| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xia Li, Lei Zhao, Liang Yue, Haixiao Liu, Xiangmin Yang, Xinchuan Wang, Yan Lin, Yan Q. Evidence for the protective effects of curcumin against oxyhemoglobin-induced injury in rat cortical neurons. Brain research bulletin. vol 120. 2016-09-30. PMID:26551062. |
neuronal apoptosis was assayed via tunel staining and protein levels of cleaved caspase-3, bax, and bcl-2 were measured by western blot. |
2016-09-30 |
2023-08-13 |
rat |
| Correction: Hydrogen Peroxide-Mediated Cytosolic Acidification Is a Signal for Mitochondrial Translocation of Bax during Drug-Induced Apoptosis of Tumor Cells. Cancer research. vol 76. issue 6. 2016-09-30. PMID:26979792. |
correction: hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of bax during drug-induced apoptosis of tumor cells. |
2016-09-30 |
2023-08-13 |
Not clear |
| X Gai, K Tu, C Li, Z Lu, L R Roberts, X Zhen. Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma. Cell death & disease. vol 6. 2016-09-29. PMID:25855960. |
interestingly, forced expression of pcaf reduced bcl-2 expression, upregulated bax and repressed cell apoptosis. |
2016-09-29 |
2023-08-13 |
Not clear |
| Cristina Moncunill-Massaguer, José Saura-Esteller, Alba Pérez-Perarnau, Claudia Mariela Palmeri, Sonia Núñez-Vázquez, Ana M Cosialls, Diana M González-Gironès, Helena Pomares, Anne Korwitz, Sara Preciado, Fernando Albericio, Rodolfo Lavilla, Gabriel Pons, Thomas Langer, Daniel Iglesias-Serret, Joan Gi. A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation. Oncotarget. vol 6. issue 39. 2016-09-28. PMID:26497683. |
in addition, bax and bak are necessary for fluorizoline-induced cytotoxic effects, thereby proving that apoptosis occurs through the intrinsic pathway. |
2016-09-28 |
2023-08-13 |
Not clear |
| Ashish Kumar, Soma Ghosh, Sudhir Chandn. Evidence for microRNA-31 dependent Bim-Bax interaction preceding mitochondrial Bax translocation during radiation-induced apoptosis. Scientific reports. vol 5. 2016-09-28. PMID:26514984. |
evidence for microrna-31 dependent bim-bax interaction preceding mitochondrial bax translocation during radiation-induced apoptosis. |
2016-09-28 |
2023-08-13 |
Not clear |
| Jiaming Liu, Jing Sun, Fangyan Wang, Xichong Yu, Zongxin Ling, Haixiao Li, Huiqing Zhang, Jiangtao Jin, Wenqian Chen, Mengqi Pang, Junjie Yu, Yiwen He, Jiru X. Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate. BioMed research international. vol 2015. 2016-09-28. PMID:26523278. |
c. butyricum not only increased the levels of bdnf and bcl-2 and decreased level of bax but also induced akt phosphorylation (p-akt) and ultimately reduced neuronal apoptosis. |
2016-09-28 |
2023-08-13 |
mouse |
| Long Wang, Qianxue Chen, Zhibiao Chen, Daofeng Tian, Haitao Xu, Qiang Cai, Baohui Liu, Gang Den. EFEMP2 is upregulated in gliomas and promotes glioma cell proliferation and invasion. International journal of clinical and experimental pathology. vol 8. issue 9. 2016-09-28. PMID:26617746. |
more importantly, efemp2 silencing significantly induced cell apoptosis via increasing the ratio of bax and bcl-2. |
2016-09-28 |
2023-08-13 |
Not clear |
| Ping Wang, Peiguo Wang, Becky Liu, Jing Zhao, Qingsong Pang, Samir G Agrawal, Li Jia, Feng-Ting Li. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget. vol 6. issue 26. 2016-09-27. PMID:26093086. |
dynamin-related protein drp1 is required for bax translocation to mitochondria in response to irradiation-induced apoptosis. |
2016-09-27 |
2023-08-13 |
Not clear |
| Ping Wang, Peiguo Wang, Becky Liu, Jing Zhao, Qingsong Pang, Samir G Agrawal, Li Jia, Feng-Ting Li. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget. vol 6. issue 26. 2016-09-27. PMID:26093086. |
translocation of the pro-apoptotic protein bax from the cytosol to the mitochondria is a crucial step in dna damage-mediated apoptosis, and is also found to be involved in mitochondrial fragmentation. |
2016-09-27 |
2023-08-13 |
Not clear |
| Ping Wang, Peiguo Wang, Becky Liu, Jing Zhao, Qingsong Pang, Samir G Agrawal, Li Jia, Feng-Ting Li. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget. vol 6. issue 26. 2016-09-27. PMID:26093086. |
irradiation-induced cytochrome c release and apoptosis was associated with bax activation, but not mitochondrial fragmentation. |
2016-09-27 |
2023-08-13 |
Not clear |
| Ping Wang, Peiguo Wang, Becky Liu, Jing Zhao, Qingsong Pang, Samir G Agrawal, Li Jia, Feng-Ting Li. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget. vol 6. issue 26. 2016-09-27. PMID:26093086. |
however, drp1 mitochondrial translocation and oligomerization did not require bax, and failed to induce apoptosis in bax deficient diffuse large b-cell lymphoma (dlbcl) cells. |
2016-09-27 |
2023-08-13 |
Not clear |
