| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan-Bo Yu, Jing Yang, Xiu-Li Zuo, Li-Jun Gao, Peng Wang, Yan-Qing L. Transient receptor potential vanilloid-1 (TRPV1) and ankyrin-1 (TRPA1) participate in visceral hyperalgesia in chronic water avoidance stress rat model. Neurochemical research. vol 35. issue 5. 2010-07-08. PMID:20182791. |
the results indicate that was could induce the upregulation of trpv1 and trpa1 in the colonic afferent drg, and both receptors may be candidate molecules involved in the stress-induced visceral hyperalgesia in rats. |
2010-07-08 |
2023-08-12 |
rat |
| H-G Schaible, G Segond von Banchet, M K Boettger, R Bräuer, M Gajda, F Richter, S Hensellek, D Brenn, G Natur. The role of proinflammatory cytokines in the generation and maintenance of joint pain. Annals of the New York Academy of Sciences. vol 1193. 2010-05-18. PMID:20398009. |
finally, in cultured drg neurons tnf-alpha increased the proportion of neurons that express the trpv1 receptor and may thus contribute to the generation of inflammation-evoked thermal hyperalgesia. |
2010-05-18 |
2023-08-12 |
rat |
| Y Kajihara, M Murakami, T Imagawa, K Otsuguro, S Ito, T Oht. Histamine potentiates acid-induced responses mediating transient receptor potential V1 in mouse primary sensory neurons. Neuroscience. vol 166. issue 1. 2010-05-04. PMID:20006972. |
carrageenan and complete freund's adjuvant produced inflammatory hyperalgesia, but these inflammatory conditions did not change the potentiating effects of histamine in drg neurons. |
2010-05-04 |
2023-08-12 |
mouse |
| Xin-Li Ding, Yong-Hui Wang, Li-Ping Ning, Yang Zhang, Hong-You Ge, Hong Jiang, Rong Wang, Shou-Wei Yu. Involvement of TRPV4-NO-cGMP-PKG pathways in the development of thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats. Behavioural brain research. vol 208. issue 1. 2010-05-03. PMID:19948193. |
involvement of trpv4-no-cgmp-pkg pathways in the development of thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats. |
2010-05-03 |
2023-08-12 |
rat |
| Xin-Li Ding, Yong-Hui Wang, Li-Ping Ning, Yang Zhang, Hong-You Ge, Hong Jiang, Rong Wang, Shou-Wei Yu. Involvement of TRPV4-NO-cGMP-PKG pathways in the development of thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats. Behavioural brain research. vol 208. issue 1. 2010-05-03. PMID:19948193. |
the aim of the present study was to test the hypothesis that the trpv4-no-cgmp-pkg cascade is involved in the maintenance of thermal hyperalgesia following chronic compression of the dorsal root ganglion (drg) (the procedure hereafter termed ccd) in rats. |
2010-05-03 |
2023-08-12 |
rat |
| Severine Stamboulian, Jin-Sung Choi, Hye-Sook Ahn, Yu-Wen Chang, Lynda Tyrrell, Joel A Black, Stephen G Waxman, Sulayman D Dib-Haj. ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 5. 2010-03-05. PMID:20130174. |
for example, neurotrophic growth factor activates (phosphorylates) erk1/2 mapk (perk1/2) in drg neurons, an effect that has been implicated in injury-induced hyperalgesia. |
2010-03-05 |
2023-08-12 |
Not clear |
| Richard B Messinger, Ajit K Naik, Miljen M Jagodic, Michael T Nelson, Woo Yong Lee, Won Joo Choe, Peihan Orestes, Janelle R Latham, Slobodan M Todorovic, Vesna Jevtovic-Todorovi. In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy. Pain. vol 145. issue 1-2. 2009-11-17. PMID:19577366. |
earlier, we showed that streptozocin (stz)-induced type 1 diabetes in rats leads to the development of painful peripheral diabetic neuropathy (pdn) manifested as thermal hyperalgesia and mechanical allodynia accompanied by significant enhancement of t-type calcium currents (t-currents) and cellular excitability in medium-sized dorsal root ganglion (drg) neurons. |
