| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joyce A Benjamin. Direct effects of secretory products of immune cells on neurons and glia. Journal of the neurological sciences. vol 333. issue 1-2. 2014-11-06. PMID:23827826. |
to explore the hypothesis that b cells of patients with multiple sclerosis secrete soluble products damaging to oligodendroglia (ol), in collaboration with dr. bar-or at montreal neurologic institute, we compared secretory products of cultured b cells from relapsing remitting multiple sclerosis (rrms) patients and healthy controls. |
2014-11-06 |
2023-08-12 |
rat |
| Aparna Shetty, Sheena G Gupta, Michel Varrin-Doyer, Martin S Weber, Thomas Prod'homme, Nicolas Molnarfi, Niannian Ji, Patricia A Nelson, Juan C Patarroyo, Ulf Schulze-Topphoff, Stephen E Fogal, Thomas Forsthuber, Raymond A Sobel, Claude C A Bernard, Anthony J Slavin, Scott S Zamvi. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 2. 2014-10-23. PMID:25340074. |
studies evaluating t-cell recognition of myelin oligodendrocyte glycoprotein (mog) in multiple sclerosis (ms) and its model, experimental autoimmune encephalomyelitis (eae), have focused mostly on its 117 amino acid (aa) extracellular domain, especially peptide (p) 35-55. |
2014-10-23 |
2023-08-13 |
Not clear |
| Ana Martins da Silva, Maria Ernestina Santo. JCV epidemiology in MS (JEMS)--epidemiology of anti-JCV antibody prevalence in multiple sclerosis patients--Portuguese data. Journal of the neurological sciences. vol 337. issue 1-2. 2014-10-06. PMID:24369270. |
progressive multifocal leukoencephalopathy, caused by oligodendrocyte lytic infection by jcvirus, is a growing concern for patients undergoing immune modulatory therapies for treatment of autoimmune diseases, such as multiple sclerosis (ms). |
2014-10-06 |
2023-08-12 |
Not clear |
| J J García-Vallejo, J M Ilarregui, H Kalay, S Chamorro, N Koning, W W Unger, M Ambrosini, V Montserrat, R J Fernandes, S C M Bruijns, J R T van Weering, N J Paauw, T O'Toole, J van Horssen, P van der Valk, K Nazmi, J G M Bolscher, J Bajramovic, C D Dijkstra, B A 't Hart, Y van Kooy. CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG. The Journal of experimental medicine. vol 211. issue 7. 2014-09-04. PMID:24935259. |
myelin oligodendrocyte glycoprotein (mog), a constituent of central nervous system myelin, is an important autoantigen in the neuroinflammatory disease multiple sclerosis (ms). |
2014-09-04 |
2023-08-13 |
human |
| De-Hyung Lee, Ralf A Linke. The role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? Expert opinion on therapeutic targets. vol 16. issue 5. 2014-08-29. PMID:22494461. |
the role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? |
2014-08-29 |
2023-08-12 |
Not clear |
| Jong-Hwan Lee, Hyuk Seong Seo, Jong Am Song, Koo Chul Kwon, Eun Jung Lee, Ho Jin Kim, Eun Bong Lee, Young Joo Cha, Jeewon Le. Proteinticle engineering for accurate 3D diagnosis. ACS nano. vol 7. issue 12. 2014-08-26. PMID:24195532. |
the surface display of the extracellular domain of myelin oligodendrocyte glycoprotein (mog) with native conformation successfully discriminated between autoantibodies to native or denatured mog, leading to the reliable diagnosis of multiple sclerosis with enhanced accuracy. |
2014-08-26 |
2023-08-12 |
human |
| Yiqiao Li, Yanyan Zhang, Weiwei Han, Fengyin Hu, Yu'e Qian, Qiang Che. TRO19622 promotes myelin repair in a rat model of demyelination. The International journal of neuroscience. vol 123. issue 11. 2014-05-19. PMID:23668883. |
multiple sclerosis is a neurodegenerative autoimmune disease characterized by diffuse oligodendrocyte injury, axonal loss and multifocal demyelination of myelin sheaths in the central nervous system. |
2014-05-19 |
2023-08-12 |
rat |
| Travis Burns, Laird Miers, Jie Xu, Alan Man, Monica Moreno, David Pleasure, Peter Bannerma. Neuronopathy in the motor neocortex in a chronic model of multiple sclerosis. Journal of neuropathology and experimental neurology. vol 73. issue 4. 2014-05-12. PMID:24607968. |
we provide evidence of cortical neuronopathy in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis, an established model of chronic multiple sclerosis. |
2014-05-12 |
2023-08-12 |
Not clear |
| Simon Zhornitsky, Voon Wee Yong, Marcus W Koch, Aaron Mackie, Stéphane Potvin, Scott B Patten, Luanne M Met. Quetiapine fumarate for the treatment of multiple sclerosis: focus on myelin repair. CNS neuroscience & therapeutics. vol 19. issue 10. 2014-05-08. PMID:23870612. |
multiple sclerosis (ms) is a central nervous system disorder that is associated with progressive oligodendrocyte and neuronal loss, axonal degeneration, and demyelination. |
2014-05-08 |
2023-08-12 |
Not clear |
| Cecile Delarasse, Paul Smith, David Baker, Sandra Amo. Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice. Immunology. vol 140. issue 4. 2014-04-18. PMID:23876060. |
myelin oligodendrocyte glycoprotein (mog), a minor protein of the central nervous system myelin, is recognized as a potential target in multiple sclerosis and neuromyelitis optica. |
