Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Noor Z Al Dahhan, Julie Tseng, Cynthia de Medeiros, Sridar Narayanan, Douglas L Arnold, Brian C Coe, Douglas P Munoz, E Ann Yeh, Donald J Mabbot. Compensatory mechanisms amidst demyelinating disorders: insights into cognitive preservation. Brain communications. vol 6. issue 6. 2024-11-14. PMID:39534724. |
demyelination disrupts the transmission of electrical signals in the brain and affects neurodevelopment in children with disorders such as multiple sclerosis and myelin oligodendrocyte glycoprotein-associated disorders. |
2024-11-14 |
2024-11-17 |
human |
Noor Z Al Dahhan, Julie Tseng, Cynthia de Medeiros, Sridar Narayanan, Douglas L Arnold, Brian C Coe, Douglas P Munoz, E Ann Yeh, Donald J Mabbot. Compensatory mechanisms amidst demyelinating disorders: insights into cognitive preservation. Brain communications. vol 6. issue 6. 2024-11-14. PMID:39534724. |
28 typically developing children, 18 children with multiple sclerosis and 14 children with myelin oligodendrocyte glycoprotein-associated disorders between 5 and 18.9 years old were scanned at the hospital for sick children. |
2024-11-14 |
2024-11-17 |
human |
Noor Z Al Dahhan, Julie Tseng, Cynthia de Medeiros, Sridar Narayanan, Douglas L Arnold, Brian C Coe, Douglas P Munoz, E Ann Yeh, Donald J Mabbot. Compensatory mechanisms amidst demyelinating disorders: insights into cognitive preservation. Brain communications. vol 6. issue 6. 2024-11-14. PMID:39534724. |
children diagnosed with multiple sclerosis had greater structural compromise relative to children with myelin oligodendrocyte glycoprotein-associated disorders; there were no group differences in neural synchrony. |
2024-11-14 |
2024-11-17 |
human |
Yingqiu Song, Yanhui Peng, Bing Wang, Xinyue Zhou, Yikang Cai, Haiyong Chen, Chenggui Mia. The roles of pyroptosis in the pathogenesis of autoimmune diseases. Life sciences. 2024-11-13. PMID:39537097. |
in multiple sclerosis (ms), elevated active caspase-11 in primary astrocytes induces oligodendrocyte pyroptosis, advancing ms progression. |
2024-11-13 |
2024-11-17 |
Not clear |
Hao Xu, Huiyuan Zhang, Nona Pop, Joe Hall, Ibrahim Shazlee, Moritz Wagner-Tsukamoto, Zhiguo Chen, Yuchun Gu, Chao Zhao, Dan M. The isoflavone puerarin promotes generation of human iPSC-derived pre-oligodendrocytes and enhances endogenous remyelination in rodent models. Journal of neurochemistry. 2024-10-18. PMID:39424593. |
myelin damage in diseases such as multiple sclerosis (ms) and ischemia induces activation of endogenous oligodendrocyte progenitor cells (opc) and subsequent remyelination by newly formed oligodendrocytes. |
2024-10-18 |
2024-10-21 |
mouse |
Fumitaka Shimizu, Masayuki Nakamor. Blood-Brain Barrier Disruption in Neuroimmunological Disease. International journal of molecular sciences. vol 25. issue 19. 2024-10-16. PMID:39408955. |
this review highlights the pathological contribution of bbb dysfunction to neuroimmunological diseases, including multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd), myelin oligodendrocyte glycoprotein antibody-associated disease (mogad), autoimmune encephalitis (ae), and paraneoplastic neurological syndrome (pns). |
2024-10-16 |
2024-10-18 |
Not clear |
Ann-Kathrin Kogel, Theodoros Ladopoulos, Carolin Schwake, Ingo Kleiter, Bianca Teegen, Nadine Siems, Christian Prehn, Solveig Lichtenberg, Marius Ringelstein, Orhan Aktas, Refik Pul, Britta Krieger, Carsten Lukas, Iris-Katharina Penner, Ralf Gold, Ruth Schneider, Ilya Ayzenber. Cognitive Impairment, Associated Clinical Factors, and MR Volumetric Measures in Myelin Oligodendrocyte Glycoprotein-IgG-Associated Disease. Neurology(R) neuroimmunology & neuroinflammation. vol 11. issue 6. 2024-10-11. PMID:39393044. |
cognitive impairment is a common and challenging symptom in multiple sclerosis and neuromyelitis optica spectrum disease; however, data in myelin oligodendrocyte glycoprotein-igg-associated disease (mogad) remain scarce. |
2024-10-11 |