2009-11-17 |
2023-08-12 |
rat |
| Munetaka Suzuki, Gen Inoue, Takefumi Gemba, Tomoko Watanabe, Toshinori Ito, Takana Koshi, Kazuyo Yamauchi, Masaomi Yamashita, Sumihisa Orita, Yawara Eguchi, Nobuyasu Ochiai, Shunji Kishida, Masashi Takaso, Yasuchika Aoki, Kazuhisa Takahashi, Seiji Ohtor. Nuclear factor-kappa B decoy suppresses nerve injury and improves mechanical allodynia and thermal hyperalgesia in a rat lumbar disc herniation model. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 18. issue 7. 2009-10-20. PMID:19308465. |
we investigated the transduction efficiency of nf-kappab decoy to dorsal root ganglion (drg), as well as the decrease in nerve injury, mechanical allodynia, and thermal hyperalgesia in a rat lumbar disc herniation model. |
2009-10-20 |
2023-08-12 |
rat |
| T Kawano, V Zoga, J B McCallum, H-E Wu, G Gemes, M-Y Liang, S Abram, W-M Kwok, Q H Hogan, C D Sarantopoulo. ATP-sensitive potassium currents in rat primary afferent neurons: biophysical, pharmacological properties, and alterations by painful nerve injury. Neuroscience. vol 162. issue 2. 2009-09-16. PMID:19422886. |
we therefore characterized these channels in dorsal root ganglion (drg) neurons, and tested whether they contribute to hyperalgesia after spinal nerve ligation (snl). |
2009-09-16 |
2023-08-12 |
rat |
| Giuseppe D'Agostino, Giovanna La Rana, Roberto Russo, Oscar Sasso, Anna Iacono, Emanuela Esposito, Giuseppina Mattace Raso, Salvatore Cuzzocrea, Jesse Loverme, Daniele Piomelli, Rosaria Meli, Antonio Calignan. Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia. European journal of pharmacology. vol 613. issue 1-3. 2009-08-28. PMID:19386271. |
to investigate the mechanism by which pea attenuated hyperalgesia, we evaluated inhibitory kb-alpha (ikb-alpha) degradation and p65 nuclear factor kb (nf-kappab) activation in drg. |
2009-08-28 |
2023-08-12 |
mouse |
| Masahiko Ikeuchi, Sandra J Kolker, Kathleen A Sluk. Acid-sensing ion channel 3 expression in mouse knee joint afferents and effects of carrageenan-induced arthritis. The journal of pain. vol 10. issue 3. 2009-05-13. PMID:19185546. |
of the acid-sensing ion channels (asic), asic3 is most sensitive to such a ph change, abundantly expressed in dorsal root ganglion (drg), and critical for the development of secondary hyperalgesia. |
2009-05-13 |
2023-08-12 |
mouse |
| Joanna Mika, Michal Korostynski, Dorota Kaminska, Agnieszka Wawrzczak-Bargiela, Maria Osikowicz, Wioletta Makuch, Ryszard Przewlocki, Barbara Przewlock. Interleukin-1 alpha has antiallodynic and antihyperalgesic activities in a rat neuropathic pain model. Pain. vol 138. issue 3. 2009-04-21. PMID:18374486. |
to study the potential role of il-1 in the pathogenesis of allodynia and hyperalgesia, il-1alpha and comparative il-1beta, il-6, and il-10 mrna levels were quantified using competitive rt-pcr of the lumbar spinal cord and dorsal root ganglia (drg; l5-l6) three and seven days after chronic constriction injury (cci) in rats. |
2009-04-21 |
2023-08-12 |
rat |
| Xue-Song Song, Zhi-Jiang Huang, Xue-Jun Son. Thiamine suppresses thermal hyperalgesia, inhibits hyperexcitability, and lessens alterations of sodium currents in injured, dorsal root ganglion neurons in rats. Anesthesiology. vol 110. issue 2. 2009-03-05. PMID:19194165. |
thiamine suppresses thermal hyperalgesia, inhibits hyperexcitability, and lessens alterations of sodium currents in injured, dorsal root ganglion neurons in rats. |
