| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lifan Gu, Yufu Wang, Songlin Xie, Yueran Liu, Jiali Yan, Weixiao Yin, Chaoxi Lu. UvATG6 Interacts with BAX Inhibitor 1 Proteins and Plays Critical Roles in Growth, Conidiation, and Virulence in Microbiology spectrum. 2023-04-27. PMID:37102873. |
uvatg6 interacts with bax inhibitor 1 proteins and plays critical roles in growth, conidiation, and virulence in autophagy and apoptosis are evolutionarily conserved catabolic processes involved in regulating development and cellular homeostasis. |
2023-04-27 |
2023-08-14 |
Not clear |
| Lin Yang, Qiuling Zhao, Ting Chen, Wenbin Liu, Xiuliang Qiu, Jincan Chen, Shengqiang Huang, Ruyi Huang, Liangliang Don. An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma. Clinical and experimental medicine. 2023-04-27. PMID:37106265. |
hpk1 inhibitor treatment increased pd-1, pd-l1, bax, p53 and nk-kb expression but decreased nlrp3 expression, indicating that the hpk1 inhibitor promoted apoptosis and blocked the nlrp3 inflammasome pathway to affect anti-pd-1-mediated t-cell cytotoxicity. |
2023-04-27 |
2023-08-14 |
zebrafish |
| Yilong Zhang, Changbai Che. Knockdown of lncRNA NKILA suppresses sevoflurane-induced neuronal cell injury partially by targeting miR-205-5p/ELAVL1 axis. General physiology and biophysics. vol 42. issue 3. 2023-04-26. PMID:37098737. |
consequently, sev reduced hcn viability and levels of bcl-2, sod, and gsh in hcn, and promoted hcn apoptosis rate and levels of cleaved-caspase-3, bax, mda, tnf-α, il-6, and il-1β. |
2023-04-26 |
2023-08-14 |
human |
| Safieh Ebrahimi, Farshad Mirzavi, Seyed Isaac Hashemy, Maryam Khaleghi Ghadiri, Walter Stummer, Ali Gorj. The in vitro anti-cancer synergy of neurokinin-1 receptor antagonist, aprepitant, and 5-aminolevulinic acid in glioblastoma. BioFactors (Oxford, England). 2023-04-24. PMID:37092793. |
moreover, aprepitant and 5-ala induced apoptosis and altered the levels of apoptotic genes (up-regulation of bax and p53 along with downregulation of bcl-2). |
2023-04-24 |
2023-08-14 |
human |
| Zhanhang Wang, Yonglong He, Shujuan Liu, Xiaolong Xu, Yuxuan Song, Lei Zhang, Xiaopeng A. Toxic effects of zinc oxide nanoparticles as a food additive in goat mammary epithelial cells. Food research international (Ottawa, Ont.). vol 167. 2023-04-22. PMID:37087259. |
moreover, the expression levels of bax, cytc, caspase 3 and caspase 9 were upregulated, while the expression levels of bcl2 were downregulated, which indicated mitochondria-mediated intrinsic apoptosis pathway was activated. |
2023-04-22 |
2023-08-14 |
Not clear |
| Yunjing Li, Menghao Guo, Shuyan Niu, Mengting Shang, Xiaoru Chang, Zuoyi Sun, Rui Zhang, Xin Shen, Yuying Xu. ROS and DRP1 interactions accelerate the mitochondrial injury induced by polystyrene nanoplastics in human liver HepG2 cells. Chemico-biological interactions. 2023-04-21. PMID:37084995. |
the ps-nps treatment could further spark cell apoptosis by upregulating caspase 3, caspase 9, cytochrome c, and bcl-2 associated x protein (bax)/b-cell lymphoma-2 (bcl-2) in hepg2 cells, which is related to the mitochondrial dysfunction. |
2023-04-21 |
2023-08-14 |
human |
| Leila Parsa, Rouhollah Motafakkerazad, Sarvin Taleb Soheyli, Amin Haratian, Morteza Kosari-Nasab, Majid Mahdav. Silymarin in combination with ATRA enhances apoptosis induction in human acute promyelocytic NB4 cells. Toxicon : official journal of the International Society on Toxinology. 2023-04-21. PMID:37085055. |
