| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S-A Quast, A Berger, J Eberl. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis. Cell death & disease. vol 4. 2014-03-12. PMID:24113173. |
ros-dependent phosphorylation of bax by wortmannin sensitizes melanoma cells for trail-induced apoptosis. |
2014-03-12 |
2023-08-12 |
Not clear |
| S-A Quast, A Berger, J Eberl. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis. Cell death & disease. vol 4. 2014-03-12. PMID:24113173. |
the pathways of reactive oxygen species (ros)-mediated apoptosis induction, of bax activation and the sensitization of tumor cells for trail (tnf-related apoptosis-inducing ligand)-induced apoptosis are still largely elusive. |
2014-03-12 |
2023-08-12 |
Not clear |
| S-A Quast, A Berger, J Eberl. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis. Cell death & disease. vol 4. 2014-03-12. PMID:24113173. |
apoptosis was dependent on bax and abrogated by bcl-2 overexpression. |
2014-03-12 |
2023-08-12 |
Not clear |
| S-A Quast, A Berger, J Eberl. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis. Cell death & disease. vol 4. 2014-03-12. PMID:24113173. |
providing the link between ros and bax, we show that abrogated ros production by α-tocopherol or by nadph oxidase 4 (nox4) sirna suppressed apoptosis and bax activation. |
2014-03-12 |
2023-08-12 |
Not clear |
| S-A Quast, A Berger, J Eberl. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis. Cell death & disease. vol 4. 2014-03-12. PMID:24113173. |
the data unraveled a mechanism by which nox4-dependent ros production controls apoptosis via bax phosphorylation. |
2014-03-12 |
2023-08-12 |
Not clear |
| Tomohiro Tanaka, Tomoko Wakabayashi, Hiroaki Oizumi, Shu Nishio, Takashi Sato, Akihiro Harada, Daisuke Fujii, Yuko Matsuo, Tadafumi Hashimoto, Takeshi Iwatsub. CLAC-P/collagen type XXV is required for the intramuscular innervation of motoneurons during neuromuscular development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 4. 2014-03-11. PMID:24453327. |
bax deletion in col25a1 ko mice rescued motoneurons from apoptosis, although motor axons remained halted around the muscle entry site. |
2014-03-11 |
2023-08-12 |
mouse |
| N I Grineva, T V Akhlynina, A M Timofeev, L P Gerasimova, D A Shmarov, N M Naĭdenova, T E Manakova, T G Sarycheva, L G Kovalev. [Apoptosis and neutrophils on the regulation of proliferation and differentiation ex vifo of myeloid cells with Ph-chromosome]. Molekuliarnaia biologiia. vol 47. issue 4. 2014-03-11. PMID:24466754. |
human myeloid cells with ph chromosome (ph+ cells) from chronic myeloid leukemia (cml) in the course of proliferation and differentiation ex vivo are regulated under alternation of cell proliferation and neutrophil maturation stages by consecutive blocking and inducing apoptosis with of neutrophils participation as well bcr/abl, bax and bcl2 genes expression. |
2014-03-11 |
2023-08-12 |
human |
| N I Grineva, T V Akhlynina, A M Timofeev, L P Gerasimova, D A Shmarov, N M Naĭdenova, T E Manakova, T G Sarycheva, L G Kovalev. [Apoptosis and neutrophils on the regulation of proliferation and differentiation ex vifo of myeloid cells with Ph-chromosome]. Molekuliarnaia biologiia. vol 47. issue 4. 2014-03-11. PMID:24466754. |
stable apoptosis blocking is accompanied by increasing amounts of blasts and myelocytes and enhancing bcr/abl and bcl 2 > bax expression. |
2014-03-11 |
2023-08-12 |
human |
| Marcelo Hernández-Salazar, Ramón G Guevara-González, Andrés Cruz-Hernández, Lorenzo Guevara-Olvera, Luis Arturo Bello-Pérez, Eduardo Castaño-Tostado, Guadalupe Loarca-Piñ. Flaxseed (Linum usitatissimum L.) and its total non-digestible fraction influence the expression of genes involved in azoxymethane-induced colon cancer in rats. Plant foods for human nutrition (Dordrecht, Netherlands). vol 68. issue 3. 2014-03-10. PMID:23907590. |
both treatments (flaxseed and tndf) influence the overexpression of genes involved in cell cycle arrest and mitochondrial apoptosis: p53, p21, bcl-2, bax and caspase-3. |
2014-03-10 |
2023-08-12 |
rat |
| Marcelo Hernández-Salazar, Ramón G Guevara-González, Andrés Cruz-Hernández, Lorenzo Guevara-Olvera, Luis Arturo Bello-Pérez, Eduardo Castaño-Tostado, Guadalupe Loarca-Piñ. Flaxseed (Linum usitatissimum L.) and its total non-digestible fraction influence the expression of genes involved in azoxymethane-induced colon cancer in rats. Plant foods for human nutrition (Dordrecht, Netherlands). vol 68. issue 3. 2014-03-10. PMID:23907590. |
in addition, tndf induced mitochondrial apoptosis because the tndf + aom group exhibited the expression of caspase-3, decreased bcl-2 expression and increased bax expression. |
2014-03-10 |
2023-08-12 |
rat |
