| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lisa E Olson, Randall J Roper, Crystal L Sengstaken, Elizabeth A Peterson, Veronica Aquino, Zygmunt Galdzicki, Richard Siarey, Mikhail Pletnikov, Timothy H Moran, Roger H Reeve. Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice. Human molecular genetics. vol 16. issue 7. 2007-08-28. PMID:17339268. |
trisomic ts65dn mice show direct parallels with many phenotypes of down syndrome (ds), including effects on the structure of cerebellum and hippocampus. |
2007-08-28 |
2023-08-12 |
mouse |
| Caterina Proto, Daniela Romualdi, Rosa Maria Cento, Corrado Romano, Giuseppe Campagna, Antonio Lanzon. Free and total leptin serum levels and soluble leptin receptors levels in two models of genetic obesity: the Prader-Willi and the Down syndromes. Metabolism: clinical and experimental. vol 56. issue 8. 2007-08-23. PMID:17618952. |
alterations in energy balance and feeding behavior and the subsequent high frequency of obesity are hallmarks of 2 chromosomal diseases: the prader-willi syndrome (pws) and the down syndrome (ds). |
2007-08-23 |
2023-08-12 |
human |
| Akira Shimada, Yasuhide Hayashi, Mizuho Ogasawara, Myoung-Ja Park, Masahiko Katoh, Hisanori Minakami, Toshiyuki Kitoh, Seiji Kojima, Keisei Kawa, Hirokazu Kimur. Pro-inflammatory cytokinemia is frequently found in Down syndrome patients with hematological disorders. Leukemia research. vol 31. issue 9. 2007-08-22. PMID:17055049. |
down syndrome (ds) patients are frequently complicated with infections, autoimmune phenomena and hematological disorders, including transient abnormal myelopoiesis (tam) in infancy and acute megakaryoblastic leukaemia (amkl) in later life. |
2007-08-22 |
2023-08-12 |
Not clear |
| b' S\\xc3\\xadlvia Porta, Selma A Serra, Meritxell Huch, Miguel A Valverde, Franc Llorens, Xavier Estivill, Maria L Arbon\\xc3\\xa9s, Eul\\xc3\\xa0lia Mart\\xc3\\xa. RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration. Human molecular genetics. vol 16. issue 9. 2007-08-20. PMID:17341486.' |
regulator of calcineurin 1 (rcan1 or dscr1) is a dose-sensitive gene whose overexpression has been linked to down syndrome (ds) and alzheimer's disease (ad) neuropathology and to the response of cells to stress stimuli. |
2007-08-20 |
2023-08-12 |
Not clear |
| Yan-Xia Wang, Shan-Shan Mao, Chun-Hong Xie, Yu-Feng Qin, Zhi-Wei Zhu, Jian-Ying Zhan, Jie Shao, Rong Li, Zheng-Yan Zha. Study on the social adaptation of Chinese children with down syndrome. Yonsei medical journal. vol 48. issue 3. 2007-08-20. PMID:17594148. |
to evaluate social adjustment and related factors among chinese children with down syndrome (ds). |
2007-08-20 |
2023-08-12 |
Not clear |
| B T Costa-Carvalho, R M A Martinez, A T N Dias, C A Kubo, P Barros-Nunes, L Leiva, D Solé, M M S Carneiro-Sampaio, C K Naspitz, R U Sorense. Antibody response to pneumococcal capsular polysaccharide vaccine in Down syndrome patients. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 39. issue 12. 2007-08-14. PMID:17160268. |
the majority of children with down syndrome (ds) tend to have frequent bacterial infections including recurrent respiratory infections. |
2007-08-14 |
2023-08-12 |
human |
| Roger H Reeve. Down syndrome mouse models are looking up. Trends in molecular medicine. vol 12. issue 6. 2007-08-08. PMID:16677859. |
a new mouse model of down syndrome (ds) carries a copy of human chromosome 21 (hsa21), in addition to a full complement of mouse chromosomes. |
2007-08-08 |
2023-08-12 |
mouse |
| Linda D Nelson, Kevin E Scheibel, John M Ringman, James W Sayr. An experimental approach to detecting dementia in Down syndrome: a paradigm for Alzheimer's disease. Brain and cognition. vol 64. issue 1. 2007-08-07. PMID:17383786. |
although, by middle age, individuals with down syndrome (ds) show an extraordinarily high prevalence of ad-type pathology, their severe idiopathic cognitive deficits tend to confound the clinical diagnosis of ad. |
2007-08-07 |
2023-08-12 |
Not clear |
| Elizabeth F Barnes, Joanne Roberts, Penny Mirrett, John Sideris, Jan Misenheime. A comparison of oral structure and oral-motor function in young males with fragile X syndrome and Down syndrome. Journal of speech, language, and hearing research : JSLHR. vol 49. issue 4. 2007-07-30. PMID:16908884. |
this study compared the oral structure and oral-motor skills of 59 boys with fragile x syndrome (fxs), 34 boys with down syndrome (ds), and 36 developmentally similar typically developing (td) boys. |
2007-07-30 |
2023-08-12 |
human |
| David Keinan, Patricia Smith, Uri Zilberma. Microstructure and chemical composition of primary teeth in children with Down syndrome and cerebral palsy. Archives of oral biology. vol 51. issue 10. 2007-07-24. PMID:16756941. |
