| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Helen Karlberg, Yee-Joo Tan, Ali Mirazim. Crimean-Congo haemorrhagic fever replication interplays with regulation mechanisms of apoptosis. The Journal of general virology. vol 96. issue Pt 3. 2015-09-30. PMID:25481756. |
most interestingly, we found that cchfv n can suppress induction of apoptosis by bax and inhibit the release of cytochrome c from the inner membrane of mitochondria to cytosol. |
2015-09-30 |
2023-08-13 |
Not clear |
| Jiayi Liang, Qiang Xie, Ping Li, Xueyun Zhong, Yunxian Che. Mitochondrial estrogen receptor β inhibits cell apoptosis via interaction with Bad in a ligand-independent manner. Molecular and cellular biochemistry. vol 401. issue 1-2. 2015-09-29. PMID:25524600. |
moreover, overexpression of erβ prevented bax activation, cytochrome c release, caspase-3 activation, and parp cleavage during apoptosis. |
2015-09-29 |
2023-08-13 |
Not clear |
| Yi Long Dong, Yan Mei Wang, Hong Ju Yang, Xiao Zhou Yang, Hai Jing Y. Phytoestrogen α-zearalanol exerts antiapoptotic effects in differentiated pc12 cells via oestrogen receptor α. Basic & clinical pharmacology & toxicology. vol 116. issue 2. 2015-09-28. PMID:25052567. |
the present results showed a significant increase in apoptosis in differentiated pc12 cells after a 24-hr exposure to amyloid β-peptide fragment 25-35 (aβ25-35 ), accompanied by decreasing of bcl-2 expression and increasing bax expression, whereas a pre-treatment with α-zal ameliorated these changes induced by aβ25-35 . |
2015-09-28 |
2023-08-13 |
Not clear |
| Huan Wang, Liancheng Zhu, Jian Gao, Zhenhua Hu, Bei Li. Promotive role of recombinant HE4 protein in proliferation and carboplatin resistance in ovarian cancer cells. Oncology reports. vol 33. issue 1. 2015-09-28. PMID:25354091. |
markers of apoptosis (bax and bcl-2) were assessed by western blotting. |
2015-09-28 |
2023-08-13 |
human |
| Syed Faiz Mujtaba, Ashish Dwivedi, Neera Yadav, Ratnasekhar Ch, Hari Narayan Kushwaha, Mohana K R Mudiam, Gajendra Singh, Ratan S Ra. Superoxide mediated photomodification and DNA damage induced apoptosis by Benz(a)anthracene via mitochondrial mediated pathway. Journal of photochemistry and photobiology. B, Biology. vol 142. 2015-09-28. PMID:25528193. |
we propose a p21 regulated apoptosis via expression of bax, and cleaved parp under sunlight exposure. |
2015-09-28 |
2023-08-13 |
Not clear |
| Jin Yu Zhang, Yong Jiang, Tao Lin, Jung Won Kang, Jae Eun Lee, Dong Il Ji. Lysophosphatidic acid improves porcine oocyte maturation and embryo development in vitro. Molecular reproduction and development. vol 82. issue 1. 2015-09-25. PMID:25564987. |
further, blastocyst formation and blastocyst cell number were enhanced and apoptosis was reduced upon lpa treatment of embryos created either by ivf and pa. lpa treatment of blastocysts derived by ivf or pa resulted in increased expression of the anti-apoptotic bcl2l1 gene while reducing expression of the pro-apoptotic genes bax and casp3. |
2015-09-25 |
2023-08-13 |
human |
| Guanhai Dai, Yeling Tong, Xuan Chen, Zeming Ren, Xuhua Ying, Feng Yang, Kequn Cha. Myricanol induces apoptotic cell death and anti-tumor activity in non-small cell lung carcinoma in vivo. International journal of molecular sciences. vol 16. issue 2. 2015-09-25. PMID:25629230. |
tunel assay was applied to determine cellular apoptosis, while ihc test was performed to detect the protein expression levels of bax, bcl-2, vegf, hif-1α, and survivin. |
