Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yoav Shulman, Lena Finkelstein, Yakir Levi, Dimitry Kovalchuk, Ayelet Weksler, Alejandro Reichstein, Keren Kigel-Zur, Mazal Davidi, Isaac Levi, Avital Schauder, Keren Rubin, Elhanan Achituv, David Castel, Sigal Meili. A novel sensory wave (P25) in MOG-induced EAE murine model. The journal of pain. 2023-07-31. PMID:37524220. |
myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) is a murine model for multiple sclerosis (ms). |
2023-07-31 |
2023-08-14 |
mouse |
Lara-Jasmin Schröder, Hauke Thiesler, Lina Gretenkort, Thiemo Malte Möllenkamp, Martin Stangel, Viktoria Gudi, Herbert Hildebrand. Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization. Frontiers in cellular neuroscience. vol 17. 2023-07-26. PMID:37492129. |
polysia emerges as a negative regulator of inflammatory microglia and macrophage activation and has been detected on oligodendrocyte precursors and reactive astrocytes in multiple sclerosis lesions. |
2023-07-26 |
2023-08-14 |
Not clear |
Abinaya Ganesan, Pooja Muralidharan, Ramya . The Fulcrum of Demyelination in Multiple Sclerosis. Current protein & peptide science. 2023-07-18. PMID:37461348. |
the four main proteins namely myelin basic protein (mbp), myelin associated oligodendrocyte basic protein (mobp), myelin proteolipid protein (plp) and myelin associated glycoprotein (mag) are known to be critical auto-antigens in causing demyelination in cns leading to ms. three out of these four proteins are intrinsically disordered proteins and in this review, we attempted to understand how these proteins play a crucial role in maintaining the integrity of myelin, by exploring its structural and functional aspects and also their auto-antigenicity leading to multiple sclerosis. |
2023-07-18 |
2023-08-14 |
Not clear |
Grace Gombolay, Jamika Hallman-Coope. COVID-19 and the Pandemic-Related Aspects in Pediatric Demyelinating Disorders. Seminars in pediatric neurology. vol 46. 2023-07-14. PMID:37451752. |
cases of myelin oligodendrocyte glycoprotein antibody disease, neuromyelitis optica spectrum disorder, and multiple sclerosis are also described. |
2023-07-14 |
2023-08-14 |
Not clear |
Christopher J Bridgeman, Shrey A Shah, Robert S Oakes, Christopher M Jewel. Dissecting regulatory T cell expansion using polymer microparticles presenting defined ratios of self-antigen and regulatory cues. Frontiers in bioengineering and biotechnology. vol 11. 2023-07-13. PMID:37441198. |
using rapamycin (rapa) as a modulatory cue and myelin self-peptide (myelin oligodendrocyte glycoprotein- mog) - self-antigen attacked during multiple sclerosis (ms), we integrate these components into polymer particles over a range of ratios and concentrations without altering the physicochemical properties of the particles. |
2023-07-13 |
2023-08-14 |
Not clear |
Pietro Zara, Alessandro Dinoto, Sara Carta, Valentina Floris, Davide Turilli, Adrian Budhram, Sergio Ferrari, Stefania Milia, Paolo Solla, Sara Mariotto, Eoin P Flanagan, A Sebastian Lopez Chiriboga, Elia Sech. Non-demyelinating disorders mimicking and misdiagnosed as NMOSD, a literature review. European journal of neurology. 2023-07-11. PMID:37433584. |
while multiple sclerosis (ms) and myelin oligodendrocyte glycoprotein-igg associated disease (mogad) represent major and well-defined differential diagnoses, non-demyelinating nmosd mimics remain poorly characterized. |
2023-07-11 |
2023-08-14 |
Not clear |
Kimystian L Harrison, Cristina Gaudioso, Victoria A Levasseur, S Richard Dunham, Natalie Schanzer, Connor Keuchel, Amber Salter, Manu S Goyal, Soe Ma. Central Vein Sign in Pediatric Multiple Sclerosis and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. Pediatric neurology. vol 146. 2023-07-05. PMID:37406422. |
