| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Yang, Y T Zhu, R Cheng, M Y Shao, Z S Fu, L Cheng, F M Wang, T H. Lipopolysaccharide-induced dental pulp cell apoptosis and the expression of Bax and Bcl-2 in vitro. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 43. issue 11. 2011-12-02. PMID:20945038. |
lipopolysaccharide-induced dental pulp cell apoptosis and the expression of bax and bcl-2 in vitro. |
2011-12-02 |
2023-08-12 |
human |
| H Yang, Y T Zhu, R Cheng, M Y Shao, Z S Fu, L Cheng, F M Wang, T H. Lipopolysaccharide-induced dental pulp cell apoptosis and the expression of Bax and Bcl-2 in vitro. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 43. issue 11. 2011-12-02. PMID:20945038. |
we investigated the in vitro effects of lipopolysaccharide on apoptosis of cultured human dental pulp cells and the expression of bcl-2 and bax. |
2011-12-02 |
2023-08-12 |
human |
| H Yang, Y T Zhu, R Cheng, M Y Shao, Z S Fu, L Cheng, F M Wang, T H. Lipopolysaccharide-induced dental pulp cell apoptosis and the expression of Bax and Bcl-2 in vitro. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 43. issue 11. 2011-12-02. PMID:20945038. |
the expression of the apoptosis regulatory proteins bax and bcl-2 was also up-regulated in pulp cells after exposure to a high concentration of lipopolysaccharide. |
2011-12-02 |
2023-08-12 |
human |
| Marvin Rubenstein, Courtney M P Hollowell, Patrick Guina. Effects of BCL-2 suppression by antisense oligonucleotides on additional regulators of apoptosis compensatory change in non-targeted protein expression. In vivo (Athens, Greece). vol 25. issue 5. 2011-11-30. PMID:21753125. |
to identify a compensatory response to evade apoptosis in the presence of bcl-2 suppression, levels of mrna encoding non-targeted bax, caspase-3 and clusterin were evaluated. |
2011-11-30 |
2023-08-12 |
Not clear |
| Marvin Rubenstein, Courtney M P Hollowell, Patrick Guina. Effects of BCL-2 suppression by antisense oligonucleotides on additional regulators of apoptosis compensatory change in non-targeted protein expression. In vivo (Athens, Greece). vol 25. issue 5. 2011-11-30. PMID:21753125. |
we initially found that specific suppression of the apoptosis inhibitor bcl-2 in lncap cells does not affect (non-targeted) bax expression and (non-targeted) caspase-3 expression was suppressed. |
2011-11-30 |
2023-08-12 |
Not clear |
| Vitaliy O Kaminskyy, Olga V Surova, Alena Vaculova, Boris Zhivotovsk. Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL. Carcinogenesis. vol 32. issue 10. 2011-11-29. PMID:21771726. |
the combination of two drugs sensitized sclc cells to trail-induced apoptosis, involving mitochondrial apoptotic pathway and was accompanied by bid cleavage, activation of bax, and release of cytochrome c. both initiator caspase-8 and -9 were required for the sensitization of sclc cells to trail. |
2011-11-29 |
2023-08-12 |
Not clear |
| Jianjie Wang, Qingwang Li, Kun Li, Yetao Ou, Zengsheng Han, Dawei Gao, Jian L. Effects of adenovirus vectors mediated human lactoferrin cDNA on mice bearing EMT6 breast carcinoma. Die Pharmazie. vol 66. issue 9. 2011-11-29. PMID:22026128. |
these data suggest that the antitumor effects of ad-rhltf might be associated with arresting tumor cells in the g0/g1 phase, inducing cell apoptosis and regulation of the expression of bcl-2, bax and activation of caspase 3. |
2011-11-29 |
2023-08-12 |
mouse |
| Qian-Mei Zhou, Xiu-Feng Wang, Xin-Jun Liu, Hui Zhang, Yi-Yu Lu, Shuang Huang, Shi-Bing S. Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects. European journal of cancer (Oxford, England : 1990). vol 47. issue 14. 2011-11-23. PMID:21616659. |
