| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ronald H W Cheng, W Keung Leung, Esmonde F Corbet, Nigel M Kin. Oral health status of adults with Down syndrome in Hong Kong. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 27. issue 4. 2007-11-19. PMID:17972443. |
the aim of this survey was to study the oral health status of hong kong chinese adults with down syndrome (ds). |
2007-11-19 |
2023-08-12 |
human |
| Christian Arriagada, César Astorga, Illani Atwater, Eduardo Rojas, David Mears, Raúl Caviedes, Pablo Caviede. Endosomal abnormalities related to amyloid precursor protein in cholesterol treated cerebral cortex neuronal cells derived from trisomy 16 mice, an animal model of Down syndrome. Neuroscience letters. vol 423. issue 2. 2007-11-13. PMID:17706358. |
the cnh and ctb cell lines are derived from the cerebral cortex of normal and trisomy 16 mice, an animal model of human trisomy 21, down syndrome (ds), and represent in vitro models to study cellular events associated with the human condition. |
2007-11-13 |
2023-08-12 |
mouse |
| M Grynberg, O Graesslin, J Teyssedre, C Quereux, D Gaillard, F Carré-Pigeo. Prenatal diagnosis in monozygotic twins with Down syndrome who had different phenotypes. Prenatal diagnosis. vol 27. issue 6. 2007-11-09. PMID:17345584. |
we report the case of monozygotic (mz) male twin fetuses with different down syndrome (ds) phenotypes. |
2007-11-09 |
2023-08-12 |
Not clear |
| Mario A Cleves, Charlotte A Hobbs, Phillip A Cleves, John M Tilford, T M Bird, James M Robbin. Congenital defects among liveborn infants with Down syndrome. Birth defects research. Part A, Clinical and molecular teratology. vol 79. issue 9. 2007-11-08. PMID:17696161. |
many infants with down syndrome (ds) have co-occurring congenital malformations requiring intensive surgical and medical management. |
2007-11-08 |
2023-08-12 |
Not clear |
| Robert C Barnhart, Barbara Connoll. Aging and Down syndrome: implications for physical therapy. Physical therapy. vol 87. issue 10. 2007-11-08. PMID:17712035. |
down syndrome (ds) is the most frequent chromosomal cause of developmental delays. |
2007-11-08 |
2023-08-12 |
Not clear |
| Lina Chakrabarti, Zygmunt Galdzicki, Tarik F Hayda. Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 43. 2007-11-08. PMID:17959791. |
trisomy 21, one of the most prevalent congenital birth defects, results in a constellation of phenotypes collectively termed down syndrome (ds). |
2007-11-08 |
2023-08-12 |
mouse |
| Giusi I Forte, Maria Piccione, Letizia Scola, Antonino Crivello, Cristina Galfano, Massimiliano M Corsi, Martina Chiappelli, Giuseppina Candore, Mario Giuffrè, Roberto Verna, Federico Licastro, Giovanni Corsello, Calogero Caruso, Domenico Li. Apolipoprotein E genotypic frequencies among Down syndrome patients imply early unsuccessful aging for ApoE4 carriers. Rejuvenation research. vol 10. issue 3. 2007-11-07. PMID:17559337. |
down syndrome (ds) might be considered a model for unsuccessful and early aging, possibly accelerated for those who carry the apoe4 allele associated with common age-related diseases, e.g., alzheimer's disease and a poor prognosis after acute myocardial infarction, causing lower apoe4 frequencies among the very old in general populations. |
2007-11-07 |
2023-08-12 |
human |
| Giusi I Forte, Maria Piccione, Letizia Scola, Antonino Crivello, Cristina Galfano, Massimiliano M Corsi, Martina Chiappelli, Giuseppina Candore, Mario Giuffrè, Roberto Verna, Federico Licastro, Giovanni Corsello, Calogero Caruso, Domenico Li. Apolipoprotein E genotypic frequencies among Down syndrome patients imply early unsuccessful aging for ApoE4 carriers. Rejuvenation research. vol 10. issue 3. 2007-11-07. PMID:17559337. |
these results highlight ds as a model to understand the role of apoe4 allele in unsuccessful ageing considering that a number of proinflammatory supernumerary genes (cu/zn superoxide dismutase, ets-2 transcription factors, down syndrome critical region 1, stress-inducible factor, interferon-alpha receptor and the amyloid precursor protein) are located on chromosome 21 and are implied in the pathologic processes of ds. |
2007-11-07 |
2023-08-12 |
human |
| Clara S Moore, Randall J Rope. The power of comparative and developmental studies for mouse models of Down syndrome. Mammalian genome : official journal of the International Mammalian Genome Society. vol 18. issue 6-7. 2007-11-07. PMID:17653795. |
since the genetic basis for down syndrome (ds) was described, understanding the causative relationship between genes at dosage imbalance and phenotypes associated with ds has been a principal goal of researchers studying trisomy 21 (ts21). |
2007-11-07 |
2023-08-12 |
mouse |