central vein sign in pediatric multiple sclerosis and myelin oligodendrocyte glycoprotein antibody-associated disease. |
2023-07-05 |
2023-08-14 |
Not clear |
Kimystian L Harrison, Cristina Gaudioso, Victoria A Levasseur, S Richard Dunham, Natalie Schanzer, Connor Keuchel, Amber Salter, Manu S Goyal, Soe Ma. Central Vein Sign in Pediatric Multiple Sclerosis and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. Pediatric neurology. vol 146. 2023-07-05. PMID:37406422. |
the central vein sign (cvs) on brain magnetic resonance imaging (mri) is a promising diagnostic marker for distinguishing adult multiple sclerosis (ms) from other demyelinating conditions, but its prevalence is not well-established in pediatric-onset multiple sclerosis (poms) versus myelin oligodendrocyte glycoprotein antibody-associated disease (mogad). |
2023-07-05 |
2023-08-14 |
Not clear |
Milton Guilherme Forestieri Fernandes, Abdulshakour Mohammadnia, Florian Pernin, Laura Eleonora Schmitz-Gielsdorf, Caroline Hodgins, Qiao-Ling Cui, Moein Yaqubi, Manon Blain, Jeffery Hall, Roy Dudley, Myriam Srour, Stephanie E J Zandee, Wendy Klement, Alexandre Prat, Jo Anne Stratton, Moses Rodriguez, Tanja Kuhlmann, Wayne Moore, Timothy E Kennedy, Jack P Ante. Mechanisms of metabolic stress induced cell death of human oligodendrocytes: relevance for progressive multiple sclerosis. Acta neuropathologica communications. vol 11. issue 1. 2023-07-05. PMID:37408029. |
oligodendrocyte (ol) injury and loss are central features of evolving lesions in multiple sclerosis. |
2023-07-05 |
2023-08-14 |
human |
Qiao Xu, Xixi Yang, Zhandong Qiu, Dawei Li, Hongxing Wang, Hong Ye, Lidong Jiao, Jing Zhang, Li Di, Peng Lei, Huiqing Dong, Zheng Li. Clinical features of MOGAD with brainstem involvement in the initial attack versus NMOSD and MS. Multiple sclerosis and related disorders. vol 77. 2023-07-04. PMID:37402345. |
clinical features of mogad with brainstem involvement in the initial attack versus nmosd and ms. to assess the characteristics of myelin oligodendrocyte glycoprotein (mog) antibody-associated disorder (mogad) with brainstem involvement in the first event (bsife) and make comparisons with aquaporin-4-igg seropositive neuromyelitis optica spectrum disorder (aqp4-igg-nmosd) and multiple sclerosis (ms). |
2023-07-04 |
2023-08-14 |
Not clear |
Maryam Zoghi, Shapour Jaberzade. A step toward restoring hand functions in patients with multiple sclerosis-a study protocol. Frontiers in rehabilitation sciences. vol 4. 2023-06-30. PMID:37387732. |
multiple sclerosis (ms) is a chronic autoimmune disease characterized by inflammation, demyelination of axons, and oligodendrocyte loss in the central nervous system. |
2023-06-30 |
2023-08-14 |
human |
Jessica Frau, Giancarlo Coghe, Lorena Lorefice, Giuseppe Fenu, Eleonora Cocc. The Role of Microorganisms in the Etiopathogenesis of Demyelinating Diseases. Life (Basel, Switzerland). vol 13. issue 6. 2023-06-28. PMID:37374092. |
multiple sclerosis (ms), neuromyelitis optica (nmo) and myelin oligodendrocyte glycoprotein antibody disease (mogad) are inflammatory diseases of the central nervous system (cns) with a multifactorial aetiology. |
2023-06-28 |
2023-08-14 |
human |
Edgar Carnero Contentti, Darin T Okuda, Juan I Rojas, Claudia Chien, Friedemman Paul, Ricardo Alons. MRI to differentiate multiple sclerosis, neuromyelitis optica, and myelin oligodendrocyte glycoprotein antibody disease. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2023-06-15. PMID:37322542. |
differentiating multiple sclerosis (ms) from other relapsing inflammatory autoimmune diseases of the central nervous system such as neuromyelitis optica spectrum disorder (nmosd) and myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) is crucial in clinical practice. |
