| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Wang, Tianzi Jiang, Zhiguo Sun, Siew-Leng Teng, Xingguang Luo, Zhongjun Zhu, Yufeng Zang, Handi Zhang, Weihua Yue, Mei Qu, Tianlan Lu, Nan Hong, Haiyan Huang, Hilary P Blumberg, Dai Zhan. Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls. Journal of psychiatry & neuroscience : JPN. vol 34. issue 3. 2009-07-30. PMID:19448847. |
the present study investigated the potential contribution of nrg1 variation to anterior cingulum abnormalities in participants with schizophrenia. |
2009-07-30 |
2023-08-12 |
human |
| Daphne Voineskos, Vincenzo De Luca, Stuart Macgregor, Olga Likhodi, Laura Miller, Aristotle N Voineskos, James L Kenned. Neuregulin 1 and age of onset in the major psychoses. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 4. 2009-06-09. PMID:19184335. |
neuregulin 1 (nrg1) is a large gene on chromosome 8p, that has been identified as a susceptibility factor in bipolar disorder and schizophrenia. |
2009-06-09 |
2023-08-12 |
Not clear |
| Hong-xing Zhang, Wen-qiang Li, Yan Zhang, Jing-ping Zhao, Lu-xian Lv, Ge Yan. [Association analysis of neuregulin 1 gene polymorphism with schizophrenia in Chinese Han population]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 26. issue 1. 2009-05-20. PMID:19199244. |
to investigate the association of the neuregulin 1(nrg1) gene polymorphism with schizophrenia by analyzing allele transmission in schizophrenic parent-proband trios. |
2009-05-20 |
2023-08-12 |
Not clear |
| Ignacio Mata, Rocio Perez-Iglesias, Roberto Roiz-Santiañez, Diana Tordesillas-Gutierrez, Andres Gonzalez-Mandly, Jose Luis Vazquez-Barquero, Benedicto Crespo-Facorr. A neuregulin 1 variant is associated with increased lateral ventricle volume in patients with first-episode schizophrenia. Biological psychiatry. vol 65. issue 6. 2009-05-19. PMID:19058791. |
a single nucleotide polymorphism (snp) within nrg1, snp8nrg243177, has been associated with brain function among healthy and high-risk subjects and with reduced cell migration among patients with schizophrenia. |
2009-05-19 |
2023-08-12 |
human |
| Tilo Kircher, Renate Thienel, Michael Wagner, Martina Reske, Ute Habel, Thilo Kellermann, Ingo Frommann, Sibylle Schwab, Wolfgang Wölwer, Martina von Wilmsdorf, Dieter F Braus, Andrea Schmitt, Alexander Rapp, Tony Stöcker, N Jon Shah, Fritz A Henn, Heinrich Sauer, Wolfgang Gaebel, Wolfgang Maier, Frank Schneide. Neuregulin 1 ICE-single nucleotide polymorphism in first episode schizophrenia correlates with cerebral activation in fronto-temporal areas. European archives of psychiatry and clinical neuroscience. vol 259. issue 2. 2009-05-13. PMID:18806920. |
brain regions previously associated with the pathology of schizophrenia are differentially affected in those with a genetic at risk status in the nrg1 gene. |
2009-05-13 |
2023-08-12 |
Not clear |
| Andrea Schmitt, Eleni Parlapani, Oliver Gruber, Thomas Wobrock, Peter Falka. Impact of neuregulin-1 on the pathophysiology of schizophrenia in human post-mortem studies. European archives of psychiatry and clinical neuroscience. vol 258 Suppl 5. 2009-04-09. PMID:18985292. |
to a large extend schizophrenia has been shown to be heritable, with neuregulin-1 (nrg1) one of the candidate genes considered to play a role in the pathophysiology of the disorder. |
2009-04-09 |
2023-08-12 |
human |
| Andrea Schmitt, Eleni Parlapani, Oliver Gruber, Thomas Wobrock, Peter Falka. Impact of neuregulin-1 on the pathophysiology of schizophrenia in human post-mortem studies. European archives of psychiatry and clinical neuroscience. vol 258 Suppl 5. 2009-04-09. PMID:18985292. |
nrg1 isoforms are differentially expressed in relevant brain regions of schizophrenia patients such as the prefrontal cortex and hippocampus and may contribute to pathophysiological processes. |
2009-04-09 |
2023-08-12 |
human |
| Andreas Konrad, Goran Vucurevic, Francesco Musso, Peter Stoeter, Norbert Dahmen, Georg Wintere. ErbB4 genotype predicts left frontotemporal structural connectivity in human brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 3. 2009-03-30. PMID:18668031. |
several investigations have suggested that variations of the genes that encode the neuregulin 1 (nrg1)-erbb4 receptor complex are associated with schizophrenia illness. |
2009-03-30 |
2023-08-12 |
human |
| Carmen Birchmeie. ErbB receptors and the development of the nervous system. Experimental cell research. vol 315. issue 4. 2009-03-23. PMID:19046966. |
neuregulin signals are also important in other organs, but the nervous system functions have received recently considerable attention due to the finding that particular haplotypes of nrg1 and erbb4 predispose to schizophrenia. |
2009-03-23 |
2023-08-12 |
Not clear |
| Jonathan D Wood, Franziska Bonath, Shashvita Kumar, Christopher A Ross, Vincent T Cunliff. Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain. Human molecular genetics. vol 18. issue 3. 2009-02-27. PMID:18996920. |
