| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roni Lehmann-Werman, Daniel Neiman, Hai Zemmour, Joshua Moss, Judith Magenheim, Adi Vaknin-Dembinsky, Sten Rubertsson, Bengt Nellgård, Kaj Blennow, Henrik Zetterberg, Kirsty Spalding, Michael J Haller, Clive H Wasserfall, Desmond A Schatz, Carla J Greenbaum, Craig Dorrell, Markus Grompe, Aviad Zick, Ayala Hubert, Myriam Maoz, Volker Fendrich, Detlef K Bartsch, Talia Golan, Shmuel A Ben Sasson, Gideon Zamir, Aharon Razin, Howard Cedar, A M James Shapiro, Benjamin Glaser, Ruth Shemer, Yuval Do. Identification of tissue-specific cell death using methylation patterns of circulating DNA. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 13. 2016-09-01. PMID:26976580. |
pancreatic β-cell dna was identified in the circulation of patients with recently diagnosed type-1 diabetes and islet-graft recipients; oligodendrocyte dna was identified in patients with relapsing multiple sclerosis; neuronal/glial dna was identified in patients after traumatic brain injury or cardiac arrest; and exocrine pancreas dna was identified in patients with pancreatic cancer or pancreatitis. |
2016-09-01 |
2023-08-13 |
human |
| Ji-Eun Seo, Mahbub Hasan, Khandoker Asiqur Rahaman, Min-Jung Kang, Byung-Hwa Jung, Oh-Seung Kwo. A leading role for NADPH oxidase in an in-vitro study of experimental autoimmune encephalomyelitis. Molecular immunology. vol 72. 2016-08-23. PMID:26928315. |
myelin oligodendrocyte glycoprotein peptide fragment 35-55 (mog35-55) is a major autoantigen inducing experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis that is characterized by blood-brain barrier (bbb) disruption. |
2016-08-23 |
2023-08-13 |
Not clear |
| Jeffery D Haines, Oscar G Vidaurre, Fan Zhang, Ángela L Riffo-Campos, Josefa Castillo, Bonaventura Casanova, Patrizia Casaccia, Gerardo Lopez-Roda. Multiple sclerosis patient-derived CSF induces transcriptional changes in proliferating oligodendrocyte progenitors. Multiple sclerosis (Houndmills, Basingstoke, England). vol 21. issue 13. 2016-08-22. PMID:25948622. |
multiple sclerosis patient-derived csf induces transcriptional changes in proliferating oligodendrocyte progenitors. |
2016-08-22 |
2023-08-13 |
Not clear |
| Jeffery D Haines, Oscar G Vidaurre, Fan Zhang, Ángela L Riffo-Campos, Josefa Castillo, Bonaventura Casanova, Patrizia Casaccia, Gerardo Lopez-Roda. Multiple sclerosis patient-derived CSF induces transcriptional changes in proliferating oligodendrocyte progenitors. Multiple sclerosis (Houndmills, Basingstoke, England). vol 21. issue 13. 2016-08-22. PMID:25948622. |
cerebrospinal fluid (csf) is in contact with brain parenchyma and ventricles, and its composition might influence the cellular physiology of oligodendrocyte progenitor cells (opcs) thereby contributing to multiple sclerosis (ms) disease pathogenesis. |
2016-08-22 |
2023-08-13 |
Not clear |
| Osamu Imamura, Masaaki Arai, Minori Dateki, Toru Ogata, Ryuji Uchida, Hiroshi Tomoda, Kunio Takishim. Nicotinic acetylcholine receptors mediate donepezil-induced oligodendrocyte differentiation. Journal of neurochemistry. vol 135. issue 6. 2016-08-22. PMID:26315944. |
failure of myelin development and oligodendrocyte loss results in serious human disorders, including multiple sclerosis. |
2016-08-22 |
2023-08-13 |
human |
| Reinhard Hohlfeld, Klaus Dornmair, Edgar Meinl, Hartmut Wekerl. The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research. The Lancet. Neurology. vol 15. issue 3. 2016-08-09. PMID:26724102. |
myelin oligodendrocyte glycoprotein (mog) has received renewed attention as an antibody target in childhood multiple sclerosis and in a small subgroup of adult patients with multiple sclerosis. |
2016-08-09 |
2023-08-13 |
human |
