| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiong Xiang, Jing-Jing Li, Chun-Yan Li, Rong-Bo Tian, Xian-Hui L. Somatostatin Type 2 Receptor Antibody Enhances Mechanical Hyperalgesia in the Dorsal Root Ganglion Neurons after Sciatic Nerve-pinch Injury: Evidence of Behavioral Studies and Bax Protein Expression. CNS & neurological disorders drug targets. vol 18. issue 10. 2020-10-13. PMID:31686636. |
somatostatin type 2 receptor antibody enhances mechanical hyperalgesia in the dorsal root ganglion neurons after sciatic nerve-pinch injury: evidence of behavioral studies and bax protein expression. |
2020-10-13 |
2023-08-13 |
mouse |
| Xiaolan Cheng, Jiege Huo, Dawei Wang, Xueting Cai, Xiaoyan Sun, Wuguang Lu, Yang Yang, Chunping Hu, Xiaoning Wang, Peng Ca. Herbal Medicine AC591 Prevents Oxaliplatin-Induced Peripheral Neuropathy in Animal Model and Cancer Patients. Frontiers in pharmacology. vol 8. 2020-10-01. PMID:28638341. |
our results showed that pretreatment with ac591 reduced oxaliplatin-induced cold hyperalgesia, mechanical allodynia as well as morphological damage of dorsal root ganglion. |
2020-10-01 |
2023-08-13 |
mouse |
| Hee Kee Kim, Seon-Hee Hwang, Elizabeth Oh, Salahadin Abd. Rolipram, a Selective Phosphodiesterase 4 Inhibitor, Ameliorates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain through Inhibition of Inflammatory Cytokines in the Dorsal Root Ganglion. Frontiers in pharmacology. vol 8. 2020-10-01. PMID:29255417. |
rolipram, a selective phosphodiesterase 4 inhibitor, ameliorates mechanical hyperalgesia in a rat model of chemotherapy-induced neuropathic pain through inhibition of inflammatory cytokines in the dorsal root ganglion. |
2020-10-01 |
2023-08-13 |
rat |
| Chengcheng Song, Peng Liu, Qi Zhao, Suqian Guo, Guolin Wan. TRPV1 channel contributes to remifentanil-induced postoperative hyperalgesia via regulation of NMDA receptor trafficking in dorsal root ganglion. Journal of pain research. vol 12. 2020-10-01. PMID:30863139. |
trpv1 channel contributes to remifentanil-induced postoperative hyperalgesia via regulation of nmda receptor trafficking in dorsal root ganglion. |
2020-10-01 |
2023-08-13 |
Not clear |
| Song Cao, Qingmei Li, Jingfeng Hou, Zhourui Li, Xinya Cao, Xiaohong Liu, Bangyong Qi. Intrathecal TRPM8 blocking attenuates cold hyperalgesia via PKC and NF-κB signaling in the dorsal root ganglion of rats with neuropathic pain. Journal of pain research. vol 12. 2020-10-01. PMID:31114308. |
intrathecal trpm8 blocking attenuates cold hyperalgesia via pkc and nf-κb signaling in the dorsal root ganglion of rats with neuropathic pain. |
2020-10-01 |
2023-08-13 |
rat |
| Yong Fang Zhu, Robert Ungard, Natalie Zacal, Jan D Huizinga, James L Henry, Gurmit Sing. Rat model of cancer-induced bone pain: changes in nonnociceptive sensory neurons in vivo. Pain reports. vol 2. issue 4. 2020-09-29. PMID:29392218. |
in a previous investigation of an animal model of cibp, we have observed that changes in intrinsic membrane properties and excitability of dorsal root ganglion (drg) nociceptive neurons correspond to mechanical allodynia and hyperalgesia. |
2020-09-29 |
2023-08-13 |
rat |
| Jing Wen, Yong Yang, Shaogen Wu, Guihua Wei, Shushan Jia, Stephen Hannaford, Yuan-Xiang Ta. Long noncoding RNA H19 in the injured dorsal root ganglion contributes to peripheral nerve injury-induced pain hypersensitivity. Translational perioperative and pain medicine. vol 7. issue 2. 2020-09-28. PMID:32099850. |
