| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susan E Puumala, Julie A Ross, Andrew F Olshan, Leslie L Robison, Franklin O Smith, Logan G Specto. Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a report from the Children's Oncology Group. Cancer. vol 110. issue 9. 2007-12-11. PMID:17849462. |
children with down syndrome (ds) have from 10 to 20 times the risk of developing acute leukemia than the general pediatric population. |
2007-12-11 |
2023-08-12 |
Not clear |
| Lisa A Ruble, Dana M Robso. Individual and environmental determinants of engagement in autism. Journal of autism and developmental disorders. vol 37. issue 8. 2007-12-10. PMID:17151800. |
analysis of 711 naturalistic goal-directed classroom behaviors of four school-age children with autism and four comparable children with down syndrome (ds) was conducted. |
2007-12-10 |
2023-08-12 |
Not clear |
| Gene S Fisch, Nancy Carpenter, Patricia N Howard-Peebles, Jeanette J A Holden, Jack Tarleton, Richard Simensen, Walter Nanc. Studies of age-correlated features of cognitive-behavioral development in children and adolescents with genetic disorders. American journal of medical genetics. Part A. vol 143A. issue 20. 2007-12-06. PMID:17853466. |
except for down syndrome (ds) and the fragile x mutation (fraxa), little is known about the longitudinal changes in cognitive-behavioral development in individuals with genetic abnormalities producing learning disabilities (ld) or mental retardation (mr). |
2007-12-06 |
2023-08-12 |
Not clear |
| Johann K Hitzle. Acute megakaryoblastic leukemia in Down syndrome. Pediatric blood & cancer. vol 49. issue 7 Suppl. 2007-12-06. PMID:17943965. |
children with down syndrome (ds) have a 10- to 20-fold increased risk of developing acute leukemia. |
2007-12-06 |
2023-08-12 |
Not clear |
| Jianhua Wu, Julia Looper, Beverly D Ulrich, Dale A Ulrich, Rosa M Angulo-Barros. Exploring effects of different treadmill interventions on walking onset and gait patterns in infants with Down syndrome. Developmental medicine and child neurology. vol 49. issue 11. 2007-12-06. PMID:17979862. |
two cohorts of participants were included to investigate the effects of different treadmill interventions on walking onset and gait patterns in infants with down syndrome (ds). |
2007-12-06 |
2023-08-12 |
human |
| T Gulesserian, E Engidawork, M Fountoulakis, G Lube. Manifold decrease of sialic acid synthase in fetal Down syndrome brain. Amino acids. vol 32. issue 1. 2007-11-29. PMID:16729195. |
down syndrome (ds, trisomy 21) is the most common genetic cause of mental retardation. |
2007-11-29 |
2023-08-12 |
Not clear |
| A Rani Elwy, Susan Michie, Theresa M Martea. Attributions and reported communication of a diagnosis of down syndrome. Health communication. vol 22. issue 2. 2007-11-27. PMID:17668991. |
this study investigates attributions and reported communication in 97 neonatologists who responded to a vignette-based questionnaire depicting a woman with 1 of 3 prenatal screening histories for down syndrome (ds) who had just given birth to a child with ds: not offered screening, refused screening, or received a false negative result on screening. |
2007-11-27 |
2023-08-12 |
Not clear |
| Ronald H W Cheng, W Keung Leung, Esmonde F Corbet, Nigel M Kin. Oral health status of adults with Down syndrome in Hong Kong. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 27. issue 4. 2007-11-19. PMID:17972443. |
the aim of this survey was to study the oral health status of hong kong chinese adults with down syndrome (ds). |
2007-11-19 |
2023-08-12 |
human |
| Christian Arriagada, César Astorga, Illani Atwater, Eduardo Rojas, David Mears, Raúl Caviedes, Pablo Caviede. Endosomal abnormalities related to amyloid precursor protein in cholesterol treated cerebral cortex neuronal cells derived from trisomy 16 mice, an animal model of Down syndrome. Neuroscience letters. vol 423. issue 2. 2007-11-13. PMID:17706358. |
the cnh and ctb cell lines are derived from the cerebral cortex of normal and trisomy 16 mice, an animal model of human trisomy 21, down syndrome (ds), and represent in vitro models to study cellular events associated with the human condition. |
2007-11-13 |
2023-08-12 |
mouse |
| M Grynberg, O Graesslin, J Teyssedre, C Quereux, D Gaillard, F Carré-Pigeo. Prenatal diagnosis in monozygotic twins with Down syndrome who had different phenotypes. Prenatal diagnosis. vol 27. issue 6. 2007-11-09. PMID:17345584. |
we report the case of monozygotic (mz) male twin fetuses with different down syndrome (ds) phenotypes. |
2007-11-09 |
2023-08-12 |
Not clear |
| Mario A Cleves, Charlotte A Hobbs, Phillip A Cleves, John M Tilford, T M Bird, James M Robbin. Congenital defects among liveborn infants with Down syndrome. Birth defects research. Part A, Clinical and molecular teratology. vol 79. issue 9. 2007-11-08. PMID:17696161. |
