| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Daniela Vidinsk\\xc3\\xa1, Petra Vochozkov\\xc3\\xa1, Petra \\xc5\\xa0matl\\xc3\\xadkov\\xc3\\xa1, Taras Ardan, Ji\\xc5\\x99\\xc3\\xad Kl\\xc3\\xadma, \\xc5\\xa0tefan Juh\\xc3\\xa1s, Jana Juh\\xc3\\xa1sov\\xc3\\xa1, Bo\\xc5\\xbeena Bohuslavov\\xc3\\xa1, Monika Baxa, Ivona Valekov\\xc3\\xa1, Jan Motl\\xc3\\xadk, Zdenka Ellederov\\xc3\\xa. Gradual Phenotype Development in Huntington Disease Transgenic Minipig Model at 24 Months of Age. Neuro-degenerative diseases. vol 18. issue 2-3. 2019-01-30. PMID:29870995.' |
huntington disease (hd) is an incurable neurodegenerative disease caused by the expansion of a polyglutamine sequence in a gene encoding the huntingtin (htt) protein, which is expressed in almost all cells of the body. |
2019-01-30 |
2023-08-13 |
Not clear |
| Wan Song, Nóra Zsindely, Anikó Faragó, J Lawrence Marsh, László Boda. Systematic genetic interaction studies identify histone demethylase Utx as potential target for ameliorating Huntington's disease. Human molecular genetics. vol 27. issue 4. 2019-01-07. PMID:29281014. |
huntington's disease (hd) is a dominantly inherited neurodegenerative disease caused by alterations in the huntingtin gene (htt). |
2019-01-07 |
2023-08-13 |
drosophila_melanogaster |
| Ching-Chi Chang, Tzu-Chin Lin, Hsiao-Li Ho, Chien-Yin Kuo, Hsin-Hua Li, Tatiana A Korolenko, Wei-Jen Chen, Te-Jen Lai, Ying-Jui Ho, Chih-Li Li. GLP-1 Analogue Liraglutide Attenuates Mutant Huntingtin-Induced Neurotoxicity by Restoration of Neuronal Insulin Signaling. International journal of molecular sciences. vol 19. issue 9. 2018-12-11. PMID:30149534. |
huntington's disease (hd) is a progressive and fatal neurodegenerative disease caused by cag repeat expansion in the coding region of huntingtin (htt) protein. |
2018-12-11 |
2023-08-13 |
Not clear |
| Rocio Gomez-Pastor, Eileen T Burchfiel, Daniel W Neef, Alex M Jaeger, Elisa Cabiscol, Spencer U McKinstry, Argenia Doss, Alejandro Aballay, Donald C Lo, Sergey S Akimov, Christopher A Ross, Cagla Eroglu, Dennis J Thiel. Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nature communications. vol 8. 2018-11-26. PMID:28194040. |
huntington's disease (hd) is a neurodegenerative disease caused by poly-glutamine expansion in the htt protein, resulting in htt misfolding and cell death. |
2018-11-26 |
2023-08-13 |
mouse |
| Chaohua Peng, Gaochun Zhu, Xiangqian Liu, He L. Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. Neuroscience bulletin. vol 34. issue 5. 2018-11-06. PMID:29713895. |
huntington's disease (hd) is a neurodegenerative disease caused by a polyglutamine expansion in the huntingtin (htt) protein. |
2018-11-06 |
2023-08-13 |
mouse |
| Xiaoyu Dong, Shuyan Con. Bioinformatic analysis of microRNA expression in Huntington's disease. Molecular medicine reports. vol 18. issue 3. 2018-10-26. PMID:30015953. |
huntington's disease (hd) is an inherited, progressive neurodegenerative disease caused by a cag expansion in the huntingtin (htt) gene and various dysfunctions of biological processes in hd have been proposed. |
2018-10-26 |
2023-08-13 |
Not clear |
| Andreas Reif, Anass Chiki, Jonathan Ricci, Hilal A Lashue. Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy. Journal of visualized experiments : JoVE. issue 136. 2018-09-10. PMID:30010666. |
