| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meng-Liang Lin, Yao-Cheng Lu, Hong-Lin Su, Hsin-Ting Lin, Chuan-Chun Lee, Shang-En Kang, Tan-Chen Lai, Jing-Gung Chung, Shih-Shun Che. Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. Journal of cellular biochemistry. vol 112. issue 4. 2011-08-01. PMID:21308745. |
ectopic expression of bcl-x(l) and sirna-mediated bax attenuation significantly inhibited apoptosis induced by ae. |
2011-08-01 |
2023-08-12 |
human |
| Meng-Liang Lin, Yao-Cheng Lu, Hong-Lin Su, Hsin-Ting Lin, Chuan-Chun Lee, Shang-En Kang, Tan-Chen Lai, Jing-Gung Chung, Shih-Shun Che. Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. Journal of cellular biochemistry. vol 112. issue 4. 2011-08-01. PMID:21308745. |
z-ietd-fmk inhibited ae-induced apoptosis, bax expression, bid cleavage, translocation of tbid to mitochondria, erk phosphorylation, caspase-9 activation, and the release of cytochrome c, apoptosis-inducing factor (aif), and endonuclease g from mitochondria. |
2011-08-01 |
2023-08-12 |
human |
| Yi Zhang, Xiaoman Xu, Ping H. Tubeimoside-1 inhibits proliferation and induces apoptosis by increasing the Bax to Bcl-2 ratio and decreasing COX-2 expression in lung cancer A549 cells. Molecular medicine reports. vol 4. issue 1. 2011-08-01. PMID:21461558. |
tubeimoside-1 inhibits proliferation and induces apoptosis by increasing the bax to bcl-2 ratio and decreasing cox-2 expression in lung cancer a549 cells. |
2011-08-01 |
2023-08-12 |
human |
| Yi Zhang, Xiaoman Xu, Ping H. Tubeimoside-1 inhibits proliferation and induces apoptosis by increasing the Bax to Bcl-2 ratio and decreasing COX-2 expression in lung cancer A549 cells. Molecular medicine reports. vol 4. issue 1. 2011-08-01. PMID:21461558. |
tbms1 treatment induced apoptosis by decreasing the expression of bcl-2 and increasing the expression of bax in the a549 cells. |
2011-08-01 |
2023-08-12 |
human |
| Jeffrey S Warren, Ying Zhao, Raymond Yung, Anjali Desa. Recombinant human erythropoietin suppresses endothelial cell apoptosis and reduces the ratio of Bax to Bcl-2 proteins in the aortas of apolipoprotein E-deficient mice. Journal of cardiovascular pharmacology. vol 57. issue 4. 2011-07-29. PMID:21242808. |
recombinant human erythropoietin suppresses endothelial cell apoptosis and reduces the ratio of bax to bcl-2 proteins in the aortas of apolipoprotein e-deficient mice. |
2011-07-29 |
2023-08-12 |
mouse |
| Peiju Qiu, Huashi Guan, Ping Dong, Shiming Li, Chi-Tang Ho, Min-Hsiung Pan, David Julian McClements, Hang Xia. The p53-, Bax- and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones. Molecular nutrition & food research. vol 55. issue 4. 2011-07-29. PMID:21462329. |
herein, using isogenic variants of hct116 human colon cancer cells, we investigated the effects of p53, bax and p21 on the apoptosis and cell-cycle arrest induced by different 5oh-pmfs. |
2011-07-29 |
2023-08-12 |
human |
| Xuguang Zhang, Xiangwen Peng, Weiping Yu, Shaoying Hou, Yan Zhao, Zhihong Zhang, Xiaoli Huang, Kun W. Alpha-tocopheryl succinate enhances doxorubicin-induced apoptosis in human gastric cancer cells via promotion of doxorubicin influx and suppression of doxorubicin efflux. Cancer letters. vol 307. issue 2. 2011-07-28. PMID:21536373. |
furthermore, combination of doxo+α-tos induced increased levels of fas and bax protein expression and cleavage of caspase-8 and caspase-9, suggesting that combination treatment induced fas/caspase-8 and bax mediated mitochondria dependent apoptosis. |