2024-10-14 |
Not clear |
Norihisa Bizen, Hirohide Takebayash. Diverse functions of DEAD-box proteins in oligodendrocyte development, differentiation, and homeostasis. Journal of neurochemistry. 2024-10-07. PMID:39374171. |
the dysregulation of oligodendrocyte differentiation and homeostasis have been implicated in a wide range of neurological diseases, including dysmyelinating disorders (e.g., pelizaeus-merzbacher disease), demyelinating diseases (e.g., multiple sclerosis), alzheimer's disease, and psychiatric disorders. |
2024-10-07 |
2024-10-10 |
Not clear |
Michael Eyre, Michael Absoud, Omar Abdel-Mannan, Sarah Crichton, Yael Hacohen, Thomas Rossor, Sarah Rudebeck, Gavin Giovannoni, Ming Lim, Cheryl Hemingwa. Academic outcomes before and after clinical onset of acquired demyelinating syndromes in children: a matched cohort data linkage study. Annals of clinical and translational neurology. 2024-10-03. PMID:39359055. |
we conducted a matched cohort study using prospectively collected educational data in multiple sclerosis (ms) and myelin oligodendrocyte glycoprotein antibody disease (mogad) patients (n = 60) and controls (pooled n = 449,553). |
2024-10-03 |
2024-10-05 |
Not clear |
T J Hartung, F Bartels, J Kuchling, S Krohn, J Leidel, M Mantwill, K Wurdack, S Yogeshwar, M Scheel, C Fink. MRI findings in autoimmune encephalitis. Revue neurologique. 2024-10-02. PMID:39358087. |
in some nmda receptor encephalitis cases, these t2-hyperintense lesions may be indicative of an nmda receptor encephalitis overlap syndrome with simultaneous co-existence of multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd) or myelin oligodendrocyte glycoprotein antibody-associated disease (mogad). |
2024-10-02 |
2024-10-05 |
Not clear |
Jagannadha Avasarala, Christopher McLouth, Abusamra Khawla, Paul Wilkerson, Ellen Anderson-Benge, Karen B Lundgren, Saurav Da. Preliminary findings of a 'test bundle' to accelerate the diagnosis of MS and NMOSD following optic neuritis. Multiple sclerosis and related disorders. vol 91. 2024-09-26. PMID:39326210. |
no study has investigated the length of time it takes to diagnose multiple sclerosis (ms) or neuromyelitis optic spectrum disorder (nmosd, aquaporin 4 antibody disease or myelin oligodendrocyte glycoprotein antibody disease, mogad) following the onset of de novo optic neuritis (on). |
2024-09-26 |
2024-09-29 |
Not clear |
Paola Perini, Marta Gaggiola, Francesca Rinaldi, Paolo Gallo, Marco Puthenparampi. Relapsing tumefactive demyelination lesions: A unique, distinct inflammatory brain pathology. Multiple sclerosis (Houndmills, Basingstoke, England). 2024-09-09. PMID:39245942. |
our case supports the view that recurrent tdl is a relapsing brain inflammation not belonging to multiple sclerosis (ms) or myelin oligodendrocyte glycoprotein (mog)-/aqp4-associated disorders. |
2024-09-09 |
2024-09-11 |
Not clear |
Giulia Fadda, Brenda Banwell, Colm Elliott, Dumitru Fetco, Douglas L Arnold, Patrick Waters, E Ann Yeh, Ruth Ann Marrie, Amit Bar-Or, Sridar Narayana. Slowly Expanding Lesions Differentiate Pediatric Multiple Sclerosis from Myelin Oligodendrocyte Glycoprotein Antibody Disease. Annals of neurology. 2024-09-07. PMID:39243229. |
slowly expanding lesions differentiate pediatric multiple sclerosis from myelin oligodendrocyte glycoprotein antibody disease. |
2024-09-07 |
2024-09-10 |
human |
Li-Tal Pratt, Hadas Meirson, Mika Shapira Rootman, Liat Ben-Sira, Shelly I Shira. Radiological features in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease-diagnostic criteria and lesion dynamics. Pediatric radiology. 2024-09-07. PMID:39243314. |
the spectrum of acquired pediatric demyelinating syndromes has been expanding over the past few years, to include myelin oligodendrocyte glycoprotein antibody-associated disease (mogad), as a distinct neuroimmune entity, in addition to pediatric-onset multiple sclerosis (poms) and aquaporin 4-igg-seropositive neuromyelitis optica spectrum disorder (aqp4+nmosd). |
