| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sharon W Way, Joseph R Podojil, Benjamin L Clayton, Anita Zaremba, Tassie L Collins, Rejani B Kunjamma, Andrew P Robinson, Pedro Brugarolas, Robert H Miller, Stephen D Miller, Brian Popk. Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic. Nature communications. vol 6. 2015-08-14. PMID:25766071. |
oligodendrocyte death contributes to the pathogenesis of the inflammatory demyelinating disease multiple sclerosis (ms). |
2015-08-14 |
2023-08-13 |
mouse |
| Shabnam Nadjafi, Soltan-Ahmad Ebrahimi, Nahid Rahbar-Roshande. Effect of berberine on nitric oxide production during oxygen-glucose deprivation/reperfusion in OLN-93 oligodendrocytes. Pakistan journal of biological sciences : PJBS. vol 17. issue 11. 2015-07-30. PMID:26027164. |
the overactivation of ionotropic glutamate receptors which is known as the excitotoxicity, is an important phenomenon because of the contribution in acute injury to the central nervous system, chronic neurodegenerative disorders, oligodendrocyte loss and demyelinating diseases as multiple sclerosis (ms). |
2015-07-30 |
2023-08-13 |
rat |
| Tan Wang, Na-na Xi, Yu Chen, Xiao-feng Shang, Qiang Hu, Jiang-fan Chen, Rong-yuan Zhen. Chronic caffeine treatment protects against experimental autoimmune encephalomyelitis in mice: therapeutic window and receptor subtype mechanism. Neuropharmacology. vol 86. 2015-07-14. PMID:25019206. |
chronic treatment with caffeine, the most widely consumed psychoactive drug and a non-selective antagonist of adenosine receptors, can protection against myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), an animal model of multiple sclerosis (ms). |
2015-07-14 |
2023-08-13 |
mouse |
| Aurélia Sahel, Fernando C Ortiz, Christophe Kerninon, Paloma P Maldonado, María Cecilia Angulo, Brahim Nait-Oumesma. Alteration of synaptic connectivity of oligodendrocyte precursor cells following demyelination. Frontiers in cellular neuroscience. vol 9. 2015-04-08. PMID:25852473. |
oligodendrocyte precursor cells (opcs) are a major source of remyelinating oligodendrocytes in demyelinating diseases such as multiple sclerosis (ms). |
2015-04-08 |
2023-08-13 |
mouse |
| Enrique Garea Rodriguez, Christiane Wegner, Mario Kreutzfeldt, Katharina Neid, Dietmar R Thal, Tanja Jürgens, Wolfgang Brück, Christine Stadelmann, Doron Merkle. Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination. Acta neuropathologica. vol 128. issue 2. 2015-02-26. PMID:24563023. |
oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination. |
2015-02-26 |
2023-08-12 |
rat |
| Oliver Findling, Isabelle Durot, Anja Weck, Simon Jung, Christian P Kamm, Isabell Greeve, Heinrich P Mattle, Johann Sellne. Antimyelin antibodies as predictors of disability after clinically isolated syndrome. The International journal of neuroscience. vol 124. issue 8. 2015-02-23. PMID:24274327. |
there is controversy whether determination of antibodies against myelin, myelin oligodendrocyte glycoprotein, and myelin basic protein in serum from patients with a first episode suggestive of multiple sclerosis is of prognostic value. |
2015-02-23 |
2023-08-12 |
Not clear |
| Vanja Tepavčević, Christophe Kerninon, Marie Stéphane Aigrot, Elodie Meppiel, Sabah Mozafari, Raphaelle Arnould-Laurent, Philippe Ravassard, Timothy E Kennedy, Brahim Nait-Oumesmar, Catherine Lubetzk. Early netrin-1 expression impairs central nervous system remyelination. Annals of neurology. vol 76. issue 2. 2015-02-09. PMID:24942777. |
