| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K L Khanduja, S Kumar, N Varma, S C Varma, P K Avti, C M Patha. Enhancement in alpha-tocopherol succinate-induced apoptosis by all-trans-retinoic acid in primary leukemic cells: role of antioxidant defense, Bax and c-myc. Molecular and cellular biochemistry. vol 319. issue 1-2. 2009-06-16. PMID:18642056. |
in conclusion, the data reveal that enhancement of alpha-ts-induced apoptosis by atra in leukemic cells was through up regulation of bax and lipid peroxidation, and down regulation of c-myc and gsh. |
2009-06-16 |
2023-08-12 |
Not clear |
| Takashi Yamagami, Christopher D Porada, Ronald S Pardini, Esmail D Zanjani, Graça Almeida-Porad. Docosahexaenoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line. Cancer biology & therapy. vol 8. issue 4. 2009-06-16. PMID:19197149. |
moreover, expression of the pro-apoptotic protein bax was increased, with resultant skewing in the bax/bcl-2 ratio, providing a mechanistic explanation for the observed dha-induced increase in apoptosis. |
2009-06-16 |
2023-08-12 |
Not clear |
| Lifang Yang, Lanbo Xiao, Xiaoqian Ma, Min Tang, Xinxiang Weng, Xue Chen, Lunquan Sun, Ya Ca. Effect of DNAzymes targeting Akt1 on cell proliferation and apoptosis in nasopharyngeal carcinoma. Cancer biology & therapy. vol 8. issue 4. 2009-06-16. PMID:19276680. |
besides, the apoptosis was shown to be associated with the suppression of the bcl-2 and increased expression of bax. |
2009-06-16 |
2023-08-12 |
mouse |
| Hiroyuki Hamada, Yoshihiko Tashima, Yu Kisaka, Kazunari Iwamoto, Taizo Hanai, Yukihiro Eguchi, Masahiro Okamot. Sophisticated framework between cell cycle arrest and apoptosis induction based on p53 dynamics. PloS one. vol 4. issue 3. 2009-06-15. PMID:19274075. |
in addition, to wreck the equilibrium between bcl-2 and bax the induction of apoptosis required an extreme activation of p53 produced by the oscillation dynamics, and was only implemented after the release of the g2/m phase arrest. |
2009-06-15 |
2023-08-12 |
Not clear |
| Shailaja Kesaraju, Rainald Schmidt-Kastner, Howard M Prentice, Sarah L Milto. Modulation of stress proteins and apoptotic regulators in the anoxia tolerant turtle brain. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476552. |
furthermore, we found no evidence for the anoxic translocation of bax from the cytosol to mitochondria, nor movement of apoptosis inducing factor between the mitochondria and nucleus. |
2009-06-15 |
2023-08-12 |
Not clear |
| Tao Meng, Hai-Ying Chen, Jun Li, Tao Shan. [Expression of lectin-liked oxidized low density lipoprotein receptor-1 and apoptosis associated genes in placenta and the relationship thereof with morbility of early-onset preeclampsia]. Zhonghua yi xue za zhi. vol 88. issue 37. 2009-06-12. PMID:19080712. |
to investigate the expression of lectin-liked oxidized low density lipoprotein receptor-1 (lox-1) and apoptosis associated genes: caspase-3, bax, and bcl-2, in placenta and the relationship thereof with the morbility of early-onset preeclampsia. |
2009-06-12 |
2023-08-12 |
Not clear |
| P Li, S T Zhang, Z L Yu, Y D Wu, X Liu, C M Xu, C H Ch. Effects of cyclooxygenase-2 non-selective and selective inhibitors on proliferation inhibition and apoptosis induction of esophageal squamous carcinoma cells. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. vol 22. issue 1. 2009-06-11. PMID:18564172. |
in ec109 cells, growth arrest was by induction of apoptosis, associated with downregulation of bcl-2, but not bax. |
2009-06-11 |
2023-08-12 |
human |
| K Ross, T Rudel, V Kozjak-Pavlovi. TOM-independent complex formation of Bax and Bak in mammalian mitochondria during TNFalpha-induced apoptosis. Cell death and differentiation. vol 16. issue 5. 2009-06-11. PMID:19165229. |
tom-independent complex formation of bax and bak in mammalian mitochondria during tnfalpha-induced apoptosis. |
2009-06-11 |
2023-08-12 |
Not clear |
| K Ross, T Rudel, V Kozjak-Pavlovi. TOM-independent complex formation of Bax and Bak in mammalian mitochondria during TNFalpha-induced apoptosis. Cell death and differentiation. vol 16. issue 5. 2009-06-11. PMID:19165229. |
after induction of apoptosis, we could not detect any impact of the absence of tom22, tom70, tom40, sam50 or metaxins on the translocation of bax and formation of bax and bak complexes in mitochondria. |
2009-06-11 |
2023-08-12 |
Not clear |
| K Ross, T Rudel, V Kozjak-Pavlovi. TOM-independent complex formation of Bax and Bak in mammalian mitochondria during TNFalpha-induced apoptosis. Cell death and differentiation. vol 16. issue 5. 2009-06-11. PMID:19165229. |
we conclude that the import and assembly machineries of mammalian mitochondria have no impact on the translocation and complex assembly of bax and bak upon apoptosis induction. |
2009-06-11 |
2023-08-12 |
Not clear |
| V Gama, J A Gomez, L D Mayo, M W Jackson, D Danielpour, K Song, A L Haas, M J Laughlin, S Matsuyam. Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization. Cell death and differentiation. vol 16. issue 5. 2009-06-11. PMID:19247369. |
