| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robin Roberson, Laura Toso, Daniel Abebe, Catherine Y Spon. Altered expression of KIF17, a kinesin motor protein associated with NR2B trafficking, may mediate learning deficits in a Down syndrome mouse model. American journal of obstetrics and gynecology. vol 198. issue 3. 2008-04-08. PMID:18313453. |
mouse models for down syndrome have been studied and found to have developmental and learning deficits, including the ts65dn (ds) mouse model. |
2008-04-08 |
2023-08-12 |
mouse |
| M Guijarro, C Valero, B Paule, J Gonzalez-Macias, J A Rianch. Bone mass in young adults with Down syndrome. Journal of intellectual disability research : JIDR. vol 52. issue Pt 3. 2008-04-03. PMID:18261017. |
down syndrome (ds) is a frequent cause of intellectual disability. |
2008-04-03 |
2023-08-12 |
Not clear |
| F A Conners, C J Rosenquist, L Arnett, M S Moore, L E Hum. Improving memory span in children with Down syndrome. Journal of intellectual disability research : JIDR. vol 52. issue Pt 3. 2008-04-03. PMID:18261023. |
down syndrome (ds) is characterized by impaired memory span, particularly auditory verbal memory span. |
2008-04-03 |
2023-08-12 |
Not clear |
| Carla Pinto Moura, Luís Miguel Cunha, Helena Vilarinho, Maria João Cunha, Diamantino Freitas, Miguel Palha, Siegfried M Pueschel, M Pais-Clement. Voice parameters in children with Down syndrome. Journal of voice : official journal of the Voice Foundation. vol 22. issue 1. 2008-04-02. PMID:17014985. |
down syndrome (ds) is the most frequent chromosomal disorder. |
2008-04-02 |
2023-08-12 |
Not clear |
| Cesar A Sommer, Erika C Pavarino-Bertelli, Eny M Goloni-Bertollo, Flavio Henrique-Silv. Identification of dysregulated genes in lymphocytes from children with Down syndrome. Genome. vol 51. issue 1. 2008-04-01. PMID:18356936. |
global transcriptome studies attempting to analyze the consequences of trisomy in down syndrome (ds) tissues have reported conflicting results, which have led to the suggestion that the analysis of specific tissues or cell types may be more productive. |
2008-04-01 |
2023-08-12 |
human |
| Yingyao Chen, Xu Qian, Jie Zhang, Jun Li, Annie Chu, Stuart O Schweitze. Preliminary study into the economic burden of Down syndrome in China. Birth defects research. Part A, Clinical and molecular teratology. vol 82. issue 1. 2008-03-31. PMID:18022893. |
to measure the economic burden of down syndrome (ds) in china is to facilitate strategic planning development for managing and preventing ds. |
2008-03-31 |
2023-08-12 |
Not clear |
| Y Ge, K M LaFiura, A A Dombkowski, Q Chen, S G Payton, S A Buck, S Salagrama, A E Diakiw, L H Matherly, J W Tau. The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. Leukemia. vol 22. issue 3. 2008-03-27. PMID:18094719. |
acute myeloid leukemia (aml) in down syndrome (ds) children has several unique features including a predominance of the acute megakaryocytic leukemia (amkl) phenotype, higher event-free survivals compared to non-ds children using cytosine arabinoside (ara-c)/anthracycline-based protocols and a uniform presence of somatic mutations in the x-linked transcription factor gene, gata1. |
2008-03-27 |
2023-08-12 |
Not clear |
| Erik Forestier, Shai Izraeli, Berna Beverloo, Oskar Haas, Andrea Pession, Kyra Michalová, Batia Stark, Christine J Harrison, Andrea Teigler-Schlegel, Bertil Johansso. Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study. Blood. vol 111. issue 3. 2008-03-26. PMID:17971484. |
children with down syndrome (ds) have a markedly increased risk of acute lymphoblastic leukemia (all) and acute myeloid leukemia (aml). |
2008-03-26 |
2023-08-12 |
Not clear |
| Johanna R Price, Joanne E Roberts, Elizabeth A Hennon, Mary C Berni, Kathleen L Anderson, John Sideri. Syntactic complexity during conversation of boys with fragile X syndrome and Down syndrome. Journal of speech, language, and hearing research : JSLHR. vol 51. issue 1. 2008-03-19. PMID:18230852. |
this study compared the syntax of boys who have fragile x syndrome (fxs) with and without autism spectrum disorder (asd) with that of (a) boys who have down syndrome (ds) and (b) typically developing (td) boys. |
2008-03-19 |
2023-08-12 |
Not clear |
| D Masjkey, S Bhattacharya, S Dhungel, C B Jha, S Shrestha, S R Ghimire, D Ra. Utility of phenotypic dermal indices in the detection of Down syndrome patients. Nepal Medical College journal : NMCJ. vol 9. issue 4. 2008-03-19. PMID:18298007. |
down syndrome (ds) is the most common cause of mental retardation. |
2008-03-19 |
2023-08-12 |
Not clear |
| Ronald H W Cheng, W Keung Leung, Esmonde F Corbe. Non-surgical periodontal therapy with adjunctive chlorhexidine use in adults with down syndrome: a prospective case series. Journal of periodontology. vol 79. issue 2. 2008-03-18. PMID:18251655. |
