| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Magdalena Czeredys, Filip Maciag, Axel Methner, Jacek Kuznick. Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease. Biochemical and biophysical research communications. vol 483. issue 4. 2017-06-06. PMID:27553284. |
huntington's disease (hd) is a hereditary neurodegenerative disease caused by a polyglutamine expansion within the huntingtin (htt) gene. |
2017-06-06 |
2023-08-13 |
mouse |
| Amber L Southwell, Niels H Skotte, Erika B Villanueva, Michael E Østergaard, Xiaofeng Gu, Holly B Kordasiewicz, Chris Kay, Daphne Cheung, Yuanyun Xie, Sabine Waltl, Louisa Dal Cengio, Hailey Findlay-Black, Crystal N Doty, Eugenia Petoukhov, Diepiriye Iworima, Ramy Slama, Jolene Ooi, Mahmoud A Pouladi, X William Yang, Eric E Swayze, Punit P Seth, Michael R Hayde. A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles. Human molecular genetics. vol 26. issue 6. 2017-05-15. PMID:28104789. |
huntington disease (hd) is a neurodegenerative disease caused by a mutation in the huntingtin (htt) gene. |
2017-05-15 |
2023-08-13 |
mouse |
| Seth A Ament, Jocelynn R Pearl, Andrea Grindeland, Jason St Claire, John C Earls, Marina Kovalenko, Tammy Gillis, Jayalakshmi Mysore, James F Gusella, Jong-Min Lee, Seung Kwak, David Howland, Min Young Lee, David Baxter, Kelsey Scherler, Kai Wang, Donald Geman, Jeffrey B Carroll, Marcy E MacDonald, George Carlson, Vanessa C Wheeler, Nathan D Price, Leroy E Hoo. High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds. Human molecular genetics. vol 26. issue 5. 2017-05-15. PMID:28334820. |
huntington's disease is a dominantly inherited neurodegenerative disease caused by the expansion of a cag repeat in the htt gene. |
2017-05-15 |
2023-08-13 |
mouse |
| Fang Fang, Ting Peng, Shiming Yang, Weixi Wang, Yinong Zhang, He L. Lycium barbarum polysaccharide attenuates the cytotoxicity of mutant huntingtin and increases the activity of AKT. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 52. 2017-03-27. PMID:27196502. |
huntington's disease (hd) is an inherited neurodegenerative disease that is caused by the abnormal expansion of cag repeats in the gene encoding huntingtin (htt). |
2017-03-27 |
2023-08-13 |
mouse |
| Jing Yang, Ke Chen, Qianqian Wei, Yongping Chen, Bei Cao, Jean-Marc Burgunder, Hui-Fang Shan. Clinical and genetic characteristics in patients with Huntington's disease from China. Neurological research. vol 38. issue 10. 2017-01-17. PMID:27483361. |
huntington's disease (hd) is a neurodegenerative disease caused by the expansion of unstable cag repeats in the htt gene. |
2017-01-17 |
2023-08-13 |
Not clear |
| Mayke Oosterloo, Martine J Van Belzen, Emilia K Bijlsma, Raymund A C Roo. Is There Convincing Evidence that Intermediate Repeats in the HTT Gene Cause Huntington's Disease? Journal of Huntington's disease. vol 4. issue 2. 2016-06-15. PMID:26397895. |
huntington's disease (hd) is a neurodegenerative disease associated with a cag repeat expansion in the huntingtin (htt) gene. |
2016-06-15 |
2023-08-13 |
Not clear |
| Xiang Gao, Warren A Campbell, Maxmore Chaibva, Pranav Jain, Ashley E Leslie, Shelli L Frey, Justin Legleite. Cholesterol Modifies Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes. Biochemistry. vol 55. issue 1. 2016-05-13. PMID:26652744. |
huntington's disease (hd) is an inherited neurodegenerative disease caused by abnormally long cag-repeats in the huntingtin gene that encode an expanded polyglutamine (polyq) domain near the n-terminus of the huntingtin (htt) protein. |
2016-05-13 |
2023-08-13 |
Not clear |
| Sudha Bucha, Debashis Mukhopadhyay, Nitai Pada Bhattacharyy. Regulation of mitochondrial morphology and cell cycle by microRNA-214 targeting Mitofusin2. Biochemical and biophysical research communications. vol 465. issue 4. 2016-04-12. PMID:26307536. |
huntington's disease (hd) is an autosomal dominant neurodegenerative disease caused by the increase in cag repeats beyond 36 at the exon1 of the gene huntingtin (htt). |
2016-04-12 |
2023-08-13 |
Not clear |
| Kazem Mousavizadeh, Peyman Rajabi, Mahsa Alaee, Sepideh Dadgar, Massoud Houshman. Usage of mitochondrial D-loop variation to predict risk for Huntington disease. Mitochondrial DNA. vol 26. issue 4. 2016-03-24. PMID:24471944. |
huntington's disease (hd) is an inherited autosomal neurodegenerative disease caused by the abnormal expansion of the cag repeats in the huntingtin (htt) gene. |
2016-03-24 |
2023-08-12 |
Not clear |
| Shaun S Sanders, Michael R Hayde. Aberrant palmitoylation in Huntington disease. Biochemical Society transactions. vol 43. issue 2. 2016-01-01. PMID:25849918. |