2011-07-28 |
2023-08-12 |
human |
| Kavitha Venkatesh, Sharmila Govindaraj, Arunkumar Ramachandran, Senthilkumar Kalimuthu, Elumalai Perumal, Sivakamasundari Velayutham, Arunakaran Jagadeesa. Effect of ukrain on cell survival and apoptosis in the androgen-independent prostate cancer cell line PC-3. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 30. issue 1. 2011-07-26. PMID:21609312. |
ukrain significantly increased the pro-apoptotic mrna expression of bad, bax, and fasl; decreased the cell survival protein p-akt and the anti-apoptotic protein bcl-2; and increased the protein levels of cleaved poly(adp)-ribose polymerase (parp) and caspase-10.the results of this study suggest that ukrain decreases the cell survival of androgen-independent prostate cancer cells and induces their apoptosis, thus supporting its use as a therapeutic drug for the treatment of prostate cancer |
2011-07-26 |
2023-08-12 |
Not clear |
| P Pratheeshkumar, Girija Kutta. Oleanolic acid induces apoptosis by modulating p53, Bax, Bcl-2 and caspase-3 gene expression and regulates the activation of transcription factors and cytokine profile in B16F. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 30. issue 1. 2011-07-26. PMID:21609313. |
oleanolic acid induces apoptosis by modulating p53, bax, bcl-2 and caspase-3 gene expression and regulates the activation of transcription factors and cytokine profile in b16f. |
2011-07-26 |
2023-08-12 |
Not clear |
| Yong-Yu Liu, Gauri A Patwardhan, Kaustubh Bhinge, Vineet Gupta, Xin Gu, S Michal Jazwinsk. Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells. Cancer research. vol 71. issue 6. 2011-07-25. PMID:21278235. |
gcs silencing increased the levels of phosphorylated p53 and p53-responsive genes, including p21(waf1/cip1), bax, and puma, consistent with a redirection of the mutant p53 cells to apoptosis. |
2011-07-25 |
2023-08-12 |
human |
| Xuesong Yang, Yuejian Liu, Jiwei Liu, Xiaoqi Wang, Qiu Ya. Cyclophosphamide-induced apoptosis in A431 cells is inhibited by fucosyltransferase IV. Journal of cellular biochemistry. vol 112. issue 5. 2011-07-20. PMID:21337384. |
we concluded that fut4 inhibited cell apoptosis induced by cpa through decreasing the expression of apoptotic proteins bax, caspase 3, and parp and increasing the expression of anti-apoptotic protein bcl-2 via the erk/mapk and pi3k/akt signaling pathways in a431 cells. |
2011-07-20 |
2023-08-12 |
Not clear |
| Yuichi Kimura, Chizuru Sugimoto, Tetsuji Takabayashi, Takeshi Tanaka, Akihiro Kojima, Norihiko Narita, Shigeharu Fujied. Bax-gene transfer enhances apoptosis by steroid treatment in human nasal fibroblasts. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 267. issue 1. 2011-07-19. PMID:19636580. |
the bax and bcl-2 proteins play important roles in the regulation of apoptosis. |
2011-07-19 |
2023-08-12 |
human |
| Yuichi Kimura, Chizuru Sugimoto, Tetsuji Takabayashi, Takeshi Tanaka, Akihiro Kojima, Norihiko Narita, Shigeharu Fujied. Bax-gene transfer enhances apoptosis by steroid treatment in human nasal fibroblasts. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 267. issue 1. 2011-07-19. PMID:19636580. |
the bax accelerates apoptosis. |
2011-07-19 |
2023-08-12 |
human |
