Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Esmaeil Yazdanpanah, Sepehr Dadfar, Alireza Shadab, Niloufar Orooji, MohammadHossein Nemati, Alireza Pazoki, Seyed-Alireza Esmaeili, Rasoul Baharlou, Dariush Haghmora. Berberine: A natural modulator of immune cells in multiple sclerosis. Immunity, inflammation and disease. vol 12. issue 3. 2024-03-13. PMID:38477663. |
multiple sclerosis (ms) is a chronic disabling and neurodegenerative disease of the central nervous system (cns) characterized by the recruitment of autoreactive t cells into the cns causing demyelination, axonal damage, and oligodendrocyte loss. |
2024-03-13 |
2024-03-15 |
Not clear |
Ruth Dorel, Dawei Sun, Nicholas Carruthers, Georgette M Castanedo, Peter M-U Ung, Daniel C Factor, Tianbo Li, Hannah Baumann, Danielle Janota, Jodie Pang, Laurent Salphati, Robert Meklemburg, Allison J Korman, Halie E Harper, Samantha Stubblefield, Jian Payandeh, Daniel McHugh, Bradley T Lang, Paul J Tesar, Edward Dere, Matthieu Masureel, Drew J Adams, Matthew Volgraf, Marie-Gabrielle Brau. Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation. Journal of medicinal chemistry. 2024-03-12. PMID:38470227. |
the inhibition of emopamil binding protein (ebp), a sterol isomerase within the cholesterol biosynthesis pathway, promotes oligodendrocyte formation, which has been proposed as a potential therapeutic approach for treating multiple sclerosis. |
2024-03-12 |
2024-03-14 |
Not clear |
Ahmed N Abdallah, Ashraf A Shamaa, Omar S El-Tookhy, Mohamed M Bah. Comparison between stem cell therapy and stem cell derived exosomes on induced multiple sclerosis in dogs. BMC veterinary research. vol 20. issue 1. 2024-03-08. PMID:38459498. |
multiple sclerosis (ms) is a chronic condition that primarily manifests as demyelination of neuronal axons in the central nervous system, due to the loss or attack of oligodendroglia cells that form myelin. |
2024-03-08 |
2024-03-11 |
Not clear |
Özdem Ertürk Çetin, İpek Güngör Doğan, Ümit Zanapalioğlu, Feyzullah Yadi, Damla Çetinkaya Tezer, Serkan Demi. Seizures in inflammatory demyelinating disorders of the central nervous system. Multiple sclerosis and related disorders. vol 85. 2024-03-07. PMID:38452647. |
multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd), and myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) may be associated with acute symptomatic seizures and chronic epilepsy as well. |
2024-03-07 |
2024-03-10 |
Not clear |
Hamid Askari, Fatemeh Rabiei, Fatemeh Lohrasbi, Sara Ghadir, Ahmad Mehdipour Arbastan, Maryam Ghasemi-Kasma. AMP-activated protein kinase as a mediator of mitochondrial dysfunction of multiple sclerosis in animal models: A systematic review. Journal of cellular physiology. 2024-02-26. PMID:38403972. |
multiple sclerosis (ms) is a chronic central nervous system (cns) disorder characterized by demyelination, neuronal damage, and oligodendrocyte depletion. |
2024-02-26 |
2024-02-28 |
Not clear |
Adam Goldman-Yassen, Azalea Lee, Grace Gombola. Leptomeningeal Enhancement in Pediatric Anti-Myelin Oligodendrocyte Glycoprotein Antibody Disease, Multiple Sclerosis, and Neuromyelitis Optica Spectrum Disorder. Pediatric neurology. vol 153. 2024-02-21. PMID:38382244. |
anti-myelin oligodendrocyte glycoprotein (mog) antibody disease (mogad) is a type of acquired demyelinating disease that is distinct from multiple sclerosis (ms) and aquaporin-4 antibody neuromyelitis optica spectrum disorder (aqp4-nmosd). |
2024-02-21 |
2024-02-24 |
Not clear |
