| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Corinne Benakis, Lidia Garcia-Bonilla, Costantino Iadecola, Josef Anrathe. The role of microglia and myeloid immune cells in acute cerebral ischemia. Frontiers in cellular neuroscience. vol 8. 2015-02-02. PMID:25642168. |
in this review we aim to summarize recent literature concerning the origins, fate and role of microglia, monocytes and neutrophils in models of cerebral ischemia and to discuss their relevance for human stroke. |
2015-02-02 |
2023-08-13 |
human |
| Rajkumar Verma, Brett D Friedler, Nia M Harris, Louise D McCulloug. Pair housing reverses post-stroke depressive behavior in mice. Behavioural brain research. vol 269. 2015-01-15. PMID:24793492. |
however, a more detailed assessment of cellular expression showed a significant increase in the number of microglia that co-labeled with arginase-1 in the peri-infarct region in ph stroke mice compared to si mice. |
2015-01-15 |
2023-08-13 |
mouse |
| Y Chen, S J Won, Y Xu, R A Swanso. Targeting microglial activation in stroke therapy: pharmacological tools and gender effects. Current medicinal chemistry. vol 21. issue 19. 2015-01-09. PMID:24372213. |
microglia are the resident immune cells of the central nervous system, and they respond to stroke by assuming an activated phenotype that releases cytotoxic cytokines, reactive oxygen species, proteases, and other factors. |
2015-01-09 |
2023-08-12 |
Not clear |
| Kana Sugimoto, Ryutaro Nishioka, Airi Ikeda, Ayano Mise, Hisaaki Takahashi, Hajime Yano, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanak. Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-β1. Glia. vol 62. issue 2. 2014-09-26. PMID:24311432. |
activated microglia in a rat stroke model express ng2 proteoglycan in peri-infarct tissue through the involvement of tgf-β1. |
2014-09-26 |
2023-08-12 |
rat |
| Francisco J Ortega, Jana Vukovic, Manuel J Rodríguez, Perry F Bartlet. Blockade of microglial KATP -channel abrogates suppression of inflammatory-mediated inhibition of neural precursor cells. Glia. vol 62. issue 2. 2014-09-26. PMID:24311472. |
we demonstrated previously that reactive microglia foster k(atp) -channel expression and that blocking this channel using glibenclamide administration enhances striatal neurogenesis after stroke. |
2014-09-26 |
2023-08-12 |
mouse |
| Miriana Jlenia Quattromani, Pierre Cordeau, Karsten Ruscher, Jasna Kriz, Tadeusz Wieloc. Enriched housing down-regulates the Toll-like receptor 2 response in the mouse brain after experimental stroke. Neurobiology of disease. vol 66. 2014-09-24. PMID:24613658. |
in order to identify targets for late stroke treatment, we studied the dynamics of inflammation and the contribution of resident toll-like receptor 2 (tlr2) expressing microglia cells. |
2014-09-24 |
2023-08-12 |
mouse |
| Miriana Jlenia Quattromani, Pierre Cordeau, Karsten Ruscher, Jasna Kriz, Tadeusz Wieloc. Enriched housing down-regulates the Toll-like receptor 2 response in the mouse brain after experimental stroke. Neurobiology of disease. vol 66. 2014-09-24. PMID:24613658. |
tlr2-expressing microglia cells may provide targets for new stroke therapeutics. |
2014-09-24 |
2023-08-12 |
mouse |
| Ukpong B Eyo, Sam A Miner, Katelin E Ahlers, Long-Jun Wu, Michael E Daile. P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation. Neuropharmacology. vol 73. 2014-08-13. PMID:23770338. |
brain-resident microglia may promote tissue repair following stroke but, like other cells, they are vulnerable to ischemia. |
2014-08-13 |
2023-08-12 |
mouse |
| Paolo Gelosa, Davide Lecca, Marta Fumagalli, Dorota Wypych, Alice Pignieri, Mauro Cimino, Claudia Verderio, Malin Enerbäck, Elham Nikookhesal, Elena Tremoli, Maria P Abbracchio, Luigi Siron. Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 6. 2014-07-21. PMID:24643079. |
microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor. |
2014-07-21 |
2023-08-12 |
mouse |