| Yuichi Kimura, Chizuru Sugimoto, Tetsuji Takabayashi, Takeshi Tanaka, Akihiro Kojima, Norihiko Narita, Shigeharu Fujied. Bax-gene transfer enhances apoptosis by steroid treatment in human nasal fibroblasts. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 267. issue 1. 2011-07-19. PMID:19636580. |
in this study, we investigated whether the overexpression of bax in human fibroblasts influences apoptosis by treatment with a steroid (prednisolone) in vitro. |
2011-07-19 |
2023-08-12 |
human |
| Yuichi Kimura, Chizuru Sugimoto, Tetsuji Takabayashi, Takeshi Tanaka, Akihiro Kojima, Norihiko Narita, Shigeharu Fujied. Bax-gene transfer enhances apoptosis by steroid treatment in human nasal fibroblasts. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 267. issue 1. 2011-07-19. PMID:19636580. |
we found that the transfer of the exogenous bax gene enhanced the induction of apoptosis by steroid-treatment in human nasal fibroblasts. |
2011-07-19 |
2023-08-12 |
human |
| Carla Loreto, Giuseppe Musumeci, Alessandro Castorina, Corrado Loreto, Giuseppa Martine. Degenerative disc disease of herniated intervertebral discs is associated with extracellular matrix remodeling, vimentin-positive cells and cell death. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 193. issue 2. 2011-07-19. PMID:21330123. |
mmp-9 expression seems to relate to disc damage, while chondrocyte bax upregulation and tunel+ cell staining revealed apoptosis activation regardless of patient age. |
2011-07-19 |
2023-08-12 |
human |
| Carolina S Ilkow, Ing Swie Goping, Tom C Hobma. The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax. PLoS pathogens. vol 7. issue 2. 2011-07-19. PMID:21379337. |
the main mechanism of action was specific for bax as capsid bound bax and prevented bax-induced apoptosis but did not bind bak nor inhibit bak-induced apoptosis. |
2011-07-19 |
2023-08-12 |
Not clear |
| Di Chen, Jiping Tang, Nikan H Khatibi, Mei Zhu, Yingbo Li, Chengyuan Wang, Rong Jiang, Liu Tu, Shali Wan. Treatment with Z-ligustilide, a component of Angelica sinensis, reduces brain injury after a subarachnoid hemorrhage in rats. The Journal of pharmacology and experimental therapeutics. vol 337. issue 3. 2011-07-19. PMID:21398513. |
additional testing was done to evaluate for apoptosis using tdt-mediated dutp-biotin nick end labeling staining as well as immunohistochemistry and western blotting to identify key proapoptotic/survival proteins, i.e., p53, bax, bcl-2, and cleaved caspase-3. |
2011-07-19 |
2023-08-12 |
rat |
| Barbora Juhásová, Ingrid Bhatia-Kiššová, Katarína Polčicová, Marek Mentel, Michael Forte, Peter Polči. Reconstitution of interactions of Murine gammaherpesvirus 68 M11 with Bcl-2 family proteins in yeast. Biochemical and biophysical research communications. vol 407. issue 4. 2011-07-19. PMID:21439939. |
to study a role of m11 in regulation of apoptosis we have established a yeast model system in which the action of m11 together with proapoptotic proteins bax, bak and bid can be studied. |
2011-07-19 |
2023-08-12 |
Not clear |
| Huiquan Lou, Kuljeet Kaur, Anita K Sharma, Pawan K Singa. Adriamycin-induced oxidative stress, activation of MAP kinases and apoptosis in isolated cardiomyocytes. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 13. issue 2. 2011-07-14. PMID:16580821. |
changes due to adr in mitogen-activated protein kinases (erk1/2 and p38 mapks), pro- and anti-apoptotic proteins (bax and bcl-xl) and apoptosis were examined in isolated adult rat cardiomyocytes. |
2011-07-14 |
2023-08-12 |
rat |