subjects with down syndrome (ds) experience a high prevalence of periodontal disease, and the management of this disease in subjects with ds is a challenge for oral health care providers. |
2008-03-18 |
2023-08-12 |
human |
| J M Biselli, E M Goloni-Bertollo, B L Zampieri, R Haddad, M N Eberlin, E C Pavarino-Bertell. Genetic polymorphisms involved in folate metabolism and elevated plasma concentrations of homocysteine: maternal risk factors for Down syndrome in Brazil. Genetics and molecular research : GMR. vol 7. issue 1. 2008-03-18. PMID:18273817. |
the aim of the present study was to investigate the effect of polymorphisms c677t and a1298c in the methylenetetrahydrofolate reductase (mthfr) gene, a2756g in methionine synthase reductase (mtr) gene and a80g in reduced folate carrier 1 (rfc1) gene, and plasma homocysteine (hcy), on the maternal risk for down syndrome (ds). |
2008-03-18 |
2023-08-12 |
Not clear |
| Sheela N Magge, Kristen L O'Neill, Justine Shults, Virginia A Stallings, Nicolas Stettle. Leptin levels among prepubertal children with Down syndrome compared with their siblings. The Journal of pediatrics. vol 152. issue 3. 2008-03-18. PMID:18280834. |
to compare levels of leptin and other obesity-related hormones in prepubertal children with down syndrome (ds), a population at high obesity risk, and those in unaffected siblings to better understand the pathophysiology of obesity in children with ds. |
2008-03-18 |
2023-08-12 |
Not clear |
| Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung, Woo-Joo Son. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease. Journal of neurochemistry. vol 104. issue 5. 2008-03-14. PMID:18005339. |
most individuals with down syndrome (ds) show an early-onset of alzheimer's disease (ad), which potentially results from the presence of an extra copy of a segment of chromosome 21. |
2008-03-14 |
2023-08-12 |
mouse |
| Andrea S McDuffie, Heidi A Sindberg, Linda J Hesketh, Robin S Chapma. Use of speaker intent and grammatical cues in fast-mapping by adolescents with Down syndrome. Journal of speech, language, and hearing research : JSLHR. vol 50. issue 6. 2008-03-13. PMID:18055772. |
the authors asked whether adolescents with down syndrome (ds) could fast-map novel nouns and verbs when word learning depended on using the speaker's pragmatic or syntactic cues. |
2008-03-13 |
2023-08-12 |
Not clear |
| Rosangela Viana Andrade, Suelly Cecília Olivan Limong. [The emergence of expressive communication in the child with Down syndrome]. Pro-fono : revista de atualizacao cientifica. vol 19. issue 4. 2008-03-13. PMID:18200389. |
expressive communication in the child with down syndrome (ds). |
2008-03-13 |
2023-08-12 |
Not clear |
| Giuseppe Esposito, Jaime Imitola, Jie Lu, Daniele De Filippis, Caterina Scuderi, Vijay S Ganesh, Rebecca Folkerth, Jonathan Hecht, Soojung Shin, Teresa Iuvone, Jonathan Chesnut, Luca Steardo, Volney Shee. Genomic and functional profiling of human Down syndrome neural progenitors implicates S100B and aquaporin 4 in cell injury. Human molecular genetics. vol 17. issue 3. 2008-03-12. PMID:17984171. |
down syndrome (ds) is caused by trisomy of chromosome 21 and is characterized by mental retardation, seizures and premature alzheimer's disease. |
2008-03-12 |
2023-08-12 |
human |
| Gina Kirsammer, Sarah Jilani, Hui Liu, Elizabeth Davis, Sandeep Gurbuxani, Michelle M Le Beau, John D Crispin. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. vol 111. issue 2. 2008-03-11. PMID:17901249. |
children with down syndrome (ds) display macrocytosis, thrombocytosis, and a 500-fold increased risk of developing megakaryocytic leukemia; however, the specific effects of trisomy 21 on hematopoiesis remain poorly defined. |
2008-03-11 |
2023-08-12 |
mouse |
| Anne Ronan, Kerry Fagan, Louise Christie, Jeffrey Conroy, Norma J Nowak, Gillian Turne. Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical region. Journal of medical genetics. vol 44. issue 7. 2008-03-06. PMID:17237124. |
all had the facial gestalt of down syndrome (ds). |
2008-03-06 |
2023-08-12 |
Not clear |
| Ana Lloret, Rita Calzone, Christina Dunster, Paola Manini, Marco d'Ischia, Paolo Degan, Frank J Kelly, Federico V Pallardó, Adriana Zatterale, Giovanni Pagan. Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases. Free radical biology & medicine. vol 44. issue 4. 2008-03-06. PMID:18053816. |
a comparative evaluation is reported of pro-oxidant states in 82 patients with ataxia telangectasia (at), bloom syndrome (bs), down syndrome (ds), fanconi anemia (fa), werner syndrome (ws), and xeroderma pigmentosum (xp) vs 98 control donors. |
2008-03-06 |
2023-08-12 |
Not clear |