2024-09-07 |
2024-09-10 |
Not clear |
Chen Chen, Yaqing Shu, Chengkai Yan, Huilu Li, Zhenchao Huang, ShiShi Shen, Chunxin Liu, Yanjun Jiang, Shixiong Huang, Zhanhang Wang, Feng Mei, Feng Qin, Xiaodong Liu, Wei Qi. Astrocyte-derived clusterin disrupts glial physiology to obstruct remyelination in mouse models of demyelinating diseases. Nature communications. vol 15. issue 1. 2024-09-06. PMID:39242637. |
multiple sclerosis (ms) is a debilitating demyelinating disease characterized by remyelination failure attributed to inadequate oligodendrocyte precursor cells (opcs) differentiation and aberrant astrogliosis. |
2024-09-06 |
2024-09-10 |
mouse |
Z Smith, V T Cheli, C G Angeliu, C Wang, G E Denaroso, S G Tumuluri, J Corral, K Garbarini, P M Pae. Ferritin loss in astrocytes reduces spinal cord oxidative stress and demyelination in the experimental autoimmune encephalomyelitis (EAE) model. Glia. 2024-09-04. PMID:39228110. |
demyelinating diseases such as multiple sclerosis (ms) cause myelin degradation and oligodendrocyte death, resulting in the release of toxic iron and iron-induced oxidative stress. |
2024-09-04 |
2024-09-06 |
mouse |
Giulio Volpe, Neringa Jurkute, Gabriela Girafa, Hanna G Zimmermann, Seyedamirhosein Motamedi, Charlotte Bereuter, Lekha Pandit, Anitha D'Cunha, Michael R Yeaman, Terry J Smith, Lawrence J Cook, Alexander U Brandt, Friedemann Paul, Axel Petzold, Frederike C Oerte. Diagnostic Value of Inter-Eye Difference Metrics on OCT for Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis. Neurology(R) neuroimmunology & neuroinflammation. vol 11. issue 6. 2024-09-04. PMID:39231384. |
the diagnostic value of intereye difference (ied) metrics is high for on in patients with multiple sclerosis and aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders, but unknown in myelin oligodendrocyte glycoprotein antibody-associated on (mog-on). |
2024-09-04 |
2024-09-08 |
Not clear |
Ruth Geraldes, Georgina Arrambide, Brenda Banwell, Àlex Rovira, Rosa Cortese, Hans Lassmann, Silvia Messina, Mara Assunta Rocca, Patrick Waters, Declan Chard, Claudio Gasperini, Yael Hacohen, Romina Mariano, Friedemann Paul, Gabriele C DeLuca, Christian Enzinger, Ludwig Kappos, M Isabel Leite, Jaume Sastre-Garriga, Tarek Yousry, Olga Ciccarelli, Massimo Filippi, Frederik Barkhof, Jacqueline Palac. The influence of MOGAD on diagnosis of multiple sclerosis using MRI. Nature reviews. Neurology. 2024-09-03. PMID:39227463. |
myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) is an immune-mediated demyelinating disease that is challenging to differentiate from multiple sclerosis (ms), as the clinical phenotypes overlap, and people with mogad can fulfil the current mri-based diagnostic criteria for ms. |
2024-09-03 |
2024-09-06 |
Not clear |
Tarun Sharma, Sidharth Mehan, Aarti Tiwari, Zuber Khan, Ghanshyam Das Gupta, Acharan S Narul. Targeting Oligodendrocyte Dynamics and Remyelination: Emerging Therapies and Personalized Approaches in Multiple Sclerosis Management. Current neurovascular research. 2024-09-02. PMID:39219420. |
targeting oligodendrocyte dynamics and remyelination: emerging therapies and personalized approaches in multiple sclerosis management. |
2024-09-02 |
2024-09-04 |
Not clear |
Amber R Philp, Carolina R Reyes, Josselyne Mansilla, Amar Sharma, Chao Zhao, Carlos Valenzuela-Krugmann, Khalil S Rawji, Ginez A Gonzalez Martinez, Penelope Dimas, Bryan Hinrichsen, César Ulloa-Leal, Amie K Waller, Diana M Bessa de Sousa, Maite A Castro, Ludwig Aigner, Pamela Ehrenfeld, Maria Elena Silva, Ilias Kazanis, Cedric Ghevaert, Robin J M Franklin, Francisco J River. Circulating platelets modulate oligodendrocyte progenitor cell differentiation during remyelination. eLife. vol 12. 2024-08-20. PMID:39163103. |
revealing unknown cues that regulate oligodendrocyte progenitor cell (opc) function in remyelination is important to optimise the development of regenerative therapies for multiple sclerosis (ms). |
2024-08-20 |
2024-08-22 |
mouse |