| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Agren, L Reibrin. PET studies of presynaptic monoamine metabolism in depressed patients and healthy volunteers. Pharmacopsychiatry. vol 27. issue 1. 1994-05-19. PMID:8159778. |
no deranged presynaptic monoamine metabolism in the brain has been directly demonstrated in mood disorders, in spite of the rich but indirect pharmacological evidence for a decreased efficacy of monoaminergic synaptic transmission in depression, especially as for serotonin. |
1994-05-19 |
2023-08-12 |
human |
| S M Tejani-Butt, J Yang, A Kavian. Time course of altered thyroid states on 5-HT1A receptors and 5-HT uptake sites in rat brain: an autoradiographic analysis. Neuroendocrinology. vol 57. issue 6. 1993-12-22. PMID:8232759. |
since the serotonin (5-ht) system appears to be involved in the pathophysiology of mood disorders, the time course of the effects of thyroidectomy (txt) with or without thyroxine (t4) replacement on 5-ht1a receptors and 5-ht uptake sites was examined. |
1993-12-22 |
2023-08-12 |
rat |
| J J López-Ibo. Masked depression under the light of the new biological and nosological research. L'Encephale. vol 18 Spec No 1. 1992-07-13. PMID:1600902. |
the serotonin involvement in a wide range of conditions (such as depressions and other mood disorders, anxiety disorders, suicidal and aggressive behaviours, impulsive control disorders) has been explained through the common link of serotonin deficiency in disorders and behaviours characterized by a poor control of impulses (multi-impulsive disorders). |
1992-07-13 |
2023-08-11 |
Not clear |
| J J López-Ibo. Masked depression under the light of the new biological and nosological research. L'Encephale. vol 18 Spec No 1. 1992-07-13. PMID:1600902. |
but, the recent description of the so-called recurrent brief depressive episodes raises the question if those serotonin related conditions could be diagnosed as mood disorders. |
1992-07-13 |
2023-08-11 |
Not clear |
| A Young, G M Goodwi. Studies on central nervous system serotonin receptors in mood disorders. Annals of the Academy of Medicine, Singapore. vol 20. issue 1. 1991-06-13. PMID:2029163. |
studies on central nervous system serotonin receptors in mood disorders. |
1991-06-13 |
2023-08-11 |
Not clear |
| A Young, G M Goodwi. Studies on central nervous system serotonin receptors in mood disorders. Annals of the Academy of Medicine, Singapore. vol 20. issue 1. 1991-06-13. PMID:2029163. |
the evidence from studies of central nervous system serotonin (5-ht) receptors is reviewed and the role of these in the pathogenesis of mood disorders is discussed. |
1991-06-13 |
2023-08-11 |
Not clear |
| A Young, G M Goodwi. Studies on central nervous system serotonin receptors in mood disorders. Annals of the Academy of Medicine, Singapore. vol 20. issue 1. 1991-06-13. PMID:2029163. |
clinical evidence indicates that 5-ht function is abnormal in mood disorders. |
1991-06-13 |
2023-08-11 |
Not clear |
| M S Eiso. The new generation of serotonergic anxiolytics: possible clinical roles. Psychopathology. vol 22 Suppl 1. 1989-07-03. PMID:2567037. |
it appears that serotonin plays a role in multiple psychopathologies, including anxiety, depression, mood disorders, aggressive acting out, alcohol-related syndromes, and disinhibitory disorders characterized by impulsivity. |
1989-07-03 |
2023-08-11 |
Not clear |
| M E Trulson, T Cris. Calcium regulates the activity of serotonin-containing dorsal raphe neurons in vitro. Brain research bulletin. vol 15. issue 2. 1985-11-06. PMID:2412664. |
these findings may have implications for the treatment of mood disorders, for which disturbances in both calcium and serotonin metabolism have been demonstrated. |
1985-11-06 |
2023-08-11 |
mouse |