| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tatiana K Rostovtseva, Hacène Boukari, Antonella Antignani, Brian Shiu, Soojay Banerjee, Albert Neutzner, Richard J Youl. Bax activates endophilin B1 oligomerization and lipid membrane vesiculation. The Journal of biological chemistry. vol 284. issue 49. 2009-12-22. PMID:19805544. |
although endo b1 does not bind bax in healthy cells, during apoptosis, endo b1 interacts transiently with bax and promotes cytochrome c release from mitochondria. |
2009-12-22 |
2023-08-12 |
Not clear |
| Tatiana K Rostovtseva, Hacène Boukari, Antonella Antignani, Brian Shiu, Soojay Banerjee, Albert Neutzner, Richard J Youl. Bax activates endophilin B1 oligomerization and lipid membrane vesiculation. The Journal of biological chemistry. vol 284. issue 49. 2009-12-22. PMID:19805544. |
this activity of purified bax protein to induce cell-free assembly of endo b1 may reflect its activity in cells that regulates apoptosis and/or mitochondrial fusion. |
2009-12-22 |
2023-08-12 |
Not clear |
| Chih-Lung Lin, Aaron S Dumont, Yee-Jean Tsai, Jih-Hui Huang, Kao-Ping Chang, Aij-Lie Kwan, Yi-Ren Hong, Shen-Long Hown. 17Beta-estradiol activates adenosine A(2a) receptor after subarachnoid hemorrhage. The Journal of surgical research. vol 157. issue 2. 2009-12-21. PMID:19181336. |
this study tests the hypothesis that e2 attenuates sah-induced vasospasm and apoptosis by activating adenosine ar-a(2a) and extracellular signal-regulated kinase 1 and 2 (erk1/2), and by altering antiapoptotic and proapoptotic protein expression (bcl-2 and bax, respectively). |
2009-12-21 |
2023-08-12 |
Not clear |
| Chun Gao, Ai-Ying Wan. Significance of increased apoptosis and Bax expression in human small intestinal adenocarcinoma. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 57. issue 12. 2009-12-21. PMID:19729672. |
significance of increased apoptosis and bax expression in human small intestinal adenocarcinoma. |
2009-12-21 |
2023-08-12 |
human |
| Chun Gao, Ai-Ying Wan. Significance of increased apoptosis and Bax expression in human small intestinal adenocarcinoma. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 57. issue 12. 2009-12-21. PMID:19729672. |
in conclusion, increased apoptosis and expression of bax, not bcl-2 or the bax/bcl-2 ratio, may play some role in the relatively lower incidence of human small intestinal carcinomas. |
2009-12-21 |
2023-08-12 |
human |
| Qiong Wang, Min Liu, Xin Li, Lu Chen, Hua Tan. Kazrin F is involved in apoptosis and interacts with BAX and ARC. Acta biochimica et biophysica Sinica. vol 41. issue 9. 2009-12-17. PMID:19727525. |
kazrin f is involved in apoptosis and interacts with bax and arc. |
2009-12-17 |
2023-08-12 |
Not clear |
| Qiong Wang, Min Liu, Xin Li, Lu Chen, Hua Tan. Kazrin F is involved in apoptosis and interacts with BAX and ARC. Acta biochimica et biophysica Sinica. vol 41. issue 9. 2009-12-17. PMID:19727525. |
co-immunoprecipitation analysis revealed that kazrin f interacts with arc (apoptosis repressor with caspase recruitment domain) and bax (bcl-2-associated x protein). |
2009-12-17 |
2023-08-12 |
Not clear |
| Qiong Wang, Min Liu, Xin Li, Lu Chen, Hua Tan. Kazrin F is involved in apoptosis and interacts with BAX and ARC. Acta biochimica et biophysica Sinica. vol 41. issue 9. 2009-12-17. PMID:19727525. |
these results suggested that kazrin f might play an important role in regulating cellular apoptosis by interacting with arc and bax. |
2009-12-17 |
2023-08-12 |
Not clear |
| E Mortola, A Larse. [Bluetongue virus infection: signaling pathway activated during apoptosis]. Revista Argentina de microbiologia. vol 41. issue 3. 2009-12-17. PMID:19831310. |
to elucidate the apoptosis pathways in btv infection, we have examined in detail the apoptosis mechanism by examination of caspases, bax, cytochrome c, smac/diablo and nf-b signalling pathways. |
2009-12-17 |
2023-08-12 |
Not clear |
| E Mortola, A Larse. [Bluetongue virus infection: signaling pathway activated during apoptosis]. Revista Argentina de microbiologia. vol 41. issue 3. 2009-12-17. PMID:19831310. |
our accumulating data concerning the activation of bax, cytochrome c, smac/diablo and nf-kappab clarify the mechanism of apoptosis during btv infection, and confer a better understanding of the primary role of apoptosis in btv pathogenesis. |
2009-12-17 |
2023-08-12 |
Not clear |
| T W Owens, A J Valentijn, J-P Upton, J Keeble, L Zhang, J Lindsay, N K Zouq, A P Gilmor. Apoptosis commitment and activation of mitochondrial Bax during anoikis is regulated by p38MAPK. Cell death and differentiation. vol 16. issue 11. 2009-12-16. PMID:19662026. |
apoptosis commitment and activation of mitochondrial bax during anoikis is regulated by p38mapk. |
2009-12-16 |
2023-08-12 |
Not clear |