microinjection of a specific h19 sirna, but not negative control scrambled sirna, into the injured drg 4 days before snl alleviated mechanical allodynia and thermal hyperalgesia on days 3 and 5 post-snl. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jing Wen, Yong Yang, Shaogen Wu, Guihua Wei, Shushan Jia, Stephen Hannaford, Yuan-Xiang Ta. Long noncoding RNA H19 in the injured dorsal root ganglion contributes to peripheral nerve injury-induced pain hypersensitivity. Translational perioperative and pain medicine. vol 7. issue 2. 2020-09-28. PMID:32099850. |
additionally, drg microinjection of the h19 sirna on day 7 after snl reduced mechanical allodynia and thermal hyperalgesia on days 10 and 12 post-snl. |
2020-09-28 |
2023-08-13 |
Not clear |
| Amanda Ferreira Neves, Felipe Hertzing Farias, Silviane Fernandes de Magalhães, Dionéia Araldi, Marco Pagliusi, Claudia Herrera Tambeli, Cesar Renato Sartori, Celina Monteiro da Cruz Lotufo, Carlos Amílcar Parad. Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells. Frontiers in physiology. vol 11. 2020-09-28. PMID:32523543. |
therefore, here we investigated whether activation of p2x7r by atp and the subsequent release of il-1β in drg participate in peripheral inflammatory hyperalgesia. |
2020-09-28 |
2023-08-13 |
Not clear |
| Hiroki Wakabayashi, Sho Kato, Nobuto Nagao, Gaku Miyamura, Yohei Naito, Akihiro Sud. Interleukin-6 Inhibitor Suppresses Hyperalgesia Without Improvement in Osteoporosis in a Mouse Pain Model of Osteoporosis. Calcified tissue international. vol 104. issue 6. 2020-08-28. PMID:30666355. |
ovariectomy induced bone loss and mechanical hyperalgesia in the hindlimbs with upregulation of cgrp expression in the drg neurons innervating the hindlimbs. |
2020-08-28 |
2023-08-13 |
mouse |
| Hiroki Wakabayashi, Sho Kato, Nobuto Nagao, Gaku Miyamura, Yohei Naito, Akihiro Sud. Interleukin-6 Inhibitor Suppresses Hyperalgesia Without Improvement in Osteoporosis in a Mouse Pain Model of Osteoporosis. Calcified tissue international. vol 104. issue 6. 2020-08-28. PMID:30666355. |
although anti-il-6r antibody treatment had no effect on ovariectomy-induced bone loss, the treatment prevented ovariectomy-induced mechanical hyperalgesia in the hindlimbs and suppressed cgrp expression in drg neurons. |
2020-08-28 |
2023-08-13 |
mouse |
| Fan Zhang, Sylvain Gigout, Yu Liu, Yiying Wang, Han Hao, Noel J Buckley, Hailin Zhang, Ian C Wood, Nikita Gampe. Repressor element 1-silencing transcription factor drives the development of chronic pain states. Pain. vol 160. issue 10. 2020-08-24. PMID:31206463. |
viral overexpression of rest in mouse dorsal root ganglion (drg) induced prominent mechanical and thermal hyperalgesia in vivo. |
2020-08-24 |
2023-08-13 |
mouse |
| Hui Kan Hong, Yi Ma, Hengtao Xi. TRPV1 and spinal astrocyte activation contribute to remifentanil-induced hyperalgesia in rats. Neuroreport. vol 30. issue 16. 2020-07-14. PMID:31568203. |
continuing infusion of remifentanil induced thermal hyperalgesia and mechanical allodynia, which were accompanied by upregulation of trpv1 and pkc protein in dorsal root ganglion. |
2020-07-14 |
2023-08-13 |
rat |
| Lin Chen, Changlong Leng, Xiaokang Gong, Baomiao Ma, Qin Ru, Qi Xiong, Mei Zhou, Xiang Tian, Kai Yue, Chaoying Li, Yuxiang W. 2 Hz EA Reduces Heroin Withdrawal-Induced Hyperalgesia and Heroin Relapse by Downregulating P2X3 Receptors in DRG Neurons. BioMed research international. vol 2019. 2020-07-02. PMID:31950033. |
2 hz ea reduces heroin withdrawal-induced hyperalgesia and heroin relapse by downregulating p2x3 receptors in drg neurons. |
2020-07-02 |
2023-08-13 |
rat |
