| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niroshan Jeyakumar, Magdalena Lerch, Russell C Dale, Sudarshini Ramanatha. MOG antibody-associated optic neuritis. Eye (London, England). 2024-05-23. PMID:38783085. |
myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) is a demyelinating disorder, distinct from multiple sclerosis (ms) and neuromyelitis optica spectrum disorder (nmosd). |
2024-05-23 |
2024-05-27 |
Not clear |
| Y Labrak, M Alhouayek, A Mwema, L d'Auria, B Ucakar, V van Pesch, G G Muccioli, A des Rieu. The combined administration of LNC-encapsulated retinoic acid and calcitriol stimulates oligodendrocyte progenitor cell differentiation in vitro and in vivo after intranasal administration. International journal of pharmaceutics. 2024-05-18. PMID:38762167. |
as the hallmarks of multiple sclerosis (ms) are neuroinflammation and oligodendrocyte loss, our hypothesis was that by combining two molecules known for their pro-differentiating properties, encapsulated in lnc, and delivered by intranasal administration, we would stimulate oligodendrocyte progenitor cells (opc) differentiation into oligodendrocytes and provide a new pro-remyelinating therapy. |
2024-05-18 |
2024-05-27 |
mouse |
| Roopa Ravichandar, Farah Gadelkarim, Rupadevi Muthaiah, Nicolas Glynos, Kateryna Murlanova, Nagendra K Rai, Darpan Saraswat, Jessie J Polanco, Ranjan Dutta, Dinesh Pal, Fraser J Si. Dysregulated cholinergic signaling inhibits oligodendrocyte maturation following demyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-05-15. PMID:38749703. |
dysregulation of oligodendrocyte progenitor cell (opc) recruitment and oligodendrocyte differentiation contribute to failure of remyelination in human demyelinating diseases such as multiple sclerosis (ms). |
2024-05-15 |
2024-05-27 |
mouse |
| Ritu R Trivedi, Angela S Archambault, Clarice Pavlak, Matteo Gastaldi, Claudia Cantoni, Laura Ghezzi, Anne H Cross, Timothy M Miller, Gregory F W. Prevalence of anti-myelin oligodendrocyte glycoprotein antibodies across neuroinflammatory and neurodegenerative diseases. Journal of the neurological sciences. vol 461. 2024-05-14. PMID:38744216. |
inflammatory central nervous system (cns) diseases, such as multiple sclerosis (ms) and myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad), are characterized by humoral immune abnormalities. |
2024-05-14 |
2024-05-27 |
human |
| Tapio Nevalainen, Arttu Autio-Kimura, Mikko Hurm. Human endogenous retrovirus W in multiple sclerosis: transcriptional activity is associated with decline in oligodendrocyte proportions in the white matter of the brain. Journal of neurovirology. 2024-05-08. PMID:38717678. |
human endogenous retrovirus w in multiple sclerosis: transcriptional activity is associated with decline in oligodendrocyte proportions in the white matter of the brain. |
2024-05-08 |
2024-05-27 |
human |
| Ramakrishna Prithviraj, Bidisha Banerjee, Ullas V Acharya, Muhammed Hafis, Sruthi Sashidhara. Clinico-radiologic Spectrum and Outcome of Pediatric Acquired Demyelinating Disorders of Central Nervous System: A Retrospective Indian Tertiary Care Hospital Cohort. Neuropediatrics. 2024-05-07. PMID:38641336. |
we describe clinico-radiologic spectrum, outcomes, and comparison of the groups: acute disseminated encephalomyelitis (adem), neuromyelitis optica spectrum disorder (nmosd), clinically isolated syndrome (cis), multiple sclerosis (ms), and myelin oligodendrocyte glycoprotein antibody-associated disorders (mogad). |
2024-05-07 |
2024-05-27 |
Not clear |
| Laura Cacciaguerra, Omar Abdel-Mannan, Dimitrios Champsas, Kshitij Mankad, Karl N Krecke, John J Chen, Stephanie B Syc-Mazurek, Vyanka Redenbaugh, Alfonso S Lopez-Chiriboga, Cristina Valencia-Sanchez, Cheryl Hemingway, Jan-Mendelt Tillema, Olga Ciccarelli, Sean J Pittock, Yael Hacohen, Eoin P Flanaga. Radiologic Lag and Brain MRI Lesion Dynamics During Attacks in MOG Antibody-Associated Disease. Neurology. vol 102. issue 10. 2024-05-06. PMID:38710000. |
we evaluated intra-attack lesion dynamics in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) vs multiple sclerosis (ms) and aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder (aqp4+nmosd). |
