| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dao-Jun Hong, Ai-Lin Pei, Feng-Yan Sun, Cui-Qing Zh. [Aberrant neuronal expression of mitotic protein, tau and Bax in the rat brain after injection of Abeta(25-35) into the amygdala]. Sheng li xue bao : [Acta physiologica Sinica]. vol 55. issue 2. 2012-08-16. PMID:12715101. |
results showed that the levels of neurofibrillary tangle (nft) related phosphorylated tau protein and apoptosis related protein bax were increased in abeta(25-35) injected rat brains, meanwhile the aberrantly expression of mitotic protein cyclin a and cyclin b1 was also detected at 7 d after operation, but the level of cyclin a decreased and cyclin b1 disappeared at 21 d. immunofluorescence double labeling presented that cyclin b1 was partially co-localized with bax or phosphorylated tau protein, whereas bax and phosphorylated tau protein seldom co-localized. |
2012-08-16 |
2023-08-12 |
rat |
| Ying Jiang, Kaimin Rao, Guangtao Yang, Xi Chen, Qian Wang, Ailin Liu, Hongyan Zheng, Jing Yua. Benzo(a)pyrene induces p73 mRNA expression and necrosis in human lung adenocarcinoma H1299 cells. Environmental toxicology. vol 27. issue 4. 2012-08-14. PMID:20862736. |
in this study, normal fetal lung fibroblasts (mrc-5) and human lung adenocarcinoma cells (h1299, p53-null) were treated with bap at concentrations of 8, 16, 32, 64, and 128 μm for 4 and 12 h. the oxidative stress status, extent of dna damage, expression of p53, p73, mdm2, bcl-2, and bax at the mrna and protein levels, and the percentages of apoptosis and/or necrosis were assessed. |
2012-08-14 |
2023-08-12 |
human |
| E D Bazhanov. [Apoptosis of the hypothalamus neurosecretory cells in stress and ageing: the role of immune modulators]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 98. issue 4. 2012-08-14. PMID:22834344. |
we determined the expression of apoptosis markers (bcl-2, mcl-1, bax) in comparison with apoptosis level. |
2012-08-14 |
2023-08-12 |
mouse |
| Yan Li, An-zhou Xia, Shu-hua Xin. Protective effect of edaravone against renal ischemia/reperfusion injury and compared with ischemic postconditioning in rats. Yao xue xue bao = Acta pharmaceutica Sinica. vol 45. issue 7. 2012-08-13. PMID:20931780. |
tunel staining was performed to analyze the apoptosis of the tubular epithelial cells, the protein level of bcl-2 and bax in renal tissue was examined by western blotting. |
2012-08-13 |
2023-08-12 |
rat |
| Hongbo Min, Gautam S Ghatnekar, Angela V Ghatnekar, Xiaohong You, Min Bu, Xinyi Guo, Shizhong Bu, Bo Shen, Qin Huan. 2-Methoxyestradiol induced Bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation. Molecular carcinogenesis. vol 51. issue 7. 2012-08-13. PMID:21769948. |
2-methoxyestradiol induced bax phosphorylation and apoptosis in human retinoblastoma cells via p38 mapk activation. |
2012-08-13 |
2023-08-12 |
human |
| Hongbo Min, Gautam S Ghatnekar, Angela V Ghatnekar, Xiaohong You, Min Bu, Xinyi Guo, Shizhong Bu, Bo Shen, Qin Huan. 2-Methoxyestradiol induced Bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation. Molecular carcinogenesis. vol 51. issue 7. 2012-08-13. PMID:21769948. |
furthermore, only transiently transfected mutant baxt167a, but not bax s163a, inhibited 2me-induced apoptosis. |
2012-08-13 |
2023-08-12 |
human |
| Hongbo Min, Gautam S Ghatnekar, Angela V Ghatnekar, Xiaohong You, Min Bu, Xinyi Guo, Shizhong Bu, Bo Shen, Qin Huan. 2-Methoxyestradiol induced Bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation. Molecular carcinogenesis. vol 51. issue 7. 2012-08-13. PMID:21769948. |