many infants with down syndrome (ds) have co-occurring congenital malformations requiring intensive surgical and medical management. |
2007-11-08 |
2023-08-12 |
Not clear |
| Robert C Barnhart, Barbara Connoll. Aging and Down syndrome: implications for physical therapy. Physical therapy. vol 87. issue 10. 2007-11-08. PMID:17712035. |
down syndrome (ds) is the most frequent chromosomal cause of developmental delays. |
2007-11-08 |
2023-08-12 |
Not clear |
| Lina Chakrabarti, Zygmunt Galdzicki, Tarik F Hayda. Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 43. 2007-11-08. PMID:17959791. |
trisomy 21, one of the most prevalent congenital birth defects, results in a constellation of phenotypes collectively termed down syndrome (ds). |
2007-11-08 |
2023-08-12 |
mouse |
| Giusi I Forte, Maria Piccione, Letizia Scola, Antonino Crivello, Cristina Galfano, Massimiliano M Corsi, Martina Chiappelli, Giuseppina Candore, Mario Giuffrè, Roberto Verna, Federico Licastro, Giovanni Corsello, Calogero Caruso, Domenico Li. Apolipoprotein E genotypic frequencies among Down syndrome patients imply early unsuccessful aging for ApoE4 carriers. Rejuvenation research. vol 10. issue 3. 2007-11-07. PMID:17559337. |
down syndrome (ds) might be considered a model for unsuccessful and early aging, possibly accelerated for those who carry the apoe4 allele associated with common age-related diseases, e.g., alzheimer's disease and a poor prognosis after acute myocardial infarction, causing lower apoe4 frequencies among the very old in general populations. |
2007-11-07 |
2023-08-12 |
human |
| Giusi I Forte, Maria Piccione, Letizia Scola, Antonino Crivello, Cristina Galfano, Massimiliano M Corsi, Martina Chiappelli, Giuseppina Candore, Mario Giuffrè, Roberto Verna, Federico Licastro, Giovanni Corsello, Calogero Caruso, Domenico Li. Apolipoprotein E genotypic frequencies among Down syndrome patients imply early unsuccessful aging for ApoE4 carriers. Rejuvenation research. vol 10. issue 3. 2007-11-07. PMID:17559337. |
these results highlight ds as a model to understand the role of apoe4 allele in unsuccessful ageing considering that a number of proinflammatory supernumerary genes (cu/zn superoxide dismutase, ets-2 transcription factors, down syndrome critical region 1, stress-inducible factor, interferon-alpha receptor and the amyloid precursor protein) are located on chromosome 21 and are implied in the pathologic processes of ds. |
2007-11-07 |
2023-08-12 |
human |
| Clara S Moore, Randall J Rope. The power of comparative and developmental studies for mouse models of Down syndrome. Mammalian genome : official journal of the International Mammalian Genome Society. vol 18. issue 6-7. 2007-11-07. PMID:17653795. |
since the genetic basis for down syndrome (ds) was described, understanding the causative relationship between genes at dosage imbalance and phenotypes associated with ds has been a principal goal of researchers studying trisomy 21 (ts21). |
2007-11-07 |
2023-08-12 |
mouse |
| Pavel V Belichenko, Alexander M Kleschevnikov, Ahmad Salehi, Charles J Epstein, William C Moble. Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships. The Journal of comparative neurology. vol 504. issue 4. 2007-11-06. PMID:17663443. |
down syndrome (ds) is caused by trisomy of human chromosome 21. |
2007-11-06 |
2023-08-12 |
mouse |
| Andrea Contestabile, Tatiana Fila, Claudio Ceccarelli, Paola Bonasoni, Laura Bonapace, Donatella Santini, Renata Bartesaghi, Elisabetta Cian. Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice. Hippocampus. vol 17. issue 8. 2007-10-31. PMID:17546680. |
down syndrome (ds), the leading genetic cause of mental retardation, is characterized by reduced number of cortical neurons and brain size. |
2007-10-31 |
2023-08-12 |
mouse |
| Sharon R Pine, Qianxu Guo, Changhong Yin, Somasundaram Jayabose, Charlotte M Druschel, Claudio Sandova. Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome. Blood. vol 110. issue 6. 2007-10-30. PMID:17576817. |
somatic mutations in the gata1 gene are present in almost all cases of down syndrome (ds)-associated acute megakaryoblastic leukemia (amkl) and transient leukemia (tl). |
2007-10-30 |
2023-08-12 |
Not clear |
| Eun Jung Lee, Jae Youn Lee, Su Ryeon Seo, Kwang Chul Chun. Overexpression of DSCR1 blocks zinc-induced neuronal cell death through the formation of nuclear aggregates. Molecular and cellular neurosciences. vol 35. issue 4. 2007-10-30. PMID:17596961. |
the down syndrome (ds) candidate region gene 1 (dscr1) is localized near ds critical region on chromosome 21 and is overexpressed in the brains of ds patients. |
2007-10-30 |
2023-08-12 |
Not clear |