2015-09-25 |
2023-08-13 |
mouse |
| Ruoyu Pang, Meiping Guan, Zongji Zheng, Yaoming Xu. [Effects of metformin on apoptosis induced by advanced glycation end-products and expressions of caspase-3, Bax and Bcl-2 in human dermal fibroblasts in vitro]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 6. 2015-09-25. PMID:26111693. |
[effects of metformin on apoptosis induced by advanced glycation end-products and expressions of caspase-3, bax and bcl-2 in human dermal fibroblasts in vitro]. |
2015-09-25 |
2023-08-13 |
human |
| Shagun Arora, Simran Tando. DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by Ruta graveolens in human colon cancer cells. Homeopathy : the journal of the Faculty of Homeopathy. vol 104. issue 1. 2015-09-24. PMID:25576270. |
the expression of apoptosis and cell-cycle related regulatory genes assessed by reverse transcriptase-pcr revealed an up-regulation of caspase 9, caspase-3, bax, p21 and p27 expression and down-regulation of bcl-2 expression in treated cells. |
2015-09-24 |
2023-08-13 |
human |
| Carolina Amália Barcellos Silva, Elizabeth Ferreira Martinez, Ana Paula Dias Demasi, Albina Altemani, Jeruza Pinheiro da Silveira Bossonaro, Ney Soares Araújo, Vera Cavalcanti de Araúj. Cellular senescence and autophagy of myoepithelial cells are involved in the progression of in situ areas of carcinoma ex-pleomorphic adenoma to invasive carcinoma. An in vitro model. Journal of cell communication and signaling. vol 9. issue 3. 2015-09-24. PMID:25895748. |
protein expression relating to apoptosis (bax, bcl-2, survivin), autophagy (beclin-1, lc3b) and cellular senescence (p21, p16) was evaluated using indirect immunofluorescence. |
2015-09-24 |
2023-08-13 |
Not clear |
| Weiming He, Yingfu Li, Jingyan Tian, Ning Jiang, Bo Du, Yuping Pen. Optimized mixture of As, Cd and Pb induce mitochondria-mediated apoptosis in C6-glioma via astroglial activation, inflammation and P38-MAPK. American journal of cancer research. vol 5. issue 8. 2015-09-23. PMID:26396915. |
an increase in pro-apoptotic bcl-2-associated-x protein (bax) and decrease in anti-apoptotic bcl2 resulting in a bax/bcl2 ratio > 1.0 validated mitochondrial apoptosis. |
2015-09-23 |
2023-08-13 |
rat |
| F Krania, E Dovolou, C A Rekkas, E K Theodosiadou, I Pappas, G S Amiridi. Effects of addition of tissue-type plasminogen activator in in vitro fertilization medium on bovine embryo development and quality. Reproduction in domestic animals = Zuchthygiene. vol 50. issue 1. 2015-09-22. PMID:25405906. |
significant differences were detected in the expression of genes related to apoptosis and/or cell cycle arrest (bax, bcl2l1, kat2b) between embryos produced in t-pa-modified media and controls, giving an overall notion that the inferior developmental competence of treated embryos may be attributed to apoptotic phenomena induced by t-pa. |
2015-09-22 |
2023-08-13 |
cattle |
| Yang Shen, Linyi Meng, Huajun Sun, Yizhun Zhu, Hongrui Li. Cochinchina momordica seed suppresses proliferation and metastasis in human lung cancer cells by regulating multiple molecular targets. The American journal of Chinese medicine. vol 43. issue 1. 2015-09-21. PMID:25649746. |
ecms-induced apoptosis was accompanied by up-regulation of p53, bax and the down-regulation of bcl-2, pi-3k/akt signal pathway, and resulted in the dissipation of mitochondrial membrane potential (ΔΨm) and sequentially activated caspase-3 cascade. |
