| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Trish Parsons, Timothy M Ryan, Roger H Reeves, Joan T Richtsmeie. Microstructure of trabecular bone in a mouse model for Down syndrome. Anatomical record (Hoboken, N.J. : 2007). vol 290. issue 4. 2007-06-26. PMID:17514765. |
down syndrome (ds) is caused by trisomy of human chromosome 21 (hsa21) and results in a suite of dysmorphic phenotypes, including effects on the postcranial skeleton and the skull. |
2007-06-26 |
2023-08-12 |
mouse |
| Gavin H Tansley, Braydon L Burgess, Matt T Bryan, Yuan Su, Veronica Hirsch-Reinshagen, Jonathan Pearce, Jeniffer Y Chan, Anna Wilkinson, Jeanette Evans, Kathryn E Naus, Sean McIsaac, Kelley Bromley, Weihong Song, Hsui-Chiung Yang, Nan Wang, Ronald B DeMattos, Cheryl L Wellingto. The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein. Journal of lipid research. vol 48. issue 5. 2007-06-22. PMID:17293612. |
notably, the human abcg1 gene maps to chromosome 21q22.3, and individuals with down syndrome (ds) typically manifest with alzheimer's disease (ad) neuropathology in their 30s. |
2007-06-22 |
2023-08-12 |
human |
| Serena De Vita, Claire Mulligan, Suzanne McElwaine, Franca Dagna-Bricarelli, Monica Spinelli, Giuseppe Basso, Dean Nizetic, Jürgen Groe. Loss-of-function JAK3 mutations in TMD and AMKL of Down syndrome. British journal of haematology. vol 137. issue 4. 2007-06-18. PMID:17456055. |
acquired mutations activating janus kinase 3 (jak3) have been reported in down syndrome (ds) and non-ds patients with acute megakaryoblastic leukaemia (amkl). |
2007-06-18 |
2023-08-12 |
Not clear |
| Heiko Reutter, Regina C Betz, Michael Ludwig, Thomas M Boemer. MTHFR 677 TT genotype in a mother and her child with Down syndrome, atrioventricular canal and exstrophy of the bladder: implications of a mutual genetic risk factor? European journal of pediatrics. vol 165. issue 8. 2007-06-13. PMID:16602006. |
kluwer, new york, pp 199-206, 1999], we report only the second case of down syndrome (ds) associated with exstrophy of the bladder (eb). |
2007-06-13 |
2023-08-12 |
Not clear |
| V Prasher, G Gome. Natural history of thyroid function in adults with Down syndrome--10-year follow-up study. Journal of intellectual disability research : JIDR. vol 51. issue Pt 4. 2007-06-12. PMID:17326812. |
the natural history of thyroid function in adults with down syndrome (ds) is unknown. |
2007-06-12 |
2023-08-12 |
Not clear |
| J Price, J Roberts, N Vandergrift, G Marti. Language comprehension in boys with fragile X syndrome and boys with Down syndrome. Journal of intellectual disability research : JIDR. vol 51. issue Pt 4. 2007-06-12. PMID:17326813. |
we examined the receptive vocabulary, grammatical morphology and syntax skills of boys with fxs (who were additionally classified as having autism, autism spectrum, or no autism) and compared them to boys with down syndrome (ds) and typically developing (td) boys at similar non-verbal developmental levels. |
2007-06-12 |
2023-08-12 |
Not clear |
| Eero Pekkonen, Daria Osipova, Oili Sauna-Aho, Maria Arvi. Delayed auditory processing underlying stimulus detection in Down syndrome. NeuroImage. vol 35. issue 4. 2007-06-11. PMID:17363283. |
down syndrome (ds) is characterized by intellectual disability and development of dementia that are attributed to similar neuropathological features as observed in alzheimer's disease (ad). |
2007-06-11 |
2023-08-12 |
Not clear |
| Romain Favre, Nathalie Duchange, Christophe Vayssière, Monique Kohler, Nicole Bouffard, Marie-Chrsitine Hunsinger, Anne Kohler, Cécile Mager, Muriel Neumann, Christine Vayssière, Brigitte Viville, Christian Hervé, Grégoire Moute. How important is consent in maternal serum screening for Down syndrome in France? Information and consent evaluation in maternal serum screening for Down syndrome: a French study. Prenatal diagnosis. vol 27. issue 3. 2007-06-07. PMID:17238219. |
to evaluate the level of information and informed consent for maternal serum screening (mss) for down syndrome (ds) in the second trimester of pregnancy and analyse the exercise of autonomy towards the test by the women concerned. |
2007-06-07 |
2023-08-12 |
Not clear |
| S Perrone, M Longini, C V Bellieni, G Centini, A Kenanidis, L De Marco, F Petraglia, G Buonocor. Early oxidative stress in amniotic fluid of pregnancies with Down syndrome. Clinical biochemistry. vol 40. issue 3-4. 2007-06-04. PMID:17208212. |
some evidence suggests that oxidative stress, due to an imbalance between oxidants and antioxidants, occurs in babies with down syndrome (ds). |
2007-06-04 |
2023-08-12 |
Not clear |
| Pankaj D Mehta, George Capone, Amy Jewell, Robert L Freedlan. Increased amyloid beta protein levels in children and adolescents with Down syndrome. Journal of the neurological sciences. vol 254. issue 1-2. 2007-05-29. PMID:17275850. |