earlier, we have reported that 70 kda subunit of ku protein heterodimer (ku70) binds and inhibits bax activity in the cytosol and that ubiquitin (ub)-dependent proteolysis of cytosolic ku70 facilitates bax-mediated apoptosis. |
2009-06-11 |
2023-08-12 |
human |
| Gabriella Marfe, Marco Tafani, Manuela Indelicato, Paola Sinibaldi-Salimei, Valentina Reali, Bruna Pucci, Massimo Fini, Matteo Antonio Russ. Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction. Journal of cellular biochemistry. vol 106. issue 4. 2009-06-10. PMID:19160423. |
kaempferol induces apoptosis in two different cell lines via akt inactivation, bax and sirt3 activation, and mitochondrial dysfunction. |
2009-06-10 |
2023-08-12 |
human |
| Gabriella Marfe, Marco Tafani, Manuela Indelicato, Paola Sinibaldi-Salimei, Valentina Reali, Bruna Pucci, Massimo Fini, Matteo Antonio Russ. Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction. Journal of cellular biochemistry. vol 106. issue 4. 2009-06-10. PMID:19160423. |
kaempferol treatment induced apoptosis by decreasing the expression of bcl-2 and increasing the expressions of bax. |
2009-06-10 |
2023-08-12 |
human |
| Hirohito Yamaguchi, Nicholas T Woods, Landon G Piluso, Heng-Huan Lee, Jiandong Chen, Kapil N Bhalla, Alvaro Monteiro, Xuan Liu, Mien-Chie Hung, Hong-Gang Wan. p53 acetylation is crucial for its transcription-independent proapoptotic functions. The Journal of biological chemistry. vol 284. issue 17. 2009-06-08. PMID:19265193. |
here we demonstrate that p53 acetylation at lys-320/lys-373/lys-382 is also required for its transcription-independent functions in bax activation, reactive oxygen species production, and apoptosis in response to the histone deacetylase inhibitors (hdaci) suberoylanilide hydroxamic acid and laq824. |
2009-06-08 |
2023-08-12 |
Not clear |
| Nikolaos M Pharmakakis, Ioannis K Petropoulos, Constantine D Georgakopoulos, Chrysoula V Vantzou, Evangelos D Anastassiou, Anestis Mavropoulos, Vassiliki Zolot. Apoptotic mechanisms within the retina in Staphylococcus epidermidis experimental endophthalmitis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. vol 247. issue 5. 2009-06-03. PMID:19039600. |
to investigate the potential involvement of apoptosis and its regulators bcl-2, bax, and fas within the retina in staphylococcus epidermidis experimental endophthalmitis. |
2009-06-03 |
2023-08-12 |
Not clear |
| Xiaoyuan Xu, Yeqiang Liu, Ling Wang, Jun He, Hongfeng Zhang, Xinxiang Chen, Yan Li, Jing Yang, Juan Ta. Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells. International journal of dermatology. vol 48. issue 2. 2009-06-03. PMID:19200201. |
gambogic acid induces apoptosis by regulating the expression of bax and bcl-2 and enhancing caspase-3 activity in human malignant melanoma a375 cells. |
2009-06-03 |
2023-08-12 |
human |
| Do Y Lim, Jung Han Yoon Par. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin. American journal of physiology. Gastrointestinal and liver physiology. vol 296. issue 5. 2009-06-02. PMID:19264955. |
the induction of p53 results in the translocation of bax to the mitochondria, which contributes to fisetin-induced apoptosis in hct-116 cells. |
2009-06-02 |
2023-08-12 |
human |
| R Dornetshuber, M R Kamyar, P Rawnduzi, I Baburin, K Kouri, E Pilz, T Hornbogen, R Zocher, W Berger, R Lemmens-Grube. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochemical pharmacology. vol 77. issue 8. 2009-06-02. PMID:19426683. |
additionally, the cell cycle and apoptosis regulating proteins p53, p21 and bax, but not bcl-2 were shown to impact on pf1022a-induced cytotoxicity. |
2009-06-02 |
2023-08-12 |
human |
| Rebecca Leon, Heng Wu, Ying Jin, Jianning Wei, Chandana Buddhala, Howard Prentice, Jang-Yen W. Protective function of taurine in glutamate-induced apoptosis in cultured neurons. Journal of neuroscience research. vol 87. issue 5. 2009-06-01. PMID:18951478. |
here we propose the mechanisms underlying glutamate-induced apoptosis and taurine's inhibition of glutamate-induced apoptosis to be as follows: glutamate stimulation induces [ca2+](i) elevation, which in turn activates calpain; activation of calpain leads to a reduction of bcl-2:bax ratios; with decreased bcl-2:bax ratios bax homodimers form, bax homodimerization, and translocation to the mitochondria result in the release of cytochrome c; released cytochrome c in turn activates a downstream caspase cascade leading to apoptosis. |
2009-06-01 |
2023-08-12 |
Not clear |
| Bahadir Saatli, Sefa Kizildag, Cemal Posaci, Erbil Dogan, Meral Koyuncuoglu, E Cagnur Ulukus, Nese Atabe. Long-term effects of GnRH agonist, GnRH antagonist, and estrogen plus progesterone treatment on apoptosis related genes in rat ovary. Fertility and sterility. vol 91. issue 5 Suppl. 2009-05-29. PMID:18829022. |
to define the long-term effects of gnrh antagonist, gnrh agonist, and estrogen plus progesterone treatments on apoptosis and apoptosis-related gene expressions, including bcl2, bax, and cyt c in rat ovary. |
2009-05-29 |
2023-08-12 |
rat |