| T W Owens, A J Valentijn, J-P Upton, J Keeble, L Zhang, J Lindsay, N K Zouq, A P Gilmor. Apoptosis commitment and activation of mitochondrial Bax during anoikis is regulated by p38MAPK. Cell death and differentiation. vol 16. issue 11. 2009-12-16. PMID:19662026. |
during apoptosis, bax translocates from the cytosol to the outer mitochondrial membrane (omm), wherein it contributes to the formation of pores to release cytochrome-c. |
2009-12-16 |
2023-08-12 |
Not clear |
| T W Owens, A J Valentijn, J-P Upton, J Keeble, L Zhang, J Lindsay, N K Zouq, A P Gilmor. Apoptosis commitment and activation of mitochondrial Bax during anoikis is regulated by p38MAPK. Cell death and differentiation. vol 16. issue 11. 2009-12-16. PMID:19662026. |
artificially targeting p38mapk to the omm increased the kinetics of anoikis, supporting a requirement for its mitochondrial localisation to regulate bax activation and drive commitment to apoptosis. |
2009-12-16 |
2023-08-12 |
Not clear |
| Melisa Bunderson-Schelvan, Amy K Erbe, Corbin Schwanke, Mark A Pershous. Suppression of the mouse double minute 4 gene causes changes in cell cycle control in a human mesothelial cell line responsive to ultraviolet radiation exposure. Environmental and molecular mutagenesis. vol 50. issue 9. 2009-12-15. PMID:19472317. |
changes in cell growth as well as differences in the regulation of direct transcriptional targets of tp53, cdkn1a (cyclin-dependent kinase 1alpha, p21) and bax, suggest a shift from cell cycle arrest to apoptosis upon increasing uv exposure. |
2009-12-15 |
2023-08-12 |
mouse |
| S Karmakar, S Roy Choudhury, N L Banik, S K Ra. Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19540315. |
combination of 4-hpr and gst increased bax:bcl-2 ratio, mitochondrial release of smac, downregulation of baculovirus inhibitor-of-apoptosis repeat containing (birc) proteins including birc-2 and birc-3, and activation of caspase-3 and apoptosis inducing factor (aif). |
2009-12-15 |
2023-08-12 |
mouse |
| Hayato Hikita, Tetsuo Takehara, Takahiro Kodama, Satoshi Shimizu, Atsushi Hosui, Takuya Miyagi, Tomohide Tatsumi, Hisashi Ishida, Kazuyoshi Ohkawa, Wei Li, Tatsuya Kanto, Naoki Hiramatsu, Lothar Hennighausen, Xiao-Ming Yin, Norio Hayash. BH3-only protein bid participates in the Bcl-2 network in healthy liver cells. Hepatology (Baltimore, Md.). vol 50. issue 6. 2009-12-15. PMID:19839062. |
we generated bcl-xl ko, bcl-xl/bid double ko, bcl-xl/bak double ko, bcl-xl/bax double ko, and bcl-xl/bak/bax triple ko mice and found that hepatocyte apoptosis caused by bcl-xl deficiency was completely dependent on bak and bax, and surprisingly on bid. |
2009-12-15 |
2023-08-12 |
mouse |
| Scott B Widenmaier, Ziliang Ao, Su-Jin Kim, Garth Warnock, Christopher H S McIntos. Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide. The Journal of biological chemistry. vol 284. issue 44. 2009-12-14. PMID:19748889. |
sts induced translocation of bad and bimel, activation of mitochondrial bax, release of mitochondrial cytochrome c, cleavage of caspase-3, and apoptosis. |
2009-12-14 |
2023-08-12 |
human |
| Yong-Lie Zhou, Ya-Ping Lü, Wei-Xiao Hu, Lian-Nü Qiu, Wen-Song Wang, Jian-Dong Liu, Jian-Guo W. [ZGDHu-1-inducing apoptosis of SHI-1 leukemia cells and its molecular mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 3. 2009-12-11. PMID:17605850. |
different concentrations of zgdhu-1 and different times of culture were used to treat shi-1 cells; the apoptosis of shi-1 cells was analyzed by morphology, dna agarose gel electrophoresis, dna content detection, annexin-v/pi and hoechst33258 labeling method, the mitochondrial transmembrane potential (delta psi m) were measured by dihydrorhodamin 123, and expressions of bcl-2, bax, fas, p53 and mitochondrial membrane protein were analyzed by flow cytometry, while the bcl-2, bax and p53 gene were analyzed by rt-pcr. |
2009-12-11 |
2023-08-12 |
human |
| Marcus Maier, Emanuel V Geiger, Dirk Henrich, Ramin Ebrahimi, Sebastian Wutzler, Mark Lehnert, Ingo Marz. Apoptosis differs in dendritic cell subsets early after severe trauma. Human immunology. vol 70. issue 10. 2009-12-11. PMID:19589364. |
expression of genes involved in apoptosis (caspase-8, flice inhibitory protein [flip], bcl-2, bax, gadd45) in dc was measured by reverse transcriptase polymerase chain reaction. |
2009-12-11 |
2023-08-12 |
human |
| Cunnan Dong, Yang Wang, Yi Zhun Zh. Asymmetric synthesis and biological evaluation of Danshensu derivatives as anti-myocardial ischemia drug candidates. Bioorganic & medicinal chemistry. vol 17. issue 9. 2009-12-09. PMID:19359186. |
furthermore, 1a and 4c could inhibit apoptosis by regulating the expression of apoptosis-related molecule in gene and protein levels, up-regulating the expression of bcl-2 and down-regulating bax and caspase-3. |
2009-12-09 |
2023-08-12 |
Not clear |