Florian Pernin, Qiao-Ling Cui, Abdulshakour Mohammadnia, Milton G F Fernandes, Jeffery A Hall, Myriam Srour, Roy W R Dudley, Stephanie E J Zandee, Wendy Klement, Alexandre Prat, Hannah E Salapa, Michael C Levin, G R Wayne Moore, Timothy E Kennedy, Christine Vande Velde, Jack P Ante. Regulation of stress granule formation in human oligodendrocytes. Nature communications. vol 15. issue 1. 2024-02-19. PMID:38374028. |
oligodendrocyte (ol) injury and subsequent loss is a pathologic hallmark of multiple sclerosis (ms). |
2024-02-19 |
2024-02-22 |
human |
Jia-Qi Wang, Qiang Li, Jia-Yi He, Fang Zhou, Zi-Hao Huang, Li-Bin Wang, Yuan Zhang, Xing L. Autophagy in Multiple Sclerosis: Phagocytosis and Autophagy of Oligodendrocyte Precursor Cells. Molecular neurobiology. 2024-02-16. PMID:38363533. |
autophagy in multiple sclerosis: phagocytosis and autophagy of oligodendrocyte precursor cells. |
2024-02-16 |
2024-02-18 |
Not clear |
Rocío Benítez-Fernández, Fernando Josa-Prado, Estefanía Sánchez, Yolanda Lao, Alfonso García-Rubia, José Cumella, Ana Martínez, Valle Palomo, Fernando de Castr. Efficacy of a benzothiazole-based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis. CNS neuroscience & therapeutics. vol 30. issue 1. 2024-01-30. PMID:38287523. |
efficacy of a benzothiazole-based lrrk2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis. |
2024-01-30 |
2024-02-01 |
Not clear |
Gina Shim, Alejandra I Romero-Morales, Srinidhi R Sripathy, Brady J Mahe. Utilizing hiPSC-derived oligodendrocytes to study myelin pathophysiology in neuropsychiatric and neurodegenerative disorders. Frontiers in cellular neuroscience. vol 17. 2024-01-26. PMID:38273973. |
oligodendrocyte dysfunction and/or dysmyelination can contribute to a range of neurodegenerative diseases and neuropsychiatric disorders such as multiple sclerosis (ms), leukodystrophy (ld), schizophrenia (scz), and autism spectrum disorder (asd). |
2024-01-26 |
2024-01-28 |
human |
Zhixin Lei, Wensheng Li. Mechanisms Governing Oligodendrocyte Viability in Multiple Sclerosis and Its Animal Models. Cells. vol 13. issue 2. 2024-01-22. PMID:38247808. |
mechanisms governing oligodendrocyte viability in multiple sclerosis and its animal models. |
2024-01-22 |
2024-01-24 |
Not clear |
Omri Zveik, Ariel Rechtman, Livnat Brill, Adi Vaknin-Dembinsk. Anti- and pro-inflammatory milieu differentially regulate differentiation and immune functions of oligodendrocyte progenitor cells. Immunology. 2024-01-20. PMID:38243672. |
oligodendrocyte progenitor cells (opcs) were regarded for years solely for their regenerative role; however, their immune-modulatory roles have gained much attention recently, particularly in the context of multiple sclerosis (ms). |
2024-01-20 |
2024-01-22 |
Not clear |
N L Sheremet, D D Eliseeva, A K Kalashnikova, M N Zakharov. [Typical and atypical optic neuritis]. Vestnik oftalmologii. vol 139. issue 6. 2024-01-18. PMID:38235645. |
demyelinating on can be idiopathic or be one of the symptoms of autoimmune demyelinating diseases of the central nervous system (cns) such as multiple sclerosis (ms), neuromyelitis optica spectrum disorders (nmosd), myelin oligodendrocyte glycoprotein antibody-associated disease (mogad). |
2024-01-18 |
2024-01-20 |
Not clear |
Giordani Rodrigues Dos Passos, Tarso Adoni, Maria Fernanda Mendes, Douglas Kazutoshi Sat. Reshaping neuroimmunology: diagnosis and treatment in the era of precision medicine. Arquivos de neuro-psiquiatria. vol 81. issue 12. 2023-12-29. PMID:38157878. |
this review explores the impact of precision medicine on various neuroimmunological conditions, including multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd), myelin oligodendrocyte glycoprotein antibody-associated disease (mogad), optic neuritis, autoimmune encephalitis, and immune-mediated neuropathies. |
