| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin Chen, Jun Ma, Hao Che. Induction of autophagy via the ROS-dependent AMPK/mTOR pathway protects deoxynivalenol exposure grass carp hepatocytes damage. Fish & shellfish immunology. 2023-03-15. PMID:36921881. |
furthermore, we discovered that don exposure caused apoptosis, which is characterized by elevated levels of bax, caspase 9, caspase 3, and decreased bcl-2 levels. |
2023-03-15 |
2023-08-14 |
human |
| Enrico Escobar, Fernán Gómez-Valenzuela, Cristian Peñafiel, Eduardo Chimenos-Küstner, Ricardo Pérez-Tomá. Aberrant immunoexpression of p53 tumour-suppressor and Bcl-2 family proteins (Bcl-2 and Bax) in ameloblastomas and odontogenic keratocysts. Journal of clinical and experimental dentistry. vol 15. issue 2. 2023-03-13. PMID:36911151. |
bcl-2-associated protein x (bax) and the tumour suppressor protein p53 collectively promote p53-mediated apoptosis. |
2023-03-13 |
2023-08-14 |
Not clear |
| Renjie Li, Huixian He, Xinxin H. APOC1 promotes the progression of osteosarcoma by binding to MTCH2. Experimental and therapeutic medicine. vol 25. issue 4. 2023-03-13. PMID:36911382. |
apoc1 silencing attenuated cell viability, inhibited proliferation and promoted cell apoptosis, coupled with the decreased bcl-2 expression and increased bax and cleaved-caspase 3 expression. |
2023-03-13 |
2023-08-14 |
Not clear |
| Qi Zhou, Yadong Li, Liya Li, Nianzhe Sun, Hanghao Zhang, Jiahui Jiang, Tao Du, Yan Mo, Alaa Aldeen, Runsha Xiao, Yiting Chen, Shuanglian Wang, Mian Liu, Chengmin Li, Xueping Fen. Radiosensitization of Nasopharyngeal Carcinoma by Graphene Oxide Nanosheets to Reduce Bcl-2 Level. Langmuir : the ACS journal of surfaces and colloids. 2023-03-13. PMID:36913208. |
the synthesized graphene oxide nanosheets inhibited cell proliferation, promoted cell apoptosis, and inhibited the expression of bcl-2 in c666-1 and hk-1 cells but increased the level of bax. |
2023-03-13 |
2023-08-14 |
Not clear |
| Fatemeh Moradian, Sedigheh Mohammadzade. Evaluation of the effect of nano-encapsulated lactoferrin on the expression of Bak and Bax genes in gastric cancer cell line AGS and study of the molecular docking of lactoferrin with these proteins. Gene. 2023-03-12. PMID:36907277. |
in the present study, the effect of different concentrations of nano-encapsulated lactoferrin (ne-lf) on the expression of bax and bak genes was evaluated in stomach cancer cell line ags using real-time pcr technique and cytotoxicity of ne-lf on the growth cells as well as the molecular mechanism of these two genes and their proteins in the apoptosis pathway and the relationship between lactoferrin and these proteins were investigated by bioinformatics studies. |
2023-03-12 |
2023-08-14 |
Not clear |
| Beatriz Linillos-Pradillo, Lisa Rancan, Sergio D Paredes, Margret Schlumpf, Walter Lichtensteiger, Elena Vara, Jesús Á F Tresguerre. Low Dose of BPA Induces Liver Injury through Oxidative Stress, Inflammation and Apoptosis in Long-Evans Lactating Rats and Its Perinatal Effect on Female PND6 Offspring. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902016. |
inducers of oxidative stress (ho-1d, inos, enos), inflammation (il-1β) and apoptosis (aif, bax, bcl-2 and bcl-xl) were measured by qrt-pcr and western blotting in liver of lactating dams and offspring. |
2023-03-11 |
2023-08-14 |
