| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neil Saigal, Alisha K Bajwa, Sara S Faheem, Robert A Coleman, Suresh K Pandey, Cristian C Constantinescu, Vanessa Fong, Jogeshwar Mukherje. Evaluation of serotonin 5-HT(1A) receptors in rodent models using [¹⁸F]mefway PET. Synapse (New York, N.Y.). vol 67. issue 9. 2014-02-13. PMID:23504990. |
serotonin 5-ht(1a) receptors have been investigated in various cns disorders, including epilepsy, mood disorders, and neurodegeneration. |
2014-02-13 |
2023-08-12 |
mouse |
| Francesca Calabrese, Gianluigi Guidotti, Anthonieke Middelman, Giorgio Racagni, Judith Homberg, Marco A Riv. Lack of serotonin transporter alters BDNF expression in the rat brain during early postnatal development. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23564488. |
these early changes may increase stress susceptibility during critical windows of brain maturation, which may eventually lead to the heightened predisposition to mood disorders found in individual carrying genetic variants of the serotonin transporter. |
2014-02-12 |
2023-08-12 |
rat |
| Mark J Niciu, Dawn F Ionescu, Daniel C Mathews, Erica M Richards, Carlos A Zarat. Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part I: major depressive disorder. CNS spectrums. vol 18. issue 5. 2014-01-23. PMID:23462230. |
the etiopathogenesis and treatment of major mood disorders have historically focused on modulation of monoaminergic (serotonin, norepinephrine, dopamine) and amino acid [γ-aminobutyric acid (gaba), glutamate] receptors at the plasma membrane. |
2014-01-23 |
2023-08-12 |
Not clear |
| Vibe Gedsoe Frokjaer, David Erritzoe, Klaus Kähler Holst, Peter Steen Jensen, Peter Mondrup Rasmussen, Patrick Macdonald Fisher, William Baaré, Kathrine Skak Madsen, Jacob Madsen, Claus Svarer, Gitte Moos Knudse. Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 4. 2014-01-06. PMID:22732516. |
individuals carrying the low-expressing variants (s and lg) of the 5-httlpr promoter polymorphism of the serotonin transporter (sert) gene are at higher risk for developing mood disorders when exposed to severe stress and display higher cortisol responses when exposed to psychosocial stressors relative to high expressing 5-httlpr variants. |
2014-01-06 |
2023-08-12 |
Not clear |
| Cristina Stasi, Massimo Rosselli, Anna Linda Zignego, Giacomo Laffi, Stefano Milan. Serotonin and its implication in the side-effects of interferon-based treatment of patients with chronic viral hepatitis: Pharmacological interventions. Hepatology research : the official journal of the Japan Society of Hepatology. vol 44. issue 1. 2014-01-06. PMID:23607322. |
serotonin reuptake inhibitors significantly improve mood disorders, but the use of these drugs requires caution because some studies reported the emergence of mania in patients treated for depression during antiviral therapy. |
2014-01-06 |
2023-08-12 |
Not clear |
| J John Man. The serotonergic system in mood disorders and suicidal behaviour. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 368. issue 1615. 2013-09-12. PMID:23440471. |
the same neural circuitry and serotonin deficiency may contribute to impulsive aggressive traits that are part of the diathesis for suicidal behaviour and are associated with early onset mood disorders and greater risk for suicidal behaviour. |
2013-09-12 |
2023-08-12 |
Not clear |
| Taro Kishi, Reiji Yoshimura, Yasuhisa Fukuo, Tomo Okochi, Shinji Matsunaga, Wakako Umene-Nakano, Jun Nakamura, Alessandro Serretti, Christoph U Correll, John M Kane, Nakao Iwat. The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder. European archives of psychiatry and clinical neuroscience. vol 263. issue 2. 2013-08-19. PMID:22752684. |
the serotonin 1a receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder. |
2013-08-19 |
2023-08-12 |
Not clear |
| Taro Kishi, Reiji Yoshimura, Yasuhisa Fukuo, Tomo Okochi, Shinji Matsunaga, Wakako Umene-Nakano, Jun Nakamura, Alessandro Serretti, Christoph U Correll, John M Kane, Nakao Iwat. The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder. European archives of psychiatry and clinical neuroscience. vol 263. issue 2. 2013-08-19. PMID:22752684. |
the serotonin 1a receptor gene (htr1a) has been associated with mood disorders (mds), including major depressive disorder (mdd) and bipolar disorder (bp). |
2013-08-19 |
2023-08-12 |
Not clear |
| Taro Kishi, Hiroshi Ichinose, Reiji Yoshimura, Yasuhisa Fukuo, Tsuyoshi Kitajima, Toshiya Inada, Hiroshi Kunugi, Tadafumi Kato, Takeo Yoshikawa, Hiroshi Ujike, Giovanna M Musso, Wakako Umene-Nakano, Jun Nakamura, Norio Ozaki, Nakao Iwat. GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder. Journal of affective disorders. vol 142. issue 1-3. 2013-08-13. PMID:22770721. |
tetrahydrobiopterin (bh4) plays an important role in the biosynthesis of serotonin, melatonin and catecholamines, all of which are implicated in the pathophysiology of mood disorders (mds), including major depressive disorder (mdd) and bipolar disorder (bp). |
2013-08-13 |
2023-08-12 |
Not clear |