2023-12-29 |
2024-01-05 |
Not clear |
Javier Villacieros-Álvarez, Carmen Espejo, Álvaro Cobo-Calv. Reply to "Myelin Oligodendrocyte Glycoprotein Antibody-Positive Patients Meeting the 2017 McDonald Criteria for Multiple Sclerosis: Challenges in Diagnosis and Treatment Decisions". Annals of neurology. 2023-12-23. PMID:38081749. |
reply to "myelin oligodendrocyte glycoprotein antibody-positive patients meeting the 2017 mcdonald criteria for multiple sclerosis: challenges in diagnosis and treatment decisions". |
2023-12-23 |
2023-12-25 |
Not clear |
Sohyeon Kim, Mi-Yeon Eun, Jae-Joon Lee, Hung Youl Seo. Myelin Oligodendrocyte Glycoprotein Antibody-Positive Patients Meeting the 2017 McDonald Criteria for Multiple Sclerosis: Challenges in Diagnosis and Treatment Decisions. Annals of neurology. 2023-12-21. PMID:38087803. |
myelin oligodendrocyte glycoprotein antibody-positive patients meeting the 2017 mcdonald criteria for multiple sclerosis: challenges in diagnosis and treatment decisions. |
2023-12-21 |
2023-12-23 |
Not clear |
Stephanie B Syc-Mazurek, John J Chen, Pearse Morris, Elia Sechi, Jaywant Mandrekar, Jan-Mendelt Tillema, A Sebastian Lopez-Chiriboga, Claudia Francesca Lucchinetti, Nicholas Zalewski, Laura Cacciaguerra, Marina Buciuc, Karl N Krecke, Steven Anthony Messina, M Tariq Bhatti, Sean J Pittock, Eoin P Flanaga. Frequency of New or Enlarging Lesions on MRI Outside of Clinical Attacks in Patients With MOG-Antibody-Associated Disease. Neurology. vol 99. issue 18. 2023-12-19. PMID:36175150. |
to determine the frequency of new or enlarging t2-hyperintense or enhancing lesions outside of clinical attacks in myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) vs multiple sclerosis (ms) and aquaporin-4 antibody positive neuromyelitis optica spectrum disorder (aqp4+nmosd). |
2023-12-19 |
2023-12-21 |
Not clear |
Patricia A Mathieu, Yim Rodriguez Sampertegui, Fernanda Elias, Alexis Silva Silva, María de Luján Calcagno, Ricardo López, Ana M Adam. Oligodeoxynucleotide IMT504: Effects on Central Nervous System Repair Following Demyelination. Molecular neurobiology. 2023-12-08. PMID:38064102. |
multiple sclerosis (ms) is an immune-mediated central nervous system (cns) disease characterized by demyelination resulting from oligodendrocyte loss and inflammation. |
2023-12-08 |
2023-12-17 |
rat |
Katharina Messias, Renata Moreto, Camila Aquino Cruz, Nathalia Rossoni Ronchi, Antonio Carlos Dos Santos, André Messias, Vanessa Daccach Marque. Clinical spectrum of myelin oligodendrocyte glycoprotein antibody-associated disease in Brazil: a single-center experience. Arquivos de neuro-psiquiatria. vol 81. issue 11. 2023-11-30. PMID:38035583. |
anti-myelin oligodendrocyte glycoprotein (anti-mog) antibody-associated disease (mogad) is an immune-mediated neurological disorder with a broad spectrum of clinical presentation that is often difficult to distinguish from other demyelinating diseases, such as multiple sclerosis and neuromyelitis optica spectrum disorder. |
2023-11-30 |
2023-12-10 |
Not clear |
Danqing Qin, Chunjuan Wang, Dong Li, Shougang Gu. Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway. The Journal of biological chemistry. 2023-11-23. PMID:37995941. |
oligodendrocyte precursor cells (opcs) are present in the adult central nervous system (cns), and their impaired ability to differentiate into myelinating oligodendrocytes (ols) can lead to demyelination in patients with multiple sclerosis (ms), accompanied by neurological deficits and cognitive impairment. |
2023-11-23 |
2023-11-29 |
human |