| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A P B Gontijo, M C Mancini, P L P Silva, P S C Chagas, R F Sampaio, R E Luz, S T Fonsec. Changes in lower limb co-contraction and stiffness by toddlers with Down syndrome and toddlers with typical development during the acquisition of independent gait. Human movement science. vol 27. issue 4. 2009-01-08. PMID:18649965. |
compared to typically developing toddlers (td), toddlers with down syndrome (ds) have functionally different musculoskeletal characteristics, such as hypotonia, and joint and ligament laxity, that could produce a reduced passive stiffness. |
2009-01-08 |
2023-08-12 |
Not clear |
| Emma L Jones, Marisa Margallo-Lana, Vee P Prasher, Clive G Ballar. The extended tau haplotype and the age of onset of dementia in Down syndrome. Dementia and geriatric cognitive disorders. vol 26. issue 3. 2009-01-08. PMID:18765933. |
most people with down syndrome (ds) develop alzheimer's disease (ad). |
2009-01-08 |
2023-08-12 |
Not clear |
| Gudmar Lönnerholm, Britt-Marie Frost, Stefan Söderhäll, Siebold S N de Graa. Vincristine pharmacokinetics in children with Down syndrome. Pediatric blood & cancer. vol 52. issue 1. 2009-01-07. PMID:18615507. |
children with down syndrome (ds), who represent about 2% of childhood acute lymphoblastic leukemia, have inferior prognosis compared to non-ds children. |
2009-01-07 |
2023-08-12 |
Not clear |
| Niketa Shah, Ali Al-Ahmari, Arwa Al-Yamani, Lee Dupuis, Derek Stephens, Johann Hitzle. Outcome and toxicity of chemotherapy for acute lymphoblastic leukemia in children with Down syndrome. Pediatric blood & cancer. vol 52. issue 1. 2009-01-07. PMID:18802938. |
acute lymphoblastic leukemia (all) in children with down syndrome (ds) presents with an increased incidence, higher frequency of adverse effects and inferior probability of survival. |
2009-01-07 |
2023-08-12 |
Not clear |
| Beth A Smith, Beverly D Ulric. Early onset of stabilizing strategies for gait and obstacles: older adults with Down syndrome. Gait & posture. vol 28. issue 3. 2009-01-06. PMID:18359229. |
our goal was to examine the gait patterns of older adults with down syndrome (ds) for precocious stabilizing adaptations during comfortable over-ground walking and in more challenging conditions. |
2009-01-06 |
2023-08-12 |
human |
| Manuela Galli, Chiara Rigoldi, Reinald Brunner, Naznin Virji-Babul, Albertini Giorgi. Joint stiffness and gait pattern evaluation in children with Down syndrome. Gait & posture. vol 28. issue 3. 2009-01-06. PMID:18455922. |
hypotonia, ligament laxity and motor alterations are characteristic for patients with down syndrome (ds). |
2009-01-06 |
2023-08-12 |
human |
| Seçil Ilhan Yilmaz, Halil Demirta. AgNOR increase in buccal epithelial cells of trisomy 21 infants. Micron (Oxford, England : 1993). vol 39. issue 8. 2009-01-06. PMID:18482842. |
the aim of this study is to compare the argilophilic nucleolus organizer regions (agnors) level between down syndrome (ds) patients and controls in a tissue sharing the same embryonic origin with the central nervous system and compare the results with those obtained recently by us from ds's lymphocytes. |
2009-01-06 |
2023-08-12 |
Not clear |
| G Pollonini, V Gao, A Rabe, S Palminiello, G Albertini, C M Alberin. Abnormal expression of synaptic proteins and neurotrophin-3 in the Down syndrome mouse model Ts65Dn. Neuroscience. vol 156. issue 1. 2009-01-05. PMID:18703118. |
down syndrome (ds) results from triplication of the whole or distal part of human chromosome 21. |
2009-01-05 |
2023-08-12 |
mouse |
| S W Moor. Down syndrome and the enteric nervous system. Pediatric surgery international. vol 24. issue 8. 2008-12-30. PMID:18633623. |
down syndrome (ds) is the most common chromosomal abnormality occurring in humans. |
2008-12-30 |
2023-08-12 |
human |
| Susan Shur-Fen Gau, Yen-Nan Chiu, Wei-Tsuen Soong, Ming-Been Le. Parental characteristics, parenting style, and behavioral problems among chinese children with Down syndrome, their siblings and controls in Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 107. issue 9. 2008-12-17. PMID:18796359. |
the literature has documented maternal distress and behavioral problems among children with down syndrome (ds), however, little is known about paternal adjustment and behavioural problems among the siblings of children with ds. |
2008-12-17 |
2023-08-12 |
Not clear |
| Hideki Muramatsu, Koji Kato, Nobuhiro Watanabe, Kimikazu Matsumoto, Tomohiko Nakamura, Yasuo Horikoshi, Junichi Mimaya, Chizuko Suzuki, Masahiro Hayakawa, Seiji Kojim. Risk factors for early death in neonates with Down syndrome and transient leukaemia. British journal of haematology. vol 142. issue 4. 2008-12-16. PMID:18510680. |
transient leukaemia (tl) in neonates with down syndrome (ds) is characterized by the transient appearance of blast cells in the peripheral blood that resolves spontaneously. |
2008-12-16 |
2023-08-12 |
Not clear |