2015-09-21 |
2023-08-13 |
human |
| Pei-Pei Li, Wei He, Ping-Fan Yuan, Sha-Sha Song, Jing-Tao Lu, Wei We. Celastrol induces mitochondria-mediated apoptosis in hepatocellular carcinoma Bel-7402 cells. The American journal of Chinese medicine. vol 43. issue 1. 2015-09-21. PMID:25657108. |
it increased apoptosis through the up-regulation of bax and the down-regulation of bcl-2 in bel-7402 cells. |
2015-09-21 |
2023-08-13 |
Not clear |
| Hiroko P Indo, Tsukasa Tomiyoshi, Shigeaki Suenaga, Kazuo Tomita, Hiromi Suzuki, Daisuke Masuda, Masahiro Terada, Noriaki Ishioka, Oleg Gusev, Richard Cornette, Takashi Okuda, Chiaki Mukai, Hideyuki J Majim. MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1. Journal of clinical biochemistry and nutrition. vol 57. issue 2. 2015-09-21. PMID:26388666. |
a quantitative real-time reverse transcription polymerase chain reaction (qrt-pcr) examination was performed for apoptosis related factors (bax, cytc, apaf1, vdac1-3, casp3, casp8, casp9 p53, aif, ant1 and 2, bcl2, mnsod, autophagy related becn and necrosis related cyp-40. |
2015-09-21 |
2023-08-13 |
human |
| Dong-Il Kim, Min-Jung Park, Joo-Hee Choi, Seul-Ki Lim, Hak-Jong Choi, Soo-Hyun Par. Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis. The international journal of biochemistry & cell biology. vol 59. 2015-09-18. PMID:25483438. |
such a decrease generates intracellular ros, which increases er stress-mediated p53 expression, and subsequently causes apoptosis by increasing bax promoter activity. |
2015-09-18 |
2023-08-13 |
human |
| María Clara Carou, Paula Romina Cruzans, Alejandro Maruri, Juan Carlos Stockert, Daniel Marcelo Lombard. Apoptosis in ovarian granulosa cells of cattle: morphological features and clearance by homologous phagocytosis. Acta histochemica. vol 117. issue 1. 2015-09-18. PMID:25511683. |
apoptosis and homologous phagocytosis were confirmed by tunel and immunocytochemistry for bax and active caspase 3. |
2015-09-18 |
2023-08-13 |
cattle |
| Jianhong Yu, Xuehui Sun, Guifeng San. Effects of repeated high dosage of chloral hydrate and pentobarbital sodium anesthesia on hepatocellular system in rats. International journal of clinical and experimental medicine. vol 8. issue 7. 2015-09-18. PMID:26379846. |
moreover, administration of chloral hydrate and pentobarbital sodium could induce certain hepatic apoptosis accompanied by the upregulated bax expression, the downregulated bcl-2 expression and bcl-2/bax ratio, and the increase of caspase-3 activity. |
2015-09-18 |
2023-08-13 |
rat |
| Kimberley J Anderson, Aaron P Russell, Victoria C Folett. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS open bio. vol 5. 2015-09-18. PMID:26380811. |
ndrg2 also attenuated apoptosis by reducing cleavage of parp and caspase 3 and expression of pro-apoptotic bax while enhancing the pro-survival bcl-2 and bcl-xl levels. |
2015-09-18 |
2023-08-13 |
Not clear |
| Jie Feng, Chengbo Meng, Da Xin. Aβ induces PUMA activation: a new mechanism for Aβ-mediated neuronal apoptosis. Neurobiology of aging. vol 36. issue 2. 2015-09-17. PMID:25457551. |
notably, puma contributed to neuronal apoptosis through competitive binding of apoptosis repressor with caspase recruitment domain to activate caspase-8 that cleaved bid into tbid to accelerate bax mitochondrial translocation, revealing a novel pathway of bax activation by puma to mediate aβ-induced neuronal apoptosis. |
2015-09-17 |
2023-08-13 |
mouse |