schizophrenia may arise from subtle abnormalities in brain development due to alterations in the functions of candidate susceptibility genes such as disrupted-in-schizophrenia 1 (disc1) and neuregulin 1 (nrg1). |
2009-02-27 |
2023-08-12 |
mouse |
| Jonathan D Wood, Franziska Bonath, Shashvita Kumar, Christopher A Ross, Vincent T Cunliff. Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain. Human molecular genetics. vol 18. issue 3. 2009-02-27. PMID:18996920. |
like disc1 and nrg1, olig2 and erbb4 are promising candidate susceptibility genes for schizophrenia. |
2009-02-27 |
2023-08-12 |
mouse |
| Jonathan D Wood, Franziska Bonath, Shashvita Kumar, Christopher A Ross, Vincent T Cunliff. Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain. Human molecular genetics. vol 18. issue 3. 2009-02-27. PMID:18996920. |
these connections could be investigated in disc1 and nrg1 mouse models and in genetically defined groups of patients in order to determine whether they are relevant to the pathobiology of schizophrenia. |
2009-02-27 |
2023-08-12 |
mouse |
| Lieve Desbonnet, John L Waddington, Colm M P O'Tuathaig. Mutant models for genes associated with schizophrenia. Biochemical Society transactions. vol 37. issue Pt 1. 2009-02-11. PMID:19143653. |
thereafter, we consider recent findings, with a particular focus on, first, dopaminergic and glutamatergic pathophysiological models and, secondly, putative roles for disc1 (disrupted in schizophrenia 1) and nrg1 (neuregulin 1) as susceptibility genes for schizophrenia. |
2009-02-11 |
2023-08-12 |
mouse |
| Daria Krivosheya, Lucia Tapia, Joshua N Levinson, Kun Huang, Yunhee Kang, Rochelle Hines, Annie K Ting, Ann Marie Craig, Lin Mei, Shernaz X Bamji, Alaa El-Hussein. ErbB4-neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms. The Journal of biological chemistry. vol 283. issue 47. 2009-01-22. PMID:18819924. |
perturbations in neuregulin-1 (nrg1)/erbb4 function have been associated with schizophrenia. |
2009-01-22 |
2023-08-12 |
Not clear |
| Oliver Gruber, Peter Falkai, Thomas Schneider-Axmann, Sibylle G Schwab, Michael Wagner, Wolfgang Maie. Neuregulin-1 haplotype HAP(ICE) is associated with lower hippocampal volumes in schizophrenic patients and in non-affected family members. Journal of psychiatric research. vol 43. issue 1. 2009-01-12. PMID:18291420. |
the neuregulin-1 (nrg1) gene on chromosome 8p has been suggested as a potential susceptibility gene for schizophrenia. |
2009-01-12 |
2023-08-12 |
human |
| K K Nicodemus, S Marenco, A J Batten, R Vakkalanka, M F Egan, R E Straub, D R Weinberge. Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk. Molecular psychiatry. vol 13. issue 9. 2009-01-07. PMID:18195713. |
we sought to test whether a set of schizophrenia candidate genes regulated by hypoxia or involved in vascular function in the brain (akt1, bdnf, capon, chrna7, comt, dtnbp1, gad1, grm3, notch4, nrg1, prodh, rgs4, tnf-alpha) interacted with serious obstetric complications to influence risk for schizophrenia. |
2009-01-07 |
2023-08-12 |
Not clear |
| Axel Krug, Valentin Markov, Thomas Eggermann, Sören Krach, Klaus Zerres, Tony Stöcker, N Jon Shah, Frank Schneider, Markus M Nöthen, Jens Treutlein, Marcella Rietschel, Tilo Kirche. Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with differences in frontal brain activation in a working memory task in healthy individuals. NeuroImage. vol 42. issue 4. 2008-12-29. PMID:18606232. |
the aim of the present study was to test the influence of the nrg1 schizophrenia susceptibility gene on working memory and its neural correlates in healthy subjects. |
2008-12-29 |
2023-08-12 |
human |
| Carlo Colantuoni, Thomas M Hyde, Shruti Mitkus, Andrew Joseph, Leah Sartorius, Claudia Aguirre, Johanna Creswell, Elizabeth Johnson, Amy Deep-Soboslay, Mary M Herman, Barbara K Lipska, Daniel R Weinberger, Joel E Kleinma. Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex. Brain structure & function. vol 213. issue 1-2. 2008-12-02. PMID:18470533. |
nrg1, erbb3, and ngfr show expression changes during the years of greatest risk for the development of schizophrenia. |
2008-12-02 |
2023-08-12 |
human |
| Sae Shiota, Mamoru Tochigi, Hiroko Shimada, Jun Ohashi, Kiyoto Kasai, Nobumasa Kato, Katsushi Tokunaga, Tsukasa Sasak. Association and interaction analyses of NRG1 and ERBB4 genes with schizophrenia in a Japanese population. Journal of human genetics. vol 53. issue 10. 2008-11-18. PMID:18704261. |
association and interaction analyses of nrg1 and erbb4 genes with schizophrenia in a japanese population. |
2008-11-18 |
2023-08-12 |
Not clear |
| Sae Shiota, Mamoru Tochigi, Hiroko Shimada, Jun Ohashi, Kiyoto Kasai, Nobumasa Kato, Katsushi Tokunaga, Tsukasa Sasak. Association and interaction analyses of NRG1 and ERBB4 genes with schizophrenia in a Japanese population. Journal of human genetics. vol 53. issue 10. 2008-11-18. PMID:18704261. |
neuregulin 1 (nrg1) is one of the most promising candidate genes for schizophrenia. |
2008-11-18 |
2023-08-12 |
Not clear |