| Ahdeah Pajoohesh-Ganji, Robert H Mille. Oligodendrocyte ablation as a tool to study demyelinating diseases. Neural regeneration research. vol 11. issue 6. 2016-08-02. PMID:27482202. |
multiple sclerosis (ms) is an autoimmune mediated neurodegenerative disease characterized by demyelination and oligodendrocyte (ol) loss in the central nervous system and accompanied by local inflammation and infiltration of peripheral immune cells. |
2016-08-02 |
2023-08-13 |
Not clear |
| Kavitha Kothur, Louise Wienholt, Esther M Tantsis, John Earl, Sushil Bandodkar, Kristina Prelog, Fiona Tea, Sudarshini Ramanathan, Fabienne Brilot, Russell C Dal. B Cell, Th17, and Neutrophil Related Cerebrospinal Fluid Cytokine/Chemokines Are Elevated in MOG Antibody Associated Demyelination. PloS one. vol 11. issue 2. 2016-07-26. PMID:26919719. |
myelin oligodendrocyte glycoprotein antibody (mog ab) associated demyelination represents a subgroup of autoimmune demyelination that is separate from multiple sclerosis and aquaporin 4 igg-positive nmo, and can have a relapsing course. |
2016-07-26 |
2023-08-13 |
Not clear |
| Melania Spadaro, Lisa Ann Gerdes, Markus Krumbholz, Birgit Ertl-Wagner, Franziska Sabrina Thaler, Elisabeth Schuh, Imke Metz, Astrid Blaschek, Andrea Dick, Wolfgang Brück, Reinhard Hohlfeld, Edgar Meinl, Tania Kümpfe. Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis. Neurology(R) neuroimmunology & neuroinflammation. vol 3. issue 5. 2016-07-26. PMID:27458601. |
to evaluate the presence of antibodies to conformation-intact myelin oligodendrocyte glycoprotein (mog) in a subgroup of adult patients with clinically definite multiple sclerosis (ms) preselected for a specific clinical phenotype including severe spinal cord, optic nerve, and brainstem involvement. |
2016-07-26 |
2023-08-13 |
Not clear |
| Dae-Kwon Bae, Dongsun Park, Sun Hee Lee, Goeun Yang, Jangbeen Kyung, Dajeong Kim, Kyungha Shin, Ehn-Kyoung Choi, Gonhyung Kim, Jin Tae Hong, Seung U Kim, Yun-Bae Ki. Comparative Effects of Human Neural Stem Cells and Oligodendrocyte Progenitor Cells on the Neurobehavioral Disorders of Experimental Autoimmune Encephalomyelitis Mice. Stem cells international. vol 2016. 2016-07-19. PMID:27429621. |
since multiple sclerosis (ms) is featured with widespread demyelination caused by autoimmune response, we investigated the recovery effects of f3.olig2 progenitors, established by transducing human neural stem cells (f3 nscs) with olig2 transcription factor, in myelin oligodendrocyte glycoprotein- (mog-) induced experimental autoimmune encephalomyelitis (eae) model mice. |
2016-07-19 |
2023-08-13 |
mouse |
| Ben J Gu, Judith Field, Sébastien Dutertre, Amber Ou, Trevor J Kilpatrick, Jeannette Lechner-Scott, Rodney Scott, Rodney Lea, Bruce V Taylor, Jim Stankovich, Helmut Butzkueven, Melissa Gresle, Simon M Laws, Steven Petrou, Sabine Hoffjan, Denis A Akkad, Colin A Graham, Stanley Hawkins, Anna Glaser, Sahl Khalid Bedri, Jan Hillert, Carlos Matute, Alfredo Antiguedad, James S Wile. A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis. Human molecular genetics. vol 24. issue 19. 2016-07-06. PMID:26188005. |
multiple sclerosis (ms) is a chronic relapsing-remitting inflammatory disease of the central nervous system characterized by oligodendrocyte damage, demyelination and neuronal death. |
2016-07-06 |
2023-08-13 |
human |
| Bangfu Zhu, Chao Zhao, Fraser I Young, Robin J M Franklin, Bing Son. Isolation and long-term expansion of functional, myelinating oligodendrocyte progenitor cells from neonatal rat brain. Current protocols in stem cell biology. vol 31. 2016-06-27. PMID:25366898. |
