| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhan Zhang, Huiyuan Lu, Fei Huan, Cromie Meghan, Xuejiao Yang, Yun Wang, Xichen Wang, Xinru Wang, Shou-Lin Wan. Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. International journal of cancer. vol 134. issue 7. 2014-04-17. PMID:24114584. |
however, the apoptosis of p40 cells was near normal, while the expression of bax, c-caspase 3 and c-parp increased passage-dependently. |
2014-04-17 |
2023-08-12 |
mouse |
| Zhan Zhang, Huiyuan Lu, Fei Huan, Cromie Meghan, Xuejiao Yang, Yun Wang, Xichen Wang, Xinru Wang, Shou-Lin Wan. Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. International journal of cancer. vol 134. issue 7. 2014-04-17. PMID:24114584. |
inhibition of atr (atr sirna or nu6027) reversely increased the apoptosis of p40 b-2a13 cells in parallel with the upregulation of bax, c-caspase 3 and c-parp, suggesting that atr plays an important role in maintaining cell survival via antiapoptosis. |
2014-04-17 |
2023-08-12 |
mouse |
| Andrew W Taylo. Alpha-melanocyte stimulating hormone (α-MSH) is a post-caspase suppressor of apoptosis in RAW 264.7 macrophages. PloS one. vol 8. issue 8. 2014-04-16. PMID:24009773. |
since there is little know about α-msh as an anti-apoptotic factor, the effects of α-msh on caspase activity, mitochondrial membrane potential, bcl2 to bax expression, along with tunel staining, and annexin v binding were examined in raw 264.7 macrophages under serum-starved conditions that trigger apoptosis. |
2014-04-16 |
2023-08-12 |
Not clear |
| Feng Zhang, Zhiyi Zhang, Zhiyu Li. Effects of Huaier aqueous extract on proliferation and apoptosis in the melanoma cell line A875. Acta histochemica. vol 115. issue 7. 2014-04-15. PMID:23601357. |
down-regulation of bcl-2 and up-regulation of bcl2-associated x protein (bax) indicated that huaier extract induced apoptosis through the mitochondrial pathway. |
2014-04-15 |
2023-08-12 |
Not clear |
| Yuling Mi, Longlong Tu, Huimin Wang, Weidong Zeng, Caiqiao Zhan. Supplementation with quercetin attenuates 4-nitrophenol-induced testicular toxicity in adult male mice. Anatomical record (Hoboken, N.J. : 2007). vol 296. issue 10. 2014-04-15. PMID:23997041. |
moreover, pnp treatment induced germ cell apoptosis, inhibited bcl-xl expression, and then activated bax expression and the caspase-3 enzyme. |
2014-04-15 |
2023-08-12 |
mouse |
| Yuling Mi, Longlong Tu, Huimin Wang, Weidong Zeng, Caiqiao Zhan. Supplementation with quercetin attenuates 4-nitrophenol-induced testicular toxicity in adult male mice. Anatomical record (Hoboken, N.J. : 2007). vol 296. issue 10. 2014-04-15. PMID:23997041. |
however, simultaneous supplementation with quercetin (75 mg/kg) attenuated the toxicity induced by pnp through renewal of the antioxidant enzyme's status, alleviating apoptosis by regulating the expressions of bax and bcl-xl, xbp-1 and ho-1mrnas, and the regulation of caspase-3 activity. |
2014-04-15 |
2023-08-12 |
mouse |
| Rong Sun, Ke Wang, Dongdong Wu, Xiaoyu Li, Yangbing O. Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway. Folia neuropathologica. vol 50. issue 3. 2014-04-14. PMID:23023341. |
pc12 cells were cultured in vitro, cell viability was assessed by mtt assay, cell apoptosis as well as mitochondrial membrane potential (mmp) were detected by flow cytometric analysis and the expression profiles of apoptosis-related proteins including bcl-2 and bax were investigated by western blot. |
2014-04-14 |
2023-08-12 |
rat |
| Rong Sun, Ke Wang, Dongdong Wu, Xiaoyu Li, Yangbing O. Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway. Folia neuropathologica. vol 50. issue 3. 2014-04-14. PMID:23023341. |
it demonstrated that pf has neuroprotective effect on glutamate-induced apoptosis in pc12 cells via regulating mitochondrial membrane potential and bcl-2/ bax signal pathway. |
2014-04-14 |
2023-08-12 |
rat |
| Zakir Hossain, Tatsuya Sugawara, Takashi Hirat. Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5. Oncology reports. vol 29. issue 3. 2014-04-11. PMID:23291741. |
the expression levels of the apoptosis inducer protein bax were increased by the sphingoid bases from sea cucumber. |
2014-04-11 |
2023-08-12 |
human |
| Zakir Hossain, Tatsuya Sugawara, Takashi Hirat. Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5. Oncology reports. vol 29. issue 3. 2014-04-11. PMID:23291741. |
the results indicate that sphingoid bases from sea cucumber induce apoptosis in hepg2 cells through upregulation of dr5, bax, gadd45 and pparγ and downregulation of p-akt. |
2014-04-11 |
2023-08-12 |
human |