| José Julio Rodríguez, Harun N Noristani, Alexei Verkhratsk. The serotonergic system in ageing and Alzheimer's disease. Progress in neurobiology. vol 99. issue 1. 2013-07-10. PMID:22766041. |
abnormal 5-ht neurotransmission contributes to the deterioration of cognitive processes in ageing, ad and other neuropathologies, including schizophrenia, stress, mood disorders and depression. |
2013-07-10 |
2023-08-12 |
Not clear |
| Nicole L Baganz, Randy D Blakel. A dialogue between the immune system and brain, spoken in the language of serotonin. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336044. |
in the cns, the contributions of 5-ht modulate a broad range of targets, most notably, hypothalamic, limbic and cortical circuits linked to the control of mood and mood disorders. |
2013-07-02 |
2023-08-12 |
Not clear |
| Alice B Loughridge, Benjamin N Greenwood, Heidi E W Day, Matthew B McQueen, Monika Fleshne. Microarray analyses reveal novel targets of exercise-induced stress resistance in the dorsal raphe nucleus. Frontiers in behavioral neuroscience. vol 7. 2013-05-30. PMID:23717271. |
serotonin (5-ht) is implicated in the development of stress-related mood disorders in humans. |
2013-05-30 |
2023-08-12 |
human |
| Alice B Loughridge, Benjamin N Greenwood, Heidi E W Day, Matthew B McQueen, Monika Fleshne. Microarray analyses reveal novel targets of exercise-induced stress resistance in the dorsal raphe nucleus. Frontiers in behavioral neuroscience. vol 7. 2013-05-30. PMID:23717271. |
the drn has a high concentration of 5-ht neurons and is implicated in stress-related mood disorders. |
2013-05-30 |
2023-08-12 |
human |
| Shruti Kant, Erica Liebel. Recognizing serotonin toxicity in the pediatric emergency department. Pediatric emergency care. vol 28. issue 8. 2013-05-21. PMID:22863827. |
the use of selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors in treating depression, mood disorders, and behavioral disorders has escalated dramatically in the last 20 years, resulting in increased risk and clinical presentation of serotonin toxicity. |
2013-05-21 |
2023-08-12 |
Not clear |
| Maddalena D Caiati, Enrico Cherubin. Fluoxetine impairs GABAergic signaling in hippocampal slices from neonatal rats. Frontiers in cellular neuroscience. vol 7. 2013-05-06. PMID:23641199. |
fluoxetine (prozac), an antidepressant known to selectively inhibit serotonin reuptake, is widely used to treat mood disorders in women suffering from depression during pregnancy and postpartum period. |
2013-05-06 |
2023-08-12 |
human |
| Michael Kometer, André Schmidt, Rosilla Bachmann, Erich Studerus, Erich Seifritz, Franz X Vollenweide. Psilocybin biases facial recognition, goal-directed behavior, and mood state toward positive relative to negative emotions through different serotonergic subreceptors. Biological psychiatry. vol 72. issue 11. 2013-04-23. PMID:22578254. |
serotonin (5-ht) 1a and 2a receptors have been associated with dysfunctional emotional processing biases in mood disorders. |
2013-04-23 |
2023-08-12 |
Not clear |
| H Sugawara, K Iwamoto, M Bundo, J Ueda, T Miyauchi, A Komori, A Kazuno, N Adati, I Kusumi, Y Okazaki, J Ishigooka, T Kojima, T Kat. Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins. Translational psychiatry. vol 1. 2013-04-04. PMID:22832526. |
serotonin transporter (htt) is a target of antidepressants and is one of the strongest candidate molecules of mood disorder, however, genetic study showed equivocal results. |
2013-04-04 |
2023-08-12 |
Not clear |
| Carlotta Belaise, Alessia Gatti, Virginie-Anne Chouinard, Guy Chouinar. Patient online report of selective serotonin reuptake inhibitor-induced persistent postwithdrawal anxiety and mood disorders. Psychotherapy and psychosomatics. vol 81. issue 6. 2013-03-21. PMID:22964821. |
patient online report of selective serotonin reuptake inhibitor-induced persistent postwithdrawal anxiety and mood disorders. |
2013-03-21 |
2023-08-12 |
Not clear |
| Jade M Franklin, Gonzalo A Carrasc. Cannabinoid-induced enhanced interaction and protein levels of serotonin 5-HT(2A) and dopamine D₂ receptors in rat prefrontal cortex. Journal of psychopharmacology (Oxford, England). vol 26. issue 10. 2013-01-30. PMID:22791651. |
we hypothesize that the enhanced cannabinoid-induced interaction between 5-ht(2a) and d₂ receptors and in 5-ht(2a) and d₂ receptors protein levels in the pfcx might provide a molecular mechanism by which activation of cannabinoid receptors might be contribute to the pathophysiology of some cognitive and mood disorders. |
2013-01-30 |
2023-08-12 |
rat |
| Whitney M Weikum, Tim F Oberlander, Takao K Hensch, Janet F Werke. Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception. Proceedings of the National Academy of Sciences of the United States of America. vol 109 Suppl 2. 2013-01-16. PMID:23045665. |
notably, serotonin reuptake inhibitors (sris) are antidepressant agents increasingly prescribed to manage antenatal mood disorders, and depressed maternal mood per se during pregnancy impacts infant behavior, also raising concerns about long-term consequences following such developmental exposure. |
2013-01-16 |
2023-08-12 |
Not clear |