huntington's disease (hd) is an inherited fatal neurodegenerative disease caused by a cag expansion (≥36) in the first exon of the hd gene, resulting in the expression of the huntingtin protein (htt) or n-terminal fragments thereof with an expanded polyglutamine (polyq) stretch. |
2018-09-10 |
2023-08-13 |
Not clear |
| Kuo-Hsuan Chang, Yih-Ru Wu, Chiung-Mei Che. Down-regulation of miR-9* in the peripheral leukocytes of Huntington's disease patients. Orphanet journal of rare diseases. vol 12. issue 1. 2018-09-04. PMID:29258536. |
huntington's disease (hd), caused by expansion of a polyglutamine tract within huntingtin (htt) protein, is an autosomal dominant neurodegenerative disease associated with a progressive neurodegeneration of striatum and cerebral cortex. |
2018-09-04 |
2023-08-13 |
Not clear |
| Xiaoyu Dong, Shuyan Con. Identification of differentially expressed genes and regulatory relationships in Huntington's disease by bioinformatics analysis. Molecular medicine reports. vol 17. issue 3. 2018-08-16. PMID:29328442. |
huntington's disease (hd) is an inherited, progressive neurodegenerative disease caused by a cag expansion in the huntingtin (htt) gene; various dysfunctions of biological processes in hd have been proposed. |
2018-08-16 |
2023-08-13 |
Not clear |
| Khaled S Abd-Elrahman, Alison Hamilton, Shaunessy R Hutchinson, Fang Liu, Ryan C Russell, Stephen S G Ferguso. mGluR5 antagonism increases autophagy and prevents disease progression in the Science signaling. vol 10. issue 510. 2018-08-02. PMID:29259100. |
mglur5 antagonism increases autophagy and prevents disease progression in the huntington's disease (hd) is a neurodegenerative disease caused by an expansion in the huntingtin protein (also called htt) that induces neuronal cell death with age. |
2018-08-02 |
2023-08-13 |
Not clear |
| Dmitry Perminov, Ludmila Voložonoka, Liene Korņejeva, Evija Jokste-Pțmane, Arita Blumberga, Sandra Krasucka, Nellija Seimuškina, Irina Kovaļova, Violeta Fodin. First preimplantation genetic testing case for monogenic disease in Latvia. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 33. issue sup1. 2018-07-31. PMID:29264979. |
huntington's disease (hd) is fatal neurodegenerative disease caused by a (cag) triplet repeat expansion in the huntingtin (htt) gene. |
2018-07-31 |
2023-08-13 |
Not clear |
| Caitlin S Latimer, Margaret E Flanagan, Patrick J Cimino, Suman Jayadev, Marie Davis, Zachary S Hoffer, Thomas J Montine, Luis F Gonzalez-Cuyar, Thomas D Bird, C Dirk Keen. Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son. Journal of Huntington's disease. vol 6. issue 4. 2018-07-30. PMID:29036832. |
huntington's disease (hd) is an autosomal dominant neurodegenerative disease caused by a trinucleotide (cag) repeat expansion in huntingtin (htt) on chromosome 4. |
2018-07-30 |
2023-08-13 |
Not clear |
| Mingchen Chen, Peter G Wolyne. Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 17. 2018-05-15. PMID:28400517. |
huntington's disease (hd) is a neurodegenerative disease caused by an abnormal expansion in the polyglutamine (polyq) track of the huntingtin (htt) protein. |
2018-05-15 |
2023-08-13 |
mouse |
| Leili Zhang, Hongsuk Kang, Francisco X Vázquez, Leticia Toledo-Sherman, Binquan Luan, Ruhong Zho. Molecular Mechanism of Stabilizing the Helical Structure of Huntingtin N17 in a Micellar Environment. The journal of physical chemistry. B. vol 121. issue 18. 2018-05-08. PMID:28413881. |
