| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Nakano, Tatsuya Ohno, Hitoshi Ishikawa, Yoshiyuki Suzuki, Takeo Takahash. Current advancement in radiation therapy for uterine cervical cancer. Journal of radiation research. vol 51. issue 1. 2010-05-25. PMID:20173313. |
the biological factors overviewed in this article include hypoxia relating factors of hif-1alpha, sod, cell cycle parameters of pmi, proliferation factors of ki67, egfr, cerbb2, cox-2, cycle regulation proteins p53, p21, apoptosis regulation proteins bcl2 and bax and so on. |
2010-05-25 |
2023-08-12 |
human |
| Jin Chai, Qi Xiong, Pengpeng Zhang, Rong Zheng, Jian Peng, Siwen Jian. Induction of Ca2+ signal mediated apoptosis and alteration of IP3R1 and SERCA1 expression levels by stress hormone in differentiating C2C12 myoblasts. General and comparative endocrinology. vol 166. issue 2. 2010-05-24. PMID:19723525. |
furthermore, the imbalance of calcium homeostasis increased the level of bax, decreased the level of bcl-2, induced cytochrome c release and activated caspase-3, leading to intranucleosomal dna fragmentation and plasma membrane damage, eventually resulting in cell apoptosis. |
2010-05-24 |
2023-08-12 |
Not clear |
| Emil Rudolf, Miroslav Cervink. Zinc pyrithione induces cellular stress signaling and apoptosis in Hep-2 cervical tumor cells: the role of mitochondria and lysosomes. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 23. issue 2. 2010-05-24. PMID:20151177. |
moreover, zinc activates p53 and its dependent genes including puma and bax and they contribute to an observed loss of mitochondrial membrane potential and activation of apoptosis. |
2010-05-24 |
2023-08-12 |
Not clear |
| Andrzej Wincewicz, Mariusz Koda, Mariola Sulkowska, Luiza Kanczuga-Koda, Dominik Wincewicz, Stanislaw Sulkowsk. STAT3 and hypoxia induced proteins--HIF-1alpha, EPO and EPOR in relation with Bax and Bcl-xL in nodal metastases of ductal breast cancers. Folia histochemica et cytobiologica. vol 47. issue 3. 2010-05-24. PMID:20164027. |
our present study was focused on immunohistochemical evaluation of stat3, hif-1alpha, epo and epor in relation to apoptosis regulators, bax and bcl-xl in 39 metastases of ductal breast cancers to lymph nodes. |
2010-05-24 |
2023-08-12 |
Not clear |
| Lingling Zhang, Yingjie Zhang, Da Xin. LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3beta-inactivation mechanism. Journal of cellular physiology. vol 224. issue 1. 2010-05-24. PMID:20333643. |
lpli inhibits apoptosis upstream of bax translocation via a gsk-3beta-inactivation mechanism. |
2010-05-24 |
2023-08-12 |
Not clear |
| Lingling Zhang, Yingjie Zhang, Da Xin. LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3beta-inactivation mechanism. Journal of cellular physiology. vol 224. issue 1. 2010-05-24. PMID:20333643. |
taken together, we conclude that lpli protects against sts-induced apoptosis upstream of bax translocation via the pi3k/akt/gsk-3beta pathway. |
2010-05-24 |
2023-08-12 |
Not clear |
| Javier Espino, Ignacio Bejarano, Pedro C Redondo, Juan A Rosado, Carmen Barriga, Russel J Reiter, José A Pariente, Ana B Rodrígue. Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation. The Journal of membrane biology. vol 233. issue 1-3. 2010-05-20. PMID:20130848. |
melatonin reduces apoptosis induced by calcium signaling in human leukocytes: evidence for the involvement of mitochondria and bax activation. |
2010-05-20 |
2023-08-12 |
human |
| Harjotaruno Sukardiman, Aty Widyawaruyanti, Sismindari, Noor Cholies Zain. Apoptosis inducing effect of andrographolide on TD-47 human breast cancer cell line. African journal of traditional, complementary, and alternative medicines : AJTCAM. vol 4. issue 3. 2010-05-20. PMID:20161898. |
andrographolide isolated from andrographis paniculata ness (acanthaceae) at 0.35 mm, 0.70 mm and 1.40 mm induced dna fragmentation and increased the percentage of apoptotic cells when td-47 human breast cancer cell line was treated for 24, 48 and 72 h. the results demonstrated that andrographolide can induce apoptosis in td-47 human breast cancer cell line in a time and concentration-dependent manner by increase expression of p53, bax, caspase-3 and decrease expression of bcl-2 determined by immunohistochemical analysis. |
2010-05-20 |
2023-08-12 |
human |
| Hasmah Abdullah, Azimahtol Hawariah Lope Pihie, Judit Hohmann, Joseph Molná. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer cell international. vol 10. 2010-05-20. PMID:20441573. |
a natural compound from hydnophytum formicarium induces apoptosis of mcf-7 cells via up-regulation of bax. |
2010-05-20 |
2023-08-12 |
human |
| Wen-juan Ji, Qiang Qu, Ye Jin, Lei Zhao, Xiao-dong H. [Ursodeoxycholic acid inhibits hepatocyte-like cell apoptosis by down-regulating the expressions of Bax and Caspase-3]. Zhonghua yi xue za zhi. vol 89. issue 42. 2010-05-18. PMID:20137712. |
[ursodeoxycholic acid inhibits hepatocyte-like cell apoptosis by down-regulating the expressions of bax and caspase-3]. |
2010-05-18 |
2023-08-12 |
Not clear |