chronically demyelinated multiple sclerosis (ms) lesions are frequently characterized by scarce undifferentiated oligodendrocyte progenitor cells (opcs), suggesting the exhaustion of a local opc pool followed by failure of recruitment and differentiation. |
2015-02-09 |
2023-08-13 |
Not clear |
| Soo Yuen Leong, Vijayaraghava T S Rao, Jenea M Bin, Pavel Gris, Mugundhine Sangaralingam, Timothy E Kennedy, Jack P Ante. Heterogeneity of oligodendrocyte progenitor cells in adult human brain. Annals of clinical and translational neurology. vol 1. issue 4. 2015-01-15. PMID:25590039. |
remyelination in multiple sclerosis has been attributed to the presence of oligodendrocyte progenitor cells (opcs) in brain parenchyma. |
2015-01-15 |
2023-08-13 |
human |
| Maria Galuppo, Sabrina Giacoppo, Gina Rosalinda De Nicola, Renato Iori, Michele Navarra, Giovanni Enrico Lombardo, Placido Bramanti, Emanuela Mazzo. Antiinflammatory activity of glucomoringin isothiocyanate in a mouse model of experimental autoimmune encephalomyelitis. Fitoterapia. vol 95. 2015-01-07. PMID:24685508. |
for this reason, c57bl/6 male mice were injected with myelin oligodendrocyte glycoprotein35-55 which is able to evoke an autoimmune response against myelin fibers miming human multiple sclerosis physiopatogenesis. |
2015-01-07 |
2023-08-12 |
mouse |
| Kyriaki Markoullis, Irene Sargiannidou, Natasa Schiza, Federico Roncaroli, Richard Reynolds, Kleopas A Kleop. Oligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter. Journal of neuropathology and experimental neurology. vol 73. issue 9. 2014-12-17. PMID:25101702. |
oligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter. |
2014-12-17 |
2023-08-13 |
Not clear |
| Francesco Fazio, Cristina Zappulla, Serena Notartomaso, Carla Busceti, Alban Bessede, Pamela Scarselli, Carmine Vacca, Marco Gargaro, Claudia Volpi, Massimo Allegrucci, Luana Lionetto, Maurizio Simmaco, Maria Laura Belladonna, Ferdinando Nicoletti, Francesca Fallarin. Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice. Neuropharmacology. vol 81. 2014-12-15. PMID:24565643. |
was highly protective against experimental autoimmune encephalomyelitis (eae) induced by the myelin oligodendrocyte glycoprotein (mog35-55) peptide, which models multiple sclerosis in mice. |
2014-12-15 |
2023-08-12 |
mouse |
| Elmira Mikaeili Agah, Kazem Parivar, Mohammad Taghi Joghatae. Therapeutic effect of transplanted human Wharton's jelly stem cell-derived oligodendrocyte progenitor cells (hWJ-MSC-derived OPCs) in an animal model of multiple sclerosis. Molecular neurobiology. vol 49. issue 2. 2014-11-21. PMID:23982748. |
therapeutic effect of transplanted human wharton's jelly stem cell-derived oligodendrocyte progenitor cells (hwj-msc-derived opcs) in an animal model of multiple sclerosis. |
2014-11-21 |
2023-08-12 |
mouse |
| Monica Moreno, Fuzheng Guo, Emily Mills Ko, Peter Bannerman, Athena Soulika, David Pleasur. Origins and significance of astrogliosis in the multiple sclerosis model, MOG peptide EAE. Journal of the neurological sciences. vol 333. issue 1-2. 2014-11-06. PMID:23294494. |
experimental autoimmune encephalomyelitis elicited in mice by immunization with myelin oligodendrocyte glycoprotein peptide 35-55 provides a means by which to explore the genesis and disease significance of astrogliosis during a chronic immune-mediated cns inflammatory/demyelinative disorder that, in its' pathological features, strongly resembles multiple sclerosis. |
2014-11-06 |
2023-08-12 |
mouse |
| Joyce A Benjamin. Direct effects of secretory products of immune cells on neurons and glia. Journal of the neurological sciences. vol 333. issue 1-2. 2014-11-06. PMID:23827826. |