2024-05-06 |
2024-05-27 |
Not clear |
| Xuezhao Liu, Dazhuan Eric Xin, Xiaowen Zhong, Chuntao Zhao, Zhidan Li, Liguo Zhang, Adam J Dourson, Lindsay Lee, Shreya Mishra, Arman E Bayat, Eva Nicholson, William L Seibel, Bingfang Yan, Joel Mason, Bradley J Turner, David G Gonsalvez, William Ong, Sing Yian Chew, Balaram Ghosh, Sung Ok Yoon, Mei Xin, Zhigang He, Jason Tchieu, Michael Wegner, Klaus-Armin Nave, Robin J M Franklin, Ranjan Dutta, Bruce D Trapp, Ming Hu, Matthew A Smith, Michael P Jankowski, Samantha K Barton, Xuelian He, Q Richard L. Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration. Cell. 2024-05-03. PMID:38701782. |
remyelination failure in diseases like multiple sclerosis (ms) was thought to involve suppressed maturation of oligodendrocyte precursors; however, oligodendrocytes are present in ms lesions yet lack myelin production. |
2024-05-03 |
2024-05-06 |
mouse |
| Alessia Bianchi, Rosa Cortese, Ferran Prados, Carmen Tur, Baris Kanber, Marios C Yiannakas, Rebecca Samson, Floriana De Angelis, Lise Magnollay, Anu Jacob, Wallace Brownlee, Anand Trip, Richard Nicholas, Yael Hacohen, Frederik Barkhof, Olga Ciccarelli, Ahmed T Toos. Optic chiasm involvement in multiple sclerosis, aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein-associated disease. Multiple sclerosis (Houndmills, Basingstoke, England). 2024-04-22. PMID:38646958. |
optic neuritis (on) is a common feature of inflammatory demyelinating diseases (idds) such as multiple sclerosis (ms), aquaporin 4-antibody neuromyelitis optica spectrum disorder (aqp4 + nmosd) and myelin oligodendrocyte glycoprotein antibody-associated disease (mogad). |
2024-04-22 |
2024-04-26 |
Not clear |
| Noah J Spillers, Patrick M Luther, Norris C Talbot, Evan J Kidder, Connor A Doyle, Salim C Lutfallah, Alyssa G Derouen, Sridhar Tirumala, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye, Giustino Varrass. A Comparative Review of Typical and Atypical Optic Neuritis: Advancements in Treatments, Diagnostics, and Prognosis. Cureus. vol 16. issue 3. 2024-04-15. PMID:38618469. |
herein, we examine the differences in presentation, pathophysiology, and treatments of typical on causes, like multiple sclerosis (ms), and atypical causes such as neuromyelitis optica spectrum disorder (nmosd) and myelin oligodendrocyte glycoprotein (mog)-immunoglobulin g (igg) on. |
2024-04-15 |
2024-04-17 |
Not clear |
| S Jarius, M Ringelstein, K Schanda, K Ruprecht, M Korporal-Kuhnke, A Viehöver, M W Hümmert, P Schindler, V Endmayr, M Gastaldi, C Trebst, D Franciotta, O Aktas, R Höftberger, J Haas, L Komorowski, F Paul, M Reindl, B Wildeman. Improving the sensitivity of myelin oligodendrocyte glycoprotein-antibody testing: exclusive or predominant MOG-IgG3 seropositivity-a potential diagnostic pitfall in patients with MOG-EM/MOGAD. Journal of neurology. 2024-04-12. PMID:38609667. |
myelin oligodendrocyte glycoprotein antibody-associated encephalomyelitis (mog-em; also termed mog antibody-associated disease, mogad) is the most important differential diagnosis of both multiple sclerosis and neuromyelitis optica spectrum disorders. |
2024-04-12 |
2024-04-15 |
Not clear |
| Mohsen Sharifi-Kelishadi, Leila Zare, Yaghoub Fathollahi, Mohammad Java. Conversion of Astrocyte Cell Lines to Oligodendrocyte Progenitor Cells Using Small Molecules and Transplantation to Animal Model of Multiple Sclerosis. Journal of molecular neuroscience : MN. vol 74. issue 2. 2024-04-09. PMID:38594388. |
conversion of astrocyte cell lines to oligodendrocyte progenitor cells using small molecules and transplantation to animal model of multiple sclerosis. |
2024-04-09 |
2024-04-12 |
mouse |
| Shitiz Sriwastava, Mahmoud Elkhooly, Suban Amatya, Kriti Shrestha, Yusuf Kagzi, Dipika Bhatia, Rajesh Gupta, Shruti Jaiswal, Robert P Lisa. Recent advances in the treatment of primary and secondary progressive Multiple Sclerosis. Journal of neuroimmunology. vol 390. 2024-03-30. PMID:38554666. |
