| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yudi Han, Lihai Zhang, Yaling Xing, Licheng Zhang, Xiaojuan Chen, Peifu Tang, Zhongbin Che. Autophagy relieves the function inhibition and apoptosis‑promoting effects on osteoblast induced by glucocorticoid. International journal of molecular medicine. vol 41. issue 2. 2018-07-17. PMID:29207032. |
flow cytometry and western blotting were used for the examination of apoptosis and expression of bax apoptosis regulator (bax)/apoptosis regulator bcl‑2 (bcl‑2). |
2018-07-17 |
2023-08-13 |
Not clear |
| Yudi Han, Lihai Zhang, Yaling Xing, Licheng Zhang, Xiaojuan Chen, Peifu Tang, Zhongbin Che. Autophagy relieves the function inhibition and apoptosis‑promoting effects on osteoblast induced by glucocorticoid. International journal of molecular medicine. vol 41. issue 2. 2018-07-17. PMID:29207032. |
subsequently, flow cytometry was used to demonstrate that inhibition of autophagy induced apoptosis in obs under dex treatment, and was associated with the upregulation of bax and the downregulation of bcl‑2 protein expression. |
2018-07-17 |
2023-08-13 |
Not clear |
| Edward Lu, Sumit Sarkar, James Raymick, Merle G Paule, Qiang G. Decreased Mcl-1 protein level in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. Brain research. vol 1678. 2018-07-16. PMID:29158176. |
in addition, the two proteins bax and erk, both of which are also involved in apoptosis signaling, were examined. |
2018-07-16 |
2023-08-13 |
mouse |
| Hailian Wang, Wei Ge, Wen Jiang, Dong Li, Xiuli J. SRPK1‑siRNA suppresses K562 cell growth and induces apoptosis via the PARP‑caspase3 pathway. Molecular medicine reports. vol 17. issue 1. 2018-07-12. PMID:29138847. |
the roles of caspase‑3, poly (adp‑ribose) polymerase (parp), p53 and b-cell lymphoma (bcl)‑2/bcl‑2 associated x, apoptosis regulator (bax) proteins in the apoptosis of human k562 cells were further examined through western blot analysis. |
2018-07-12 |
2023-08-13 |
human |
| Zenghuang Ma, Xiaojie Xu. Differentially expressed proteins in the human esophageal cancer cell line Eca‑109, in the presence and absence of gemcitabine. Molecular medicine reports. vol 17. issue 1. 2018-07-12. PMID:29138856. |
the differential proteins were verified to be b cell lymphoma‑2 associated x, apoptosis regulator (bax)‑α, apoptosis‑associated speck‑like protein containing a card (asc) and myeloid cell leukemia sequence (mcl)‑1. |
2018-07-12 |
2023-08-13 |
human |
| Dalia I Al-Dosari, Mohammed M Ahmed, Salim S Al-Rejaie, Abdullah S Alhomida, Mohammad S Ol. Flavonoid Naringenin Attenuates Oxidative Stress, Apoptosis and Improves Neurotrophic Effects in the Diabetic Rat Retina. Nutrients. vol 9. issue 10. 2018-07-11. PMID:29064407. |
in addition, naringenin treatment ameliorated the levels of apoptosis regulatory proteins; b cell lymphoma 2 (bcl-2), bcl-2 associated x protein (bax) and caspase-3 in the diabetic retina. |
2018-07-11 |
2023-08-13 |
rat |
| Wei Zhang, Zhiqing Sun, Fanhua Men. Schisandrin B Ameliorates Myocardial Ischemia/Reperfusion Injury Through Attenuation of Endoplasmic Reticulum Stress-Induced Apoptosis. Inflammation. vol 40. issue 6. 2018-07-10. PMID:28748322. |
the apoptosis of heart tissue cells was also tested through the expressions of caspase-9, caspase-3, bcl-2, and bax proteins. |
2018-07-10 |
2023-08-13 |
rat |
| Shuo Yang, Tao Fan, Qi Hu, Weipan Xu, Jian Yang, Changwu Xu, Bofang Zhang, Jing Chen, Hong Jian. Downregulation of microRNA-17-5p improves cardiac function after myocardial infarction via attenuation of apoptosis in endothelial cells. Molecular genetics and genomics : MGG. vol 293. issue 4. 2018-07-10. PMID:29536180. |
western blotting was used to determine the levels of erk, the anti-apoptosis protein bcl-2 and apoptosis proteins, including bax, caspase 3, and caspase 9. |
2018-07-10 |
2023-08-13 |
human |
| Shu-Juan Wang, Wen-Ju Liu, Li-Ke Wang, Xun-Sheng Pang, Li-Guo Yan. The role of Melatonin receptor MTNR1A in the action of Melatonin on bovine granulosa cells. Molecular reproduction and development. vol 84. issue 11. 2018-07-09. PMID:28805353. |
our results indicated that melatonin inhibited gc apoptosis by up-regulating the expression of bcl2, bcl-xl, gpx4, and sod1, and down-regulating the expression of bax, casp3, and tp53. |
2018-07-09 |
2023-08-13 |
cattle |
| Yanhong Cheng, Yingchan Hao, Aimei Zhang, Chaojie Hu, Xiaoxiao Jiang, Quan Wu, Xiucai X. Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib. International journal of molecular medicine. vol 41. issue 1. 2018-07-09. PMID:29115375. |
the p53 protein network regulates important mechanisms in dna damage repair, cell cycle regulation/checkpoints, and cell senescence and apoptosis, as demonstrated by its ability to positively regulate the expression of various pro-apoptotic genes, including b-cell lymphoma-2 (bcl-2) and bcl-2-associated x protein (bax). |
2018-07-09 |
2023-08-13 |
