| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patrice Flore, Véronique-A Bricout, Debbie van Biesen, Michel Guinot, François Laporte, Jean-Louis Pépin, Yves Eberhard, Anne Favre-Juvin, Bernard Wuyam, Peter van de Vliet, Patrice Faur. Oxidative stress and metabolism at rest and during exercise in persons with Down syndrome. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. vol 15. issue 1. 2008-06-26. PMID:18277183. |
down syndrome (ds) is a risk factor for metabolic syndrome and cardiovascular disease. |
2008-06-26 |
2023-08-12 |
Not clear |
| Ariko Takeuchi, Hiroaki Ehara, Kyoichi Ohtani, Yoshihiro Maegaki, Yukiko Nanba, Ikuo Nagata, Mitsuo Toyoshima, Akiko Kondo, Shoji Nakai, Kenzo Takeshita, Kousaku Ohn. Live birth prevalence of Down syndrome in Tottori, Japan, 1980-1999. American journal of medical genetics. Part A. vol 146A. issue 11. 2008-06-26. PMID:18412274. |
one hundred sixty-four patients with down syndrome (ds) were confirmed in tottori prefecture, japan, from 1980 to 1999. |
2008-06-26 |
2023-08-12 |
Not clear |
| M L Martínez-Fría. The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome. American journal of medical genetics. Part A. vol 146A. issue 11. 2008-06-26. PMID:18446861. |
studies on the structure of the methylenetetrahydrofolate reductase (mthfr) gene and the mechanisms by which folate may reduce homocysteine levels in bacteria and in humans have provided a rationale to understand the conflicting epidemiological observations between the studies on the 677c-t and 1298a-c mthfr polymorphic variants, and the risk of having an infant with down syndrome (ds). |
2008-06-26 |
2023-08-12 |
human |
| M Pritchard, R H Reeves, M Dierssen, D Patterson, K J Gardine. Down syndrome and the genes of human chromosome 21: current knowledge and future potentials. Report on the Expert workshop on the biology of chromosome 21 genes: towards gene-phenotype correlations in Down syndrome. Washington D.C., September 28-October 1, 2007. Cytogenetic and genome research. vol 121. issue 1. 2008-06-19. PMID:18544929. |
down syndrome (ds), trisomy of human chromosome 21, is the most common genetic cause of intellectual disability. |
2008-06-19 |
2023-08-12 |
human |
| Kasper Pihl, Tina Lindvig Sørensen, Bent Nørgaard-Pedersen, Severin Olesen Larsen, Tri Huu Nguyen, Lone Krebs, Torben Larsen, Michael Christianse. First-trimester combined screening for Down syndrome: prediction of low birth weight, small for gestational age and pre-term delivery in a cohort of non-selected women. Prenatal diagnosis. vol 28. issue 3. 2008-06-17. PMID:18302310. |
to establish the relationship between the first-trimester screening markers [pregnancy-associated plasma protein a (papp-a), free human chorionic gonadotrophin-beta (beta-hcg), nuchal translucency (nt)], the down syndrome (ds) risk estimate, and the adverse outcomes such as low birth weight, small for gestational age (sga) and pre-term delivery. |
2008-06-17 |
2023-08-12 |
human |
| Edmund C Jenkins, Flora Tassone, Lingling Ye, Hong Gu, Man Xi, Milen Velinov, W Ted Brown, Randi J Hagerman, Paul J Hagerma. Reduced telomere length in older men with premutation alleles of the fragile X mental retardation 1 gene. American journal of medical genetics. Part A. vol 146A. issue 12. 2008-06-16. PMID:18478592. |
reduced telomere length has recently been reported in t lymphocytes of individuals with trisomy 21 down syndrome (ds) and dementia. |
2008-06-16 |
2023-08-12 |
Not clear |
| Sarah L Ball, Anthony J Holland, Peter Treppner, Peter C Watson, Felicia A Hupper. Executive dysfunction and its association with personality and behaviour changes in the development of Alzheimer's disease in adults with Down syndrome and mild to moderate learning disabilities. The British journal of clinical psychology. vol 47. issue Pt 1. 2008-06-11. PMID:17681112. |
recent research suggests that preclinical alzheimer's disease (ad) in people with down syndrome (ds) is characterized by changes in personality/behaviour and executive dysfunction that are more prominent than deterioration in episodic memory. |
2008-06-11 |
2023-08-12 |
Not clear |
| Jianhua Wu, Dale A Ulrich, Julia Looper, Chad W Tiernan, Rosa M Angulo-Barros. Strategy adoption and locomotor adjustment in obstacle clearance of newly walking toddlers with Down syndrome after different treadmill interventions. Experimental brain research. vol 186. issue 2. 2008-06-11. PMID:18064443. |
this study investigated how newly walking toddlers with down syndrome (ds), after different treadmill interventions, adopted clearance strategies and modified anticipatory locomotor adjustment patterns to negotiate an obstacle in their travel path. |
2008-06-11 |
2023-08-12 |
Not clear |
| Yoko Miyoshi, Hitoshi Tajiri, Mariko Okaniwa, Sousuke Terasawa, Tomoo Fujisawa, Toshiyuki Iizuka, Keiichi Ozon. Hepatitis C virus infection and interferon therapy in patients with Down syndrome. Pediatrics international : official journal of the Japan Pediatric Society. vol 50. issue 1. 2008-06-11. PMID:18279197. |
