| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eve E Kelland, Wendy Gilmore, Leslie P Weiner, Brett T Lun. The dual role of CXCL8 in human CNS stem cell function: multipotent neural stem cell death and oligodendrocyte progenitor cell chemotaxis. Glia. vol 59. issue 12. 2013-07-08. PMID:22407782. |
research into multiple sclerosis (ms) has shown that cells purportedly important to myelin repair within the cns, namely neural stem cells (nsc) and oligodendrocyte progenitor cells (opc), are recruited to active lesion sites during the course of the disease. |
2013-07-08 |
2023-08-12 |
human |
| Jing-Hua Piao, Yanping Wang, Ian D Dunca. CD44 is required for the migration of transplanted oligodendrocyte progenitor cells to focal inflammatory demyelinating lesions in the spinal cord. Glia. vol 61. issue 3. 2013-07-03. PMID:23280959. |
remyelination of chronically demyelinated axons in multiple sclerosis (ms) requires the recruitment of endogenous cells or their replacement by transplanted, exogenous oligodendrocyte progenitor cells (opcs). |
2013-07-03 |
2023-08-12 |
rat |
| Carrie Tatar, Denise Bessert, Harley Tse, Robert P Skof. Determinants of central nervous system adult neurogenesis are sex, hormones, mouse strain, age, and brain region. Glia. vol 61. issue 2. 2013-05-30. PMID:23027402. |
multiple sclerosis is a sexually dimorphic (sd) disease that causes oligodendrocyte death, but sd of glial cells is poorly studied. |
2013-05-30 |
2023-08-12 |
mouse |
| Tracy J Yuen, Kory R Johnson, Veronique E Miron, Chao Zhao, Jacqueline Quandt, Marie C Harrisingh, Matthew Swire, Anna Williams, Henry F McFarland, Robin J M Franklin, Charles Ffrench-Constan. Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. Brain : a journal of neurology. vol 136. issue Pt 4. 2013-05-30. PMID:23518706. |
in studies to identify the receptor responsible for this regenerative effect of endothelin 2, analysis of both remyelination following experimental demyelination and of different stages of multiple sclerosis lesions in human post-mortem tissue revealed high levels of endothelin receptor type b in oligodendrocyte lineage cells. |
2013-05-30 |
2023-08-12 |
human |
| Wensheng Lin, Yifeng Lin, Jin Li, Ali G Fenstermaker, Sharon W Way, Benjamin Clayton, Stephanie Jamison, Heather P Harding, David Ron, Brian Popk. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 14. 2013-05-28. PMID:23554479. |
there is compelling evidence that oligodendrocyte apoptosis, in response to cns inflammation, contributes significantly to the development of the demyelinating disorder multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (eae). |
2013-05-28 |
2023-08-12 |
mouse |
| François Curtin, Alois B Lang, Hervé Perron, Marion Laumonier, Virginie Vidal, Hervé C Porchet, Hans-Peter Hartun. GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study. Clinical therapeutics. vol 34. issue 12. 2013-05-17. PMID:23200102. |
due to its proinflammatory property and an inhibitory effect on oligodendrocyte precursor cell differentiation, the msrv-env protein could play a crucial role in the pathogeny of multiple sclerosis. |
2013-05-17 |
2023-08-12 |
human |
| Josephine M J Stoffels, Jenny C de Jonge, Mirjana Stancic, Anita Nomden, Miriam E van Strien, Dan Ma, Zuzana Sisková, Olaf Maier, Charles Ffrench-Constant, Robin J M Franklin, Dick Hoekstra, Chao Zhao, Wia Baro. Fibronectin aggregation in multiple sclerosis lesions impairs remyelination. Brain : a journal of neurology. vol 136. issue Pt 1. 2013-04-23. PMID:23365094. |
most intriguingly, injection of astrocyte-derived fibronectin aggregates in toxin-induced demyelinated lesions inhibited oligodendrocyte differentiation and remyelination, and fibronectin aggregates are barely expressed in remyelinated multiple sclerosis lesions. |
2013-04-23 |
2023-08-12 |
Not clear |
| Fanny Schmidt, Monique van den Eijnden, Rosanna Pescini Gobert, Gabriela P Saborio, Susanna Carboni, Chantal Alliod, Sandrine Pouly, Susan M Staugaitis, Ranjan Dutta, Bruce Trapp, Rob Hooft van Huijsduijne. Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach. PloS one. vol 7. issue 7. 2013-04-02. PMID:22792334. |
multiple sclerosis (ms) is a neuroinflammatory disease characterized by a progressive loss of myelin and a failure of oligodendrocyte (ol)-mediated remyelination, particularly in the progressive phases of the disease. |
2013-04-02 |
2023-08-12 |
Not clear |
| Yan Xu, Yao Zhang, Cai-yan Liu, Bin Peng, Jian-ming Wang, Xiao-jun Zhang, Hai-feng Li, Li-ying Cu. Serum antibodies to 25 myelin oligodendrocyte glycoprotein epitopes in multiple sclerosis and neuromyelitis optica: clinical value for diagnosis and disease activity. Chinese medical journal. vol 125. issue 18. 2013-02-13. PMID:22964310. |
serum antibodies to 25 myelin oligodendrocyte glycoprotein epitopes in multiple sclerosis and neuromyelitis optica: clinical value for diagnosis and disease activity. |
2013-02-13 |
2023-08-12 |
Not clear |