huntington's disease is a deadly neurodegenerative disease caused by the fibrilization of huntingtin (htt) exon-1 protein mutants. |
2018-05-08 |
2023-08-13 |
Not clear |
| Kyung-Ah Choi, Sunghoi Hon. Induced neural stem cells as a means of treatment in Huntington's disease. Expert opinion on biological therapy. vol 17. issue 11. 2018-02-06. PMID:28792249. |
huntington's disease (hd) is an inherited neurodegenerative disease characterized by chorea, dementia, and depression caused by progressive nerve cell degeneration, which is triggered by expanded cag repeats in the huntingtin (htt) gene. |
2018-02-06 |
2023-08-13 |
Not clear |
| Michael J Chao, Tammy Gillis, Ranjit S Atwal, Jayalakshmi Srinidhi Mysore, Jamshid Arjomand, Denise Harold, Peter Holmans, Lesley Jones, Michael Orth, Richard H Myers, Seung Kwak, Vanessa C Wheeler, Marcy E MacDonald, James F Gusella, Jong-Min Le. Haplotype-based stratification of Huntington's disease. European journal of human genetics : EJHG. vol 25. issue 11. 2018-02-01. PMID:28832564. |
huntington's disease (hd) is an autosomal dominant neurodegenerative disease caused by expansion of a cag trinucleotide repeat in htt, resulting in an extended polyglutamine tract in huntingtin. |
2018-02-01 |
2023-08-13 |
human |
| Jong-Min Lee, Michael J Chao, Denise Harold, Kawther Abu Elneel, Tammy Gillis, Peter Holmans, Lesley Jones, Michael Orth, Richard H Myers, Seung Kwak, Vanessa C Wheeler, Marcy E MacDonald, James F Gusell. A modifier of Huntington's disease onset at the MLH1 locus. Human molecular genetics. vol 26. issue 19. 2018-01-23. PMID:28934397. |
huntington's disease (hd) is a dominantly inherited neurodegenerative disease caused by an expanded cag repeat in htt. |
2018-01-23 |
2023-08-13 |
mouse |
| Ian H Kratter, Hengameh Zahed, Alice Lau, Andrey S Tsvetkov, Aaron C Daub, Kurt F Weiberth, Xiaofeng Gu, Frédéric Saudou, Sandrine Humbert, X William Yang, Alex Osmand, Joan S Steffan, Eliezer Masliah, Steven Finkbeine. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of clinical investigation. vol 126. issue 9. 2017-09-26. PMID:27525439. |
huntington's disease (hd) is a progressive, adult-onset neurodegenerative disease caused by a polyglutamine (polyq) expansion in the n-terminal region of the protein huntingtin (htt). |
2017-09-26 |
2023-08-13 |
mouse |
| Yu-Han Kao, Yijuang Chern, Hui-Ting Yang, Hui-Mei Chen, Chun-Jung Li. Regulation of P-glycoprotein expression in brain capillaries in Huntington's disease and its impact on brain availability of antipsychotic agents risperidone and paliperidone. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 36. issue 8. 2017-07-19. PMID:26661162. |
huntington's disease (hd) is a neurodegenerative disease marked by an expanded polyglutamine (polyq) tract on the huntingtin (htt) protein that may cause transcriptional dysfunction. |
2017-07-19 |
2023-08-13 |
mouse |
| Tanja Hering, Peter Braubach, G Bernhard Landwehrmeyer, Katrin S Lindenberg, Werner Melze. Fast-to-Slow Transition of Skeletal Muscle Contractile Function and Corresponding Changes in Myosin Heavy and Light Chain Formation in the R6/2 Mouse Model of Huntington's Disease. PloS one. vol 11. issue 11. 2017-06-27. PMID:27820862. |
huntington´s disease (hd) is a hereditary neurodegenerative disease resulting from an expanded polyglutamine sequence (poly-q) in the protein huntingtin (htt). |
2017-06-27 |
2023-08-13 |
mouse |