| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bradford D Fischer, Cojen Ho, Igor Kuzin, Andrea Bottaro, Michael E O'Lear. Chronic exposure to tumor necrosis factor in vivo induces hyperalgesia, upregulates sodium channel gene expression and alters the cellular electrophysiology of dorsal root ganglion neurons. Neuroscience letters. vol 653. 2018-04-30. PMID:28558976. |
the goal of these studies was to investigate the links between chronic exposure to the pro-inflammatory cytokine tumor necrosis factor (tnf), hyperalgesia and the excitability of dorsal root ganglion (drg) sensory neurons. |
2018-04-30 |
2023-08-13 |
mouse |
| J Q Fang, J Y Du, J F Fang, T Xiao, X Q Le, N F Pan, J Yu, B Y Li. Parameter-specific analgesic effects of electroacupuncture mediated by degree of regulation TRPV1 and P2X3 in inflammatory pain in rats. Life sciences. vol 200. 2018-04-05. PMID:29550358. |
observing the parameter-specific anti-hyperalgesic effects of ea with different stimulation times and frequencies on painful hyperalgesia mediated by the level of trpv1 and p2x3 expression in drg after cfa injection. |
2018-04-05 |
2023-08-13 |
rat |
| Lu Chang, Fang Ye, Quehua Luo, Yuanxiang Tao, Haihua Sh. Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats. Anesthesia and analgesia. vol 126. issue 1. 2018-01-02. PMID:29135586. |
increased hyperalgesia and proinflammatory cytokines in the spinal cord and dorsal root ganglion after surgery and/or fentanyl administration in rats. |
2018-01-02 |
2023-08-13 |
rat |
| Lu Chang, Fang Ye, Quehua Luo, Yuanxiang Tao, Haihua Sh. Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats. Anesthesia and analgesia. vol 126. issue 1. 2018-01-02. PMID:29135586. |
in this study, we tried to investigate behavioral hyperalgesia, the expression of proinflammatory cytokines, such as interleukin-1β (il-1β), interleukin-6 (il-6), and tumor necrosis factor-α (tnf-α), and the activation of microglia in the spinal cord and dorsal root ganglion (drg) in a rat model of surgical plantar incision with or without perioperative fentanyl. |
2018-01-02 |
2023-08-13 |
rat |
| Lei Gao, Yumei Zheng, Chengbo Zhao, Hongtao Ten. Investigation on effect of basalin coated silver nanoparticles as antioxidant for alleviating peripheral neuropathy in mice treated with oxaliplatin. Journal of photochemistry and photobiology. B, Biology. vol 177. 2017-12-19. PMID:29069632. |
moreover, behavioral analyses also manifested that the accumulation of aluminum on the drg might be a reason for neuropathic hyperalgesia. |
2017-12-19 |
2023-08-13 |
mouse |
| Nan Li, Linlin Zhang, Ruichen Shu, Ling Ding, Zhifen Wang, Haiyun Wang, Yonghao Yu, Guolin Wan. Involvement of CCL3/CCR5 Signaling in Dorsal Root Ganglion in Remifentanil-induced Hyperalgesia in Rats. The Clinical journal of pain. vol 32. issue 8. 2017-12-13. PMID:26550961. |
involvement of ccl3/ccr5 signaling in dorsal root ganglion in remifentanil-induced hyperalgesia in rats. |
2017-12-13 |
2023-08-13 |
rat |
| Nan Li, Linlin Zhang, Ruichen Shu, Ling Ding, Zhifen Wang, Haiyun Wang, Yonghao Yu, Guolin Wan. Involvement of CCL3/CCR5 Signaling in Dorsal Root Ganglion in Remifentanil-induced Hyperalgesia in Rats. The Clinical journal of pain. vol 32. issue 8. 2017-12-13. PMID:26550961. |
