| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xian Nan Tang, Zhen Zheng, Midori A Yenar. Bone marrow chimeras in the study of experimental stroke. Translational stroke research. vol 3. issue 3. 2014-01-29. PMID:24323809. |
inflammation is known to contribute to stroke evolution, and poststroke immune responses have been documented to emanate from the brain via microglia. |
2014-01-29 |
2023-08-12 |
Not clear |
| Åsa Persson, Ahmed Osman, Hayde Bolouri, Carina Mallard, H Georg Kuh. Radixin expression in microglia after cortical stroke lesion. Glia. vol 61. issue 5. 2013-12-16. PMID:23440885. |
radixin expression in microglia after cortical stroke lesion. |
2013-12-16 |
2023-08-12 |
Not clear |
| Åsa Persson, Ahmed Osman, Hayde Bolouri, Carina Mallard, H Georg Kuh. Radixin expression in microglia after cortical stroke lesion. Glia. vol 61. issue 5. 2013-12-16. PMID:23440885. |
the specific location of radixin(+) cells in the peri-infarct region and in microglia suggests a role for radixin in microglial activation after stroke. |
2013-12-16 |
2023-08-12 |
Not clear |
| Sonja Johann, Cordian Beye. Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia. The Journal of steroid biochemistry and molecular biology. vol 137. 2013-12-13. PMID:23196064. |
in this article, we strive for a better comprehension of the mutual reaction between these steroid hormones and the two major glial cell types involved in the maintenance of brain homeostasis, astroglia and microglia, during acute traumatic brain injuries such as stroke and hypoxia. |
2013-12-13 |
2023-08-12 |
Not clear |
| Mathias Gelderblom, Melanie Neumann, Peter Ludewig, Christian Bernreuther, Susanne Krasemann, Priyadharshini Arunachalam, Christian Gerloff, Markus Glatzel, Tim Magnu. Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation. PloS one. vol 8. issue 5. 2013-11-22. PMID:23658802. |
microglia are the innate immune cells of the central nervous system and the first immune cells to become activated in stroke. |
2013-11-22 |
2023-08-12 |
mouse |
| Cai Song, Ye Zhang, Yilong Don. Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration. Journal of neuroinflammation. vol 10. 2013-11-05. PMID:23651534. |
in alzheimer's disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (il)-1β. |
2013-11-05 |
2023-08-12 |
Not clear |
| Francisco J Ortega, Jukka Jolkkonen, Manuel J Rodrígue. Microglia is an active player in how glibenclamide improves stroke outcome. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 7. 2013-09-06. PMID:23632971. |
microglia is an active player in how glibenclamide improves stroke outcome. |
2013-09-06 |
2023-08-12 |
Not clear |
| B-S Liu, R Ferreira, S Lively, L C Schlichte. Microglial SK3 and SK4 currents and activation state are modulated by the neuroprotective drug, riluzole. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 8. issue 1. 2013-08-16. PMID:22527636. |
microglia monitor the cns for 'danger' signals after acute injury, such as stroke and trauma, and then undergo complex activation processes. |
2013-08-16 |
2023-08-12 |
rat |
| Umadevi V Wesley, Raghu Vemuganti, Emine R Ayvaci, Robert J Dempse. Galectin-3 enhances angiogenic and migratory potential of microglial cells via modulation of integrin linked kinase signaling. Brain research. vol 1496. 2013-08-12. PMID:23246924. |
taken together, our studies indicate that gal-3 contributes to angiogenesis and microglia migration that may have implications in post stroke repair. |
2013-08-12 |
2023-08-12 |
human |
| María Angeles Arevalo, María Santos-Galindo, Estefanía Acaz-Fonseca, Iñigo Azcoitia, Luis M Garcia-Segur. Gonadal hormones and the control of reactive gliosis. Hormones and behavior. vol 63. issue 2. 2013-07-19. PMID:22401743. |
activation of astrocytes and microglia after acute neural insults, such as stroke or traumatic cns injury, is considered to be an adaptive response that contributes to minimize neuronal damage. |
2013-07-19 |
2023-08-12 |
Not clear |
| Marcelo M Cardoso, Edna C S Franco, Celice C de Souza, Michelle C da Silva, Amauri Gouveia, Walace Gomes-Lea. Minocycline treatment and bone marrow mononuclear cell transplantation after endothelin-1 induced striatal ischemia. Inflammation. vol 36. issue 1. 2013-07-03. PMID:22945281. |
we explored whether the modulation of microglia activation with minocycline is beneficial to the therapeutic actions of bone marrow mononuclear cells (bmmcs) transplanted after experimental stroke. |
2013-07-03 |
2023-08-12 |
rat |