| Ping Wang, Peiguo Wang, Becky Liu, Jing Zhao, Qingsong Pang, Samir G Agrawal, Li Jia, Feng-Ting Li. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget. vol 6. issue 26. 2016-09-27. PMID:26093086. |
in conclusion, our findings demonstrate for the first time, that drp1 is required for bax mitochondrial translocation, but drp1-induced mitochondrial fragmentation alone is not sufficient to induce apoptosis in dlbcl cells. |
2016-09-27 |
2023-08-13 |
Not clear |
| Richard Ponce-Cusi, Gloria M Cala. Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation. International journal of oncology. vol 48. issue 2. 2016-09-27. PMID:26691280. |
it can be concluded that 5-fu may exert apoptotic activity in breast cancer cells transformed by low doses of ionizing α-particles in vitro regulating genes of ras family and related to apoptosis such as bax, bcl-xl and nf-κb expression. |
2016-09-27 |
2023-08-13 |
mouse |
| Zhiqiang Chen, Jian Wen, Huixiang Ju, Zheng Fan. Magnetic nano-Fe3O4 particles targeted gathering and bio-effects on nude mice loading human hepatoma Bel-7402 cell lines model under external magnetic field exposure in vivo. Electromagnetic biology and medicine. vol 34. issue 4. 2016-09-26. PMID:24856871. |
however, gathered mnps combined with elff treatment prolonged mice survival time and inhibited loading tumor cells proliferation significantly compared to other mice groups (p < 0.05); furthermore, the tumor cells early apoptosis ratio of mice group was significantly higher than other groups (p < 0.05), and elff combined with gathered mnps treatment improved tumor cells early apoptosis associated with bcl group protein expression: bax protein expression was higher than bcl-2 and the combined treatment improved cells heat shock protein-27 (hsp-27) expression which could protect cells avoiding early apoptosis. |
2016-09-26 |
2023-08-13 |
mouse |
| Qun Wang, Ping Zeng, Yuanliang Liu, Ge Wen, Xiuqiong Fu, Xuegang Su. Inhibition of autophagy ameliorates atherogenic inflammation by augmenting apigenin-induced macrophage apoptosis. International immunopharmacology. vol 27. issue 1. 2016-09-26. PMID:25899084. |
results illustrated that autophagy inhibition increased apigenin-induced apoptosis through activation of bax. |
2016-09-26 |
2023-08-13 |
mouse |
| Yun-Jiang Zheng, Wei-Ping Xu, Gang Ding, Yu-Hua Gao, Hai-Rong Wang, Shu-Ming Pa. Expression of HMGB1 in septic serum induces vascular endothelial hyperpermeability. Molecular medicine reports. vol 13. issue 1. 2016-09-26. PMID:26572550. |
this mechanism also appears to involve changes in the activation of bax and bcl‑2, resulting in ec apoptosis. |
2016-09-26 |
2023-08-13 |
Not clear |
| Elsayed I Salim, Afaf D Abd El-Magid, Khalid M Farara, Dina S M Mari. Antitumoral and Antioxidant Potential of Egyptian Propolis Against the PC3 Prostate Cancer Cell Line. Asian Pacific journal of cancer prevention : APJCP. vol 16. issue 17. 2016-09-26. PMID:26625775. |
dna fragmentation assay and semi quantitative rt-pcr analyses for p53 and bax genes showed that eep activated cellular apoptosis and increased the mrna expression levels more than other treatment. |
2016-09-26 |
2023-08-13 |
human |
| Yangyang Pan, Honghong He, Yan Cui, Abdul Rasheed Baloch, Qin Li, Jiangfeng Fan, Junfeng He, Sijiu Y. Recombinant Human Bone Morphogenetic Protein 6 Enhances Oocyte Reprogramming Potential and Subsequent Development of the Cloned Yak Embryos. Cellular reprogramming. vol 17. issue 6. 2016-09-26. PMID:26655079. |
the apoptosis and histone modifications of yak cloned blastocysts were evaluated by detecting the expression of relevant genes and proteins (bax, bcl-2, h3k9ac, h3k18ac, and h3k9me3) using relative quantitative rt-pcr or immunofluorescence. |
2016-09-26 |
2023-08-13 |
human |
| Sorina Nicoleta Petrache Voicu, Diana Dinu, Cornelia Sima, Anca Hermenean, Aurel Ardelean, Elena Codrici, Miruna Silvia Stan, Otilia Zărnescu, Anca Dinischiot. Silica Nanoparticles Induce Oxidative Stress and Autophagy but Not Apoptosis in the MRC-5 Cell Line. International journal of molecular sciences. vol 16. issue 12. 2016-09-26. PMID:26690408. |
similarly, the expression of p53, mdm2 and bcl-2 was significantly decreased for all time intervals, while the expression of bax, a marker for apoptosis, was insignificantly downregulated. |
2016-09-26 |
2023-08-13 |
human |
| Ali A Alshatwi, P Subash-Babu, P Antonisam. Violacein induces apoptosis in human breast cancer cells through up regulation of BAX, p53 and down regulation of MDM2. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 68. issue 1. 2016-09-23. PMID:26521020. |
violacein induces apoptosis in human breast cancer cells through up regulation of bax, p53 and down regulation of mdm2. |
2016-09-23 |
2023-08-13 |
human |