the real-time pcr illustrated that sm targets apoptosis by down-regulation in survivin and bcl-2 while up-regulation in bax. |
2023-04-21 |
2023-08-14 |
human |
| Lin Xu, Daiting Liu, Xun Wan. LINC00562 drives gastric cancer development by regulating miR-4636-AP1S3 axis. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 27. issue 3. 2023-04-20. PMID:37078294. |
the apoptosis of gc cells was assessed by measuring the expression levels of apoptosis-related proteins (bax and bcl-2). |
2023-04-20 |
2023-08-14 |
mouse |
| Lei Chen, Ke Zhuan. Kaempferol counteracts bupivacaine-induced neurotoxicity in mouse dorsal root ganglia neurons by regulating TRAF6-dependent NF-κB signaling. The Kaohsiung journal of medical sciences. 2023-04-20. PMID:37078471. |
besides, bu-triggered drg neuron apoptosis, and changes in bax and bcl-2 levels were attenuated by ka treatment. |
2023-04-20 |
2023-08-14 |
mouse |
| Long Pei, Xiaosen Song, Xiangdong Liang, Ming Li, Aili Zhang, Xiaoliang Ta. Circular RNA Dipeptidyl Peptidase 4 (circDPP4) Stimulates the Expression of Glutamate Dehydrogenase 1 to Contribute to the Malignant Phenotypes of Prostate Cancer by Sponging miR-497-5p. Molecular biotechnology. 2023-04-20. PMID:37079266. |
levels of circdpp4, microrna (mir)-497-5p, glutamate dehydrogenase 1 (glud1), proliferating cell nuclear antigen (pcna), bcl2 associated x, apoptosis regulator (bax), e-cadherin and ki67 were gauged by a quantitative real-time polymerase chain reaction (qrt-pcr), western blotting, or immunohistochemical method. |
2023-04-20 |
2023-08-14 |
Not clear |
| Gözde Özge Önder, Özge Göktepe, Münevver Baran, Nazmiye Bitgen, Funda Aydin, Arzu Ya. Therapeutic potential of hesperidin: Apoptosis induction in breast cancer cell lines. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-04-20. PMID:37080525. |
cell cycle analysis of hesperidin-treated cells was then performed, as well as immunocytochemical analysis of the effect on the apoptosis pathway (tunel, bax, and bcl-2 expression). |
2023-04-20 |
2023-08-14 |
Not clear |
| Gözde Özge Önder, Özge Göktepe, Münevver Baran, Nazmiye Bitgen, Funda Aydin, Arzu Ya. Therapeutic potential of hesperidin: Apoptosis induction in breast cancer cell lines. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-04-20. PMID:37080525. |
moreover, hesperidin induced cellular apoptosis in mcf-7 breast cancer cells by inhibiting bcl-2 and enhancing bax expression at protein levels. |
2023-04-20 |
2023-08-14 |
Not clear |
| Gözde Özge Önder, Özge Göktepe, Münevver Baran, Nazmiye Bitgen, Funda Aydin, Arzu Ya. Therapeutic potential of hesperidin: Apoptosis induction in breast cancer cell lines. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-04-20. PMID:37080525. |
in addition, hesperidin could significantly stimulate the death mechanisms in er/pr (+) mcf-7 cells by changing the expression balance of bax and bcl-2 proteins, but lead er/pr (-) mda-mb-231 breast cancer cells to apoptosis in a different way. |
2023-04-20 |
2023-08-14 |
Not clear |
| Huiqiong Deng, Wenying Chen, Boyang Zhang, Yiwen Zhang, Lingyun Han, Qipeng Zhang, Song Yao, Hongwei Wang, Xiao Li She. Excessive ER-phagy contributes to ochratoxin A-induced apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-04-20. PMID:37080527. |