2009-03-05 |
2023-08-12 |
rat |
| Lu Yu, Fei Yang, Hao Luo, Feng-Yu Liu, Ji-Sheng Han, Guo-Gang Xing, You Wa. The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant. Molecular pain. vol 4. 2009-02-13. PMID:19055783. |
the present study aims to investigate the role of transient receptor potential vanilloid 1 (trpv1) in dorsal root ganglion (drg) neurons in chronic pain including thermal hyperalgesia and mechanical allodynia. |
2009-02-13 |
2023-08-12 |
rat |
| Thi Aurore Pham-Marcou, Hélène Beloeil, Xueging Sun, Marc Gentili, Djouer Yaici, Gérard Benoit, Dan Benhamou, Jean-Xavier Mazoi. Antinociceptive effect of resveratrol in carrageenan-evoked hyperalgesia in rats: prolonged effect related to COX-2 expression impairment. Pain. vol 140. issue 2. 2009-01-13. PMID:18814970. |
we measured the antinociceptive effect of resveratrol on carrageenan-induced hyperalgesia, prostaglandin-e2 (pge2) concentration in csf and cox-1/cox-2 gene expression in the spinal cord and dorsal root ganglion (drg) in rats. |
2009-01-13 |
2023-08-12 |
rat |
| Jing Yang, Yanqing Li, Xiuli Zuo, Yanbo Zhen, Yanbo Yu, Lijun Ga. Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18583045. |
intrathecal administration of trpa1 antisense (as) oligodeoxynucleotide (odn) reduced the trpa1 expression in drg as well as suppressed the colitis-induced hyperalgesia to nociceptive colonic distension and intracolonic allyl isothiocyanate (aitc). |
2008-11-05 |
2023-08-12 |
Not clear |
| Xue-Jun Song, Jun-Li Cao, Hao-Chuan Li, Ji-Hong Zheng, Xue-Song Song, Li-Ze Xion. Upregulation and redistribution of ephrinB and EphB receptor in dorsal root ganglion and spinal dorsal horn neurons after peripheral nerve injury and dorsal rhizotomy. European journal of pain (London, England). vol 12. issue 8. 2008-10-30. PMID:18321739. |
the results showed that expression of ephrinb1 and ephb1 receptor proteins was significantly upregulated in drg and sc in a time-dependent manner corresponding to the development of thermal hyperalgesia after cci. |
2008-10-30 |
2023-08-12 |
rat |
| Lillian Cruz-Orengo, Ajay Dhaka, Robert J Heuermann, Timothy J Young, Michael C Montana, Eric J Cavanaugh, Donghee Kim, Gina M Stor. Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. Molecular pain. vol 4. 2008-10-20. PMID:18671867. |
a number of prostaglandins (pgs) sensitize dorsal root ganglion (drg) neurons and contribute to inflammatory hyperalgesia by signaling through specific g protein-coupled receptors (gpcrs). |
2008-10-20 |
2023-08-12 |
Not clear |
| Katharina Funk, Anne Woitecki, Christina Franjic-Würtz, Thomas Gensch, Frank Möhrlen, Stephan Fring. Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons. Molecular pain. vol 4. 2008-10-20. PMID:18700020. |
based on the hypothesis that modulation of the peripheral cl- homeostasis is involved in the generation of inflammatory hyperalgesia, we examined the effects of inflammatory mediators on intracellular cl- concentrations and on the expression levels of cl- transporters in rat drg neurons. |
2008-10-20 |
2023-08-12 |
human |
| Chun Xiao, Lin Zhang, Qiu-Ping Cheng, Li-Cai Zhan. The activation of extracellular signal-regulated protein kinase 5 in spinal cord and dorsal root ganglia contributes to inflammatory pain. Brain research. vol 1215. 2008-09-04. PMID:18486117. |
in this study, we investigated extracellular signal-regulated protein kinase 5 (erk5) activation by peripheral inflammation in the spinal cord and drg of rats and whether this activation contributes to a heat and mechanical hyperalgesia response. |
2008-09-04 |
2023-08-12 |
rat |