| Sébastien Lenglet, Fabrizio Montecucco, Adam Denes, Graham Coutts, Emmanuel Pinteaux, François Mach, Karl Schaller, Yvan Gasche, Jean-Christophe Copi. Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 5. 2014-06-17. PMID:24473480. |
recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. |
2014-06-17 |
2023-08-12 |
mouse |
| Sébastien Lenglet, Fabrizio Montecucco, Adam Denes, Graham Coutts, Emmanuel Pinteaux, François Mach, Karl Schaller, Yvan Gasche, Jean-Christophe Copi. Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 5. 2014-06-17. PMID:24473480. |
in conclusion, we report for the first time that rtpa amplified microglia recruitment early after stroke in association with a rapid ccl3 production. |
2014-06-17 |
2023-08-12 |
mouse |
| Ye Jin, Koichi Sato, Ayaka Tobo, Chihiro Mogi, Masayuki Tobo, Naoya Murata, Satoshi Ishii, Dong-Soon Im, Fumikazu Okajim. Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia. Journal of neurochemistry. vol 129. issue 4. 2014-06-15. PMID:24447140. |
interleukin-1β (il-1β) is released from activated microglia and involved in the neurodegeneration of acute and chronic brain disorders, such as stroke and alzheimer's disease, in which extracellular acidification has been shown to occur. |
2014-06-15 |
2023-08-12 |
mouse |
| Haixia Hu, Zuanfang Li, Xiaoqin Zhu, Ruhui Lin, Lidian Che. Salidroside Reduces Cell Mobility via NF- κ B and MAPK Signaling in LPS-Induced BV2 Microglial Cells. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-27. PMID:24864151. |
the unregulated activation of microglia following stroke results in the production of toxic factors that propagate secondary neuronal injury. |
2014-05-27 |
2023-08-13 |
Not clear |
| Robert Bronstein, Luisa Torres, Jillian C Nissen, Stella E Tsirk. Culturing microglia from the neonatal and adult central nervous system. Journal of visualized experiments : JoVE. issue 78. 2014-03-11. PMID:23962915. |
microglia can be activated and recruited to action by neuronal injury or stimulation, such as axonal damage seen in ms or ischemic brain trauma resulting from stroke. |
2014-03-11 |
2023-08-12 |
Not clear |
| Stephen D Skaper, Laura Facci, Pietro Giust. Intracellular ion channel CLIC1: involvement in microglia-mediated β-amyloid peptide(1-42) neurotoxicity. Neurochemical research. vol 38. issue 9. 2014-03-10. PMID:23743620. |
microglia can exacerbate central nervous system disorders, including stroke and chronic progressive neurodegenerative diseases such as alzheimer disease. |
2014-03-10 |
2023-08-12 |
Not clear |
| Han-Ning Chuang, Denise van Rossum, Dirk Sieger, Laila Siam, Florian Klemm, Annalen Bleckmann, Michaela Bayerlová, Katja Farhat, Jörg Scheffel, Matthias Schulz, Faramarz Dehghani, Christine Stadelmann, Uwe-Karsten Hanisch, Claudia Binder, Tobias Pukro. Carcinoma cells misuse the host tissue damage response to invade the brain. Glia. vol 61. issue 8. 2014-03-10. PMID:23832647. |
furthermore, cxcr4-regulated microglia were recruited to sites of brain injury in a zebrafish model and cxcr4 was expressed in human stroke patients, suggesting a conserved role in damage responses to various types of brain injuries. |
2014-03-10 |
2023-08-12 |
human |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
stroke induces rapid activation and expansion of microglia, but the main source of microgliosis is controversial. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
in contrast, reactive microglia were recruited to the ischaemic area continuously during the first week after stroke induction. |
2014-02-10 |
2023-08-12 |
Not clear |
| Ting Li, Shengru Pang, Yongping Yu, Xiaoqian Wu, Jing Guo, Shengxiang Zhan. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24154617. |
together, these results indicated that cx3cr1(gfp/+) infiltrating cells and reactive microglia represented two distinct populations of cells with different functions and therapeutic potentials for the treatment of stroke. |
2014-02-10 |
2023-08-12 |
Not clear |