several mechanisms of remifentanil-induced hyperalgesia in spinal cord mainly have been explained such as n-methyl-d-aspartate receptors activation, but the mechanism in dorsal root ganglion (drg) is poorly understood. |
2017-12-13 |
2023-08-13 |
rat |
| Nan Li, Linlin Zhang, Ruichen Shu, Ling Ding, Zhifen Wang, Haiyun Wang, Yonghao Yu, Guolin Wan. Involvement of CCL3/CCR5 Signaling in Dorsal Root Ganglion in Remifentanil-induced Hyperalgesia in Rats. The Clinical journal of pain. vol 32. issue 8. 2017-12-13. PMID:26550961. |
in this paper we explored whether ccl3 and ccr5, the mainly receptor of ccl3, play a role in the remifentanil-induced hyperalgesia in drg by using a rat model with remifentanil administration. |
2017-12-13 |
2023-08-13 |
rat |
| De-Li Cao, Bin Qian, Zhi-Jun Zhang, Yong-Jing Gao, Xiao-Bo W. Chemokine receptor CXCR2 in dorsal root ganglion contributes to the maintenance of inflammatory pain. Brain research bulletin. vol 127. 2017-11-13. PMID:27697507. |
finally, perisciatic nerve injection of cxcr2 sirna to specifically knock down cxcr2 in the drg effectively attenuated cfa-induced mechanical allodynia and heat hyperalgesia, and the effect maintained for more than 5 days. |
2017-11-13 |
2023-08-13 |
Not clear |
| Ying Wang, Wen-Yuan Li, Hua Jia, Feng-Guo Zhai, Wen-Rui Qu, Yong-Xia Cheng, Yan-Cui Liu, Ling-Xiao Deng, Su-Fen Guo, Zai-Shun Ji. KLF7-transfected Schwann cell graft transplantation promotes sciatic nerve regeneration. Neuroscience. vol 340. 2017-11-07. PMID:27826105. |
additionally, hrp-labeled motoneurons in the spinal cord, ctb-labeled sensory neurons in the drg, motor endplate density and the weight ratios of target muscles were increased by the treatment while thermal hyperalgesia was diminished. |
2017-11-07 |
2023-08-13 |
mouse |
| C Johnson, G R Miller, B A Baker, M Hollander, M L Kashon, S Waugh, K Krajna. Changes in the expression of calcitonin gene-related peptide after exposure to injurious stretch-shortening contractions. Experimental gerontology. vol 79. 2017-09-25. PMID:26972633. |
the goal of this study was to determine if skeletal muscle injury induced by exposure to injurious stretch-shortening cycles (isscs), resulted in hyperalgesia in the hind limb and changes in calcitonin-gene related peptide (cgrp) immunolabeling in the dorsal root ganglia (drg) in young and old male rats. |
2017-09-25 |
2023-08-13 |
rat |
| Qiong Xiang, Chao Yu, Yao-Feng Zhu, Chun-Yan Li, Rong-Bo Tian, Xian-Hui L. Nuclear factor erythroid 2-related factor 2 antibody attenuates thermal hyperalgesia in the dorsal root ganglion: Neurochemical changes and behavioral studies after sciatic nerve-pinch injury. Injury. vol 47. issue 8. 2017-09-11. PMID:27316447. |
nuclear factor erythroid 2-related factor 2 antibody attenuates thermal hyperalgesia in the dorsal root ganglion: neurochemical changes and behavioral studies after sciatic nerve-pinch injury. |
2017-09-11 |
2023-08-13 |
mouse |
| Zhifeng Gao, Yi Feng, Hui J. The Different Dynamic Changes of Nerve Growth Factor in the Dorsal Horn and Dorsal Root Ganglion Leads to Hyperalgesia and Allodynia in Diabetic Neuropathic Pain. Pain physician. vol 20. issue 4. 2017-07-17. PMID:28535564. |
the different dynamic changes of nerve growth factor in the dorsal horn and dorsal root ganglion leads to hyperalgesia and allodynia in diabetic neuropathic pain. |
2017-07-17 |
2023-08-13 |
Not clear |