| Ken C Lo, Jane Chalker, Sabine Strehl, Michael Neat, Owen Smith, Nicole Dastugue, Lyndal Kearney, Shai Izraeli, Helena Kempski, John K Cowel. Array comparative genome hybridization analysis of acute lymphoblastic leukaemia and acute megakaryoblastic leukaemia in patients with Down syndrome. British journal of haematology. vol 142. issue 6. 2008-12-11. PMID:18557744. |
twenty-five cases of b-cell precursor acute lymphoblastic leukaemia (all) from down syndrome (ds) patients were analyzed using array comparative genomic hybridization (acgh) and compared with two other subgroups of non-ds patients with all; five cases with high-hyperdiploidy (hh) and nine cases with etv6-runx1 positive clones. |
2008-12-11 |
2023-08-12 |
Not clear |
| Jerzy Wegiel, Karol Dowjat, Wojciech Kaczmarski, Izabela Kuchna, Krzysztof Nowicki, Janusz Frackowiak, Bozena Mazur Kolecka, Jarek Wegiel, Wayne P Silverman, Barry Reisberg, Mony Deleon, Thomas Wisniewski, Cheng-Xin Gong, Fei Liu, Tatyana Adayev, Mo-Chou Chen-Hwang, Yu-Wen Hwan. The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome. Acta neuropathologica. vol 116. issue 4. 2008-12-09. PMID:18696092. |
the gene encoding the minibrain kinase/dual-specificity tyrosine phosphorylated and regulated kinase 1a (dyrk1a) is located in the down syndrome (ds) critical region of chromosome 21. |
2008-12-09 |
2023-08-12 |
human |
| Samuel R Browd, J Steele McIntyre, Douglas Brockmeye. Failed age-dependent maturation of the occipital condyle in patients with congenital occipitoatlantal instability and Down syndrome: a preliminary analysis. Journal of neurosurgery. Pediatrics. vol 2. issue 5. 2008-12-02. PMID:18976108. |
the second objective of the study was to compare these data with measurements collected in patients with congenital occipitoatlantal instability (coi) or down syndrome (ds). |
2008-12-02 |
2023-08-12 |
Not clear |
| Jianhua Shi, Tianyi Zhang, Chunlei Zhou, Muhammad Omar Chohan, Xiaosong Gu, Jerzy Wegiel, Jianhua Zhou, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Cheng-Xin Gong, Fei Li. Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome. The Journal of biological chemistry. vol 283. issue 42. 2008-11-25. PMID:18658135. |
very early in their life, individuals with down syndrome (ds) develop alzheimer-type tau pathology, the molecular basis for which is not fully understood. |
2008-11-25 |
2023-08-12 |
human |
| Sébastien Malinge, Christine Ragu, Veronique Della-Valle, Didier Pisani, Stefan N Constantinescu, Christelle Perez, Jean-Luc Villeval, Dirk Reinhardt, Judith Landman-Parker, Lucienne Michaux, Nicole Dastugue, André Baruchel, William Vainchenker, Jean-Pierre Bourquin, Virginie Penard-Lacronique, Olivier A Bernar. Activating mutations in human acute megakaryoblastic leukemia. Blood. vol 112. issue 10. 2008-11-25. PMID:18755984. |
in a series of human amkl samples from both down syndrome and non-down syndrome patients, mutations were identified within kit, flt3, jak2, jak3, and mpl genes, with a higher frequency in ds than in non-ds patients. |
2008-11-25 |
2023-08-12 |
mouse |
| Nataly Apollonsky, Ashok Shende, Ihsane Ouansafi, Judith Brody, Mark Atlas, Banu Aygu. Transient myeloproliferative disorder in neonates with and without Down syndrome: a tale of 2 syndromes. Journal of pediatric hematology/oncology. vol 30. issue 11. 2008-11-25. PMID:18989165. |
transient myeloproliferative disorder (tmd) in newborns with down syndrome (ds) has been well described. |
2008-11-25 |
2023-08-12 |
Not clear |
| Hannah M Nash, Margaret J Snowlin. Semantic and phonological fluency in children with Down syndrome: atypical organization of language or less efficient retrieval strategies? Cognitive neuropsychology. vol 25. issue 5. 2008-11-18. PMID:18642139. |
in this study the verbal fluency procedure was used to investigate the organization of semantic and phonological representations in children with down syndrome (ds) and typically developing children, matched pairwise for receptive vocabulary age. |
2008-11-18 |
2023-08-12 |
Not clear |
| Sharath Asokan, M S Muthu, N Sivakuma. Oral findings of Down syndrome children in Chennai city, India. Indian journal of dental research : official publication of Indian Society for Dental Research. vol 19. issue 3. 2008-11-18. PMID:18797100. |
to assess the common oral findings and anomalies of down syndrome (ds) children in chennai city, india. |
2008-11-18 |
2023-08-12 |
Not clear |
| Jon Ortiz-Abalia, Ignasi Sahún, Xavier Altafaj, Núria Andreu, Xavier Estivill, Mara Dierssen, Cristina Filla. Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome. American journal of human genetics. vol 83. issue 4. 2008-11-18. PMID:18940310. |
genetic-dissection studies carried out with down syndrome (ds) murine models point to the critical contribution of dyrk1a overexpression to the motor abnormalities and cognitive deficits displayed in ds individuals. |
2008-11-18 |
2023-08-12 |
mouse |