| K Stephen Suh, Takemi Tanaka, Sreeja Sarojini, Ginah Nightingale, Rajendra Gharbaran, Andrew Pecora, Andre Go. The role of the ubiquitin proteasome system in lymphoma. Critical reviews in oncology/hematology. vol 87. issue 3. 2014-03-06. PMID:23541070. |
these drugs largely interfere with the e1 and e2 regions of the 26s proteasome, blocking proteasomal activity and promoting apoptosis by enhancing activities of the extrinsic (death receptors, trail, fas) and intrinsic (caspases, bax, bcl2, p53, nuclear factor-kappa b, p27) cell death programs. |
2014-03-06 |
2023-08-12 |
Not clear |
| Yan-Xia Ma, Zheng Guo, Tao Su. CGRP inhibits norepinephrine induced apoptosis with restoration of Bcl-2/Bax in cultured cardiomyocytes of rat. Neuroscience letters. vol 549. 2014-03-06. PMID:23714242. |
current study suggests that norepinephrine inhibits synthesis of bcl-2 and increases bax and apoptosis of cardiomyocytes. |
2014-03-06 |
2023-08-12 |
rat |
| Yoon-Jin Lee, David M Lee, Sang-Han Le. Production of Cyr61 protein is modulated by extracellular acidification and PI3K/Akt signaling in prostate carcinoma PC-3 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 58. 2014-03-05. PMID:23623839. |
silencing of cyr61 by sirna induced enhanced activity of caspase-3/7, upregulation of the proapototic bok, biml and bims, cleavage of apoptosis hallmarkers such as bax, parp and caspase-3, and downregulation of antiapoptotic bcl2, bcl-xl and mcl-1 proteins. |
2014-03-05 |
2023-08-12 |
Not clear |
| Lei Zheng, Xiaoli Wang, Wenjuan Luo, Yingzhuan Zhan, Yanmin Zhan. Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 58. 2014-03-05. PMID:23688861. |
in addition, brucine dose-dependently caused lovo cells apoptosis evidenced by annexin v/pi staining brucine-induced apoptosis was mediated via up-regulation of bax and down-regulation of bcl-2. |
2014-03-05 |
2023-08-12 |
Not clear |
| J Tian, Y X Duan, C Y Bei, J Che. Calycosin induces apoptosis by upregulation of RASD1 in human breast cancer cells MCF-7. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 45. issue 8. 2014-03-03. PMID:23609007. |
to provide insight into the functions of rasd1 signaling pathway in calycosin-induced apoptosis, the expression of bcl-2, bax, and rasd1 in calycosin-treated cells were determined by western blot assay. |
2014-03-03 |
2023-08-12 |
human |
| Claudia Fabiola Méndez-Catalá, Svetlana Gretton, Alexander Vostrov, Elena Pugacheva, Dawn Farrar, Yoko Ito, France Docquier, Georgia-Xanthi Kita, Adele Murrell, Victor Lobanenkov, Elena Klenov. A novel mechanism for CTCF in the epigenetic regulation of Bax in breast cancer cells. Neoplasia (New York, N.Y.). vol 15. issue 8. 2014-03-03. PMID:23908591. |
in this context, ctcf functions as a transcriptional repressor counteracting influences of positive regulatory factors; depletion of breast cancer cells from ctcf therefore results in the activation of bax and apoptosis. |
2014-03-03 |
2023-08-12 |
human |
| Venkateshwar Madka, Yuting Zhang, Qian Li, Altaf Mohammed, Puneet Sindhwani, Stan Lightfoot, Xue-Re Wu, Levy Kopelovich, Chinthalapally V Ra. p53-stabilizing agent CP-31398 prevents growth and invasion of urothelial cancer of the bladder in transgenic UPII-SV40T mice. Neoplasia (New York, N.Y.). vol 15. issue 8. 2014-03-03. PMID:23908596. |
molecular analysis of the bladder tumors showed an increase in apoptosis markers (p53, p21, bax, and annexin v) with a decrease in vascular endothelial growth factor in transgenic mice fed cp-31398. |
2014-03-03 |
2023-08-12 |
mouse |
| Songbai Jia, Jingming Shi, Xuan Chen, Luosheng Tan. [Ultraviolet radiation-induced apoptosis in human lens epithelial cells and its effect on Bcl-2 and Bax]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 37. issue 7. 2014-02-27. PMID:22886222. |
[ultraviolet radiation-induced apoptosis in human lens epithelial cells and its effect on bcl-2 and bax]. |
2014-02-27 |
2023-08-12 |
human |
| Jia Du, Xiu-Feng Wang, Qian-Mei Zhou, Tian-Ling Zhang, Yi-Yu Lu, Hui Zhang, Shi-Bing S. Evodiamine induces apoptosis and inhibits metastasis in MDA‑MB-231 human breast cancer cells in vitro and in vivo. Oncology reports. vol 30. issue 2. 2014-02-27. PMID:23708383. |
evodiamine-induced g0/g1 arrest and apoptosis were associated with a decrease in bcl-2, cyclin d1 and cyclin-dependent kinase 6 (cdk6) expression and an increase in bax and p27kip1 expression. |
2014-02-27 |
2023-08-12 |
human |
| Xia Xie, Bo Tang, Jianyun Zhou, Qing Gao, Pengbing Zhan. Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine. Oncology reports. vol 30. issue 2. 2014-02-27. PMID:23743572. |
finally, ly294002 was able to decrease the expression of mdr1/p‑gp, bcl‑2 and xiap, and upregulate expression of bax and caspase‑3, thereby enhancing chemosensitivity to vcr by inhibiting a drug pump and inducing apoptosis. |
2014-02-27 |
2023-08-12 |
human |