the article highlights upcoming potential treatments, which target different phases of inflammation and offer remyelinating strategies as well as direct and indirect neuroprotective and oligodendrocyte protective effects, providing a hopeful outlook for patients with primary and secondary progressive multiple sclerosis (ppms and spms). |
2024-03-30 |
2024-04-02 |
Not clear |
| Océane Perdaens, Pauline Bottemanne, Vincent van Pesc. MicroRNAs dysregulated in multiple sclerosis affect the differentiation of CG-4 cells, an oligodendrocyte progenitor cell line. Frontiers in cellular neuroscience. vol 18. 2024-03-15. PMID:38486710. |
micrornas dysregulated in multiple sclerosis affect the differentiation of cg-4 cells, an oligodendrocyte progenitor cell line. |
2024-03-15 |
2024-03-17 |
Not clear |
| Esmaeil Yazdanpanah, Sepehr Dadfar, Alireza Shadab, Niloufar Orooji, MohammadHossein Nemati, Alireza Pazoki, Seyed-Alireza Esmaeili, Rasoul Baharlou, Dariush Haghmora. Berberine: A natural modulator of immune cells in multiple sclerosis. Immunity, inflammation and disease. vol 12. issue 3. 2024-03-13. PMID:38477663. |
multiple sclerosis (ms) is a chronic disabling and neurodegenerative disease of the central nervous system (cns) characterized by the recruitment of autoreactive t cells into the cns causing demyelination, axonal damage, and oligodendrocyte loss. |
2024-03-13 |
2024-03-15 |
Not clear |
| Ruth Dorel, Dawei Sun, Nicholas Carruthers, Georgette M Castanedo, Peter M-U Ung, Daniel C Factor, Tianbo Li, Hannah Baumann, Danielle Janota, Jodie Pang, Laurent Salphati, Robert Meklemburg, Allison J Korman, Halie E Harper, Samantha Stubblefield, Jian Payandeh, Daniel McHugh, Bradley T Lang, Paul J Tesar, Edward Dere, Matthieu Masureel, Drew J Adams, Matthew Volgraf, Marie-Gabrielle Brau. Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation. Journal of medicinal chemistry. 2024-03-12. PMID:38470227. |
the inhibition of emopamil binding protein (ebp), a sterol isomerase within the cholesterol biosynthesis pathway, promotes oligodendrocyte formation, which has been proposed as a potential therapeutic approach for treating multiple sclerosis. |
2024-03-12 |
2024-03-14 |
Not clear |
| Ahmed N Abdallah, Ashraf A Shamaa, Omar S El-Tookhy, Mohamed M Bah. Comparison between stem cell therapy and stem cell derived exosomes on induced multiple sclerosis in dogs. BMC veterinary research. vol 20. issue 1. 2024-03-08. PMID:38459498. |
multiple sclerosis (ms) is a chronic condition that primarily manifests as demyelination of neuronal axons in the central nervous system, due to the loss or attack of oligodendroglia cells that form myelin. |
2024-03-08 |
2024-03-11 |
Not clear |
| Özdem Ertürk Çetin, İpek Güngör Doğan, Ümit Zanapalioğlu, Feyzullah Yadi, Damla Çetinkaya Tezer, Serkan Demi. Seizures in inflammatory demyelinating disorders of the central nervous system. Multiple sclerosis and related disorders. vol 85. 2024-03-07. PMID:38452647. |
multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd), and myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) may be associated with acute symptomatic seizures and chronic epilepsy as well. |
2024-03-07 |
2024-03-10 |
Not clear |
| Hamid Askari, Fatemeh Rabiei, Fatemeh Lohrasbi, Sara Ghadir, Ahmad Mehdipour Arbastan, Maryam Ghasemi-Kasma. AMP-activated protein kinase as a mediator of mitochondrial dysfunction of multiple sclerosis in animal models: A systematic review. Journal of cellular physiology. 2024-02-26. PMID:38403972. |
multiple sclerosis (ms) is a chronic central nervous system (cns) disorder characterized by demyelination, neuronal damage, and oligodendrocyte depletion. |
2024-02-26 |
2024-02-28 |
Not clear |
| Adam Goldman-Yassen, Azalea Lee, Grace Gombola. Leptomeningeal Enhancement in Pediatric Anti-Myelin Oligodendrocyte Glycoprotein Antibody Disease, Multiple Sclerosis, and Neuromyelitis Optica Spectrum Disorder. Pediatric neurology. vol 153. 2024-02-21. PMID:38382244. |
anti-myelin oligodendrocyte glycoprotein (mog) antibody disease (mogad) is a type of acquired demyelinating disease that is distinct from multiple sclerosis (ms) and aquaporin-4 antibody neuromyelitis optica spectrum disorder (aqp4-nmosd). |
2024-02-21 |
2024-02-24 |
Not clear |