the isolation of purified oligodendrocyte progenitor cells (opcs) in large numbers has been sought after as a source of cells for repair following cns-demyelinating diseases and injuries, such as multiple sclerosis (ms) and spinal cord injury (sci). |
2016-06-27 |
2023-08-13 |
rat |
| Giampiero Porcu, Eliseo Serone, Velia De Nardis, Daniele Di Giandomenico, Giuseppe Lucisano, Marco Scardapane, Anna Poma, Antonella Ragnini-Wilso. Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor Activation. PloS one. vol 10. issue 12. 2016-06-27. PMID:26658258. |
one of the causes of permanent disability in chronic multiple sclerosis patients is the inability of oligodendrocyte progenitor cells (opcs) to terminate their maturation program at lesions. |
2016-06-27 |
2023-08-13 |
mouse |
| Steven A Goldman, Nicholas J Kuyper. How to make an oligodendrocyte. Development (Cambridge, England). vol 142. issue 23. 2016-05-26. PMID:26628089. |
oligodendrocyte loss results in demyelination, which leads to impaired neurological function in a broad array of diseases ranging from pediatric leukodystrophies and cerebral palsy, to multiple sclerosis and white matter stroke. |
2016-05-26 |
2023-08-13 |
Not clear |
| Maria Traka, Joseph R Podojil, Derrick P McCarthy, Stephen D Miller, Brian Popk. Oligodendrocyte death results in immune-mediated CNS demyelination. Nature neuroscience. vol 19. issue 1. 2016-05-26. PMID:26656646. |
overall, these data indicate that oligodendrocyte death is sufficient to trigger an adaptive autoimmune response against myelin, suggesting that a similar process can occur in the pathogenesis of multiple sclerosis. |
2016-05-26 |
2023-08-13 |
mouse |
| Melania Spadaro, Edgar Mein. Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases. Methods in molecular biology (Clifton, N.J.). vol 1304. 2016-05-05. PMID:25814289. |
detection of autoantibodies against myelin oligodendrocyte glycoprotein in multiple sclerosis and related diseases. |
2016-05-05 |
2023-08-13 |
Not clear |
| Melania Spadaro, Edgar Mein. Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases. Methods in molecular biology (Clifton, N.J.). vol 1304. 2016-05-05. PMID:25814289. |
autoantibodies against myelin oligodendrocyte glycoprotein (mog) occur in a proportion of patients with different inflammatory demyelinating diseases of the central nervous system, such as childhood multiple sclerosis (ms), acute disseminated encephalomyelitis (adem), and neuromyelitis optica spectrum disorders (nmosd). |
2016-05-05 |
2023-08-13 |
Not clear |
| Alison Ruth Jennings, William M Carrol. Oligodendrocyte Lineage Cells in Chronic Demyelination of Multiple Sclerosis Optic Nerve. Brain pathology (Zurich, Switzerland). vol 25. issue 5. 2016-05-04. PMID:25175564. |
oligodendrocyte lineage cells in chronic demyelination of multiple sclerosis optic nerve. |
2016-05-04 |
2023-08-13 |
human |
| Alison Ruth Jennings, William M Carrol. Oligodendrocyte Lineage Cells in Chronic Demyelination of Multiple Sclerosis Optic Nerve. Brain pathology (Zurich, Switzerland). vol 25. issue 5. 2016-05-04. PMID:25175564. |
reports that chronically demyelinated multiple sclerosis brain and spinal cord lesions contained immature oligodendrocyte lineage cells have generated major interest aimed at the potential for promotion of endogenous repair. |
2016-05-04 |
2023-08-13 |
human |
| Alison Ruth Jennings, William M Carrol. Oligodendrocyte Lineage Cells in Chronic Demyelination of Multiple Sclerosis Optic Nerve. Brain pathology (Zurich, Switzerland). vol 25. issue 5. 2016-05-04. PMID:25175564. |
it was found that some chronically demyelinated multiple sclerosis optic nerve lesions contained oligodendroglial cells and that heterogeneity existed in the presence of myelin sheaths, oligodendrocyte maturational stages and extent of axonal investment. |
2016-05-04 |
2023-08-13 |
human |