the clinical features of hepatitis c virus (hcv)-associated liver diseases, or the efficacy of interferon (ifn) therapy in children with down syndrome (ds) remain to be elucidated. |
2008-06-11 |
2023-08-12 |
Not clear |
| Rosa Angulo-Barroso, Amy R Burghardt, Meghann Lloyd, Dale A Ulric. Physical activity in infants with Down syndrome receiving a treadmill intervention. Infant behavior & development. vol 31. issue 2. 2008-06-10. PMID:18045691. |
despite the recognized relevance of physical activity in the development and health of children, assessment of physical activity levels (pa-level) in infancy is limited, especially in infants with down syndrome (ds). |
2008-06-10 |
2023-08-12 |
Not clear |
| A Ypsilanti, G Grouio. Linguistic profile of individuals with Down syndrome: comparing the linguistic performance of three developmental disorders. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. vol 14. issue 2. 2008-06-10. PMID:18306077. |
an increasing number of studies, addressing the linguistic abilities of individuals with down syndrome (ds) suggest that they exhibit strengths and weaknesses within the linguistic domain. |
2008-06-10 |
2023-08-12 |
Not clear |
| Xiang-jun He, Qi Zhang, Li-ping Ma, Li-jun Yang, Huan Shen, Jing-zhu Gu. [Cell-cycle negative regulatory gene ANA is over-expressed in the brain tissues of patients with Down syndrome]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. vol 37. issue 6. 2008-06-09. PMID:16378112. |
to investigate the expression level of genes located in chromosome 21 in the brain tissues of down syndrome(ds). |
2008-06-09 |
2023-08-12 |
Not clear |
| Romain Favre, Grégoire Moutel, Nathalie Duchange, Christophe Vayssière, Monique Kohler, Nicole Bouffet, Marie-Christine Hunsinger, Anne Kohler, Cécile Mager, Muriel Neumann, Christine Vayssière, Brigitte Viville, Christian Hervé, Israel Nisan. What about informed consent in first-trimester ultrasound screening for Down syndrome? Fetal diagnosis and therapy. vol 23. issue 3. 2008-06-04. PMID:18417975. |
we evaluate the level of information and informed consent given for the screening of down syndrome (ds) before the first-trimester ultrasound scan. |
2008-06-04 |
2023-08-12 |
Not clear |
| George P Henry, David W Britt, Mark I Evan. Screening advances and diagnostic choice: the problem of residual risk. Fetal diagnosis and therapy. vol 23. issue 4. 2008-06-04. PMID:18417998. |
data on down syndrome (ds) births for colorado from 1989 to 2005 were used to examine the implications of a decreasing use of amniocentesis. |
2008-06-04 |
2023-08-12 |
Not clear |
| Barbara Hämmerle, Carina Elizalde, Francisco J Tejedo. The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. The European journal of neuroscience. vol 27. issue 5. 2008-06-03. PMID:18364031. |
it is widely accepted that the neurological alterations in down syndrome (ds) are principally due to modifications in developmental processes. |
2008-06-03 |
2023-08-12 |
mouse |
| Bradley McPherson, Sandy Pui-Shan Lai, Kevin Kwong-Ki Leung, Iris Hoi-Yee N. Hearing loss in Chinese school children with Down syndrome. International journal of pediatric otorhinolaryngology. vol 71. issue 12. 2008-05-30. PMID:17936369. |
there is well-documented evidence in the literature concerning a high prevalence of deafness in children with down syndrome (ds). |
2008-05-30 |
2023-08-12 |
Not clear |
| Shirley Ramos da Rosa Utiyama, Renato Mitsunori Nisihara, Flávia Raphaela Nass, Nanci P Oliveira, Patrícia T Fiedler, Iara Taborda de Messias-Reaso. Autoantibodies in patients with Down syndrome: early senescence of the immune system or precocious markers for immunological diseases? Journal of paediatrics and child health. vol 44. issue 4. 2008-05-27. PMID:17927730. |
down syndrome (ds) patients present several immunological disturbances, with high rates of infections, malignancies and autoimmune phenomena. |
2008-05-27 |
2023-08-12 |
Not clear |
| Juan J Alio, Jose Lorenzo, Carmen Iglesia. Cranial base growth in patients with Down syndrome: a longitudinal study. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. vol 133. issue 5. 2008-05-27. PMID:18456147. |
the purpose of this study was to assess the growth of the cranial base in a sample of patients diagnosed with down syndrome (ds). |
2008-05-27 |
2023-08-12 |
Not clear |
| Jacques M Lignon, Zoë Bichler, Bruno Hivert, François E Gannier, Pierre Cosnay, José A del Rio, Danièle Migliore-Samour, Claire O Maléco. Altered heart rate control in transgenic mice carrying the KCNJ6 gene of the human chromosome 21. Physiological genomics. vol 33. issue 2. 2008-05-22. PMID:18303085. |
congenital heart defects (chd) are common in down syndrome (ds, trisomy 21). |
2008-05-22 |
2023-08-12 |
mouse |
| Donald E Kuhn, Gerard J Nuovo, Mickey M Martin, Geraldine E Malana, Adam P Pleister, Jinmai Jiang, Thomas D Schmittgen, Alvin V Terry, Katheleen Gardiner, Elizabeth Head, David S Feldman, Terry S Elto. Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts. Biochemical and biophysical research communications. vol 370. issue 3. 2008-05-22. PMID:18387358. |
down syndrome (ds), or trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. |
2008-05-22 |
2023-08-12 |
human |