persons with down syndrome (ds) (40 years and older) have neuropathological changes characteristic of alzheimer disease (ad). |
2007-05-29 |
2023-08-12 |
Not clear |
| Nadia Sahir, Douglas E Brenneman, Joanna M Hil. Neonatal mice of the Down syndrome model, Ts65Dn, exhibit upregulated VIP measures and reduced responsiveness of cortical astrocytes to VIP stimulation. Journal of molecular neuroscience : MN. vol 30. issue 3. 2007-05-24. PMID:17401158. |
the ts65dn segmental mouse model of down syndrome (ds) possesses a triplication of the section of chromosome 16 that is most homologous to the human chromosome 21 that is trisomic in ds. |
2007-05-24 |
2023-08-12 |
mouse |
| F Licastro, G Dogliotti, G Goi, A E Malavazos, M Chiappelli, M M Cors. Oxidated low-density lipoproteins (oxLDL) and peroxides in plasma of Down syndrome patients. Archives of gerontology and geriatrics. vol 44 Suppl 1. 2007-05-18. PMID:17317457. |
a low prevalence of coronary artery disease is usually observed in adult down syndrome (ds) subjects, and these patients rarely die because of atherosclerotic complications. |
2007-05-18 |
2023-08-12 |
human |
| Hussein Shamaly, Corina Hartman, Shimon Pollack, Mohammad Hujerat, Rina Katz, Osnat Gideoni, Raanan Shami. Tissue transglutaminase antibodies are a useful serological marker for the diagnosis of celiac disease in patients with Down syndrome. Journal of pediatric gastroenterology and nutrition. vol 44. issue 5. 2007-05-01. PMID:17460490. |
celiac disease (cd) is overrepresented among patients with down syndrome (ds), who frequently lack any typical symptoms. |
2007-05-01 |
2023-08-12 |
Not clear |
| Fawzi Elhami Ali, Mahmoud A Al-Bustan, Waleed A Al-Busairi, Fatema A Al-Mulla, Emad Y Esbait. Cervical spine abnormalities associated with Down syndrome. International orthopaedics. vol 30. issue 4. 2007-04-26. PMID:16525818. |
atlantoaxial instability (aai) affects 10-20% of individuals with down syndrome (ds). |
2007-04-26 |
2023-08-12 |
human |
| Chie Harashima, David M Jacobowitz, Markus Stoffel, Lina Chakrabarti, Tarik F Haydar, Richard J Siarey, Zygmunt Galdzick. Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model. Cellular and molecular neurobiology. vol 26. issue 4-6. 2007-04-24. PMID:16783527. |
down syndrome (ds) arises from the presence of three copies of chromosome (chr.) |
2007-04-24 |
2023-08-12 |
mouse |
| Zuhal Hamurcu, Halil Demirtas, Turkan Patiroglu, Sefer Kumandas, Nalan Imamoglu, Yusuf Ozkul, Hamiyet Donmez-Altunta. Age-dependent decreases in mitogen-stimulation level and RNA content in peripheral blood mononuclear cells of Down syndrome patients. Cytometry. Part B, Clinical cytometry. vol 72. issue 1. 2007-04-20. PMID:17041944. |
the aim of the present study was to determine whether or not the phytohemagglutinin (pha)-activated proliferation and average rna content in peripheral blood mononuclear cells (pbmc) of down syndrome (ds) patients change with age. |
2007-04-20 |
2023-08-12 |
Not clear |
| K-Y Wang, K Hsieh, T Heller, P W Davidson, M P Janick. Carer reports of health status among adults with intellectual/developmental disabilities in Taiwan living at home and in institutions. Journal of intellectual disability research : JIDR. vol 51. issue Pt 3. 2007-04-11. PMID:17300413. |
the aim of the present study was to assess the health status of a cohort of adults with intellectual/developmental disabilities (i/dd) residing in family homes or institutions in taiwan and to examine whether morbidity varied with age, sex, existing diagnosis [down syndrome (ds), seizures, cerebral palsy (cp), intellectual disability (id) level] and residential status. |
2007-04-11 |
2023-08-12 |
Not clear |
| Michiel J M Volman, Jacqueline J W Visser, Gerty J L M Lensvelt-Mulder. Functional status in 5 to 7-year-old children with Down syndrome in relation to motor ability and performance mental ability. Disability and rehabilitation. vol 29. issue 1. 2007-04-10. PMID:17364754. |
to examine the contribution of motor ability and 'performance' mental ability on functional skills in children with down syndrome (ds). |
2007-04-10 |
2023-08-12 |
Not clear |
| Wieslaw K Dowjat, Tatyana Adayev, Izabela Kuchna, Krzysztof Nowicki, Sonia Palminiello, Yu Wen Hwang, Jerzy Wegie. Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome. Neuroscience letters. vol 413. issue 1. 2007-04-05. PMID:17145134. |
down syndrome (ds) is the most common genetic disorder associated with mental retardation (mr). |
2007-04-05 |
2023-08-12 |
mouse |
| Michael Christiansen, Tina Lindvig Sørensen, Bent Nørgaard-Pederse. Human placental lactogen is a first-trimester maternal serum marker of Down syndrome. Prenatal diagnosis. vol 27. issue 1. 2007-04-05. PMID:17154235. |
we analysed the potential of hpl as a first-trimester maternal serum-screening marker for fetal down syndrome (ds). |
2007-04-05 |
2023-08-12 |
human |