| Rachael L Terry, Daniel R Getts, Celine Deffrasnes, Caryn van Vreden, Iain L Campbell, Nicholas J C Kin. Inflammatory monocytes and the pathogenesis of viral encephalitis. Journal of neuroinflammation. vol 9. 2013-07-01. PMID:23244217. |
ly6chi/ccr2(hi) inflammatory monocytes have been identified as the circulating precursors of brain macrophages, dendritic cells and arguably microglia in experimental autoimmune encephalomyelitis; alzheimer's disease; stroke; and more recently in cns infection caused by herpes simplex virus, murine hepatitis virus, theiler's murine encephalomyelitis virus, japanese encephalitis virus and west nile virus. |
2013-07-01 |
2023-08-12 |
human |
| Ivan Bohacek, Pierre Cordeau, Mélanie Lalancette-Hébert, Dunja Gorup, Yuan-Cheng Weng, Srecko Gajovic, Jasna Kri. Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury. Journal of neuroinflammation. vol 9. 2013-06-17. PMID:22873409. |
using a live imaging approach, we have previously shown that microglia activation after stroke is characterized by marked and long-term induction of the toll-like receptor (tlr) 2 biophotonic signals. |
2013-06-17 |
2023-08-12 |
Not clear |
| Rubén Martín, Claudia Cordova, Maria L Niet. Secreted phospholipase A2-IIA-induced a phenotype of activated microglia in BV-2 cells requires epidermal growth factor receptor transactivation and proHB-EGF shedding. Journal of neuroinflammation. vol 9. 2013-04-19. PMID:22747893. |
activation of microglia, the primary component of the innate immune response in the brain, is a hallmark of neuroinflammation in neurodegenerative disorders, including alzheimer's disease (ad) and other pathological conditions such as stroke or cns infection. |
2013-04-19 |
2023-08-12 |
Not clear |
| Karsten Ruscher, Ana R Inácio, Kristian Valind, Arman Rowshan Ravan, Enida Kuric, Tadeusz Wieloc. Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. PloS one. vol 7. issue 9. 2013-02-26. PMID:23028794. |
activation of the sigma-1 receptor (sig-1r) improves functional recovery in models of experimental stroke and is known to modulate microglia function. |
2013-02-26 |
2023-08-12 |
rat |
| Edna C S Franco, Marcelo M Cardoso, Amauri Gouvêia, Antonio Pereira, Walace Gomes-Lea. Modulation of microglial activation enhances neuroprotection and functional recovery derived from bone marrow mononuclear cell transplantation after cortical ischemia. Neuroscience research. vol 73. issue 2. 2013-02-19. PMID:22465414. |
activated microglia may exacerbate damage in neural disorders; however, it is unknown how they affect stem cells transplanted after stroke. |
2013-02-19 |
2023-08-12 |
rat |
| Claudia A McCarthy, Antony Vinh, Brad R S Broughton, Christopher G Sobey, Jennifer K Callaway, Robert E Widdo. Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats. Hypertension (Dallas, Tex. : 1979). vol 60. issue 6. 2013-02-07. PMID:23090772. |
furthermore, we have demonstrated that at(2)r stimulation after stroke increased neuronal survival, decreased apoptosis, and caused an increase in the number of activated microglia in the core region of damage. |
2013-02-07 |
2023-08-12 |
rat |
| Jonas Hannestad, Jean-Dominique Gallezot, Thomas Schafbauer, Keunpoong Lim, Tracy Kloczynski, Evan D Morris, Richard E Carson, Yu-Shin Ding, Kelly P Cosgrov. Endotoxin-induced systemic inflammation activates microglia: [¹¹C]PBR28 positron emission tomography in nonhuman primates. NeuroImage. vol 63. issue 1. 2013-01-29. PMID:22776451. |
an important clinical question is whether the effects of systemic inflammation on microglia mediate the deleterious effects of systemic inflammation in diseases such as alzheimer's dementia, multiple sclerosis, and stroke. |
2013-01-29 |
2023-08-12 |
Not clear |
| Balázs Gulyás, Miklós Tóth, Martin Schain, Anu Airaksinen, Adám Vas, Konstantinos Kostulas, Per Lindström, Jan Hillert, Christer Halldi. Evolution of microglial activation in ischaemic core and peri-infarct regions after stroke: a PET study with the TSPO molecular imaging biomarker [((11))C]vinpocetine. Journal of the neurological sciences. vol 320. issue 1-2. 2013-01-14. PMID:22841414. |
already a week after stroke there was an increased radioligand uptake, indicating the up-regulation of tspo and the presence of activated microglia, in both the ischaemic core and the peri-infarct zone. |
2013-01-14 |
2023-08-12 |
Not clear |
| D Fernández-López, J Faustino, N Derugin, M Wendland, I Lizasoain, M A Moro, Z S Vexle. Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke. Neuroscience. vol 207. 2012-11-27. PMID:22285309. |
reduced infarct size and accumulation of microglia in rats treated with win 55,212-2 after neonatal stroke. |
2012-11-27 |
2023-08-12 |
rat |