we then investigated the mechanisms associated with mmc/curcumin-induced cell death by examining the effect of mmc/curcumin treatment on apoptosis, the activation of caspase-3, 8 and 9 and the expression of bcl-2 and bax. |
2011-11-23 |
2023-08-12 |
Not clear |
| Takafumi Sai, Yasufumi Goto, Ryousuke Yoshioka, Akihisa Maeda, Fuko Matsuda, Miki Sugimoto, Kannika Wongpanit, Hua-Zi Jin, Jun-You Li, Noboru Manab. Bid and Bax are involved in granulosa cell apoptosis during follicular atresia in porcine ovaries. The Journal of reproduction and development. vol 57. issue 3. 2011-11-22. PMID:21441714. |
bid and bax are involved in granulosa cell apoptosis during follicular atresia in porcine ovaries. |
2011-11-22 |
2023-08-12 |
Not clear |
| Takafumi Sai, Yasufumi Goto, Ryousuke Yoshioka, Akihisa Maeda, Fuko Matsuda, Miki Sugimoto, Kannika Wongpanit, Hua-Zi Jin, Jun-You Li, Noboru Manab. Bid and Bax are involved in granulosa cell apoptosis during follicular atresia in porcine ovaries. The Journal of reproduction and development. vol 57. issue 3. 2011-11-22. PMID:21441714. |
in the present study, we examined changes in the expression of bh3-interacting domain death agonist (bid) and bcl-2-associated x protein (bax), which are considered to promote the cell death ligand/receptor-mediated process in mitochondrion-dependent type ii apoptosis, in porcine granulosa cells during atresia. |
2011-11-22 |
2023-08-12 |
Not clear |
| Ping Xie, Vinay K Kondeti, Sun Lin, Yoshisuke Haruna, Kirtee Raparia, Yashpal S Kanwa. Role of extracellular matrix renal tubulo-interstitial nephritis antigen (TINag) in cell survival utilizing integrin (alpha)vbeta3/focal adhesion kinase (FAK)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B-serine/threonine kinase (AKT) signaling pathway. The Journal of biological chemistry. vol 286. issue 39. 2011-11-22. PMID:21795690. |
transfection of cells with αv-sirna accentuated cisplatin-induced apoptosis, aberrant translocation of cytochrome c and bax, and reduced cell survival. |
2011-11-22 |
2023-08-12 |
rat |
| Yanjie Chen, Takayuki Fujita, Di Zhang, Hung Doan, Decha Pinkaew, Zhihe Liu, Jiaxin Wu, Yuichi Koide, Andrew Chiu, Curtis Chen-Jen Lin, Jui-Yoa Chang, Ke-He Ruan, Ken Fujis. Physical and functional antagonism between tumor suppressor protein p53 and fortilin, an anti-apoptotic protein. The Journal of biological chemistry. vol 286. issue 37. 2011-11-22. PMID:21795694. |
furthermore, cells with wild-type p53 and fortilin, but not cells with wild-type p53 and the double point mutant of fortilin lacking p53 binding, fail to induce bax gene and apoptosis, leading to the formation of large tumor in athymic mice. |
2011-11-22 |
2023-08-12 |
mouse |
| T Hamsa, Girija Kutta. Ipobscurine, an indole alkaloid from Ipomoea obscura, inhibits tumor cell invasion and experimental metastasis by inducing apoptosis. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 30. issue 2. 2011-11-22. PMID:21967460. |
ipobscurine may also promote apoptosis by up-regulating pro-apoptotic molecules such as caspase-3, p53, and bax and by down-regulating anti-apoptotic bcl-2. |
2011-11-22 |
2023-08-12 |
Not clear |
| Yu-Jun Deng, Ning Tan, Hong-Ke Zeng, Yong-Heng Fu, Xiao-Li Don. [Effects of BNP preconditioning on myocardial cell apoptosis and expressions of bcl-2 and Bax during myocardial ischemia-reperfusion injury in rats]. Zhonghua yi xue za zhi. vol 90. issue 48. 2011-11-15. PMID:21223820. |
[effects of bnp preconditioning on myocardial cell apoptosis and expressions of bcl-2 and bax during myocardial ischemia-reperfusion injury in rats]. |
2011-11-15 |
2023-08-12 |
rat |