| Pavel V Belichenko, Alexander M Kleschevnikov, Ahmad Salehi, Charles J Epstein, William C Moble. Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships. The Journal of comparative neurology. vol 504. issue 4. 2007-11-06. PMID:17663443. |
down syndrome (ds) is caused by trisomy of human chromosome 21. |
2007-11-06 |
2023-08-12 |
mouse |
| Andrea Contestabile, Tatiana Fila, Claudio Ceccarelli, Paola Bonasoni, Laura Bonapace, Donatella Santini, Renata Bartesaghi, Elisabetta Cian. Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice. Hippocampus. vol 17. issue 8. 2007-10-31. PMID:17546680. |
down syndrome (ds), the leading genetic cause of mental retardation, is characterized by reduced number of cortical neurons and brain size. |
2007-10-31 |
2023-08-12 |
mouse |
| Sharon R Pine, Qianxu Guo, Changhong Yin, Somasundaram Jayabose, Charlotte M Druschel, Claudio Sandova. Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome. Blood. vol 110. issue 6. 2007-10-30. PMID:17576817. |
somatic mutations in the gata1 gene are present in almost all cases of down syndrome (ds)-associated acute megakaryoblastic leukemia (amkl) and transient leukemia (tl). |
2007-10-30 |
2023-08-12 |
Not clear |
| Eun Jung Lee, Jae Youn Lee, Su Ryeon Seo, Kwang Chul Chun. Overexpression of DSCR1 blocks zinc-induced neuronal cell death through the formation of nuclear aggregates. Molecular and cellular neurosciences. vol 35. issue 4. 2007-10-30. PMID:17596961. |
the down syndrome (ds) candidate region gene 1 (dscr1) is localized near ds critical region on chromosome 21 and is overexpressed in the brains of ds patients. |
2007-10-30 |
2023-08-12 |
Not clear |
| G I Orsmond, M M Seltze. Siblings of individuals with autism or Down syndrome: effects on adult lives. Journal of intellectual disability research : JIDR. vol 51. issue Pt 9. 2007-10-30. PMID:17845237. |
in this study, we examine instrumental and affective involvement in the sibling relationship for adults who have a brother or sister with an autism spectrum disorder (asd) or down syndrome (ds). |
2007-10-30 |
2023-08-12 |
Not clear |
| Melanie A Porter, Max Coltheart, Robyn Langdo. The neuropsychological basis of hypersociability in Williams and Down syndrome. Neuropsychologia. vol 45. issue 12. 2007-10-25. PMID:17597166. |
people with down syndrome (ds) can also do so, but to a lesser degree. |
2007-10-25 |
2023-08-12 |
Not clear |
| R Thiel, Steven Wm Fowke. Down syndrome and thyroid dysfunction: should nutritional support be the first-line treatment? Medical hypotheses. vol 69. issue 4. 2007-10-24. PMID:17382480. |
individuals with down syndrome (ds) not only have increased risk of hypothyroidism, they also tend to develop a relatively novel mild form of neonatal hypothyroidism. |
2007-10-24 |
2023-08-12 |
cattle |
| Fabio Coppedè, Renato Colognato, Alessia Bonelli, Guja Astrea, Stefania Bargagna, Gabriele Siciliano, Lucia Miglior. Polymorphisms in folate and homocysteine metabolizing genes and chromosome damage in mothers of Down syndrome children. American journal of medical genetics. Part A. vol 143A. issue 17. 2007-10-23. PMID:17702010. |
we recently observed an association between combinations of polymorphisms in the methylenetetrahydrofolate reductase (mthfr 677c > t or 1298a > c) and reduced folate carrier (rfc-1 80g > a) genes and the risk of a down syndrome (ds) pregnancy in young italian women. |
2007-10-23 |
2023-08-12 |
Not clear |
| Claudia Dellavia, Chiarella Sforza, Fabiana Orlando, Paolo Ottolina, Fabrizio Pregliasco, Virgilio F Ferrari. Three-dimensional hard tissue palatal size and shape in Down syndrome subjects. European journal of orthodontics. vol 29. issue 4. 2007-10-23. PMID:17702802. |
the aim of the present study was to evaluate palatal morphology in down syndrome (ds) subjects, focusing on the effect of dental formula on the hard palate to assist clinicians when planning dental rehabilitation. |
2007-10-23 |
2023-08-12 |
human |
| M El-Ruby, N A Hemly, M S Zak. Maternal balanced translocation (4;21) leading to an offspring with partial duplication of 4q and 21q without phenotypic manifestations of Down syndrome. Genetic counseling (Geneva, Switzerland). vol 18. issue 2. 2007-10-16. PMID:17710874. |
in spite of detection of most of the 3 copies of chromosome 21, specific features of down syndrome (ds) were lacked in this patient, except for notable bilateral symmetrical calcification of basal ganglia. |
2007-10-16 |
2023-08-12 |
Not clear |
| Mohammed Rachidi, Carmela Lopes, Maher Costantine, Jean-Maurice Delaba. C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome. DNA research : an international journal for rapid publication of reports on genes and genomes. vol 12. issue 3. 2007-10-12. PMID:16303751. |
among these, down syndrome (ds) is the most frequent genetic cause of mental retardation. |
2007-10-12 |
2023-08-12 |
mouse |