huntington disease (hd) is an adult-onset neurodegenerative disease caused by a cag expansion in the htt gene. |
2016-01-01 |
2023-08-13 |
mouse |
| Bibiana K Y Wong, Dagmar E Ehrnhoefer, Rona K Graham, Dale D O Martin, Safia Ladha, Valeria Uribe, Lisa M Stanek, Sonia Franciosi, Xiaofan Qiu, Yu Deng, Vlad Kovalik, Weining Zhang, Mahmoud A Pouladi, Lamya S Shihabuddin, Michael R Hayde. Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice. Neurobiology of disease. vol 76. 2015-12-14. PMID:25583186. |
huntington disease (hd) is a progressive neurodegenerative disease caused by an elongated cag repeat in the huntingtin (htt) gene that encodes a polyglutamine tract in the htt protein. |
2015-12-14 |
2023-08-13 |
mouse |
| Ilenia Ventura, Maria Teresa Russo, Chiara De Nuccio, Gabriele De Luca, Paolo Degan, Antonietta Bernardo, Sergio Visentin, Luisa Minghetti, Margherita Bignam. hMTH1 expression protects mitochondria from Huntington's disease-like impairment. Neurobiology of disease. vol 49. 2015-11-10. PMID:22974734. |
huntington disease (hd) is a neurodegenerative disease caused by expansion of cag repeats in the huntingtin (htt) gene. |
2015-11-10 |
2023-08-12 |
mouse |
| Ladislav Mrzljak, Ignacio Munoz-Sanjua. Therapeutic Strategies for Huntington's Disease. Current topics in behavioral neurosciences. vol 22. 2015-09-10. PMID:24277342. |
huntington's disease (hd) is a devastating autosomal dominant neurodegenerative disease, caused by expansion of the cag repeat in the huntingtin (htt) gene and characterized pathologically by the loss of pyramidal neurons in several cortical areas, of striatal medium spiny neurons, and of hypothalamic neurons. |
2015-09-10 |
2023-08-12 |
Not clear |
| Shaun S Sanders, Katherine K N Mui, Liza M Sutton, Michael R Hayde. Identification of binding sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L. PloS one. vol 9. issue 2. 2015-06-26. PMID:24651384. |
huntington disease is an adult onset neurodegenerative disease characterized by motor, cognitive, and psychiatric dysfunction, caused by a cag expansion in the htt gene. |
2015-06-26 |
2023-08-12 |
Not clear |
| Nicolas Merienne, Nicole Déglo. [Gene silencing approaches for the treatment of Huntington's disease]. Medecine sciences : M/S. vol 31. issue 2. 2015-04-30. PMID:25744262. |
huntington's disease is a rare neurodegenerative disease caused by a pathologic cag expansion in the exon 1 of the huntingtin (htt) gene. |
2015-04-30 |
2023-08-13 |
Not clear |
| Alex Mas Monteys, Matthew J Wilson, Ryan L Boudreau, Ryan M Spengler, Beverly L Davidso. Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo. Molecular therapy. Nucleic acids. vol 4. 2015-04-08. PMID:25849618. |
huntington's disease (hd) is a dominantly inherited neurodegenerative disease caused by cag repeat expansion in exon 1 of huntingtin (htt). |
2015-04-08 |
2023-08-13 |
mouse |
| Shaun S Sanders, Juan Hou, Liza M Sutton, Victoria C Garside, Katherine K N Mui, Roshni R Singaraja, Michael R Hayden, Pamela A Hoodles. Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development. Developmental biology. vol 397. issue 2. 2015-03-04. PMID:25478910. |
huntington disease (hd) is an adult-onset neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms that is caused by a cag expansion in the htt gene. |
2015-03-04 |
2023-08-13 |
mouse |
| Alex Mas Monteys, Ryan M Spengler, Brett D Dufour, Matt S Wilson, Clayton K Oakley, Matt J Sowada, Jodi L McBride, Beverly L Davidso. Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain. Nucleic acids research. vol 42. issue 21. 2015-01-27. PMID:25332397. |
huntington's disease is a fatal neurodegenerative disease caused by polyglutamine-expansion in huntingtin (htt). |
2015-01-27 |
2023-08-13 |
mouse |
| Lisa M Stanek, Sergio P Sardi, Bryan Mastis, Amy R Richards, Christopher M Treleaven, Tatyana Taksir, Kuma Misra, Seng H Cheng, Lamya S Shihabuddi. Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease. Human gene therapy. vol 25. issue 5. 2014-12-30. PMID:24484067. |
huntington's disease (hd) is a fatal autosomal dominant neurodegenerative disease caused by an increase in the number of polyglutamine residues in the huntingtin (htt) protein. |
2014-12-30 |
2023-08-12 |
mouse |
| Zaira Ortega, Jose J Luca. Ubiquitin-proteasome system involvement in Huntington's disease. Frontiers in molecular neuroscience. vol 7. 2014-10-17. PMID:25324717. |
huntington's disease (hd) is a genetic autosomal dominant neurodegenerative disease caused by the expansion of a cag repeat in the huntingtin (htt) gene. |
2014-10-17 |
2023-08-13 |
Not clear |