2023-06-15 |
2023-08-14 |
Not clear |
Marc Dinkin, Swetha Sath. Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19. Seminars in neurology. 2023-06-13. PMID:37311536. |
optic neuritis has frequently been reported, sometimes along with acute disseminated encephalomyelopathy, often in association with either myelin oligodendrocyte glycoprotein antibodies (mog-igg) or less commonly aquaporin-4 seropositivity or in newly diagnosed multiple sclerosis. |
2023-06-13 |
2023-08-14 |
Not clear |
Hans Lassman. Top ten discoveries of the year: Neuroinflammation. Free neuropathology. vol 1. 2023-06-07. PMID:37283667. |
they include topics related to new mechanisms of inflammation and immune mediated neurodegeneration, which are relevant for multiple sclerosis (publications 1 to 4) and discuss the role of specific autoantibodies against myelin oligodendrocyte glycoprotein or aquaporin 4 in neuromyelitis optica spectrum disorders (publications 5 and 6). |
2023-06-07 |
2023-08-14 |
Not clear |
Assia Tiane, Melissa Schepers, Rick A Reijnders, Lieve van Veggel, Sarah Chenine, Ben Rombaut, Emma Dempster, Catherine Verfaillie, Kobi Wasner, Anne Grünewald, Jos Prickaerts, Ehsan Pishva, Niels Hellings, Daniel van den Hove, Tim Vanmierl. From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions. Acta neuropathologica. 2023-06-07. PMID:37286732. |
in the progressive phase of multiple sclerosis (ms), the hampered differentiation capacity of oligodendrocyte precursor cells (opcs) eventually results in remyelination failure. |
2023-06-07 |
2023-08-14 |
Not clear |
Yu Xie, Chaolei Jin, Hongzhen Sang, Wenhua Liu, Junpeng Wan. Ivermectin Protects Against Experimental Autoimmune Encephalomyelitis in Mice by Modulating the Th17/Treg Balance Involved in the IL-2/STAT5 Pathway. Inflammation. 2023-05-25. PMID:37227550. |
multiple sclerosis (ms), a t-cell-mediated autoimmune disease that affects the central nervous system (cns), is characterized by white matter demyelination, axon destruction, and oligodendrocyte degeneration. |
2023-05-25 |
2023-08-14 |
mouse |
Vyanka Redenbaugh, Nicholas H Chia, Laura Cacciaguerra, Jennifer A McCombe, Jan-Mendelt Tillema, John J Chen, A Sebastian Lopez Chiriboga, Elia Sechi, Yael Hacohen, Sean J Pittock, Eoin P Flanaga. Comparison of MRI T2-lesion evolution in pediatric MOGAD, NMOSD, and MS. Multiple sclerosis (Houndmills, Basingstoke, England). 2023-05-23. PMID:37218499. |
magnetic resonance imaging (mri) t2-lesions resolve more often in myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) than aquaporin-4 igg-positive neuromyelitis optica spectrum disorder (aqp4 + nmosd) and multiple sclerosis (ms) in adults but few studies analyzed children. |
2023-05-23 |
2023-08-14 |
Not clear |
Yanan Chen, Songhua Quan, Vaibhav Patil, Rejani B Kunjamma, Haley M Tokars, Eric D Leisten, Godwin Joy, Samantha Wills, Jonah R Chan, Yvette C Wong, Brian Popk. Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response. Glia. 2023-05-19. PMID:37203250. |
ifn-γ, which is a critical inflammatory cytokine in multiple sclerosis (ms), inhibits oligodendrocyte precursor cell (opc) differentiation in culture and triggers a mild isr. |
2023-05-19 |
2023-08-14 |
mouse |
Brian Florenzo, J Nicholas Brento. Socioeconomic, Clinical, and Laboratory Parameters Differentiating Pediatric Patients With MOG Antibody-Associated Disease and Multiple Sclerosis. Journal of child neurology. 2023-05-01. PMID:37122175. |
studies indicate differences in the clinical phenotypes and neuroimaging of children with myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) compared to multiple sclerosis; however, there are limited data assessing the socioeconomic and paraclinical differences between these distinct disorders. |
2023-05-01 |
2023-08-14 |
human |