| Yu-Jun Deng, Ning Tan, Hong-Ke Zeng, Yong-Heng Fu, Xiao-Li Don. [Effects of BNP preconditioning on myocardial cell apoptosis and expressions of bcl-2 and Bax during myocardial ischemia-reperfusion injury in rats]. Zhonghua yi xue za zhi. vol 90. issue 48. 2011-11-15. PMID:21223820. |
to study the effects of b-type natriuretic peptide (bnp) preconditioning on the apoptosis and expressions of bcl-2 and bax in rat cardiomyocytes during myocardial ischemia-reperfusion. |
2011-11-15 |
2023-08-12 |
rat |
| Karol Ondrias, Lubomira Lencesova, Marta Sirova, Martina Labudova, Silvia Pastorekova, Juraj Kopacek, Olga Krizanov. Apoptosis induced clustering of IP(3)R1 in nuclei of non-differentiated PC12 cells. Journal of cellular physiology. vol 226. issue 12. 2011-11-14. PMID:21302308. |
inhibitors of the ip(3) r's calcium release-2-aminoethoxydiphenyl borate (2-apb) and xestospongin-completely prevented bax and caspase-3 mrna increase after treatment with the apoptosis inducer set (aik), and this reinforces the importance of ip(3) r1 in the apoptosis of nd pc12 cells. |
2011-11-14 |
2023-08-12 |
Not clear |
| Qing Wang, Xiao-Hui Yin, Yong Liu, Guang-Yi Zhan. K252a suppresses neuronal cells apoptosis through inhibiting the translocation of Bax to mitochondria induced by the MLK3/JNK signaling after transient global brain ischemia in rat hippocampal CA1 subregion. Journal of receptor and signal transduction research. vol 31. issue 4. 2011-11-14. PMID:21726169. |
k252a suppresses neuronal cells apoptosis through inhibiting the translocation of bax to mitochondria induced by the mlk3/jnk signaling after transient global brain ischemia in rat hippocampal ca1 subregion. |
2011-11-14 |
2023-08-12 |
rat |
| Qing Wang, Xiao-Hui Yin, Yong Liu, Guang-Yi Zhan. K252a suppresses neuronal cells apoptosis through inhibiting the translocation of Bax to mitochondria induced by the MLK3/JNK signaling after transient global brain ischemia in rat hippocampal CA1 subregion. Journal of receptor and signal transduction research. vol 31. issue 4. 2011-11-14. PMID:21726169. |
as a result, through inhibiting phosphorylation of bcl-2 (a cytosolic target of jnk) and 14-3-3 protein (a cytoplasmic anchor of bax) induced by the activation of jnk, k252a decreased the release of bax from bcl-2/bax and 14-3-3/bax dimers, further attenuating the translocation of bax from cytosol to mitochondria and the release of cytochrome c induced by ischemia/reperfusion, which related to mitochondria-mediated apoptosis. |
2011-11-14 |
2023-08-12 |
rat |
| Kwang-Youn Kim, Sun-Nyoung Yu, Sun-Yi Lee, Sung-Sik Chun, Yong-Lark Choi, Yeong-Min Park, Chung Seog Song, Bandana Chatterjee, Soon-Cheol Ah. Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization. Biochemical and biophysical research communications. vol 413. issue 1. 2011-11-14. PMID:21871443. |
salinomycin triggered apoptosis of pc-3 cells by elevating the intracellular ros level, which was accompanied by decreased mitochondrial membrane potential, translocation of bax protein to mitochondria, cytochrome c release to the cytoplasm, activation of the caspase-3 and cleavage of parp-1, a caspase-3 substrate. |
2011-11-14 |
2023-08-12 |
human |
| Emma C Josefsson, Chloé James, Katya J Henley, Marlyse A Debrincat, Kelly L Rogers, Mark R Dowling, Michael J White, Elizabeth A Kruse, Rachael M Lane, Sarah Ellis, Paquita Nurden, Kylie D Mason, Lorraine A O'Reilly, Andrew W Roberts, Donald Metcalf, David C S Huang, Benjamin T Kil. Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets. The Journal of experimental medicine. vol 208. issue 10. 2011-11-14. PMID:21911424. |
to resolve this paradox, we generated mice with hematopoietic- or megakaryocyte-specific deletions of the essential mediators of apoptosis, bak and bax. |
2011-11-14 |
2023-08-12 |
mouse |