| Ling-Ling Yao, Xiao-Wei Huang, Yong-Gang Wang, Yin-Xiang Cao, Cai-Cai Zhang, Yi-Chun Zh. Hydrogen sulfide protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by preventing GSK-3beta-dependent opening of mPTP. American journal of physiology. Heart and circulatory physiology. vol 298. issue 5. 2010-05-18. PMID:20154265. |
transfection of a phosphorylation-resistant mutant of gsk-3beta at ser9 attenuated the effects of nahs in reducing cardiomyocyte apoptosis, bax translocation, caspase-3 activation, and mptp opening. |
2010-05-18 |
2023-08-12 |
rat |
| Wobbe Bouma, Mio Noma, Shinya Kanemoto, Muneaki Matsubara, Bradley G Leshnower, Robin Hinmon, Joseph H Gorman, Robert C Gorma. Sex-related resistance to myocardial ischemia-reperfusion injury is associated with high constitutive ARC expression. American journal of physiology. Heart and circulatory physiology. vol 298. issue 5. 2010-05-18. PMID:20173041. |
we sought to quantitatively assess the effect of sex, ovarian hormone loss, and i/r on myocardial bax, bcl-2, and apoptosis repressor with caspase recruitment domain (arc) expression. |
2010-05-18 |
2023-08-12 |
Not clear |
| Nuria López-Royuela, Patricia Balsas, Patricia Galán-Malo, Alberto Anel, Isabel Marzo, Javier Nava. Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells. Biochimica et biophysica acta. vol 1803. issue 2. 2010-05-17. PMID:19914305. |
we show here that dexamethasone (dex)-induced apoptosis in mm.1s and opm-2 cells is characterized by bax and bak conformational changes, deltapsi(m) loss, cytochrome c release and caspase-3 activation. |
2010-05-17 |
2023-08-12 |
human |
| Sun Mi Kim, So Yong Lee, Jin Suk Cho, Seung Mo Son, Sang Sook Choi, Yeo Pyo Yun, Hwan Soo Yoo, Do Young Yoon, Ki-Wan Oh, Sang Bae Han, Jin Tae Hon. Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB. European journal of pharmacology. vol 631. issue 1-3. 2010-05-17. PMID:20056115. |
it was also found that nf-kappab target gene expression of bax, caspase-3, and caspase-9 was much more significantly enhanced, but the expression of bcl-2, inhibitor of apoptosis protein (iap-1) and x chromosome iap (xiap), and the expression of cell cycle regulatory proteins cyclin b, d1 and e, and cyclin dependent kinases 2 and 4 was also much more significantly inhibited by the combination treatment. |
2010-05-17 |
2023-08-12 |
human |
| M Nemethova, V Danielisova, M Gottlieb, P Kravcukova, J Burd. Ischemic postconditioning in the rat hippocampus: mapping of proteins involved in reversal of delayed neuronal death. Archives italiennes de biologie. vol 148. issue 1. 2010-05-14. PMID:20426251. |
we have examined immunoreactivity of antioxidant enzymes (mnsod, cuznsod) and proteins related to apoptosis development (bcl-2, bax). |
2010-05-14 |
2023-08-12 |
rat |
| Shi-jie Wang, Xiong Guo, Yin-gang Zhang, Feng-ling Ren, Shuang-qing Peng, Jun-ling Cao, Zhong-li Shi, Zeng-tie Zhan. [Butenolide induces apoptosis of cultured chondrocytes: study of its mechanism]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 27. issue 4. 2010-05-11. PMID:17545017. |
to observe cell apoptosis and bcl-2 and bax expression changes of chondrocytes induced by butenolide (but) and the inhibitory effect of selenium against but-induced chondrcyte apoptosis, to gain insights into the mechanism by which but induces chondrcyte apoptosis. |
2010-05-11 |
2023-08-12 |
Not clear |
| Marija Kastelan, Larisa Prpić Massari, Ines Braja. [The role of bcl-2 family proteins in psoriasis]. Lijecnicki vjesnik. vol 132. issue 1-2. 2010-05-11. PMID:20359157. |
the process of apoptosis is controlled by proteins of the bcl-2 family, several proapoptotic (bax, bak, bad) and antiapoptotic (bcl-2, bcl-x(l)) proteins. |
2010-05-11 |
2023-08-12 |
Not clear |
| Ahmed Malki, Muhammad El-Saadani, Ahmed S Sulta. Garlic constituent diallyl trisulfide induced apoptosis in MCF7 human breast cancer cells. Cancer biology & therapy. vol 8. issue 22. 2010-05-10. PMID:19823037. |
furthermore, the dats-induced apoptosis was correlated with induction of pro-apoptotic bax protein and p53 protein expression was upregulated and translocation to nucleus in mcf-7 cells. |
2010-05-10 |
2023-08-12 |
human |
| M Filali, N Frydman, M P Belot, L Hesters, F Gaudin, G Tachdjian, D Emilie, R Frydman, V Machelo. Oocyte in-vitro maturation: BCL2 mRNA content in cumulus cells reflects oocyte competency. Reproductive biomedicine online. vol 19 Suppl 4. 2010-05-10. PMID:20034411. |
bcl2-associated x protein (bax) and b-cell leukaemia/lymphoma gene-2 (bcl2), which are, respectively, pro- and anti-apoptotic proteins of the bcl2 gene family, participate in the mitochondria-dependent apoptosis pathway. |
2010-05-10 |
2023-08-12 |
Not clear |
| Cordula Hemrajani, Cedric N Berger, Keith S Robinson, Olivier Marchès, Aurelie Mousnier, Gad Franke. NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 7. 2010-05-10. PMID:20133763. |
nleh effectors interact with bax inhibitor-1 to block apoptosis during enteropathogenic escherichia coli infection. |
2010-05-10 |
2023-08-12 |
mouse |