| Xiong Gan, Jing Wu, Cuixia Ren, Chun-Yu Qiu, Yan-Kun Li, Wang-Ping H. Potentiation of acid-sensing ion channel activity by peripheral group I metabotropic glutamate receptor signaling. Pharmacological research. vol 107. 2017-03-27. PMID:26946972. |
potentiation of asic activity by group i mglur signaling in rat drg neurons revealed a novel peripheral mechanism underlying group i mglurs involvement in hyperalgesia. |
2017-03-27 |
2023-08-13 |
rat |
| Rui Li, Li-Guo Wang, Qi Wang, Zhi-Hua Li, Ya-Li Ma, Qing-Duo Gu. Silencing of IRF3 alleviates chronic neuropathic pain following chronic constriction injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 88. 2017-03-20. PMID:28122305. |
intrathecal short-hairpin rna (shrna)-irf3 attenuated mechanical allodynia and thermal hyperalgesia in cci rats, as well as inhibited the production of tnf-α and il-1β in the drg of cci rats. |
2017-03-20 |
2023-08-13 |
rat |
| Lei Li, Ting Yu, Liling Yu, Haijun Li, Yongjuan Liu, Dongqin Wan. Exogenous brain-derived neurotrophic factor relieves pain symptoms of diabetic rats by reducing excitability of dorsal root ganglion neurons. The International journal of neuroscience. vol 126. issue 8. 2017-03-10. PMID:26441011. |
enhanced excitability of dorsal root ganglion (drg) neuron plays a crucial role in the progression of diabetic neuropathic hyperalgesia. |
2017-03-10 |
2023-08-13 |
rat |
| Lei Li, Ting Yu, Liling Yu, Haijun Li, Yongjuan Liu, Dongqin Wan. Exogenous brain-derived neurotrophic factor relieves pain symptoms of diabetic rats by reducing excitability of dorsal root ganglion neurons. The International journal of neuroscience. vol 126. issue 8. 2017-03-10. PMID:26441011. |
the results showed that continued intrathecal administration of bdnf to diabetic rats dramatically alleviated mechanical and thermal hyperalgesia, as well as inhibited hyperexcitability of drg neurons. |
2017-03-10 |
2023-08-13 |
rat |
| Liuming Jiang, Qun Wu, Tao Yan. Silencing of Id2 Alleviates Chronic Neuropathic Pain Following Chronic Constriction Injury. Journal of molecular neuroscience : MN. vol 59. issue 1. 2017-03-10. PMID:26768262. |
intrathecal short-hairpin rna (shrna)-id2 attenuates mechanical allodynia and thermal hyperalgesia in cci rats, and inhibits the expression of tnf-α and il-1β in the drg in cci rats. |
2017-03-10 |
2023-08-13 |
rat |
| Kyoji Taguch. [Role of Transient Receptor Potential Channels in Paclitaxel- and Oxaliplatin-induced Peripheral Neuropathy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 136. issue 2. 2016-12-26. PMID:26831807. |
(2) trpa1 expression via activation of p38 mitogen-activated protein kinase in small-diameter drg neurons, at least in part, contributes to the development of oxaliplatin-induced acute cold hyperalgesia. |
2016-12-26 |
2023-08-13 |
rat |
| Claudia Cervantes-Durán, Guadalupe C Vidal-Cantú, Beatriz Godínez-Chaparro, Vinicio Granados-Sot. Role of spinal 5-HT2 receptors subtypes in formalin-induced long-lasting hypersensitivity. Pharmacological reports : PR. vol 68. issue 2. 2016-12-13. PMID:26922550. |
the purpose of this study was to determine the role of spinal 5-ht2a, 5-ht2b and 5-ht2c receptors in the development and maintenance of formalin-induced long-lasting secondary allodynia and hyperalgesia in rats, as well as their expression in the dorsal root ganglia (drg) during this process. |
2016-12-13 |
2023-08-13 |
rat |