mouse |
| In-Hye Kim, Mi-Jin Kwon, Jae-Hun Jung, Taek-Jeong Na. Protein extracted from Porphyra yezoensis prevents cisplatin-induced nephrotoxicity by downregulating the MAPK and NF-κB pathways. International journal of molecular medicine. vol 41. issue 1. 2018-07-09. PMID:29115386. |
pyp treatment reduced cisplatin‑induced apoptosis and death of hk2 cells by restoring the b‑cell lymphoma‑2 (bcl‑2)‑associated x protein (bax)/bcl‑2 imbalance, cytochrome c release and caspase‑3 activation. |
2018-07-09 |
2023-08-13 |
mouse |
| Zaiheng Zhang, Anmin Jin, Denglu Ya. MicroRNA‑206 contributes to the progression of steroid‑induced avascular necrosis of the femoral head by inducing osteoblast apoptosis by suppressing programmed cell death 4. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115490. |
at the molecular level, overexpression of mir‑206 inhibited the expression of pdcd4, alkaline phosphatase (alp) and b‑cell lymphoma 2 (bcl‑2), and increased the expression of apoptosis regulator bcl2‑x‑associated protein (bax). |
2018-07-09 |
2023-08-13 |
human |
| Hua Huang, Hong Zhang, Dan Li, Shigang Chen, Chanjuan Zhou, Qi Li, Peng He, Liang Fang, Yong Zhang, Xiaomei Li, Jingjing Zhou, Lin Sun, Siwen Liu, Yujie Guo, Ying Huang, Peng Xi. Different inhibitory effects on the proliferation and apoptosis of human and laboratory Borna disease virus‑infected human neuroblastoma SH‑SY5Y cells in vitro. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115502. |
western blot analysis confirmed the upregulation of apoptosis regulator bax protein and the downregulation of apoptosis regulator bcl‑2 protein caused by the two bdv strains. |
2018-07-09 |
2023-08-13 |
human |
| Xiangting Gao, Xincai Zhang, Jun Hu, Xuehua Xu, Yuanyi Zuo, Yun Wang, Jingfeng Ding, Hongfei Xu, Shaohua Zh. Aconitine induces apoptosis in H9c2 cardiac cells via mitochondria‑mediated pathway. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115599. |
taken together, the results indicated that aconitine may inhibit cell viability, decrease pgc‑1α expression, induce mitochondrial dysfunctions, upregulate cytochrome c, bax and caspase‑3, and downregulate bcl‑2, suggesting that aconitine may induce apoptosis through mitochondria‑mediated signaling pathways in h9c2 cells. |
2018-07-09 |
2023-08-13 |
Not clear |
| Jing Wu, Zhihui Sun, Huijie Sun, Yanhua L. MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer. Molecular medicine reports. vol 17. issue 1. 2018-07-09. PMID:29115608. |
a luciferase assay was performed to evaluate the effect of mir‑27a on phosphatase and tensin homolog (pten) and b cell lymphoma (bcl)‑2 associated x, apoptosis regulator (bax) expression. |
2018-07-09 |
2023-08-13 |
mouse |
| Zhiyong Xu, Mingxue Zheng, Li Zhang, Xuesong Zhang, Yan Zhang, Xiaozhen Cui, Xin Gong, Rou Xi, Rui Ba. Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells. BMC veterinary research. vol 13. issue 1. 2018-07-09. PMID:29282063. |
effect of atp and bax on the apoptosis of eimeria tenella host cells. |
2018-07-09 |
2023-08-13 |
Not clear |
| Zhiyong Xu, Mingxue Zheng, Li Zhang, Xuesong Zhang, Yan Zhang, Xiaozhen Cui, Xin Gong, Rou Xi, Rui Ba. Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells. BMC veterinary research. vol 13. issue 1. 2018-07-09. PMID:29282063. |
therefore, it is necessary to investigate the effects of atp and bax on the apoptosis of e. tenella host cells. |
2018-07-09 |
2023-08-13 |
Not clear |
| Jennifer Law, Isabel Kwek, Orysya Svystun, Jonathan Lim, Chong Teik Tan, Le Luong, Victor C Yu, Shairaz Baks. RACK1/TRAF2 regulation of modulator of apoptosis-1 (MOAP-1). Biochimica et biophysica acta. Molecular cell research. vol 1865. issue 5. 2018-07-09. PMID:29470995. |
we have demonstrated that during death receptor-dependent apoptosis, moap-1 is recruited to tnf-r1 or trail-r1, followed by rassf1a and bax association. |
2018-07-09 |
2023-08-13 |
Not clear |
| Jennifer Law, Isabel Kwek, Orysya Svystun, Jonathan Lim, Chong Teik Tan, Le Luong, Victor C Yu, Shairaz Baks. RACK1/TRAF2 regulation of modulator of apoptosis-1 (MOAP-1). Biochimica et biophysica acta. Molecular cell research. vol 1865. issue 5. 2018-07-09. PMID:29470995. |
moap-1/bax association promotes bax conformational change resulting in the translocation of bax into the mitochondrial membrane, mitochondrial membrane insertion and dysregulation resulting in several hallmark events that execute apoptosis. |
2018-07-09 |
2023-08-13 |
Not clear |
| Jennifer Law, Isabel Kwek, Orysya Svystun, Jonathan Lim, Chong Teik Tan, Le Luong, Victor C Yu, Shairaz Baks. RACK1/TRAF2 regulation of modulator of apoptosis-1 (MOAP-1). Biochimica et biophysica acta. Molecular cell research. vol 1865. issue 5. 2018-07-09. PMID:29470995. |
although a role in apoptosis is established, it is currently unknown how moap-1 is regulated and how it links to bax to promote apoptosis. |
2018-07-09 |
2023-08-13 |
Not clear |