2014-04-18 |
2023-08-12 |
mouse |
| Walaa F Alsanie, Jonathan C Niclis, Steven Petrato. Human embryonic stem cell-derived oligodendrocytes: protocols and perspectives. Stem cells and development. vol 22. issue 18. 2014-04-07. PMID:23621561. |
disruption of fast axonal transport mechanisms can occur as a consequence of mature oligodendrocyte loss following spinal cord injury, stroke, or due to neuroinflammatory conditions, such as multiple sclerosis. |
2014-04-07 |
2023-08-12 |
human |
| Jenea M Bin, Sathyanath Rajasekharan, Tanja Kuhlmann, Ilana Hanes, Nathalie Marcal, Dong Han, Sonia P Rodrigues, Soo Yuen Leong, Jia Newcombe, Jack P Antel, Timothy E Kenned. Full-length and fragmented netrin-1 in multiple sclerosis plaques are inhibitors of oligodendrocyte precursor cell migration. The American journal of pathology. vol 183. issue 3. 2014-03-12. PMID:23831296. |
full-length and fragmented netrin-1 in multiple sclerosis plaques are inhibitors of oligodendrocyte precursor cell migration. |
2014-03-12 |
2023-08-12 |
human |
| Jenea M Bin, Sathyanath Rajasekharan, Tanja Kuhlmann, Ilana Hanes, Nathalie Marcal, Dong Han, Sonia P Rodrigues, Soo Yuen Leong, Jia Newcombe, Jack P Antel, Timothy E Kenned. Full-length and fragmented netrin-1 in multiple sclerosis plaques are inhibitors of oligodendrocyte precursor cell migration. The American journal of pathology. vol 183. issue 3. 2014-03-12. PMID:23831296. |
factors present in multiple sclerosis lesions are thought to inhibit oligodendrocyte precursor cell migration, limiting their recruitment to axons requiring remyelination; however, few inhibitors have been identified. |
2014-03-12 |
2023-08-12 |
human |
| Jenea M Bin, Sathyanath Rajasekharan, Tanja Kuhlmann, Ilana Hanes, Nathalie Marcal, Dong Han, Sonia P Rodrigues, Soo Yuen Leong, Jia Newcombe, Jack P Antel, Timothy E Kenned. Full-length and fragmented netrin-1 in multiple sclerosis plaques are inhibitors of oligodendrocyte precursor cell migration. The American journal of pathology. vol 183. issue 3. 2014-03-12. PMID:23831296. |
these findings indicate that full-length and fragmented forms of netrin-1, found in multiple sclerosis lesions, have the capacity to inhibit oligodendrocyte precursor migration, identifying netrin-1 as a potential target for therapies that promote remyelination. |
2014-03-12 |
2023-08-12 |
human |
| Sabine Pfeifenbring, Imke Metz, David Kremer, Patrick Küry, Hans-Peter Hartung, Wolfgang Brüc. Oligodendroglial lineage cells express nuclear p57kip2 in multiple sclerosis lesions. Glia. vol 61. issue 8. 2014-03-10. PMID:23828667. |
impaired remyelination in multiple sclerosis (ms) might be due to the failure of oligodendrocyte precursor cells (opc) to differentiate into myelinating oligodendrocytes. |
2014-03-10 |
2023-08-12 |
human |
| Sha Mi, R Blake Pepinsky, Diego Cadavi. Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic. CNS drugs. vol 27. issue 7. 2014-02-03. PMID:23681979. |
in humans, lingo-1 expression is increased in oligodendrocyte progenitor cells from demyelinated white matter of multiple sclerosis post-mortem samples, and in dopaminergic neurons from parkinson's disease brains. |
2014-02-03 |
2023-08-12 |
rat |
| Markus Reindl, Franziska Di Pauli, Kevin Rostásy, Thomas Berge. The spectrum of MOG autoantibody-associated demyelinating diseases. Nature reviews. Neurology. vol 9. issue 8. 2014-01-15. PMID:23797245. |
myelin oligodendrocyte glycoprotein (mog) has been identified as a target of demyelinating autoantibodies in animal models of inflammatory demyelinating diseases of the cns, such as multiple sclerosis (ms). |
2014-01-15 |
2023-08-12 |
human |
| Zizhen Kang, Chenhui Wang, Jarod Zepp, Ling Wu, Kevin Sun, Junjie Zhao, Unni Chandrasekharan, Paul E DiCorleto, Bruce D Trapp, Richard M Ransohoff, Xiaoxia L. Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells. Nature neuroscience. vol 16. issue 10. 2013-11-25. PMID:23995070. |
the sensitivity of oligodendrocyte lineage cells to il-17-mediated toxicity further suggests a direct link between inflammation and neurodegeneration in multiple sclerosis. |
2013-11-25 |
2023-08-12 |
mouse |
| Fadi J Najm, Angela M Lager, Anita Zaremba, Krysta Wyatt, Andrew V Caprariello, Daniel C Factor, Robert T Karl, Tadao Maeda, Robert H Miller, Paul J Tesa. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nature biotechnology. vol 31. issue 5. 2013-10-29. PMID:23584611. |
cell-based therapies for myelin disorders, such as multiple sclerosis and leukodystrophies, require technologies to generate functional oligodendrocyte progenitor cells. |
2013-10-29 |
2023-08-12 |
mouse |
| Qiao-Ling Cui, Tanja Kuhlmann, Veronique E Miron, Soo Yuen Leong, Jun Fang, Pavel Gris, Timothy E Kennedy, Guillermina Almazan, Jack Ante. Oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis. The American journal of pathology. vol 183. issue 2. 2013-10-24. PMID:23746653. |
oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis. |
2013-10-24 |
2023-08-12 |
human |