| Yan Xu, Yao Zhang, Cai-yan Liu, Bin Peng, Jian-ming Wang, Xiao-jun Zhang, Hai-feng Li, Li-ying Cu. Serum antibodies to 25 myelin oligodendrocyte glycoprotein epitopes in multiple sclerosis and neuromyelitis optica: clinical value for diagnosis and disease activity. Chinese medical journal. vol 125. issue 18. 2013-02-13. PMID:22964310. |
whether antibody to myelin oligodendrocyte glycoprotein (mog) can be a diagnostic marker for multiple sclerosis (ms) is still controversial. |
2013-02-13 |
2023-08-12 |
Not clear |
| Stefan Bittner, Marcella A Bauer, Petra Ehling, Nicole Bobak, Johanna Breuer, Alexander M Herrmann, Melina Golfels, Heinz Wiendl, Thomas Budde, Sven G Meut. The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis. Experimental neurology. vol 238. issue 2. 2013-01-21. PMID:22960185. |
previously, it was shown that t lymphocytes obtained from task1(-/-) mice display impaired t cell effector functions and that task1(-/-) mice show a significantly reduced disease severity in myelin oligodendrocyte glycoprotein (mog(35-55)) peptide induced experimental autoimmune encephalomyelitis (eae), an animal model of multiple sclerosis. |
2013-01-21 |
2023-08-12 |
mouse |
| Marie Cathrin Mayer, Edgar Mein. Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more. Therapeutic advances in neurological disorders. vol 5. issue 3. 2013-01-10. PMID:22590479. |
one candidate autoantigen for multiple sclerosis (ms) is myelin oligodendrocyte glycoprotein (mog). |
2013-01-10 |
2023-08-12 |
Not clear |
| Sima Jafarirad, Fereydoon Siassi, Mohammad-Hossein Harirchian, Mohammad-Ali Sahraian, Mohammad-Reza Eshraghian, Fazel Shokri, Reza Amani, Sama Bitarafan, Sabah Mozafari, Aliakbar Saboor-Yaragh. The effect of vitamin A supplementation on stimulated T-cell proliferation with myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. Journal of neurosciences in rural practice. vol 3. issue 3. 2012-11-29. PMID:23188981. |
the effect of vitamin a supplementation on stimulated t-cell proliferation with myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. |
2012-11-29 |
2023-08-12 |
Not clear |
| Markus Kipp, Marion Victor, Gianvito Martino, Robin J M Frankli. Endogeneous remyelination: findings in human studies. CNS & neurological disorders drug targets. vol 11. issue 5. 2012-11-19. PMID:22583436. |
specifically mentioned will be the distribution of oligodendrocyte progenitor cells in demyelinated multiple sclerosis plaques and therapeutic approaches which aim to boost intrinsic properties of progenitor cells or to supply progenitors by cell transplantation approaches. |
2012-11-19 |
2023-08-12 |
human |
| Péter Acs, Sámuel Komol. Selective ultrastructural vulnerability in the cuprizone-induced experimental demyelination. Ideggyogyaszati szemle. vol 65. issue 7-8. 2012-11-13. PMID:23074847. |
it has been reported that multiple sclerosis has four different neuropathological subtypes, and two of them (type iii and iv) are characterized by primary oligodendrocyte loss. |
2012-11-13 |
2023-08-12 |
mouse |
| Takeshi Kezuka, Yoshihiko Usui, Naoyuki Yamakawa, Yoshimichi Matsunaga, Ryusaku Matsuda, Masayuki Masuda, Hiroya Utsumi, Keiko Tanaka, Hiroshi Got. Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. vol 32. issue 2. 2012-11-06. PMID:22157536. |
myelin oligodendrocyte glycoprotein (mog) is well known as the causative protein of multiple sclerosis (ms). |
2012-11-06 |
2023-08-12 |
Not clear |
| S Hochmeister, M Romauch, J Bauer, T Seifert-Held, R Weissert, C Linington, H P Hartung, F Fazekas, M K Storc. Re-expression of N-cadherin in remyelinating lesions of experimental inflammatory demyelination. Experimental neurology. vol 237. issue 1. 2012-11-05. PMID:22735489. |
the aim of our study was to investigate the expression pattern of n-cadherin immunoreactivity in experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein (mog-eae), an animal model closely mimicking multiple sclerosis. |
2012-11-05 |
2023-08-12 |
Not clear |
| Xing-Shu Chen, Xing-Hua Chen, Jian-Ning Ye, Qi-Yan Cai, Xiao-Li Zhan, Zhi Liu, Zhong-Xiang Ya. Developmental changes and subcellular location in inhibitor of DNA binding 2 (Id2) immunoreactivity in the rat Corpus callosum. Acta histochemica. vol 114. issue 7. 2012-10-31. PMID:22172709. |
the mechanisms underlying oligodendrocyte differentiation and myelination are still unclear, but understanding them will be critical for the development of therapies for multiple sclerosis. |
2012-10-31 |
2023-08-12 |
rat |
| John W Prineas, John D E Parrat. Oligodendrocytes and the early multiple sclerosis lesion. Annals of neurology. vol 72. issue 1. 2012-10-24. PMID:22829266. |
there is little agreement among neuropathologists regarding the timing and nature of oligodendrocyte loss in multiple sclerosis (ms). |
2012-10-24 |
2023-08-12 |
Not clear |
| Janusz J Jadasz, Ludwig Aigner, Francisco J Rivera, Patrick Kür. The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis. Cell and tissue research. vol 349. issue 1. 2012-10-10. PMID:22322424. |
multiple sclerosis (ms) is an autoimmune disease that leads to oligodendrocyte loss and subsequent demyelination of the adult central nervous system (cns). |
2012-10-10 |
2023-08-12 |
human |