human |
| Y G El-Baz, A Moustafa, M A Ali, G E El-Desoky, S M Wabaidur, M M Faisa. An Analysis of the Toxicity, Antioxidant, and Anti-Cancer Activity of Cinnamon Silver Nanoparticles in Comparison with Extracts and Fractions of Cinnamomum Cassia at Normal and Cancer Cell Levels. Nanomaterials (Basel, Switzerland). vol 13. issue 5. 2023-03-11. PMID:36903823. |
the anti-cancer activity depended on apoptosis marker protein levels (caspase3, p53, bax, and pcl2) in normal and cancerous cells. |
2023-03-11 |
2023-08-14 |
cat |
| Xichi Lin, Chenbiao Li, Shan Xu, Zhouping Wang, Xiaoyuan M. SERS-fluorescence dual-mode nanoprobe for the detection and imaging of Bax mRNA during apoptosis. Mikrochimica acta. vol 190. issue 4. 2023-03-11. PMID:36905455. |
sers-fluorescence dual-mode nanoprobe for the detection and imaging of bax mrna during apoptosis. |
2023-03-11 |
2023-08-14 |
human |
| Xichi Lin, Chenbiao Li, Shan Xu, Zhouping Wang, Xiaoyuan M. SERS-fluorescence dual-mode nanoprobe for the detection and imaging of Bax mRNA during apoptosis. Mikrochimica acta. vol 190. issue 4. 2023-03-11. PMID:36905455. |
bax mrna is one of the key pro-apoptotic factors in the apoptosis pathway. |
2023-03-11 |
2023-08-14 |
human |
| Xichi Lin, Chenbiao Li, Shan Xu, Zhouping Wang, Xiaoyuan M. SERS-fluorescence dual-mode nanoprobe for the detection and imaging of Bax mRNA during apoptosis. Mikrochimica acta. vol 190. issue 4. 2023-03-11. PMID:36905455. |
combined with the high sensitivity of sers and the visualization of fluorescence, this method has good specificity and can be used for in situ imaging and dynamic monitoring of bax mrna during deoxynivalenol (don) toxin-induced apoptosis of hepg2 cells. |
2023-03-11 |
2023-08-14 |
human |
| Zongyu Chen, Shuang He, Siyu Lian, Yi Shen, Wenqing Jiang, Lihua Zhou, Leilei Zhou, Xianming Zhan. The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury. Bioscience reports. vol 43. issue 3. 2023-03-09. PMID:36825682. |
apoptosis of lung tissues was evaluated using tunel, flow cytometry, bax, and bcl2 protein. |
2023-03-09 |
2023-08-16 |
rat |
| Che-Hsueh Yang, Min-Che Tung, Yi-Sheng Lin, Chao-Yu Hsu, Ivan Akhrymuk, Kok-Tong Tan, Yen-Chuan Ou, Chi-Chien Li. Dehydrated Human Amnion-Chorion Membrane Extracts Can Ameliorate Interstitial Cystitis in Rats by Down-Regulating Inflammatory Cytokines and Protein Coding Genes: A Preclinical Study. Life (Basel, Switzerland). vol 12. issue 11. 2023-03-08. PMID:36362848. |
in apoptosis of ic, elevated bax and suppressed bcl-2 were improved (p < 0.05) after instillation. |
2023-03-08 |
2023-08-16 |
human |
| Smita Kapoor, Yogendra S Padwa. Phloretin induces G2/M arrest and apoptosis by suppressing the β-catenin signaling pathway in colorectal carcinoma cells. Apoptosis : an international journal on programmed cell death. 2023-03-08. PMID:36884140. |
moreover, it also induced apoptosis by regulating the expression of bax and bcl-2. |
2023-03-08 |
2023-08-14 |
human |
| Xuechu Wang, Jianping Ji. Magnolol improves Alzheimer's disease-like pathologies and cognitive decline by promoting autophagy through activation of the AMPK/mTOR/ULK1 pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 161. 2023-03-08. PMID:36889111. |
moreover, magnolol inhibited apoptosis by downregulating cleaved-caspase-9 and bax and upregulating bcl-2 in app/ps1 mice and aβo-induced cell models. |
