in p53-independent apoptosis induced by p28GANK knockdown in Hep3B cells. Cytogenetic and genome research. vol 125. issue 2. 2009-09-17. PMID:19729910. |
since p38 can signal to bax, its activation may lead to mitochondrial transmembrane potential (delta psi m) loss, cytochrome c release from mitochondria to cytosol, and caspase-9 activation, eventually triggering the mitochondrial pathway of apoptosis. |
2009-09-17 |
2023-08-12 |
human |
| Morten F Tonnesen, Lars G Grunnet, Josefine Friberg, Alessandra K Cardozo, Nils Billestrup, Décio L Eizirik, Joachim Størling, Thomas Mandrup-Poulse. Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells. Endocrinology. vol 150. issue 9. 2009-09-16. PMID:19556421. |
inhibition of nuclear factor-kappab or bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in ins-1e cells. |
2009-09-16 |
2023-08-12 |
Not clear |
| Stefanie Fister, Andreas R Günthert, Babette Aicher, Klaus W Paulini, Günter Emons, Carsten Gründke. GnRH-II antagonists induce apoptosis in human endometrial, ovarian, and breast cancer cells via activation of stress-induced MAPKs p38 and JNK and proapoptotic protein Bax. Cancer research. vol 69. issue 16. 2009-09-15. PMID:19638591. |
gnrh-ii antagonists induce apoptosis in human endometrial, ovarian, and breast cancer cells via activation of stress-induced mapks p38 and jnk and proapoptotic protein bax. |
2009-09-15 |
2023-08-12 |
human |
| Supachai Yodkeeree, Bokyung Sung, Pornngarm Limtrakul, Bharat B Aggarwa. Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species. Cancer research. vol 69. issue 16. 2009-09-15. PMID:19654295. |
both bax and p21, however, were required for zerumbone to stimulate trail-induced apoptosis. |
2009-09-15 |
2023-08-12 |
human |
| Pankaj Kumar Singh, Raj Kumar, Ashok Sharma, Rajesh Arora, Swatantra Kumar Jain, Rakesh Kumar Sharm. Pifithrin-alpha decreases the radioprotective efficacy of a Podophyllum hexandrum Himalayan mayapple fraction REC-2006 in HepG2 cells. Biotechnology and applied biochemistry. vol 54. issue 1. 2009-09-14. PMID:19409072. |
decrease in the expression of caspase 3 and bax was observed in hepg2 cells when rec-2006 treatment was given 2 h before irradiation; however, pft treatment increased the expression of bax leading to apoptosis. |
2009-09-14 |
2023-08-12 |
Not clear |
| Jing Yu, Vladimir Khaoustov, Yumin Xu, Boris Yoff. [Epicatechin abolished TDCA-induced apoptosis in Huh7 cell by inhibiting Bax, p38 MAPK and ROS production]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 34. issue 10. 2009-09-14. PMID:19673394. |
[epicatechin abolished tdca-induced apoptosis in huh7 cell by inhibiting bax, p38 mapk and ros production]. |
2009-09-14 |
2023-08-12 |
Not clear |
| Arabinda Das, Naren L Banik, Swapan K Ra. Retinoids induce differentiation and downregulate telomerase activity and N-Myc to increase sensitivity to flavonoids for apoptosis in human malignant neuroblastoma SH-SY5Y cells. International journal of oncology. vol 34. issue 3. 2009-09-11. PMID:19212680. |
apoptosis was associated with increases in intracellular free [ca2+], bax expression, cytochrome c release from mitochondria and activities of calpain and caspases. |
2009-09-11 |
2023-08-12 |
human |
| Yonghuan Zhao, Sam K C Chang, Gang Qu, Tianwen Li, Hongbin Cu. Beta-sitosterol inhibits cell growth and induces apoptosis in SGC-7901 human stomach cancer cells. Journal of agricultural and food chemistry. vol 57. issue 12. 2009-09-10. PMID:19456133. |
cells treated with different concentrations of beta-sitosterol also showed changes typical of apoptosis: morphological changes, dna damage, increased expression of pro-caspase-3 and bax (p < 0.05), and activation of pro-caspase-3 and suppression of bcl-2 expression (p < 0.05). |
2009-09-10 |
2023-08-12 |
human |
| Emanuela Mazzon, Concetta Crisafulli, Maria Galuppo, Salvatore Cuzzocre. Role of peroxisome proliferator-activated receptor-alpha in ileum tight junction alteration in mouse model of restraint stress. American journal of physiology. Gastrointestinal and liver physiology. vol 297. issue 3. 2009-09-10. PMID:19556362. |
the absence of a functional ppar-alpha gene in ppar-alpha knockout mice resulted in a significant augmentation of the degree of 1) tnf-alpha production in ileum tissues; 2) the alteration of zonula occludens-1, occludin, and beta-catenin (immunohistochemistry); and 3) apoptosis (terminal deoxynucleotidyltransferase-mediated dutp nick-end labeling staining, bax, bcl-2 expression). |
2009-09-10 |
2023-08-12 |
mouse |
| Yan Cheng, Feng Qiu, Takashi Ikejim. Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells. Autophagy. vol 5. issue 3. 2009-09-09. PMID:19202353. |
in the present study, the exposure of murine fibrosarcoma l929 cells to oridonin led to the generation of intracellular reactive oxygen species (ros) and, subsequently, the ros triggered apoptosis by bax translocation, cytochrome c release and erk activations. |
2009-09-09 |
2023-08-12 |
Not clear |