to test this hypothesis we examined exfoliated and extracted lower second primary molars of children with down syndrome (ds) and cerebral palsy (cp). |
2007-07-24 |
2023-08-12 |
Not clear |
| Srinivasa R Nagalla, Jacob A Canick, Thomas Jacob, Kimberly A Schneider, Ashok P Reddy, Archana Thomas, Surendra Dasari, Xinfang Lu, Jodi A Lapidus, Geralyn M Lambert-Messerlian, Michael G Gravett, Charles T Roberts, David Luthy, Fergal D Malone, Mary E D'Alto. Proteomic analysis of maternal serum in down syndrome: identification of novel protein biomarkers. Journal of proteome research. vol 6. issue 4. 2007-07-24. PMID:17373838. |
down syndrome (ds) is the most prevalent chromosomal disorder, accounting for significant morbidity and mortality. |
2007-07-24 |
2023-08-12 |
human |
| E Head, I T Lott, D Patterson, E Doran, R J Haie. Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention. Journal of Alzheimer's disease : JAD. vol 11. issue 1. 2007-07-16. PMID:17361036. |
adults with down syndrome (ds) develop alzheimer disease (ad) pathology progressively with age but clinical signs of dementia are delayed by at least 10 years after the first signs of disease. |
2007-07-16 |
2023-08-12 |
Not clear |
| Jeannie Visootsak, Stephanie Sherma. Neuropsychiatric and behavioral aspects of trisomy 21. Current psychiatry reports. vol 9. issue 2. 2007-07-16. PMID:17389125. |
down syndrome (ds), or trisomy 21, is the most common identifiable genetic cause of mental retardation. |
2007-07-16 |
2023-08-12 |
Not clear |
| Lindsay Bunn, Eric A Roy, Digby Elliot. Speech perception and motor control in children with Down syndrome. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. vol 13. issue 3. 2007-07-10. PMID:17453833. |
twelve children with and without down syndrome (ds) performed eight subtests of an apraxia battery to determine under what conditions children with ds had difficulty performing representational and nonrepresentational gestures. |
2007-07-10 |
2023-08-12 |
human |
| B E Otaigb. Down syndrome in one of non-identical Nigerian twins: a case report. Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria. vol 16. issue 1. 2007-07-10. PMID:17563974. |
down syndrome (ds) or trisomy 21 is the most frequent and best known trisomy in humans. |
2007-07-10 |
2023-08-12 |
Not clear |
| Warren B Zigman, Nicole Schupf, Edmund C Jenkins, Tiina K Urv, Benjamin Tycko, Wayne Silverma. Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome. Neuroscience letters. vol 416. issue 3. 2007-07-06. PMID:17353095. |
adults with down syndrome (ds) are at significantly higher risk of alzheimer's disease (ad) than the general population, but there is considerable variability in age at onset. |
2007-07-06 |
2023-08-12 |
human |
| Kristina Aldridge, Roger H Reeves, Lisa E Olson, Joan T Richtsmeie. Differential effects of trisomy on brain shape and volume in related aneuploid mouse models. American journal of medical genetics. Part A. vol 143A. issue 10. 2007-06-29. PMID:17431903. |
down syndrome (ds) results from inheritance of three copies of human chromosome 21 (hsa21). |
2007-06-29 |
2023-08-12 |
mouse |
| Kristina Aldridge, Roger H Reeves, Lisa E Olson, Joan T Richtsmeie. Differential effects of trisomy on brain shape and volume in related aneuploid mouse models. American journal of medical genetics. Part A. vol 143A. issue 10. 2007-06-29. PMID:17431903. |
ts1rhr is trisomic for genes corresponding to the so-called down syndrome critical region (dscr), which was purported to contain a dosage sensitive gene or genes responsible for many phenotypes of ds. |
2007-06-29 |
2023-08-12 |
mouse |
| Robyn A Wallac. Clinical audit of gastrointestinal conditions occurring among adults with Down syndrome attending a specialist clinic. Journal of intellectual & developmental disability. vol 32. issue 1. 2007-06-28. PMID:17365367. |
adults with down syndrome (ds) are predisposed to syndromic and environmental gastrointestinal conditions. |
2007-06-28 |
2023-08-12 |
Not clear |
| Beth A Smith, Masayoshi Kubo, David P Black, Kenneth G Holt, Beverly D Ulric. Effect of practice on a novel task--walking on a treadmill: preadolescents with and without Down syndrome. Physical therapy. vol 87. issue 6. 2007-06-28. PMID:17442836. |
the authors propose that preadolescents with down syndrome (ds) initially adapt to contexts that challenge their stability by increasing stiffness and impulse but, with practice, they will continue to adapt, but in the opposite direction, by decreasing stiffness and impulse. |
2007-06-28 |
2023-08-12 |
human |