in summary, our data suggest that 2me induces apoptosis in human rb cells by causing phosphorylation of p38 mitogen-activated protein kinase (mapk), which appears to be correlated with phosphorlation of bax. |
2012-08-13 |
2023-08-12 |
human |
| Qing Sun, Jun Hua, Qi Wang, Wei Xu, Jiaxing Zhang, Jun Zhang, Jiuhong Kang, Maoquan L. Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer. Molecular biology reports. vol 39. issue 6. 2012-08-13. PMID:22297694. |
expressions of grp78 and bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer. |
2012-08-13 |
2023-08-12 |
human |
| Qing Sun, Jun Hua, Qi Wang, Wei Xu, Jiaxing Zhang, Jun Zhang, Jiuhong Kang, Maoquan L. Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer. Molecular biology reports. vol 39. issue 6. 2012-08-13. PMID:22297694. |
the purpose of this study was to detect the expressions of grp78 and bax in human non-small cell lung cancer (nsclc) tissues, to analyze their correlations with carcinogenesis and the development of nsclc, and to investigate the relationship of grp78 expression to metastasis and apoptosis in the nsclc cell line hcc827. |
2012-08-13 |
2023-08-12 |
human |
| Ying Xu, Lifeng Liu, Xueshan Qiu, Zihui Liu, Haiying Li, Zixuan Li, Wenting Luo, Enhua Wan. CCL21/CCR7 prevents apoptosis via the ERK pathway in human non-small cell lung cancer cells. PloS one. vol 7. issue 3. 2012-08-13. PMID:22438908. |
these results strongly suggest that ccl21/ccr7 prevents apoptosis by upregulating the expression of bcl-2 and by downregulating the expression of bax and caspase-3 potentially via the erk pathway in a549 and h460 cells of nsclc. |
2012-08-13 |
2023-08-12 |
human |
| Seung-Wook Ryu, Kyungsun Choi, Jong-Hwan Park, Yeong-Min Park, Sunchang Kim, Chulhee Cho. Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner. Cancer letters. vol 323. issue 1. 2012-08-13. PMID:22484496. |
when ectopically expressed, mfn1 inhibited the amino-terminal activation, but not the mitochondrial translocation, of bax during staurosporine-induced apoptosis; overexpression of mfn2 had no effect. |
2012-08-13 |
2023-08-12 |
Not clear |
| Jae In Song, Yu Jin Kang, Hae-Young Yong, Young Choong Kim, Aree Moo. Denbinobin, a phenanthrene from dendrobium nobile, inhibits invasion and induces apoptosis in SNU-484 human gastric cancer cells. Oncology reports. vol 27. issue 3. 2012-08-10. PMID:22089965. |
we also provide evidence that denbinobin induces apoptosis through down-regulation of bcl-2 and an up-regulation of bax. |
2012-08-10 |
2023-08-12 |
human |
| Xihai Li, Hongzhi Ye, Liangliang Cai, Fangrong Yu, Wenlie Chen, Ruhui Lin, Chunsong Zheng, Huifeng Xu, Jinxia Ye, Guangwen Wu, Xianxiang Li. Millimeter wave radiation induces apoptosis via affecting the ratio of Bax/Bcl-2 in SW1353 human chondrosarcoma cells. Oncology reports. vol 27. issue 3. 2012-08-10. PMID:22109662. |
the present study was undertaken to examine the effects of millimeter wave radiation on cell apoptosis and mitochondrial membrane potential, and to determine the molecular mechanism of millimeter wave radiation-induced apoptosis by investigating the expression of bcl-2 family proteins (bcl-2, bax), caspase-9 and caspase-3 in sw1353 cells. |
2012-08-10 |
2023-08-12 |
human |