to explore the hypothesis that b cells of patients with multiple sclerosis secrete soluble products damaging to oligodendroglia (ol), in collaboration with dr. bar-or at montreal neurologic institute, we compared secretory products of cultured b cells from relapsing remitting multiple sclerosis (rrms) patients and healthy controls. |
2014-11-06 |
2023-08-12 |
rat |
| Aparna Shetty, Sheena G Gupta, Michel Varrin-Doyer, Martin S Weber, Thomas Prod'homme, Nicolas Molnarfi, Niannian Ji, Patricia A Nelson, Juan C Patarroyo, Ulf Schulze-Topphoff, Stephen E Fogal, Thomas Forsthuber, Raymond A Sobel, Claude C A Bernard, Anthony J Slavin, Scott S Zamvi. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE. Neurology(R) neuroimmunology & neuroinflammation. vol 1. issue 2. 2014-10-23. PMID:25340074. |
studies evaluating t-cell recognition of myelin oligodendrocyte glycoprotein (mog) in multiple sclerosis (ms) and its model, experimental autoimmune encephalomyelitis (eae), have focused mostly on its 117 amino acid (aa) extracellular domain, especially peptide (p) 35-55. |
2014-10-23 |
2023-08-13 |
Not clear |
| Ana Martins da Silva, Maria Ernestina Santo. JCV epidemiology in MS (JEMS)--epidemiology of anti-JCV antibody prevalence in multiple sclerosis patients--Portuguese data. Journal of the neurological sciences. vol 337. issue 1-2. 2014-10-06. PMID:24369270. |
progressive multifocal leukoencephalopathy, caused by oligodendrocyte lytic infection by jcvirus, is a growing concern for patients undergoing immune modulatory therapies for treatment of autoimmune diseases, such as multiple sclerosis (ms). |
2014-10-06 |
2023-08-12 |
Not clear |
| J J García-Vallejo, J M Ilarregui, H Kalay, S Chamorro, N Koning, W W Unger, M Ambrosini, V Montserrat, R J Fernandes, S C M Bruijns, J R T van Weering, N J Paauw, T O'Toole, J van Horssen, P van der Valk, K Nazmi, J G M Bolscher, J Bajramovic, C D Dijkstra, B A 't Hart, Y van Kooy. CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG. The Journal of experimental medicine. vol 211. issue 7. 2014-09-04. PMID:24935259. |
myelin oligodendrocyte glycoprotein (mog), a constituent of central nervous system myelin, is an important autoantigen in the neuroinflammatory disease multiple sclerosis (ms). |
2014-09-04 |
2023-08-13 |
human |
| De-Hyung Lee, Ralf A Linke. The role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? Expert opinion on therapeutic targets. vol 16. issue 5. 2014-08-29. PMID:22494461. |
the role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? |
2014-08-29 |
2023-08-12 |
Not clear |
| Jong-Hwan Lee, Hyuk Seong Seo, Jong Am Song, Koo Chul Kwon, Eun Jung Lee, Ho Jin Kim, Eun Bong Lee, Young Joo Cha, Jeewon Le. Proteinticle engineering for accurate 3D diagnosis. ACS nano. vol 7. issue 12. 2014-08-26. PMID:24195532. |
the surface display of the extracellular domain of myelin oligodendrocyte glycoprotein (mog) with native conformation successfully discriminated between autoantibodies to native or denatured mog, leading to the reliable diagnosis of multiple sclerosis with enhanced accuracy. |
2014-08-26 |
2023-08-12 |
human |
| Yiqiao Li, Yanyan Zhang, Weiwei Han, Fengyin Hu, Yu'e Qian, Qiang Che. TRO19622 promotes myelin repair in a rat model of demyelination. The International journal of neuroscience. vol 123. issue 11. 2014-05-19. PMID:23668883. |
multiple sclerosis is a neurodegenerative autoimmune disease characterized by diffuse oligodendrocyte injury, axonal loss and multifocal demyelination of myelin sheaths in the central nervous system. |
2014-05-19 |
2023-08-12 |
rat |