a 24 h-treatment of 1-4 μm ota could markedly induce apoptosis via increasing the protein expressions of grp78, p-eif2α, chop, lc3b-ii, bak, and bax, and inhibiting the protein expressions of ddrgk1, uba5, lonp1, tex264, fam134b, p-mtor, p62, and bcl-2 in hk-2 cells (p < 0.05). |
2023-04-20 |
2023-08-14 |
human |
| Zhongqiu Tan, Lifeng Zhao, Shiqing Huang, Qiulan Jiang, Yantao Wei, Junyun Long Wu, Zhiwen Zhang, Yepeng L. Small peptide LINC00511-133aa encoded by LINC00511 regulates breast cancer cell invasion and stemness through the Wnt/β-catenin pathway. Molecular and cellular probes. 2023-04-17. PMID:37068562. |
results showed that linc00511-133aa was indeed encoded by linc00511 and promoted the invasiveness and stemness of breast cancer cells while limiting apoptosis by modulating the expression levels of wnt/β-catenin pathway-related proteins bax, c-myc, and cyclind1, as well as facilitating β-catenin protein entry into the nucleus. |
2023-04-17 |
2023-08-14 |
Not clear |
| Yuehao Tan, Can Li, Jiali Zhou, Fengmei Deng, Yilun Li. Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis. Experimental cell research. 2023-04-16. PMID:37062521. |
bbr also markedly induced hsc apoptosis, as indicated by the upregulated expression of the pro-apoptosis markers p53, bax, and cleaved parp and the downregulated expression of the anti-apoptosis marker bcl-2, effects that were reversed by atg5 overexpression. |
2023-04-16 |
2023-08-14 |
mouse |
| Haibo Gong, Chengmei Zhang, Wei Cao, Shanshan Yao, Xin Chang, Zhiying Miao, Ye Qian, Haijing Den. [Expression of HSP27 and BAX/BCL-2 apoptosis factor in silicosis rat model of fibrosis]. Wei sheng yan jiu = Journal of hygiene research. vol 52. issue 2. 2023-04-16. PMID:37062688. |
to study the expression of heat shock protein 27(hsp27), bax and bcl-2 apoptosis in silicosis rat model, and to explore the correlation between hsp27 and bax and bcl-2 apoptosis. |
2023-04-16 |
2023-08-14 |
rat |
| Masumeh Sanaei, Fraidoon Kavoosi, Mohsen Safar. Effect of 5'-Fluoro-2'-Deoxycytidine and Sodium Butyrate on the Gene Expression of the Intrinsic Apoptotic Pathway, p21, p27, and p53 Genes Expression, Cell Viability, and Apoptosis in Human Hepatocellular Carcinoma Cell Lines. Advanced biomedical research. vol 12. 2023-04-14. PMID:37057236. |
this study aimed to investigate the effect of 5'-fluoro-2'-deoxycytidine (fdcyd) and sodium butyrate on the genes of intrinsic apoptotic pathway (bax, bak and apaf1, bcl-2, and bcl-xl), p21, p27, and p53 gene expression, cell viability, and apoptosis in human hepatocellular carcinoma hep3b, smmc-7721, and ha22t/vgh cell lines. |
2023-04-14 |
2023-08-14 |
human |
| Yu-Feng Wan, Chen-Yu Zhang, Xiao-Wen Cheng, Long-Sheng Liu, Tao Zhou, Jun-Kang Gao, Hua-Qing Zhu, Ye-Hai Li. USP9X expression is functionally related to laryngeal cancer. Journal of Cancer. vol 14. issue 4. 2023-04-14. PMID:37057289. |
we speculated that inhibiting usp9x might induce apoptosis in fadu cells by downregulating mcl-1 and upregulating bax protein expression. |
2023-04-14 |
2023-08-14 |
Not clear |
| Barbora Loncová, Zuzana Fabová, Alexander V Sirotki. Role of kisspeptin-10 and betacellulin in control of feline ovarian cell functions. Reproductive biology. vol 23. issue 2. 2023-04-14. PMID:37058773. |
viability, proliferation (accumulation of cyclin b1) and apoptosis (accumulation of bax), and the release of steroid hormones (progesterone, testosterone, and estradiol) were analyzed by using the trypan blue exclusion test, quantitative immunocytochemistry, and elisa. |
2023-04-14 |
2023-08-14 |
Not clear |