| I Skírnisdóttir, T Seida. The apoptosis regulators p53, bax and PUMA: Relationship and impact on outcome in early stage (FIGO I-II) ovarian carcinoma after post-surgical taxane-based treatment. Oncology reports. vol 27. issue 3. 2012-08-10. PMID:22159712. |
the apoptosis regulators p53, bax and puma: relationship and impact on outcome in early stage (figo i-ii) ovarian carcinoma after post-surgical taxane-based treatment. |
2012-08-10 |
2023-08-12 |
Not clear |
| I Skírnisdóttir, T Seida. The apoptosis regulators p53, bax and PUMA: Relationship and impact on outcome in early stage (FIGO I-II) ovarian carcinoma after post-surgical taxane-based treatment. Oncology reports. vol 27. issue 3. 2012-08-10. PMID:22159712. |
the objective of this study was to evaluate the prognostic effect of the apoptosis regulators p53, bax and puma for recurrent disease and disease-free survival (dfs) in a series of 105 patients in figo-stages i-ii with epithelial ovarian cancer, all treated with post-surgical platinum-taxane chemotherapy. |
2012-08-10 |
2023-08-12 |
Not clear |
| Na Lu, Libin Wei, Dandan Gong, Yuan Gao, Qinsheng Dai, Zhiyu Li, Qinglong Gu. VI-16, a newly synthesized flavonoid, induces apoptosis through the mitochondrial pathway in human hepatoma cells. Oncology reports. vol 27. issue 3. 2012-08-10. PMID:22179765. |
the changes in the expression of caspase-8, capsase-9, bax and bcl-2 after vi-16 treatment suggested that the mitochondrial pathway was involved in the apoptosis induced by vi-16. |
2012-08-10 |
2023-08-12 |
human |
| Igor Sukhotnik, Jorge G Mogilner, Yulia Pollak, Shiri Blumenfeld, Jacob Bejar, Arnold G Cora. PDGF-α stimulates intestinal epithelial cell turnover after massive small bowel resection in a rat. American journal of physiology. Gastrointestinal and liver physiology. vol 302. issue 11. 2012-08-10. PMID:22461028. |
a significant decrease in cell apoptosis in this group was correlated with lower bax protein levels. |
2012-08-10 |
2023-08-12 |
rat |
| Periyasamy Giridharan, Shilpa Amit Verekar, Amit Khanna, P D Mishra, Sunil Kumar Deshmuk. Anticancer activity of sclerotiorin, isolated from an endophytic fungus Cephalotheca faveolata Yaguchi, Nishim. & Udagawa. Indian journal of experimental biology. vol 50. issue 7. 2012-08-09. PMID:22822525. |
in this study sclerotiorin has been found to induce apoptosis in colon cancer (hct-116) cells through the activation of bax, and down-regulation of bcl-2, those further activated cleaved caspase-3 causing apoptosis of cancer cells. |
2012-08-09 |
2023-08-12 |
Not clear |
| Ji-Hong Cui, Qing Qiao, Ying Guo, Ya-Qing Zhang, Hong Cheng, Fu-Rong He, Jing Zhan. Increased apoptosis and expression of FasL, Bax and caspase-3 in human lupus nephritis class II and IV. Journal of nephrology. vol 25. issue 2. 2012-08-07. PMID:21725926. |
increased apoptosis and expression of fasl, bax and caspase-3 in human lupus nephritis class ii and iv. |
2012-08-07 |
2023-08-12 |
human |
| Ji-Hong Cui, Qing Qiao, Ying Guo, Ya-Qing Zhang, Hong Cheng, Fu-Rong He, Jing Zhan. Increased apoptosis and expression of FasL, Bax and caspase-3 in human lupus nephritis class II and IV. Journal of nephrology. vol 25. issue 2. 2012-08-07. PMID:21725926. |
however, the role of renal cellular apoptosis in the pathogenesis and progression of human lupus nephritis (ln) is controversial, and studies on the expression of apoptosis-related proteins, such as fasl, bax and caspase-3, in different classifications of human ln renal tissues are limited. |
2012-08-07 |
2023-08-12 |
human |