| Lin Chen, Changlong Leng, Xiaokang Gong, Baomiao Ma, Qin Ru, Qi Xiong, Mei Zhou, Xiang Tian, Kai Yue, Chaoying Li, Yuxiang W. 2 Hz EA Reduces Heroin Withdrawal-Induced Hyperalgesia and Heroin Relapse by Downregulating P2X3 Receptors in DRG Neurons. BioMed research international. vol 2019. 2020-07-02. PMID:31950033. |
our previous study demonstrated that the upregulation of p2x3 receptors in the dorsal root ganglia (drg) might participate in heroin withdrawal-induced hyperalgesia. |
2020-07-02 |
2023-08-13 |
rat |
| Lin Chen, Changlong Leng, Xiaokang Gong, Baomiao Ma, Qin Ru, Qi Xiong, Mei Zhou, Xiang Tian, Kai Yue, Chaoying Li, Yuxiang W. 2 Hz EA Reduces Heroin Withdrawal-Induced Hyperalgesia and Heroin Relapse by Downregulating P2X3 Receptors in DRG Neurons. BioMed research international. vol 2019. 2020-07-02. PMID:31950033. |
after being treated using 2 hz ea, reinstatement was reduced, hyperalgesia was decreased, and the upregulated expression of p2x3 receptors in the drg had decreased significantly compared to that in the heroin-addicted group. |
2020-07-02 |
2023-08-13 |
rat |
| Lin Chen, Changlong Leng, Xiaokang Gong, Baomiao Ma, Qin Ru, Qi Xiong, Mei Zhou, Xiang Tian, Kai Yue, Chaoying Li, Yuxiang W. 2 Hz EA Reduces Heroin Withdrawal-Induced Hyperalgesia and Heroin Relapse by Downregulating P2X3 Receptors in DRG Neurons. BioMed research international. vol 2019. 2020-07-02. PMID:31950033. |
consequently, our results indicated that 2 hz ea was an effective method for treating heroin-induced hyperalgesia and helping prevent relapse, and the potential mechanism might be related to the downregulation of p2x3 receptor expression in the drg. |
2020-07-02 |
2023-08-13 |
rat |
| Lifang Zou, Kehua Yu, Yang Fan, Suixia Cao, Shuangmei Liu, Liran Shi, Lin Li, Huilong Yuan, Runan Yang, Zhihua Yi, Yun Gao, Guilin Li, Wolfgang Greffrath, Rolf-Detlef Treede, Man Li, Hong Xu, Chunping Zhang, Shangdong Lian. The Inhibition by Guanfu Base A of Neuropathic Pain Mediated by P2Y ACS chemical neuroscience. vol 10. issue 3. 2020-03-23. PMID:30475578. |
the inhibition by guanfu base a of neuropathic pain mediated by p2y activation of satellite glial cells (sgcs) in the dorsal root ganglia (drg) is involved in mechanical and thermal hyperalgesia. |
2020-03-23 |
2023-08-13 |
Not clear |
| Yuya Kawarai, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Miyako Suzuki, Kazuhide Inage, Shigeo Hagiwara, Takane Suzuki, Takayuki Nakajima, Tsutomu Akazawa, Seiji Ohtor. Analgesic Effect of Duloxetine on an Animal Model of Monosodium Iodoacetate-Induced Hip Osteoarthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 38. issue 2. 2020-02-10. PMID:31538672. |
we investigated the efficacy of duloxetine on hyperalgesia, histopathological and radiographic findings, pain-related sensory innervation of dorsal-root ganglia (drg), and spinal changes in a rat model of induced hip osteoarthritis (oa). |
2020-02-10 |
2023-08-13 |
rat |
| Yuya Kawarai, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Miyako Suzuki, Kazuhide Inage, Shigeo Hagiwara, Takane Suzuki, Takayuki Nakajima, Tsutomu Akazawa, Seiji Ohtor. Analgesic Effect of Duloxetine on an Animal Model of Monosodium Iodoacetate-Induced Hip Osteoarthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 38. issue 2. 2020-02-10. PMID:31538672. |
we assessed hyperalgesia, histopathological changes, immunoreactive (-ir) neurons for calcitonin gene-related peptide and activating transcription factor 3 in drg, and immunoreactive neurons for ionized-calcium-binding adaptor molecule 1 (iba1) in the dorsal horn of the spinal cord. |
2020-02-10 |
2023-08-13 |
rat |