2023-03-08 |
2023-08-14 |
mouse |
| Cihan Gur, Serkan Ali Akarsu, Nurhan Akaras, Sibel Cigdem Tuncer, Fatih Mehmet Kandemi. Carvacrol reduces abnormal and dead sperm counts by attenuating sodium arsenite-induced oxidative stress, inflammation, apoptosis, and autophagy in the testicular tissues of rats. Environmental toxicology. 2023-03-07. PMID:36880177. |
also, car treatment suppressed sa-induced apoptosis by inhibiting bax and caspase-3 expressions in testicles and up-regulating bcl-2 expression. |
2023-03-07 |
2023-08-14 |
rat |
| Pengfei Jiao, Yingrui Wang, Gaofei Ren, Dan Chu, Yameng Li, Tianqing San. Integrating Network Pharmacology and Experimental Validation to Elucidate the Mechanism of Yiqi Yangyin Decoction in Suppressing Non-Small-Cell Lung Cancer. BioMed research international. vol 2023. 2023-03-06. PMID:36874921. |
yyd administration enhanced apoptosis by changing the expression of cleaved caspase-3, bax, and bcl-2. |
2023-03-06 |
2023-08-14 |
mouse |
| Ling Peng, Chunhu Zhang, Gong Xia. Astragalus polysaccharide alleviates angiotensin II-induced glomerular podocyte dysfunction by inhibiting the expression of RARRES1 and LCN2. Clinical and experimental pharmacology & physiology. 2023-03-06. PMID:36876579. |
the expression of rarres1, lipocalin-2 (lcn2), nephrin, and desmin was tested, mpc5 cell viability and apoptosis were evaluated, and the levels of an endocytotic receptor megalin, bcl-2, bax, il-6, il-1β, and tnf-α were assessed. |
2023-03-06 |
2023-08-14 |
mouse |
| Xiaolan Li, Songhua He, Wei Liang, Weiquan Zhang, Xin Chen, Qiaofeng Li, Xin Yang, Yanying Liu, Dan Zhu, Li Li, Buming Liu, Zhiheng Su, Jie Chen, Hongwei Gu. Marsdenia tenacissima injection induces the apoptosis of prostate cancer by regulating the AKT/GSK3β/STAT3 signaling axis. Chinese journal of natural medicines. vol 21. issue 2. 2023-03-05. PMID:36871979. |
in addition, mte induced the apoptosis of du145 cells by reducing the mitochondrial membrane potential and increasing the expression of cleaved caspase 3/7, cyt c, and bax. |
2023-03-05 |
2023-08-14 |
mouse |
| Chunyan Hu, Elena Priceputu, Marc Cool, Pavel Chrobak, Nathalie Bouchard, Clara Forestier, Clifford A Lowell, Serge Bénichou, Zaher Hanna, Virginie Royal, Paul Jolicoeu. NEF-INDUCED HIV-ASSOCIATED NEPHROPATHY THROUGH HCK/LYN. The American journal of pathology. 2023-03-03. PMID:36868467. |
studies of gene-deficient tg mice revealed that the presence of b and t cells and that of several genes was dispensable for the development of hivan: those involved in apoptosis (p53, trail, tnf-α, tnf-r2, bax), in immune cell recruitment (mip-1α, mcp-1, ccr-2, ccr-5 and cx3cr-1), in no formation (enos, inos) or in cell signaling (fyn, lck, hck/fgr). |
2023-03-03 |
2023-08-14 |
mouse |
| Kai Li, Zanjie Feng, Liusong Wang, Xuan Ma, Lei Wang, Kangwei Liu, Xin Geng, Cijun Pen. Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro. Inflammation. 2023-03-01. PMID:36856879. |
furthermore, we found that cga pretreatment reduced hepatocyte apoptosis following hiri, alleviated mitochondrial damage, promoted bcl-2 expression, inhibited bax upregulation, and inhibited cytochrome c release to prevent caspase activation, thereby reducing the expression of the caspase-independent pathway components, endog and aif. |
2023-03-01 |
2023-08-14 |
Not clear |