| Fang-Ming Hung, Yung-Liang Chen, An-Cheng Huang, Yu-Ping Hsiao, Jai-Sing Yang, Ming-Teng Chung, Fu-Shin Chueh, Hsu-Feng Lu, Jing-Gung Chun. Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells. Oncology reports. vol 29. issue 3. 2014-04-11. PMID:23314229. |
furthermore, the data also showed that tpl promoted the expression of fas and fasl and increased the activity of caspase-3, -8 and -9, cytochrome c, bax, apoptosis-inducing factor (aif) and endonuclease g (endo g); however, the expression of bax was decreased, leading to apoptosis. |
2014-04-11 |
2023-08-12 |
human |
| Sreevidya Aluvila, Tirtha Mandal, Eric Hustedt, Peter Fajer, Jun Yong Choe, Kyoung Joon O. Organization of the mitochondrial apoptotic BAK pore: oligomerization of the BAK homodimers. The Journal of biological chemistry. vol 289. issue 5. 2014-04-10. PMID:24337568. |
the multidomain pro-apoptotic bcl-2 family proteins bak and bax are believed to form large oligomeric pores in the mitochondrial outer membrane during apoptosis. |
2014-04-10 |
2023-08-12 |
Not clear |
| Yen-Chen Tung, Zheng-Yuan Su, Min-Liang Kuo, Lee-Yan Shee. Ethanolic Extract of Agaricus blazei Fermentation Product Inhibits the Growth and Invasion of Human Hepatoma HA22T/VGH and SK-Hep-1 Cells. Journal of traditional and complementary medicine. vol 2. issue 2. 2014-04-09. PMID:24716127. |
the apoptosis triggered by the ab-pe was regulated by the increased expression of bax, the activation of caspase-3, caspase-9, and parp, and the decreased expression of bcl-2. |
2014-04-09 |
2023-08-13 |
human |
| Liang-ming Liu, Shui-lin Sun, Chang-gen Ye, Dong-yu Liang, Liang Zhao, Fang-ping Yu, Ji-xiang Zhan. [Inhibitive mechanisms of Pim-3 affecting fulminant hepatic apoptosis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 20. issue 9. 2014-04-07. PMID:23207234. |
the pim-3 gene can block fulminant hepatic apoptosis by affecting the expression of the inos liver injury gene and the p53, bax and bcl-2 apoptosis-related genes. |
2014-04-07 |
2023-08-12 |
mouse |
| Lan Luo, Yuhong Li, Yuling Yang, Yongshu He, Yin Wang, Zhongyi Xu, Yan Zhan. Multinucleated cells are involved in normal development and apoptosis in mouse testes. Molecular medicine reports. vol 8. issue 3. 2014-04-07. PMID:23828630. |
increased expression of bax and caspase 3 was detected, revealing that multinucleated cells may be associated with cell apoptosis during testicular development. |
2014-04-07 |
2023-08-12 |
mouse |
| Shiori Kanda, Takeshi Mitsuyasu, Yu Nakao, Shintaro Kawano, Yuichi Goto, Ryota Matsubara, Seiji Nakamur. Anti-apoptotic role of the sonic hedgehog signaling pathway in the proliferation of ameloblastoma. International journal of oncology. vol 43. issue 3. 2014-04-07. PMID:23835807. |
furthermore, in the presence of shh neutralizing antibody, nuclear translocation of gli1 and gli2 was abolished, apoptosis was induced, bcl-2 expression decreased and bax expression increased. |
2014-04-07 |
2023-08-12 |
Not clear |
| Hui Jin, Yu Sun, Shuiying Wang, Xiaodong Chen. Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells. International journal of molecular sciences. vol 14. issue 8. 2014-04-07. PMID:23912239. |
downregulation of phosphor-aktser473 by matrine activated p21 and bax, which contributed to g0/g1 cell cycle and apoptosis. |
2014-04-07 |
2023-08-12 |
Not clear |
| Renjun Peng, Bing Jiang, Jianrong Ma, Zhiming Ma, Xin Wan, Hongwei Liu, Zigui Chen, Quan Cheng, Rui Che. Forced downregulation of RACK1 inhibits glioma development by suppressing Src/Akt signaling activity. Oncology reports. vol 30. issue 5. 2014-04-07. PMID:24008630. |
sirna-induced rack1 downregulation significantly suppressed the proliferation and invasion of human glioma u87 and chg-5 cells, while it promoted their apoptosis by upregulating bax expression and reducing bcl-2 expression. |
2014-04-07 |
2023-08-12 |
mouse |
| Ling Wang, Xinyu Liu, Xianglu Li, Xiao Lv, Kang Lu, Na Chen, Peipei Li, Xin Wan. Arsenic disulfide induces apoptosis of human diffuse large B cell lymphoma cells involving Bax cleavage. Oncology reports. vol 30. issue 5. 2014-04-07. PMID:24026139. |
arsenic disulfide induces apoptosis of human diffuse large b cell lymphoma cells involving bax cleavage. |
2014-04-07 |
2023-08-12 |
human |
| Ling Wang, Xinyu Liu, Xianglu Li, Xiao Lv, Kang Lu, Na Chen, Peipei Li, Xin Wan. Arsenic disulfide induces apoptosis of human diffuse large B cell lymphoma cells involving Bax cleavage. Oncology reports. vol 30. issue 5. 2014-04-07. PMID:24026139. |
the effect was partly due to the induction of mitochondrial-dependent apoptosis involving bax cleavage. |
2014-04-07 |
2023-08-12 |
human |